CN101926957A - Medicinal composition for treating arthralgia syndrome and preparation method thereof - Google Patents
Medicinal composition for treating arthralgia syndrome and preparation method thereof Download PDFInfo
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- CN101926957A CN101926957A CN2009100869228A CN200910086922A CN101926957A CN 101926957 A CN101926957 A CN 101926957A CN 2009100869228 A CN2009100869228 A CN 2009100869228A CN 200910086922 A CN200910086922 A CN 200910086922A CN 101926957 A CN101926957 A CN 101926957A
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Abstract
The invention discloses a medicinal composition for treating arthralgia syndrome and a preparation method thereof. The medicinal composition consists of an A group of raw material medicaments and a B group of raw material medicaments, wherein the A group consists of toad, garden balsam stem, nux vomica, frankincense, myrrh, cochinchina momordica seed kernel, raw common monkshood mother root, raw kusnezoff monkshood root, raw arisaema, jamestownweed seeds, asarum, common burreed rhizome, zedoary, safflower, peach kernel, eucommia bark, teasel, Chinese taxillus twig, incised notopterygium rhizome, pubescent angelica root, Chinese clematis and medicinal cyathula root; and the B group consists of fried pangolin scales, dragon's blood, clove, grassleaf sweelflag rhizome, angelica dahurica, garden balsam, sanchi, ephedra herb, gansui root, castor seeds, camphor and menthol. The medicinal composition has the effects of expelling wind, removing dampness and clearing cold, dissolving stasis and activating blood, reducing swelling and easing pain, and nourishing muscle and strengthening tendon, and has remarkable effect of treating cervical spondylosis, scapulohumeral periarthritis, rheumatic arthritis, hyperosteogeny, protrusion of lumbar vertebral disc, cold and numb pains of muscle and joint and other diseases.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of arthromyodynia and preparation method thereof.
Background technology
Arthromyodynia is not a kind of independently disease, but one group of general name that can cause spinal column, soft tissue and the neuropathy of neck, shoulder, waist and leg portion pain.Arthromyodynia is because of wind, cold, the wet three heresies invasion and attack human body that combines, and resistance numbness meridians cause that the QI and blood long journey is smooth and fall ill, and is feature with clinical manifestations such as limbs joint pain, numbness, swelling, stiff, distortion, limitation of activity.Present Drug therapy is many with auxiliary therapy, because arthromyodynia easily produces patient's joint deformity, redness, pain and tests and bear, therefore the auxiliary therapy time is long, and cure the symptoms, not the disease, increased patient's burden in life misery on the health, have a strong impact on people's life and health, so the development of novel drugs is imperative.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition for the treatment of arthromyodynia; Another object of the present invention is to provide this preparation of drug combination method and purposes.
The crude drug of pharmaceutical composition of the present invention consists of:
The A group:
Bufo siccus 500-1500 weight portion Herba speranskiae tuberculatae 100-200 weight portion Semen Strychni 50-150 weight portion
Olibanum 30-90 weight portion Myrrha 30-90 weight portion Semen Momordicae 20-60 weight portion
Radix Aconiti 20-60 weight portion Radix Aconiti Kusnezoffii 20-60 weight portion Rhizoma Arisaematis 20-60 weight portion
Semen daturae 20-60 weight portion Herba Asari 20-60 weight portion rhizoma sparganic 25-75 weight portion
Rhizoma Curcumae 25-75 weight portion Flos Carthami 25-75 weight portion Semen Persicae 25-75 weight portion
Cortex Eucommiae 25-75 weight portion Radix Dipsaci 25-75 weight portion Herba Taxilli 25-75 weight portion
Rhizoma Et Radix Notopterygii 25-75 weight portion Radix Angelicae Pubescentis 25-75 weight portion Radix Clematidis 25-75 weight portion
Radix Cyathulae 25-75 weight portion;
The B group:
Stir-baked SQUAMA MANITIS 25-75 weight portion Sanguis Draxonis 15-45 weight portion Flos Caryophylli 15-45 weight portion
Rhizoma Acori Graminei 25-75 weight portion Radix Angelicae Dahuricae 25-75 weight portion Semen Impatientis 15-45 weight portion
Radix Notoginseng 25-75 weight portion Herba Ephedrae 25-75 weight portion Radix Kansui 25-75 weight portion
Semen Ricini 15-45 weight portion Camphora 15-45 weight portion Mentholum 15-45 weight portion.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
The A group:
Bufo siccus 1000 weight portion Herba speranskiae tuberculataes 150 weight portion Semen Strychni 100 weight portions
Olibanum 60 weight portion Myrrhas 60 weight portion Semen Momordicaes 40 weight portions
Radix Aconiti 40 weight portion Radix Aconiti Kusnezoffii 40 weight portion Rhizoma Arisaematis 40 weight portions
Semen daturae 40 weight portion Herba Asaris 40 weight portion rhizoma sparganic 50 weight portions
Rhizoma Curcumae 50 weight portion Flos Carthamis 50 weight portion Semen Persicaes 50 weight portions
The Cortex Eucommiae 50 weight portion Radix Dipsacis 50 weight portion Herba Taxillis 50 weight portions
Rhizoma Et Radix Notopterygii 50 weight portion Radix Angelicae Pubescentiss 50 weight portion Radix Clematidis 50 weight portions
