CN1353575A - 用树状细胞一肿瘤细胞或树状细胞一病毒细胞衍生的免疫原在体外诱导抗原特异性t－销细胞 - Google Patents

用树状细胞一肿瘤细胞或树状细胞一病毒细胞衍生的免疫原在体外诱导抗原特异性t－销细胞 Download PDF

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CN1353575A
CN1353575A CN00808298A CN00808298A CN1353575A CN 1353575 A CN1353575 A CN 1353575A CN 00808298 A CN00808298 A CN 00808298A CN 00808298 A CN00808298 A CN 00808298A CN 1353575 A CN1353575 A CN 1353575A
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cell
cells
dendritic
described method
tumor
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小L·D·法罗
W·斯托尔库斯
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University of Pittsburgh
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University of Pittsburgh
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/55—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells

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  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
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  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN00808298A 1999-03-31 2000-03-30 用树状细胞一肿瘤细胞或树状细胞一病毒细胞衍生的免疫原在体外诱导抗原特异性t－销细胞 Pending CN1353575A (zh)

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US28267999A 1999-03-31 1999-03-31
US09/282,679 1999-03-31

Publications (1)

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CN1353575A true CN1353575A (zh) 2002-06-12

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CN00808298A Pending CN1353575A (zh) 1999-03-31 2000-03-30 用树状细胞一肿瘤细胞或树状细胞一病毒细胞衍生的免疫原在体外诱导抗原特异性t－销细胞

Country Status (6)

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EP (1) EP1168924A4 (enExample)
JP (1) JP2002539805A (enExample)
CN (1) CN1353575A (enExample)
AU (1) AU4183100A (enExample)
CA (1) CA2367590A1 (enExample)
WO (1) WO2000057705A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102827826A (zh) * 2012-09-11 2012-12-19 赵永祥 一种诱导树突状细胞与肿瘤细胞融合的方法
CN103109191A (zh) * 2010-09-17 2013-05-15 洛菲厄斯生物科学有限责任公司 利用逆转录定量实时PCR(RT-qPCR)技术检测、区分和定量T细胞群体的方法
CN105532575A (zh) * 2016-01-14 2016-05-04 中国科学院昆明动物研究所 一种单纯疱疹病毒感染树鼩动物模型的构建、评估方法及其应用
WO2016145578A1 (en) * 2015-03-13 2016-09-22 Syz Cell Therapy Co. Methods of cancer treatment using activated t cells
US11248208B2 (en) 2018-03-30 2022-02-15 Syz Cell Therapy Co. Multiple antigen specific cell therapy methods

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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US20050169898A1 (en) 1997-04-15 2005-08-04 Jianlin Gong Cell fusions and methods of making and using the same
CA2286873C (en) 1997-04-15 2010-07-13 Dana-Farber Cancer Institute, Inc. Dendritic cell hybrids
WO2001029193A2 (de) * 1999-10-22 2001-04-26 Peter Leskovar Zellkonstrukte, die für die immuntherapie geeignet sind, deren herstellung und verwendung
EP1263928B1 (en) * 2000-02-11 2007-09-26 Dana-Farber Cancer Institute, Inc. Identification of antigenic peptides by cytotoxic t lymphocytes activated by dendritic cell hybrids
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
US7541184B2 (en) 2000-02-24 2009-06-02 Invitrogen Corporation Activation and expansion of cells
DE10164819A1 (de) * 2001-11-20 2005-05-19 Deml, Ludwig, Dr. Verfahren zur Identifizierung von Zielepitopen der T-Zell-vermittelten Immunantwort und zum Nachweis Epitop-spezifischer T-Zellen
ES2613957T3 (es) 2006-08-04 2017-05-29 Medimmune Limited Anticuerpos contra ERBB2
EP2606897A1 (en) 2011-12-22 2013-06-26 Laboratorios Del. Dr. Esteve, S.A. Methods and compositions for the treatment of diseases caused by enveloped viruses
CN104830793A (zh) * 2015-05-05 2015-08-12 杨光华 基于lmp-1抗原的dc细胞、靶向性免疫细胞群及其制备方法和用途
CA2985350A1 (en) 2015-05-08 2016-11-17 Wilson Wolf Manufacturing Improved culture methods and devices for testing
JP2018522880A (ja) 2015-07-02 2018-08-16 プライムヴァックス イミュノ−オンコロジー，インク． デングウイルス及び樹状細胞による併用療法のための組成物及び方法
CA2999881A1 (en) 2015-09-26 2017-03-30 PrimeVax Immuno-Oncology, Inc. Compositions and methods for producing dendritic cells
CN110139671A (zh) 2016-11-16 2019-08-16 普莱瓦克斯免疫肿瘤学公司 用于治疗癌症的组合免疫疗法
WO2018129202A1 (en) 2017-01-04 2018-07-12 PrimeVax Immuno-Oncology, Inc. Compositions and methods for therapy with dengue virus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69634750T2 (de) * 1995-03-31 2006-02-23 Université Libre de Bruxelles DENDRITENZELLEN/TUMORZELLEN Hybirde ZUR INDUKTION EINER ANTI-TUMOR ANTWORT
CA2286873C (en) * 1997-04-15 2010-07-13 Dana-Farber Cancer Institute, Inc. Dendritic cell hybrids
CA2318987A1 (en) * 1998-01-26 1999-07-29 Genzyme Corporation Immune effector cell hybrids

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103109191A (zh) * 2010-09-17 2013-05-15 洛菲厄斯生物科学有限责任公司 利用逆转录定量实时PCR(RT-qPCR)技术检测、区分和定量T细胞群体的方法
CN103109191B (zh) * 2010-09-17 2016-04-13 洛菲厄斯生物科学有限责任公司 利用逆转录定量实时PCR(RT-qPCR)技术检测、区分和定量T细胞群体的方法
CN102827826A (zh) * 2012-09-11 2012-12-19 赵永祥 一种诱导树突状细胞与肿瘤细胞融合的方法
WO2016145578A1 (en) * 2015-03-13 2016-09-22 Syz Cell Therapy Co. Methods of cancer treatment using activated t cells
CN107735492A (zh) * 2015-03-13 2018-02-23 深圳源正细胞医疗技术有限公司 使用活化t细胞治疗癌的方法
US10967054B2 (en) 2015-03-13 2021-04-06 Syz Cell Therapy Co. Methods of cancer treatment using activated T cells
US11219675B2 (en) 2015-03-13 2022-01-11 Syz Cell Therapy Co. Methods of cancer treatment using activated T cells
US11229689B2 (en) 2015-03-13 2022-01-25 Syz Cell Therapy Co. Methods of cancer treatment using activated T cells
US12312597B2 (en) 2015-03-13 2025-05-27 HRY Z (Shanghai) Biotech Co. Methods of cancer treatment using activated t cells
CN105532575A (zh) * 2016-01-14 2016-05-04 中国科学院昆明动物研究所 一种单纯疱疹病毒感染树鼩动物模型的构建、评估方法及其应用
US11248208B2 (en) 2018-03-30 2022-02-15 Syz Cell Therapy Co. Multiple antigen specific cell therapy methods

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CA2367590A1 (en) 2000-10-05
EP1168924A4 (en) 2002-09-04
WO2000057705A1 (en) 2000-10-05
AU4183100A (en) 2000-10-16
EP1168924A1 (en) 2002-01-09
JP2002539805A (ja) 2002-11-26

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