CN1320905C - Inflammation-resisting pain-stopping preparation - Google Patents
Inflammation-resisting pain-stopping preparation Download PDFInfo
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- CN1320905C CN1320905C CNB2005100466943A CN200510046694A CN1320905C CN 1320905 C CN1320905 C CN 1320905C CN B2005100466943 A CNB2005100466943 A CN B2005100466943A CN 200510046694 A CN200510046694 A CN 200510046694A CN 1320905 C CN1320905 C CN 1320905C
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Abstract
The present invention relates to an inflammation resisting and pain relieving preparation for treating joints, sinew membranes, muscles, nerves, etc., which solves the problems in the treatment of the existing inflammation resisting and pain relieving medicines of side effect, easy disease generation and easy serious injuries. The present invention is prepared from the following raw materials by the weight ratio: 1 portion of shortstalk monkshood root, 0.3 to 1 portion of nux vomica, 0.2 to 1 portion of henbane seed and 0.5 to 5 portions of licorice. The oral preparation uses the shortstalk monkshood root and other medicines and achieves much better inflammation resisting and pain relieving curative effect. The preparation is reasonably compounded, and thus, the preparation can perform favorable coordination functions in curative effect; the present invention draws strong points to offset weak points, and the medicines act on each other to enhance medicinal effect and are combined to jointly perform functions. The medicines can also reduce respective specific toxicity and bias properties, and thus, the preparation realizes the beneficial effects of activating blood circulation, dissipating stasis, soothing veins and arteries, relieving pain, expelling wind, eliminating impediment and realizing strong and fast pain suppressing functions and small toxic and side effect.
Description
Technical field
The present invention is a kind of Chinese medicine preparation, particularly a kind of a kind of inflammation-resisting pain-stopping preparation for the treatment of joint, fascia, muscle, nerve etc.
Background technology
Organ that human body is dissimilar and system under the unified adjusting and control of nervus centralis, interact, and condition each other, and coordinate mutually, finish unified physiological function activity.
And anti-inflammatory and antalgic be the treatment disease important step, treating antiinflammatory and analgesic medicine at present has side effect, easily cause pathogenic, seriously disable.Though as opioid drug such as morphine, tramadol, bucinnazine etc. very strong analgesic activity is arranged, to the inhibitory action and the toleration of respiratory center, particularly often use can cause addiction, and has limited its extensive use clinically; Amcinonide such as dexamethasone, Triamcinolone Acetonide etc. commonly used.Oral administration, intravenous injection, nerve block, caudal block, therapies such as dura mater place retardance are because of individual diversity XOR misapplication can cause following untoward reaction: a, class hypercorticalismus disease; Entad fat, circle month face, easy infection and mental excitation.Diabetes, osteoporosis due to b, sugar, the protein metabolism disorder, amyotrophy.C, digestive tract complication cause gastric perforation and hemorrhage etc.Think is by the not acceptant medicine of people.In addition, several special injecting methods, complicated operation, the layman must not operate, and expense is higher, so also be difficult for being accepted by the people.And existing Chinese medicine preparation YUANHU ZHITONG PIAN, onset is slow, and action time is short, only mild pain is had mitigation, does not satisfy the needs of people's anti-inflammatory and antalgic.So in treatment lysis, it is particularly important to improve central nervous system function effectively.
Summary of the invention
The objective of the invention is to, solve above-mentioned existing problem, a kind of strong drug action is provided, effect is lasting, and curative effect is fast, and antiinflammatory does not have hormone, and the not inflammation-resisting pain-stopping preparation of addiction eases pain.
The present invention presses column weight amount proportioning and makes:
Used spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Strychni, Semen Hyoscyami, Radix Glycyrrhizae are according to 1: 0.3～1: 0.2～1: 0.5～5 preparations;
The general pharmacological action of each medicine and good effect of the present invention are:
Its main component of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is an aconitine, hypaconitine; Analgesic activity is strong, and its intensity is 43.7 times of morphine, and analgesic activity time length is 12～36 hours, and evidence is the analgesics of addiction not.But toxicity is 300 times of morphine, needs other medicine to alleviate, and poisons the excited symptom of parasympathetic nervous to occur, is the central analgesics, and analgesic mechanism and maincenter norepinephrine are closely related.It is to suppress excitor nerve dried conduction or nerve trunk and completely loses excitement and conducting power.Significant antiinflammatory action is arranged, and its antiinflammatory action mechanism have the pass with the prostatitis of maincenter and scorching kitchen range, can directly act on Skeletal Muscle Cell and nervous tissue's cell.Select Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) for use, kind energy expelling wind and removing dampness, dispelling cold by warming the meridian, promoting blood circulation and stopping pain; The treating the poisonous disease with poisonous drugs of using in this preparation is monarch.