Radix Cyathulae 50 weight portions;
The B group:
Stir-baked SQUAMA MANITIS 50 weight portion Sanguis Draxonis 30 weight portion Flos Caryophyllis 30 weight portions
The Rhizoma Acori Graminei 50 weight portion Radixs Angelicae Dahuricae 50 weight portion Semen Impatientis 30 weight portions
Radix Notoginseng 50 weight portion Herba Ephedraes 50 weight portion Radix Kansuis 50 weight portions
Semen Ricini 30 weight portion Camphoras 30 weight portion Mentholums 30 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
The A group:
Bufo siccus 1400 weight portion Herba speranskiae tuberculataes 110 weight portion Semen Strychni 140 weight portions
Olibanum 40 weight portion Myrrhas 80 weight portion Semen Momordicaes 30 weight portions
Radix Aconiti 50 weight portion Radix Aconiti Kusnezoffii 30 weight portion Rhizoma Arisaematis 50 weight portions
Semen daturae 30 weight portion Herba Asaris 50 weight portion rhizoma sparganic 30 weight portions
Rhizoma Curcumae 70 weight portion Flos Carthamis 30 weight portion Semen Persicaes 70 weight portions
The Cortex Eucommiae 30 weight portion Radix Dipsacis 70 weight portion Herba Taxillis 30 weight portions
Rhizoma Et Radix Notopterygii 70 weight portion Radix Angelicae Pubescentiss 30 weight portion Radix Clematidis 70 weight portions
Radix Cyathulae 30 weight portions;
The B group:
Stir-baked SQUAMA MANITIS 70 weight portion Sanguis Draxonis 20 weight portion Flos Caryophyllis 40 weight portions
The Rhizoma Acori Graminei 30 weight portion Radixs Angelicae Dahuricae 70 weight portion Semen Impatientis 20 weight portions
Radix Notoginseng 70 weight portion Herba Ephedraes 30 weight portion Radix Kansuis 70 weight portions
Semen Ricini 20 weight portion Camphoras 40 weight portion Mentholums 20 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
The A group:
Bufo siccus 600 weight portion Herba speranskiae tuberculataes 190 weight portion Semen Strychni 60 weight portions
Olibanum 80 weight portion Myrrhas 40 weight portion Semen Momordicaes 50 weight portions
Radix Aconiti 30 weight portion Radix Aconiti Kusnezoffii 50 weight portion Rhizoma Arisaematis 30 weight portions
Semen daturae 50 weight portion Herba Asaris 30 weight portion rhizoma sparganic 70 weight portions
Rhizoma Curcumae 30 weight portion Flos Carthamis 70 weight portion Semen Persicaes 30 weight portions
The Cortex Eucommiae 70 weight portion Radix Dipsacis 30 weight portion Herba Taxillis 70 weight portions
Rhizoma Et Radix Notopterygii 30 weight portion Radix Angelicae Pubescentiss 70 weight portion Radix Clematidis 30 weight portions
Radix Cyathulae 70 weight portions;
The B group:
Stir-baked SQUAMA MANITIS 30 weight portion Sanguis Draxonis 40 weight portion Flos Caryophyllis 20 weight portions
The Rhizoma Acori Graminei 70 weight portion Radixs Angelicae Dahuricae 30 weight portion Semen Impatientis 40 weight portions
Radix Notoginseng 30 weight portion Herba Ephedraes 70 weight portion Radix Kansuis 30 weight portions
Semen Ricini 40 weight portion Camphoras 20 weight portion Mentholums 40 weight portions.
Preparation of drug combination method of the present invention is:
The preparation technology of black plaster:
Be equipped with medicine: A is organized drug immersion 5-7 days with Oleum sesami 2000-4000 weight portion; B is organized medicine, and to be ground into thin medicated powder standby;
Explosive: the heating of soaked A group medicine is decocted, be dark brown to the medicine outside, inner sallow being advisable removed medicinal residues and filtered, and promptly gets medicine oil;
Oil refining: with the heating of medicine oil, oil smoke is that light cyan gradually becomes black dense smoke, becomes white dense smoke by black smoke, and oil refining is finished;
Pilling and pasting: the medicine oil that will refine is cold slightly from fire, when treating oily temperature drop to 280-300 ℃, add Plumbum preparatium 1000-2000 weight portion in the oil inchmeal, ceaselessly stir along a direction simultaneously, prevent that Plumbum preparatium from sinking to the bottom of a pan, this moment, medicine oil can violently seethe with excitement, and the surface has a large amount of foams and zest dense smoke to produce, after medicine oil and Plumbum preparatium reaction finish, get the liquid plaster;
Old tender test: the liquid plaster that takes a morsel splashes in the cold water, treats that the liquid plaster solidifies the back and takes out, and as sticking hands, tearing hands has silk, and the expression ointment is tender excessively, should continue to decoct, and is promptly disconnected as if what tear, then for old excessively, should endure with Oleum sesami, until old tender suitable again;
Releasing fire-toxin: will refine good plaster, and pour at leisure and soak in the water, and change water constantly, and after the cooling, change water every day 1 time, soak 5-7 days;
The stand plaster: the plaster water proof heating behind the detoxification is dissolved, add the B that has got ready and organize thin medicated powder, add far infrared ceramic powder 20-60 weight portion, the infiltration of azone 5-15 parts by volume again, stir, keep 70-90 ℃ temperature, spread out in plaster and stick, after cooling, cover lining paper, seal in the plastic bag of packing into, put the moon and dry the preservation of dry place, promptly get black plaster.
