CN1353614A - 治疗慢性心脏病的方法 - Google Patents

治疗慢性心脏病的方法 Download PDF

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Publication number
CN1353614A
CN1353614A CN00805115A CN00805115A CN1353614A CN 1353614 A CN1353614 A CN 1353614A CN 00805115 A CN00805115 A CN 00805115A CN 00805115 A CN00805115 A CN 00805115A CN 1353614 A CN1353614 A CN 1353614A
Authority
CN
China
Prior art keywords
bpi
protein product
bpi protein
leu
circulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00805115A
Other languages
English (en)
Chinese (zh)
Inventor
B·P·吉洛伊尔
P·J·斯坎弄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TAXAS SYSTEM, University of, Regents of
Xoma Technology Ltd USA
Original Assignee
TAXAS SYSTEM, University of, Regents of
Xoma Technology Ltd USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TAXAS SYSTEM, University of, Regents of, Xoma Technology Ltd USA filed Critical TAXAS SYSTEM, University of, Regents of
Publication of CN1353614A publication Critical patent/CN1353614A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1751Bactericidal/permeability-increasing protein [BPI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN00805115A 1999-01-22 2000-01-21 治疗慢性心脏病的方法 Pending CN1353614A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11673699P 1999-01-22 1999-01-22
US60/116,736 1999-01-22

Publications (1)

Publication Number Publication Date
CN1353614A true CN1353614A (zh) 2002-06-12

Family

ID=22368911

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00805115A Pending CN1353614A (zh) 1999-01-22 2000-01-21 治疗慢性心脏病的方法

Country Status (11)

Country Link
US (3) US6509317B1 (enExample)
EP (1) EP1143996B1 (enExample)
JP (2) JP2002535282A (enExample)
CN (1) CN1353614A (enExample)
AT (1) ATE239492T1 (enExample)
AU (1) AU778001B2 (enExample)
CA (1) CA2359681A1 (enExample)
DE (1) DE60002552T2 (enExample)
MX (1) MXPA01007031A (enExample)
NZ (1) NZ513087A (enExample)
WO (1) WO2000043028A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1339424A2 (en) 2000-12-01 2003-09-03 XOMA Technology Ltd. Modulation of pericyte proliferation using bpi protein products or bpi inhibitors
WO2010062738A1 (en) * 2008-11-03 2010-06-03 Ut-Battelle, Llc Diagnosis and treatment of congenital heart defects using nell 1
US9974759B2 (en) * 2013-05-31 2018-05-22 Indiana University Research And Technology Corporation Beta 2 adrenoceptor antagonists for treating orthostatic hypotension
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643875A (en) 1994-01-24 1997-07-01 Friedmann; Nadav Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products
US5578568A (en) 1994-04-22 1996-11-26 Xoma Corporation Method of treating conditions associated with intestinal ischemia/reperfusion
US5646114A (en) * 1994-07-11 1997-07-08 Xoma Corporation Anti-protozoan methods
DK0914144T3 (da) * 1996-05-10 2001-04-09 Univ Texas Terapeutiske anvendelser af BPI-protein-produkter til human meningokokæmi

Also Published As

Publication number Publication date
JP2002535282A (ja) 2002-10-22
US6509317B1 (en) 2003-01-21
AU2734100A (en) 2000-08-07
DE60002552D1 (de) 2003-06-12
DE60002552T2 (de) 2004-02-26
EP1143996A2 (en) 2001-10-17
CA2359681A1 (en) 2000-07-27
EP1143996A4 (de) 2002-04-24
US20030216312A1 (en) 2003-11-20
WO2000043028A9 (en) 2001-09-20
JP2007126479A (ja) 2007-05-24
AU778001B2 (en) 2004-11-11
US20060171937A1 (en) 2006-08-03
ATE239492T1 (de) 2003-05-15
MXPA01007031A (es) 2004-08-12
WO2000043028A2 (en) 2000-07-27
EP1143996B1 (en) 2003-05-07
NZ513087A (en) 2003-02-28
WO2000043028A3 (en) 2000-11-30
US7045501B2 (en) 2006-05-16

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Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication