CN1345596A - Chinese medicinal preparation for nourishing Yin and promoting production of body liquid and preparation method thereof - Google Patents
Chinese medicinal preparation for nourishing Yin and promoting production of body liquid and preparation method thereof Download PDFInfo
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- CN1345596A CN1345596A CN 00125403 CN00125403A CN1345596A CN 1345596 A CN1345596 A CN 1345596A CN 00125403 CN00125403 CN 00125403 CN 00125403 A CN00125403 A CN 00125403A CN 1345596 A CN1345596 A CN 1345596A
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- herba dendrobii
- body fluid
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Abstract
The invention discloses a compound preparation of Chinese traditional medicine with functions of nourishing yin and increasing the body fluid, and its preparation method. The invented preparation is composed of dendrobium stem etc. and medicinal auxiliary materials. The forms of prepared drugs includes tea bag, oral liquid piece for keeping in mouth, capsule and granule. The preparation provides of features of easy to take the medicine, and taking it for long period.
Description
The present invention relates to Chinese medicine preparation, be specifically related to a kind of compound Chinese medicinal preparation and preparation method of YIN nourishing and the production of body fluid promoting.
China's Chinese medicine has more record to the Chinese medicine of YIN nourishing and the production of body fluid promoting, Herba Dendrobii promote the production of body fluid stomach reinforcing, clearing away heat and nourishing YIN, can be used for controlling consumption of body fluid caused by febrile disease, xerostomia excessive thirst, after being ill deficiency-heat, the moon to hinder order dark etc.For example the record Herba Dendrobii " is controlled plug in heating spontaneous perspiration, the carbuncle evacuation of pus " in " detailed outline ".Record Herba Dendrobii in " herbal classic " " that win is thin, reinforcing YIN-essence, obey thick the intestines and stomach for a long time by main damaging the spleen and stomach, eliminating impediment, the therapeutic method to keep the adverse QI flowing downwards, tonifying five ZANG-organs asthenia." Herba Dendrobii extract is special the forming of first-class Herba Dendrobii processing, have clearing away heat and nourishing YIN, nourishing the stomach to promote the production of body fluid effect, share with common Herba Dendrobii and can strengthen the effect of quenching the thirst, separating deficiency-heat.Herb Gynostemmae Pentaphylli contains gypenoside, and this Saponin is identical with ginsenoside's part The Nomenclature Composition and Structure of Complexes, thereby thinks that similar Radix Ginseng effect is arranged, and particularly has antifatigue effect, effect that promptly traditional Chinese medical science is thought has " QI invigorating ", and can also blood fat reducing, slow down aging.
The object of the invention is to utilize the traditional Chinese medical science effect of Herba Dendrobii extract, Herba Dendrobii and Herb Gynostemmae Pentaphylli, develops a kind of compound preparation.
The invention provides a kind of compound Chinese medicinal preparation of YIN nourishing and the production of body fluid promoting, said preparation is by being by weight: Herba Dendrobii extract 1-10 part, Herba Dendrobii 49-70 part, Herb Gynostemmae Pentaphylli 29-50 part and pharmaceutic adjuvant are formed.
The acute toxic test of the compound Chinese medicinal preparation of YIN nourishing and the production of body fluid promoting of the present invention (Herba Dendrobii extract tender tea leaves bagged steeping drug) is reported as follows: [test sample] Herba Dendrobii extract tender tea leaves are the bagged steeping drug that make at the broken ends of Chinese medicine such as Herba Dendrobii extract, Herba Dendrobii, Herb Gynostemmae Pentaphylli,
Being done by Shanghai Institute of Chinese Traditional Medicine institute new drug development provides.Test sample boils through water
Decoct 10 ', secondary merges decocting liquid altogether, after the filtered through gauze, and low temperature (<80
℃) descend evaporation and concentration to every milliliter of concentration that contains crude drug 2 grams, stand-by.[animal] Kunming mouse, male and female half and half, body weight 21-22g, moving by the experiment of new hilllock
The thing field provides.[result] is through trial test, with 0.2ml/10g, 0.3ml/10g, each filling of 0.4ml/10g
Three mices of stomach, none death.Then press maximal dose 0.4ml/10g (promptly
80g/kg) irritate 20 mices of stomach, observe a week, none death of animal as a result,
No overt toxicity skin should, think that test sample is to oral maximum anti-of chmice acute
The amount of being subjected to is greater than 80g/kg.
The stability test result of the compound Chinese medicinal preparation of YIN nourishing and the production of body fluid promoting of the present invention (Herba Dendrobii extract tender tea leaves bagged steeping drug) is as follows:
This product (10 bags are sealed in the plastic bag) is placed in the temperature and humidity regulator, and temperature is controlled at 37-40 ℃, and relative humidity is controlled at 70-80%, deposits three months, and assay is as follows:
The lot number project | ????????????1 | ???????????2 | ||
Standing time | Former state | Three months | Former state | Three months |
Character | Pistachio medicamental pulverata, gas delicate fragrance | With a left side | With a left side | With a left side |
Moisture content % | ????6.73 | ???7.08 | ???7.12 | ???7.34 |
Differentiate | ?????+ | ????+ | ????+ | ????+ |
Hygiology | Qualified | Qualified | Qualified | Qualified |
The quality standard of YIN nourishing and the production of body fluid promoting Chinese medicine preparation of the present invention (Herba Dendrobii extract tender tea leaves bagged steeping drug) is as follows: prescription is formed: Herba Dendrobii extract 5g, Herba Dendrobii 95g, Herb Gynostemmae Pentaphylli 100g, make 100 bag infusions.Character: this product be the tiny medicine of light olive drab(O not, gas delicate fragrance, the flavor slightly sweet.Differentiate: get this product 10g, add the 25ml80% alcohol heating reflux and extracted 1.5 hours, cooling
After-filtration, 60 ℃ of filtrates are evaporated to dried, add the 5ml1% dissolving with hydrochloric acid, filter,
Filtrate adds bismuth potassium iodide test solution 1-2, tangible reddish brown precipitation occurs.Check: 1, the uniformity: get wood product 1 bag, put on the glossy paper and tile, its surface is flattened,
The light place is observed, and should show uniform color and luster, no decorative pattern, mottle.
2, moisture content: get this product according to 30 pages of moisture of Chinese Pharmacopoeia (9 years, one one) appendix
Algoscopy (method) is measured, and moisture must not cross 9.0%.
3, content uniformity: must not surpass the regulation loading amount ± 7.0% usage and consumption: be taken after being infused in hot water or decoction a 1-2 bag, 2-3 time on the 1st with boiled water.Specification: every bag heavy 2g.Storage: sealing.
The health examination result of YIN nourishing and the production of body fluid promoting Chinese medicine preparation of the present invention (Herba Dendrobii extract tender tea leaves bagged steeping drug) is as follows:
Audit report:
The project lot number | Assorted bacterium (individual/gram) | Mycete (individual/gram) | Escherichia coli | The result |
????1 | ????1800 | ????250 | Do not detect | Qualified |
????2 | ????7300 | ????350 | Do not detect | Qualified |
Lot number | Character | Differentiate | The uniformity | Moisture content (%) | Content uniformity | Hygiology |
??1 | Qualified | Positive | Qualified | ??6.73 | Qualified | Qualified |
??2 | Qualified | Positive | Qualified | ??7.12 | Qualified | Qualified |
Another object of the present invention has provided the preparation method of above-mentioned YIN nourishing and the production of body fluid promoting Chinese medicine preparation, and this method is:
Get Herba Dendrobii extract inspection decontamination, spray the sterilization of 75% ethanol, wave most ethanol, 40 ℃ of dryings of low temperature are pulverized, and get the fine powder that does not pass through 100 orders by 60 orders, and are through 80 ℃ of constant temperature sterilizations 2 hours, standby;
Get the same method of Herba Dendrobii and handle, standby;
Get the same method of Herb Gynostemmae Pentaphylli of drying and handle, standby;
Get Herba Dendrobii extract, Herba Dendrobii, the Herb Gynostemmae Pentaphylli of above-mentioned processing, it is evenly mixed to press recipe quantity and pharmaceutic adjuvant, and the oral formulations of various dosage forms is made in the weighing packing.
YIN nourishing and the production of body fluid promoting Chinese medicine preparation of the present invention can be made multiple oral formulations, as: teabag, oral liquid, buccal tablet, capsule, granule etc.
The drug effect of the comprehensive three flavor Chinese medicines of YIN nourishing and the production of body fluid promoting Chinese medicine preparation of the present invention plays synergism, supplementing QI and nourishing YIN, and Tianjin heat is promoted the production of body fluid.The preparation property of medicine of the present invention is gentle, and taking convenience has no adverse reaction, and drink-service for a long time improves body constitution, body building, slow down aging.