The preparation technology of black plaster is preferably:
Be equipped with medicine: A was organized drug immersion 6 days with Oleum sesami 3000 weight portions; B is organized medicine, and to be ground into thin medicated powder standby;
Explosive: the heating of soaked A group medicine is decocted, be dark brown to the medicine outside, inner sallow being advisable removed medicinal residues and filtered, and promptly gets medicine oil;
Oil refining: with the heating of medicine oil, oil smoke is that light cyan gradually becomes black dense smoke, becomes white dense smoke by black smoke, and oil refining is finished;
Pilling and pasting: the medicine oil that will refine is cold slightly from fire, when treating oily temperature drop to 280-300 ℃, add Plumbum preparatium 1500 weight portions in the oil inchmeal, ceaselessly stir along a direction simultaneously, prevent that Plumbum preparatium from sinking to the bottom of a pan, this moment, medicine oil can violently seethe with excitement, and the surface has a large amount of foams and zest dense smoke to produce, after medicine oil and Plumbum preparatium reaction finish, get the liquid plaster;
Old tender test: the liquid plaster that takes a morsel splashes in the cold water, treats that the liquid plaster solidifies the back and takes out, and as sticking hands, tearing hands has silk, and the expression ointment is tender excessively, should continue to decoct, and is promptly disconnected as if what tear, then for old excessively, should endure with Oleum sesami, until old tender suitable again;
Releasing fire-toxin: will refine good plaster, and pour at leisure and soak in the water, and change water constantly, and after the cooling, change water every day 1 time, soak 6 days;
The stand plaster: the plaster water proof heating behind the detoxification is dissolved, add the B that has got ready and organize thin medicated powder, add far infrared ceramic powder 40 weight portions, the infiltration of azone 10 parts by volume again, stir, keep 70-90 ℃ temperature, spread out in plaster and stick, after cooling, cover lining paper, seal in the plastic bag of packing into, put the moon and dry the preservation of dry place, promptly get black plaster.
The preparation technology of Colophonium plaster:
Prepare the dried medicated powder that soaks: B is organized medicine, and to be ground into thin medicated powder standby; Get Bufo siccus, Olibanum, Myrrha in the A group, friedly in 500-1500 parts by volume Oleum sesami be dark brown, filter, become breast not have Bufo siccus oil to the outside, standby; Again all the other 19 herbal medicines in the A group are decocted with water extraction, filters three times, filtrate concentrates, and adds B and organizes thin medicated powder, stir evenly, dry, pulverize, 120 mesh sieves standby, promptly get the dried medicated powder that soaks;
Preparation Colophonium plaster: breast is not had Bufo siccus oil, Colophonium 5500-6000 weight portion, Cera Flava 700-800 weight portion mixing heat fused, along with oily temperature increases, begin to occur black smoke in the pot, the stirring that do not stop this moment, when black dense smoke became white dense smoke by Zhejiang, the sign lubricate was about to be boiled into, and does old tender test turning off stove, when temperature is reduced to 60-80 ℃, add the dried medicated powder that soaks again, far infrared ceramic powder 60-100 weight portion, azone 10-30 parts by volume is mixed thoroughly, promptly gets the Colophonium plaster, spread out in plaster and stick, cover lining paper, seal in the plastic bag of packing into, re-use after putting into the freezing 24-72 of refrigerator hour releasing fire-toxin.
The preparation technology of Colophonium plaster is preferably:
Prepare the dried medicated powder that soaks: B is organized medicine, and to be ground into thin medicated powder standby; Get Bufo siccus, Olibanum, Myrrha in the A group, friedly in 1000 parts by volume Oleum sesami be dark brown, filter, become breast not have Bufo siccus oil to the outside, standby; Again all the other 19 herbal medicines in the A group are decocted with water extraction, filters three times, filtrate concentrates, and adds B and organizes thin medicated powder, stir evenly, dry, pulverize, 120 mesh sieves standby, promptly get the dried medicated powder that soaks;
Preparation Colophonium plaster: breast is not had Bufo siccus oil, Colophonium 5800 weight portions, Cera Flava 750 weight portion mixing heat fused, along with oily temperature increases, begin to occur black smoke in the pot, the stirring that do not stop this moment, when black dense smoke became white dense smoke by Zhejiang, the sign lubricate was about to be boiled into, and does old tender test turning off stove, when temperature is reduced to 70 ℃, add the dried medicated powder that soaks again, far infrared ceramic powder 80 weight portions, azone 20 parts by volume are mixed thoroughly, promptly get the Colophonium plaster, spread out in plaster and stick, cover lining paper, seal in the plastic bag of packing into, put into refrigerator and re-used behind the releasing fire-toxin in freezing 48 hours.
Pharmaceutical composition of the present invention adds pharmaceutically conventional adjuvant according to common process and makes in clinical acceptable powder, liniment, emplastrum, red unguentum, black unguentum, spray, ointment, ointment or the medicated wine any one.
Pharmaceutical composition of the present invention has the effect of expelling wind and removing dampness cold expelling, eliminating blood stasis and promoting blood circulation, reducing swelling and alleviating pain, muscle-nourishing bone-strengthening, has remarkable effect for diseases such as treatment cervical spondylosis, scapulohumeral periarthritis, rheumatic arthritis, hyperosteogeny, prolapse of lumbar intervertebral disc, the cold numb pains of muscle joint acid.
The pass of above-mentioned weight portion and parts by volume is the relation of gram and milliliter, g/ml.
Following experimental example is used to further specify but is not limited to the present invention:
From medicine composite for curing patient 879 people's clinical observations of the present invention in year November in April, 2005 to 2007:
One, physical data
879 patients all are the outpatient, wherein male 425 people, and women 454 people, the oldest 87 years old, minimum 16 years old, curative effect was for details see attached table.
Medicine composite for curing 879 routine patient's clinical efficacy statistical tables of the present invention
| Classification | Case | Recovery from illness | Produce effects | Effectively | Invalid | Effective percentage |
| Rheumatic arthritis | 347 | 102 | 180 | 62 | 3 | 99％ |
| Cervical spondylosis | 48 | 24 | 10 | 11 | 3 | 94％ |
| Scapulohumeral periarthritis | 265 | 98 | 87 | 69 | 11 | 96％ |
| Hyperosteogeny | 84 | 20 | 38 | 20 | 6 | 93％ |
| Prolapse of lumbar intervertebral disc | 39 | 2 | 25 | 7 | 5 | 87％ |
| Ossa articularia carnic acid fiber crops are cold | 96 | 62 | 22 | 12 | 0 | 100％ |
| Add up to | 879 | 308 | 362 | 181 | 28 | 97％ |
Two, diagnostic criteria:
Meet traditional Chinese medical science arthromyodynia, neck-shoulder pain, lumbago and leg pain diagnostic criteria.