The main component of Semen Strychni is strychnine, strychnine; Strychnine has analgesic activity, but is weaker than dolantin, and the persistent period is longer 4 times than dolantin.Strychnine all has excitation to whole central nervous system, especially spinal cord is had the selectivity of height, significant microcirculation improvement.Poisonnut hardship, cold; Be very toxic product, can search the rheumatism that muscles and bones is gone into joint because of it is kind, open meridians, the power that reaches arthralgia relief thoroughly is quite strong, and real is the dispelling the wind and dampness pathogens insensitive impediment, the good merchantable brand of contracture pain paralysis numbness, and collaborative Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) treating the poisonous disease with poisonous drugs also helps the through focus of medicine, and compatibility is a minister.
The Main Ingredients and Appearance of Semen Hyoscyami is atropine, scopolamine; Alkaloid in the Semen Hyoscyami is the atropine Alkaloid, is typical M cholinergic receptor-blocking agent, has the general action of such medicine; As suppress glandular secretion, and mydriasis, loose visceral smooth muscle is removed vagus nerve to action of the heart, blood vessel dilating, microcirculation improvement, excited maincenter, protection cell membrane and lysosome effect also have antalgic and sedative and improve macrophage phagocytic function.Select its treating the poisonous disease with poisonous drugs for use, and effectively the antagonism Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) strengthens the effect of pain relieving relieving convulsion to cardiovascular and neural toxicity, can also blood vessel dilating and microcirculation improvement.Perfect Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) with malicious detoxicating functions, compatibility is assistant.
The Main Ingredients and Appearance of Radix Glycyrrhizae is glycyrrhizin acid, glycyrrhizic acid, enoxolone, and antiinflammatory, antiviral, arrhythmia, antiallergic, analgesia, spasmolytic and special Detoxication are arranged.In this preparation, select the heat that Radix Glycyrrhizae can above-mentioned clearly all medicines for use, can separate the poison of all medicines again, relax the property of medicine, strengthen the effect of pain relieving eliminating impediment; And strengthening vital QI to eliminate pathogenic factors, compatibility is for making.
This preparation cures mainly anti-inflammatory and antalgics such as joint, fascia, muscle, nerve.As rheumatism, rheumatoid arthritis, the osteoarthrosis synovitis, senile osteoarthritis, prolapse of lumbar intervertebral disc disease, scapulohumeral periarthritis etc. are traumatic, the treatment of the inflammatory of strain property neck shoulder back extremity.
Monarch, minister, help, make, treating the poisonous disease with poisonous drugs detoxifies with poison; Each its effect, and carry out rational proportion makes it produce good coordinative role on curative effect, learns from other's strong points to offset one's weaknesses, and interacts, and the enhancing drug effect is closed and shared; Can reduce separately peculiar toxicity and bias again, thereby realize blood circulation promoting and blood stasis dispelling, the inducing menstruation to relieve menalgia eliminating impediment that dispels the wind, analgesic activity is strong and fast, the beneficial effect that toxic and side effects is little.Use Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) in this oral formulations and cooperate other medicines, obtained easy unimaginable anti-inflammatory and antalgic curative effect; Applied range, the medicine source is extensive, and price is low, and production technology is simple, and investment cost is low.
The typical case of its treatment:
1, patient, woman 71 years old; The right side knee joint, old osteoarthritis 3 years is surplus, through how tame hospital, the several different methods treatment, the state of an illness increases the weight of; Can not fully take care of oneself in indoor life nearly half a year.The capsule of oral inflammation-resisting pain-stopping preparation of the present invention, every day 2 times, each 1,400 milligrams every, taking medicine after meal.Symptom obviously alleviates after 3 days, and walking along the street downstairs is 1 kilometer voluntarily.After taking medicine one month, the rehabilitation drug withdrawal, life is taken care of oneself fully.
2, patient, woman 42 years old, peasant; Sprain one's back accidentally in work, can not walk, emergency diagnosis is an acute lumbar muscle sprain, waist 3, the little joint disorders of waist 4 intervertebrals.Oral YAOTONGNING, paracetamol ﹠ codeine, external safflower oil aerosol are handled, and pain symptom still loses alleviation after 2 days, can not stand up, can only lie supine bed on simple activities.The capsule of oral inflammation-resisting pain-stopping preparation of the present invention, every day 2 times, each 1,400 milligrams every, taking medicine after meal.Pain symptom obviously alleviates after 2 days, and simple work is done in the walking of leaving the bed, rehabilitation drug withdrawal after several days.
3, patient, woman 45 years old is sought medical advice by the people hospital of injuring; Head, extremity, back part have 2 * 2mm, 2 * 3cm lump 15 places that differ in size, lump congestion and edema, no blood stasis.General aching can not be lain up.The capsule of oral inflammation-resisting pain-stopping preparation of the present invention, every day 2 times, each 1,400 milligrams every, taking medicine after meal.Take medicine and to lie up in back 2 hours.Took medicine 3 days, swelling all disappears, drug withdrawal.