Example 1
Prescription: Herba Dendrobii extract 5 grams, Herba Dendrobii 95 grams, Herb Gynostemmae Pentaphylli 100 grams
Get Herba Dendrobii extract 5 and restrain, spray sterilization with 75% ethanol, volatilization ethanol, 40 ℃ of dryings of low temperature are pulverized, and get the fine powder that does not pass through 100 orders by 60 orders, and are through 80 ℃ of constant temperature sterilizations 2 hours, standby; Get Herba Dendrobii 95 grams, Herb Gynostemmae Pentaphylli 100 grams respectively with the method processing, then three flavor medicine mixing weighings are distributed into 100 bags.Example 2
The exsiccant Herba Dendrobii extract 50 of learning from else's experience restrains, Herba Dendrobii 700 restrains, Herb Gynostemmae Pentaphylli 500 grams, adds water 10kg, merceration 3 hours, and heating and refluxing extraction is 1 hour then, filters, and filtrate to 5 ℃ following standing over night is removed small amount of precipitate.Water 20kg dissolves white sugar 5kg, citric acid 0.02kg, sodium benzoate 0.01kg in addition, and mixes with extracting solution, and thin up filters to 62.5L, and heat sterilization is filled into bottle, and every bottle of 250ml can make 250 bottles of health beverages.Example 3
Get Herba Dendrobii 15kg, Herb Gynostemmae Pentaphylli 10kg, add water 200kg, reflux, extract, 1.5 hours, residue adds water 150kg, reflux, extract, 1 hour, merge extractive liquid, concentrates, vacuum drying gets extractum 4kg, and adding Herba Dendrobii extract powder 1kg, starch 2kg, dimension intracrystalline are tieed up plain 1.695kg, sucrose 1kg, citric acid 5g, mixed, cross 60 orders, granulate then, add magnesium stearate 100g, Pulvis Talci 200g in the granule, mixed back tabletting makes 10,000 of the buccal tablets of every heavy 1g.
Claims (2)
1. the compound Chinese medicinal preparation of a YIN nourishing and the production of body fluid promoting, it is characterized in that said preparation is by being by weight: Herba Dendrobii extract 1-10 part, Herba Dendrobii 49-70 part, Herb Gynostemmae Pentaphylli 29-50 part and pharmaceutic adjuvant are formed.
2. the preparation method of the compound Chinese medicinal preparation of an a kind of YIN nourishing and the production of body fluid promoting as claimed in claim 1, it is characterized in that this method is to get Herba Dendrobii extract inspection decontamination, spray the sterilization of 75% ethanol, wave most ethanol, 40 ℃ of dryings of low temperature are pulverized, and get the fine powder that does not pass through 100 orders by 60 orders, through 80 ℃ of constant temperature sterilizations 2 hours, standby;
Get the same method of Herba Dendrobii and handle, standby;
Get the same method of Herb Gynostemmae Pentaphylli of drying and handle, standby;
Get Herba Dendrobii extract, Herba Dendrobii, the Herb Gynostemmae Pentaphylli of above-mentioned processing, it is evenly mixed to press recipe quantity and pharmaceutic adjuvant, and the oral formulations of various dosage forms is made in the weighing packing.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 00125403 CN1345596A (en) | 2000-09-26 | 2000-09-26 | Chinese medicinal preparation for nourishing Yin and promoting production of body liquid and preparation method thereof |
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CN 00125403 CN1345596A (en) | 2000-09-26 | 2000-09-26 | Chinese medicinal preparation for nourishing Yin and promoting production of body liquid and preparation method thereof |
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CN1345596A true CN1345596A (en) | 2002-04-24 |
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CN 00125403 Pending CN1345596A (en) | 2000-09-26 | 2000-09-26 | Chinese medicinal preparation for nourishing Yin and promoting production of body liquid and preparation method thereof |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1311855C (en) * | 2004-07-12 | 2007-04-25 | 浙江省中药研究所 | Officinal Dendrobium stem capsule and preparing method |
CN102132759A (en) * | 2011-04-27 | 2011-07-27 | 贾晋科 | Bagged winter health care tea |
CN101695328B (en) * | 2009-10-27 | 2012-11-14 | 白汉玉 | Dendrobium tea |
CN106615378A (en) * | 2016-12-26 | 2017-05-10 | 西林县大银子铁皮石斛种销农民专业合作社 | Heat-clearing and fluid-protecting healthcare tea packet |
-
2000
- 2000-09-26 CN CN 00125403 patent/CN1345596A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1311855C (en) * | 2004-07-12 | 2007-04-25 | 浙江省中药研究所 | Officinal Dendrobium stem capsule and preparing method |
CN101695328B (en) * | 2009-10-27 | 2012-11-14 | 白汉玉 | Dendrobium tea |
CN102132759A (en) * | 2011-04-27 | 2011-07-27 | 贾晋科 | Bagged winter health care tea |
CN106615378A (en) * | 2016-12-26 | 2017-05-10 | 西林县大银子铁皮石斛种销农民专业合作社 | Heat-clearing and fluid-protecting healthcare tea packet |
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