Three, criterion of therapeutical effect:
Recovery from illness: clinical symptom disappearance, do not see recurrence in 1 year.
Produce effects: clinical symptoms disappears substantially;
Effectively: clinical symptoms control;
Invalid: clinical symptoms is not controlled or is increased the weight of.
Four, Therapeutic Method:
Using method:
The external application affected part becomes corresponding acupoints, and 2-3 day is changed once, and five subsides are a course of treatment.
Points for attention:
During the medication, can cooperate acupuncture treatment, take medicine, injection waits some other method Synergistic treatment to improve curative effect.Stick behind the plaster as drug eruption occurs, light disease is thrown off ointment can die away, and serious symptom can be wiped outward with the antiallergic ointment, treats to stick after drug eruption disappears again.
Five, detailed case:
Case 1: Wei, the man, 48 years old, the workman, dizziness and nausea 7 days goes examination in hospital X line cervical curvature to become straight, and hyperosteogeny is arranged, and on August 4th, 2007 came me to go to a doctor, and it is invalid that readme is beaten garter 5 days through doctor trained in Western medicine, deceives unguentum first quarter moon transference cure through using the present invention.
Case 2: Wang, man, 52 years old, peasant, it is month surplus that two knee joints swell and ache, and in anti-" 0 " 615 units of the People's Hospital's result of laboratory test, erythrocyte sedimentation rate 30m/ hour, is diagnosed as rheumatic arthritis, the clothes Chinese medicine and western medicine is invalid, and on April 8th, 2005 examined, and through using Colophonium unguentum external application of the present invention, just begins produce effects in two days.Swelling and ache slowly alleviates, and recovers normal after the logotype 5 times.
Case 3: Lee, the woman, work, the readme right side has a pain in the leg bitterly numb half a year, and L.4-L.5 outstanding through city miner hospital CT examination conclusion, through traction, it is invalid to massage.On October 5th, 2005 examined, and, wiped in Ashi point, Huantiao, gb 34, CHENGSHAN acupoint etc. logotype first quarter moon transference cure, not recurrence so far through using pharmaceutical composition liniment of the present invention.
Case 4: Lee, the woman, 63 years old, examined in May, 2004, and it is surplus to suffer from talalgia 2 years, and walking is stranded tests, and take the photograph sheet through the X line and show, the calcaneus hypertrophy, it is invalid to take multiple medicine, through using medicinal composition powders of the present invention, recovery from illness after 6 times, not recurrence in 3 years.
Case 5: Liu, the woman 82 years old, suffered from scapulohumeral periarthritis 2 years, the shoulder arm is stiff, can not wear the clothes and undress, and deceive unguentum external application with the present invention in October, 2007, and next day, the state of an illness alleviated, the shoulder arm can be movable on 3, can formally undress in 5th to wear the clothes, and two courses of treatment of logotype, symptom all disappears.
Case 6: Lu, the man, 46 years old, the workman, femoribus internus has the big tingle cold type of pain of muscle of palm 15 years, and winter, the pain increased, and in January, 2006, with Colophonium plaster outer plaster of the present invention, logotype three is pasted, and sour cold type of pain disappears, and continues again to paste transference cure with three.
Six, conclusion
This plaster prescription is a secret prescription handed down in the family from generation to generation, some modern science and technology have now been added, based on former side, add materials such as a certain amount of far infrared ceramic powder, azone synergism is arranged, not only improved the human-body biological film activity, the blood circulation of local organization and metabolism are improved and strengthened the permeability of medicine, made medicine and easily by human body skin barrier, infiltrate passages through which vital energy circulates, steadily bring into play drug effect enduringly.Pharmaceutical composition of the present invention is a principal agent with Bufo siccus, Semen Strychni, merit with activating collaterals and eliminating stagnation, subduing swelling and relieving pain, all make a living with Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Semen daturae, five kinds of medicines of Herba Asari, suddenly, the product of poison strengthen drug effect, with 27 flavor blood circulation promoting and blood stasis dispelling promoting QI to circulate and dispersing the agglomeration of the pathogens, the Chinese medicine of causing resuscitation with aromatic drugs combines again, it is the selected medicine of treatment " numbness " disease, all medicines are pieced together and are dredge the meridian passage, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the dispersing swelling and dissipating binds pain relieving, the effect of bone and muscle strengthening.Be effective good recipe of treatment neck, shoulder, waist, skelalgia, be worthy of popularization.