The specific embodiment
The material of at first getting it filled is done following processing:
1, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is cleaned the back water-boiling method and handle, it is standby that 100 purpose medicated powder are pulverized in the oven dry back;
2, the pot of Semen Strychni being put into 200～240 ℃ is fried taking-up in 5～10 minutes, and it is standby to be crushed to 100 purpose medicated powder after the mechanical epilation;
3, it is standby Semen Hyoscyami to be crushed to 80 purpose medicated powder;
4, it is standby Radix Glycyrrhizae to be crushed to 100 purpose medicated powder;
Used spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Strychni, Semen Hyoscyami, Radix Glycyrrhizae are according to 1: 0.3～1: 0.2～1: 0.5～5 preparations;
Example 1 is got the spice of handling well and is taken by weighing by the proportioning in the prescription of the present invention, and Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, Semen Strychni 30mg, Semen Hyoscyami 20mg, Radix Glycyrrhizae 50mg put into container, stir, and in incapsulating then, every capsules 0.4g that packs into.
Example 2 is got spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, the Semen Strychni 60mg, Semen Hyoscyami 50mg, the Radix Glycyrrhizae 100mg that handle well and is put into container, stirs, and in incapsulating then, every capsules 0.4g that packs into.In addition, can also make sugar coated tablet, weight is the 0.2g coated tablet.
Example 3 is got spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, the Semen Strychni 80mg, Semen Hyoscyami 80mg, the Radix Glycyrrhizae 400mg that handle well and is put into container, stirs, and in incapsulating then, every capsules 0.4g that packs into.In addition, can also make sugar coated tablet, weight is the 0.2g coated tablet.
Example 4 is got spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, the Semen Strychni 100mg, Semen Hyoscyami 100mg, the Radix Glycyrrhizae 500mg that handle well and is put into container, stirs, and in incapsulating then, every capsules 0.4g that packs into.In addition, can also make sugar coated tablet, weight is the 0.2g coated tablet.
Claims (6)
1, a kind of inflammation-resisting pain-stopping preparation is characterized in that, the present invention presses column weight amount proportioning and makes: used spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Strychni, Semen Hyoscyami, Radix Glycyrrhizae are according to 1: 0.3～1: 0.2～1: 0.5～5 preparations.
2, according to the said a kind of inflammation-resisting pain-stopping preparation of claim 1, it is characterized in that, getting the spice of handling well takes by weighing by the proportioning in the prescription of the present invention, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, Semen Strychni 30mg, Semen Hyoscyami 20mg, Radix Glycyrrhizae 50mg put into container, stir, in incapsulating then, every capsules 0.4g that packs into.
3, according to the said a kind of inflammation-resisting pain-stopping preparation of claim 1, it is characterized in that, get spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, the Semen Strychni 60mg, Semen Hyoscyami 50mg, the Radix Glycyrrhizae 100mg that handle well and put into container, stir, in incapsulating then, every capsules 0.4g that packs into.
4, according to the said a kind of inflammation-resisting pain-stopping preparation of claim 1, it is characterized in that, get spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, the Semen Strychni 80mg, Semen Hyoscyami 80mg, the Radix Glycyrrhizae 400mg that handle well and put into container, stir, in incapsulating then, every capsules 0.4g that packs into.
5, according to the said a kind of inflammation-resisting pain-stopping preparation of claim 1, it is characterized in that, get spice Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 100mg, the Semen Strychni 100mg, Semen Hyoscyami 100mg, the Radix Glycyrrhizae 500mg that handle well and put into container, stir, in incapsulating then, every capsules 0.4g that packs into.
According to the said a kind of inflammation-resisting pain-stopping preparation of claim 1, it is characterized in that 6, can also make sugar coated tablet, weight is the 0.2g coated tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100466943A CN1320905C (en) | 2005-06-14 | 2005-06-14 | Inflammation-resisting pain-stopping preparation |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100466943A CN1320905C (en) | 2005-06-14 | 2005-06-14 | Inflammation-resisting pain-stopping preparation |
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| CN1720967A CN1720967A (en) | 2006-01-18 |
| CN1320905C true CN1320905C (en) | 2007-06-13 |
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| CNB2005100466943A Expired - Fee Related CN1320905C (en) | 2005-06-14 | 2005-06-14 | Inflammation-resisting pain-stopping preparation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361882B (en) * | 2008-09-04 | 2011-01-12 | 吴理靖 | Chinese medicine formulation for treating rheumatic osteoarthropathy |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114288338A (en) * | 2022-02-25 | 2022-04-08 | 冯学君 | Yuzhuo anti-inflammatory analgesic capsule |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569099A (en) * | 2003-10-09 | 2005-01-26 | 王向云 | rheumatism treating Chinese medicinal paste |
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2005
- 2005-06-14 CN CNB2005100466943A patent/CN1320905C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569099A (en) * | 2003-10-09 | 2005-01-26 | 王向云 | rheumatism treating Chinese medicinal paste |
Non-Patent Citations (1)
| Title |
|---|
| 中药治疗癌症疼痛的临床应用概况 吴大真，王凤岐，张丽，李健新，中国中医基础医学杂志，第4卷第04期 1998 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361882B (en) * | 2008-09-04 | 2011-01-12 | 吴理靖 | Chinese medicine formulation for treating rheumatic osteoarthropathy |
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| Publication number | Publication date |
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| CN1720967A (en) | 2006-01-18 |
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