Following embodiment is used to further specify the present invention:
The specific embodiment
Embodiment 1: the preparation of black unguentum
The A group:
Bufo siccus 1000g Herba speranskiae tuberculatae 150g Semen Strychni 100g
Olibanum 60g Myrrha 60g Semen Momordicae 40g
Radix Aconiti 40g Radix Aconiti Kusnezoffii 40g Rhizoma Arisaematis 40g
Semen daturae 40g Herba Asari 40g rhizoma sparganic 50g
Rhizoma Curcumae 50g Flos Carthami 50g Semen Persicae 50g
Cortex Eucommiae 50g Radix Dipsaci 50g Herba Taxilli 50g
Rhizoma Et Radix Notopterygii 50g Radix Angelicae Pubescentis 50g Radix Clematidis 50g
Radix Cyathulae 50g;
The B group:
Stir-baked SQUAMA MANITIS 50g Sanguis Draxonis 30g Flos Caryophylli 30g
Rhizoma Acori Graminei 50g Radix Angelicae Dahuricae 50g Semen Impatientis 30g
Radix Notoginseng 50g Herba Ephedrae 50g Radix Kansui 50g
Semen Ricini 30g Camphora 30g Mentholum 30g;
Be equipped with medicine: A was organized drug immersion 6 days with Oleum sesami 3000g; B is organized medicine, and to be ground into thin medicated powder standby;
Explosive: the heating of soaked A group medicine is decocted, be dark brown to the medicine outside, inner sallow being advisable removed medicinal residues and filtered, and promptly gets medicine oil;
Oil refining: with the heating of medicine oil, oil smoke is that light cyan gradually becomes black dense smoke, becomes white dense smoke by black smoke, and oil refining is finished;
Pilling and pasting: the medicine oil that will refine is cold slightly from fire, when treating oily temperature drop to 280-300 ℃, add Plumbum preparatium 1500g in the oil inchmeal, ceaselessly stir along a direction simultaneously, prevent that Plumbum preparatium from sinking to the bottom of a pan, this moment, medicine oil can violently seethe with excitement, and the surface has a large amount of foams and zest dense smoke to produce, after medicine oil and Plumbum preparatium reaction finish, get the liquid plaster;
Old tender test: the liquid plaster that takes a morsel splashes in the cold water, treats that the liquid plaster solidifies the back and takes out, and as sticking hands, tearing hands has silk, and the expression ointment is tender excessively, should continue to decoct, and is promptly disconnected as if what tear, then for old excessively, should endure with Oleum sesami, until old tender suitable again;
Releasing fire-toxin: will refine good plaster, and pour at leisure and soak in the water, and change water constantly, and after the cooling, change water every day 1 time, soak 6 days;
The stand plaster: the plaster water proof heating behind the detoxification is dissolved, add the B that has got ready and organize thin medicated powder, add far infrared ceramic powder 40g, azone 10ml again and infiltrate, stir, keep 70-90 ℃ temperature, spread out in plaster and stick, after cooling, cover lining paper, seal in the plastic bag of packing into, put the moon and dry the preservation of dry place, promptly get black plaster.
The external application affected part becomes corresponding acupoints, and 2-3 day is changed once, and five subsides are a course of treatment.
Embodiment 2: the preparation of Colophonium unguentum
The A group:
Bufo siccus 1000g Herba speranskiae tuberculatae 150g Semen Strychni 100g
Olibanum 60g Myrrha 60g Semen Momordicae 40g
Radix Aconiti 40g Radix Aconiti Kusnezoffii 40g Rhizoma Arisaematis 40g
Semen daturae 40g Herba Asari 40g rhizoma sparganic 50g
Rhizoma Curcumae 50g Flos Carthami 50g Semen Persicae 50g
Cortex Eucommiae 50g Radix Dipsaci 50g Herba Taxilli 50g
Rhizoma Et Radix Notopterygii 50g Radix Angelicae Pubescentis 50g Radix Clematidis 50g
Radix Cyathulae 50g;
The B group:
Stir-baked SQUAMA MANITIS 50g Sanguis Draxonis 30g Flos Caryophylli 30g
Rhizoma Acori Graminei 50g Radix Angelicae Dahuricae 50g Semen Impatientis 30g
Radix Notoginseng 50g Herba Ephedrae 50g Radix Kansui 50g
Semen Ricini 30g Camphora 30g Mentholum 30g;
Prepare the dried medicated powder that soaks: B is organized medicine, and to be ground into thin medicated powder standby; Get Bufo siccus, Olibanum, Myrrha in the A group, friedly in 1000ml Oleum sesami be dark brown, filter, become breast not have Bufo siccus oil to the outside, standby; Again all the other 19 herbal medicines in the A group are decocted with water extraction, filters three times, filtrate concentrates, and adds B and organizes thin medicated powder, stir evenly, dry, pulverize, 120 mesh sieves standby, promptly get the dried medicated powder that soaks;
Preparation Colophonium plaster: breast is not had Bufo siccus oil, Colophonium 5800g, Cera Flava 750g mixing heat fused, along with oily temperature increases, begin to occur black smoke in the pot, the stirring that do not stop this moment, when black dense smoke became white dense smoke by Zhejiang, the sign lubricate was about to be boiled into, and does old tender test turning off stove, when temperature is reduced to 70 ℃, add the dried medicated powder that soaks again, far infrared ceramic powder 80g, azone 20ml mix thoroughly, promptly get the Colophonium plaster, spread out in plaster and stick, cover lining paper, seal in the plastic bag of packing into, put into refrigerator and re-used behind the releasing fire-toxin in freezing 48 hours.The external application affected part becomes corresponding acupoints, and 2-3 day is changed once, and five subsides are a course of treatment.
Embodiment 3: the preparation of powder
The A group:
Bufo siccus 1400g Herba speranskiae tuberculatae 110g Semen Strychni 140g
Olibanum 40g Myrrha 80g Semen Momordicae 30g
Radix Aconiti 50g Radix Aconiti Kusnezoffii 30g Rhizoma Arisaematis 50g
Semen daturae 30g Herba Asari 50g rhizoma sparganic 30g
Rhizoma Curcumae 70g Flos Carthami 30g Semen Persicae 70g
Cortex Eucommiae 30g Radix Dipsaci 70g Herba Taxilli 30g
Rhizoma Et Radix Notopterygii 70g Radix Angelicae Pubescentis 30g Radix Clematidis 70g
Radix Cyathulae 30g;
The B group:
Stir-baked SQUAMA MANITIS 70g Sanguis Draxonis 20g Flos Caryophylli 40g
Rhizoma Acori Graminei 30g Radix Angelicae Dahuricae 70g Semen Impatientis 20g
Radix Notoginseng 70g Herba Ephedrae 30g Radix Kansui 70g
Semen Ricini 20g Camphora 40g Mentholum 20g.
Get the above-mentioned raw materials medicine, make powder according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 4: the preparation of spray
The A group:
Bufo siccus 600g Herba speranskiae tuberculatae 190g Semen Strychni 60g
Olibanum 80g Myrrha 40g Semen Momordicae 50g
Radix Aconiti 30g Radix Aconiti Kusnezoffii 50g Rhizoma Arisaematis 30g
Semen daturae 50g Herba Asari 30g rhizoma sparganic 70g
Rhizoma Curcumae 30g Flos Carthami 70g Semen Persicae 30g
Cortex Eucommiae 70g Radix Dipsaci 30g Herba Taxilli 70g
Rhizoma Et Radix Notopterygii 30g Radix Angelicae Pubescentis 70g Radix Clematidis 30g
Radix Cyathulae 70g;
The B group:
Stir-baked SQUAMA MANITIS 30g Sanguis Draxonis 40g Flos Caryophylli 20g
Rhizoma Acori Graminei 70g Radix Angelicae Dahuricae 30g Semen Impatientis 40g
Radix Notoginseng 30g Herba Ephedrae 70g Radix Kansui 30g
Semen Ricini 40g Camphora 20g Mentholum 40g;
Get the above-mentioned raw materials medicine, make spray according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 5: the preparation of ointment
The A group:
Bufo siccus 1000g Herba speranskiae tuberculatae 150g Semen Strychni 100g
Olibanum 60g Myrrha 60g Semen Momordicae 40g
Radix Aconiti 40g Radix Aconiti Kusnezoffii 40g Rhizoma Arisaematis 40g
Semen daturae 40g Herba Asari 40g rhizoma sparganic 50g
Rhizoma Curcumae 50g Flos Carthami 50g Semen Persicae 50g
Cortex Eucommiae 50g Radix Dipsaci 50g Herba Taxilli 50g
Rhizoma Et Radix Notopterygii 50g Radix Angelicae Pubescentis 50g Radix Clematidis 50g
Radix Cyathulae 50g;
The B group:
Stir-baked SQUAMA MANITIS 50g Sanguis Draxonis 30g Flos Caryophylli 30g
Rhizoma Acori Graminei 50g Radix Angelicae Dahuricae 50g Semen Impatientis 30g
Radix Notoginseng 50g Herba Ephedrae 50g Radix Kansui 50g
Semen Ricini 30g Camphora 30g Mentholum 30g;
Get the above-mentioned raw materials medicine and make ointment according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 6: the preparation of ointment
The A group:
Bufo siccus 1400g Herba speranskiae tuberculatae 110g Semen Strychni 140g
Olibanum 40g Myrrha 80g Semen Momordicae 30g
Radix Aconiti 50g Radix Aconiti Kusnezoffii 30g Rhizoma Arisaematis 50g
Semen daturae 30g Herba Asari 50g rhizoma sparganic 30g
Rhizoma Curcumae 70g Flos Carthami 30g Semen Persicae 70g
Cortex Eucommiae 30g Radix Dipsaci 70g Herba Taxilli 30g
Rhizoma Et Radix Notopterygii 70g Radix Angelicae Pubescentis 30g Radix Clematidis 70g
Radix Cyathulae 30g;
The B group:
Stir-baked SQUAMA MANITIS 70g Sanguis Draxonis 20g Flos Caryophylli 40g
Rhizoma Acori Graminei 30g Radix Angelicae Dahuricae 70g Semen Impatientis 20g
Radix Notoginseng 70g Herba Ephedrae 30g Radix Kansui 70g
Semen Ricini 20g Camphora 40g Mentholum 20g;
Get the above-mentioned raw materials medicine and make ointment according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 7: the preparation of liniment
The A group:
Bufo siccus 600g Herba speranskiae tuberculatae 190g Semen Strychni 60g
Olibanum 80g Myrrha 40g Semen Momordicae 50g
Radix Aconiti 30g Radix Aconiti Kusnezoffii 50g Rhizoma Arisaematis 30g
Semen daturae 50g Herba Asari 30g rhizoma sparganic 70g
Rhizoma Curcumae 30g Flos Carthami 70g Semen Persicae 30g
Cortex Eucommiae 70g Radix Dipsaci 30g Herba Taxilli 70g
Rhizoma Et Radix Notopterygii 30g Radix Angelicae Pubescentis 70g Radix Clematidis 30g
Radix Cyathulae 70g;
The B group:
Stir-baked SQUAMA MANITIS 30g Sanguis Draxonis 40g Flos Caryophylli 20g
Rhizoma Acori Graminei 70g Radix Angelicae Dahuricae 30g Semen Impatientis 40g
Radix Notoginseng 30g Herba Ephedrae 70g Radix Kansui 30g
Semen Ricini 40g Camphora 20g Mentholum 40g;
The above-mentioned raw materials medicine is made liniment according to the conventional adjuvant that common process adds pharmaceutically.
Claims (10)
1. pharmaceutical composition for the treatment of arthromyodynia is characterized in that the crude drug of this pharmaceutical composition consists of:
The A group:
Bufo siccus 500-1500 weight portion Herba speranskiae tuberculatae 100-200 weight portion Semen Strychni 50-150 weight portion
Olibanum 30-90 weight portion Myrrha 30-90 weight portion Semen Momordicae 20-60 weight portion
Radix Aconiti 20-60 weight portion Radix Aconiti Kusnezoffii 20-60 weight portion Rhizoma Arisaematis 20-60 weight portion
Semen daturae 20-60 weight portion Herba Asari 20-60 weight portion rhizoma sparganic 25-75 weight portion
Rhizoma Curcumae 25-75 weight portion Flos Carthami 25-75 weight portion Semen Persicae 25-75 weight portion
Cortex Eucommiae 25-75 weight portion Radix Dipsaci 25-75 weight portion Herba Taxilli 25-75 weight portion
Rhizoma Et Radix Notopterygii 25-75 weight portion Radix Angelicae Pubescentis 25-75 weight portion Radix Clematidis 25-75 weight portion
Radix Cyathulae 25-75 weight portion;
The B group:
Stir-baked SQUAMA MANITIS 25-75 weight portion Sanguis Draxonis 15-45 weight portion Flos Caryophylli 15-45 weight portion
Rhizoma Acori Graminei 25-75 weight portion Radix Angelicae Dahuricae 25-75 weight portion Semen Impatientis 15-45 weight portion
Radix Notoginseng 25-75 weight portion Herba Ephedrae 25-75 weight portion Radix Kansui 25-75 weight portion
Semen Ricini 15-45 weight portion Camphora 15-45 weight portion Mentholum 15-45 weight portion.
2. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
The A group:
Bufo siccus 1000 weight portion Herba speranskiae tuberculataes 150 weight portion Semen Strychni 100 weight portions
Olibanum 60 weight portion Myrrhas 60 weight portion Semen Momordicaes 40 weight portions
Radix Aconiti 40 weight portion Radix Aconiti Kusnezoffii 40 weight portion Rhizoma Arisaematis 40 weight portions
Semen daturae 40 weight portion Herba Asaris 40 weight portion rhizoma sparganic 50 weight portions
Rhizoma Curcumae 50 weight portion Flos Carthamis 50 weight portion Semen Persicaes 50 weight portions
The Cortex Eucommiae 50 weight portion Radix Dipsacis 50 weight portion Herba Taxillis 50 weight portions
Rhizoma Et Radix Notopterygii 50 weight portion Radix Angelicae Pubescentiss 50 weight portion Radix Clematidis 50 weight portions
Radix Cyathulae 50 weight portions;
The B group:
Stir-baked SQUAMA MANITIS 50 weight portion Sanguis Draxonis 30 weight portion Flos Caryophyllis 30 weight portions
The Rhizoma Acori Graminei 50 weight portion Radixs Angelicae Dahuricae 50 weight portion Semen Impatientis 30 weight portions
Radix Notoginseng 50 weight portion Herba Ephedraes 50 weight portion Radix Kansuis 50 weight portions
Semen Ricini 30 weight portion Camphoras 30 weight portion Mentholums 30 weight portions.
3. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
The A group:
Bufo siccus 1400 weight portion Herba speranskiae tuberculataes 110 weight portion Semen Strychni 140 weight portions
Olibanum 40 weight portion Myrrhas 80 weight portion Semen Momordicaes 30 weight portions
Radix Aconiti 50 weight portion Radix Aconiti Kusnezoffii 30 weight portion Rhizoma Arisaematis 50 weight portions
Semen daturae 30 weight portion Herba Asaris 50 weight portion rhizoma sparganic 30 weight portions
Rhizoma Curcumae 70 weight portion Flos Carthamis 30 weight portion Semen Persicaes 70 weight portions
The Cortex Eucommiae 30 weight portion Radix Dipsacis 70 weight portion Herba Taxillis 30 weight portions
Rhizoma Et Radix Notopterygii 70 weight portion Radix Angelicae Pubescentiss 30 weight portion Radix Clematidis 70 weight portions
Radix Cyathulae 30 weight portions;
The B group:
Stir-baked SQUAMA MANITIS 70 weight portion Sanguis Draxonis 20 weight portion Flos Caryophyllis 40 weight portions
The Rhizoma Acori Graminei 30 weight portion Radixs Angelicae Dahuricae 70 weight portion Semen Impatientis 20 weight portions
Radix Notoginseng 70 weight portion Herba Ephedraes 30 weight portion Radix Kansuis 70 weight portions
Semen Ricini 20 weight portion Camphoras 40 weight portion Mentholums 20 weight portions.
4. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
The A group:
Bufo siccus 600 weight portion Herba speranskiae tuberculataes 190 weight portion Semen Strychni 60 weight portions
Olibanum 80 weight portion Myrrhas 40 weight portion Semen Momordicaes 50 weight portions
Radix Aconiti 30 weight portion Radix Aconiti Kusnezoffii 50 weight portion Rhizoma Arisaematis 30 weight portions
Semen daturae 50 weight portion Herba Asaris 30 weight portion rhizoma sparganic 70 weight portions
Rhizoma Curcumae 30 weight portion Flos Carthamis 70 weight portion Semen Persicaes 30 weight portions
The Cortex Eucommiae 70 weight portion Radix Dipsacis 30 weight portion Herba Taxillis 70 weight portions
Rhizoma Et Radix Notopterygii 30 weight portion Radix Angelicae Pubescentiss 70 weight portion Radix Clematidis 30 weight portions
Radix Cyathulae 70 weight portions;
The B group:
Stir-baked SQUAMA MANITIS 30 weight portion Sanguis Draxonis 40 weight portion Flos Caryophyllis 20 weight portions
The Rhizoma Acori Graminei 70 weight portion Radixs Angelicae Dahuricae 30 weight portion Semen Impatientis 40 weight portions
Radix Notoginseng 30 weight portion Herba Ephedraes 70 weight portion Radix Kansuis 30 weight portions
Semen Ricini 40 weight portion Camphoras 20 weight portion Mentholums 40 weight portions.
5. as claim 1,2,3 or 4 arbitrary described preparation of drug combination methods, it is characterized in that this method is:
Be equipped with medicine: A is organized drug immersion 5-7 days with Oleum sesami 2000-4000 weight portion; B is organized medicine, and to be ground into thin medicated powder standby;
Explosive: the heating of soaked A group medicine is decocted, be dark brown to the medicine outside, inner sallow being advisable removed medicinal residues and filtered, and promptly gets medicine oil;
Oil refining: with the heating of medicine oil, oil smoke is that light cyan gradually becomes black dense smoke, becomes white dense smoke by black smoke, and oil refining is finished;
Pilling and pasting: the medicine oil that will refine is cold slightly from fire, when treating oily temperature drop to 280-300 ℃, add Plumbum preparatium 1000-2000 weight portion in the oil inchmeal, ceaselessly stir along a direction simultaneously, prevent that Plumbum preparatium from sinking to the bottom of a pan, this moment, medicine oil can violently seethe with excitement, and the surface has a large amount of foams and zest dense smoke to produce, after medicine oil and Plumbum preparatium reaction finish, get the liquid plaster;
Old tender test: the liquid plaster that takes a morsel splashes in the cold water, treats that the liquid plaster solidifies the back and takes out, and as sticking hands, tearing hands has silk, and the expression ointment is tender excessively, should continue to decoct, and is promptly disconnected as if what tear, then for old excessively, should endure with Oleum sesami, until old tender suitable again;
Releasing fire-toxin: will refine good plaster, and pour at leisure and soak in the water, and change water constantly, and after the cooling, change water every day 1 time, soak 5-7 days;
The stand plaster: the plaster water proof heating behind the detoxification is dissolved, add the B that has got ready and organize thin medicated powder, add far infrared ceramic powder 20-60 weight portion, the infiltration of azone 5-15 parts by volume again, stir, keep 70-90 ℃ temperature, spread out in plaster and stick, after cooling, cover lining paper, seal in the plastic bag of packing into, put the moon and dry the preservation of dry place, promptly get black plaster.
6. preparation of drug combination method as claimed in claim 5 is characterized in that this method is:
Be equipped with medicine: A was organized drug immersion 6 days with Oleum sesami 3000 weight portions; B is organized medicine, and to be ground into thin medicated powder standby;
Explosive: the heating of soaked A group medicine is decocted, be dark brown to the medicine outside, inner sallow being advisable removed medicinal residues and filtered, and promptly gets medicine oil;
Oil refining: with the heating of medicine oil, oil smoke is that light cyan gradually becomes black dense smoke, becomes white dense smoke by black smoke, and oil refining is finished;
Pilling and pasting: the medicine oil that will refine is cold slightly from fire, when treating oily temperature drop to 280-300 ℃, add Plumbum preparatium 1500 weight portions in the oil inchmeal, ceaselessly stir along a direction simultaneously, prevent that Plumbum preparatium from sinking to the bottom of a pan, this moment, medicine oil can violently seethe with excitement, and the surface has a large amount of foams and zest dense smoke to produce, after medicine oil and Plumbum preparatium reaction finish, get the liquid plaster;
Old tender test: the liquid plaster that takes a morsel splashes in the cold water, treats that the liquid plaster solidifies the back and takes out, and as sticking hands, tearing hands has silk, and the expression ointment is tender excessively, should continue to decoct, and is promptly disconnected as if what tear, then for old excessively, should endure with Oleum sesami, until old tender suitable again;
Releasing fire-toxin: will refine good plaster, and pour at leisure and soak in the water, and change water constantly, and after the cooling, change water every day 1 time, soak 6 days;
The stand plaster: the plaster water proof heating behind the detoxification is dissolved, add the B that has got ready and organize thin medicated powder, add far infrared ceramic powder 40 weight portions, the infiltration of azone 10 parts by volume again, stir, keep 70-90 ℃ temperature, spread out in plaster and stick, after cooling, cover lining paper, seal in the plastic bag of packing into, put the moon and dry the preservation of dry place, promptly get black plaster.
7. as claim 1,2,3 or 4 arbitrary described preparation of drug combination methods, it is characterized in that this method is:
Prepare the dried medicated powder that soaks: B is organized medicine, and to be ground into thin medicated powder standby; Get Bufo siccus, Olibanum, Myrrha in the A group, friedly in 500-1500 parts by volume Oleum sesami be dark brown, filter, become breast not have Bufo siccus oil to the outside, standby; Again all the other 19 herbal medicines in the A group are decocted with water extraction, filters three times, filtrate concentrates, and adds B and organizes thin medicated powder, stir evenly, dry, pulverize, 120 mesh sieves standby, promptly get the dried medicated powder that soaks;
Preparation Colophonium plaster: breast is not had Bufo siccus oil, Colophonium 5500-6000 weight portion, Cera Flava 700-800 weight portion mixing heat fused, along with oily temperature increases, begin to occur black smoke in the pot, the stirring that do not stop this moment, when black dense smoke became white dense smoke by Zhejiang, the sign lubricate was about to be boiled into, and does old tender test turning off stove, when temperature is reduced to 60-80 ℃, add the dried medicated powder that soaks again, far infrared ceramic powder 60-100 weight portion, azone 10-30 parts by volume is mixed thoroughly, promptly gets the Colophonium plaster, spread out in plaster and stick, cover lining paper, seal in the plastic bag of packing into, re-use after putting into the freezing 24-72 of refrigerator hour releasing fire-toxin.
8. preparation of drug combination method as claimed in claim 7 is characterized in that this method is:
Prepare the dried medicated powder that soaks: B is organized medicine, and to be ground into thin medicated powder standby; Get Bufo siccus, Olibanum, Myrrha in the A group, friedly in 1000 parts by volume Oleum sesami be dark brown, filter, become breast not have Bufo siccus oil to the outside, standby; Again all the other 19 herbal medicines in the A group are decocted with water extraction, filters three times, filtrate concentrates, and adds B and organizes thin medicated powder, stir evenly, dry, pulverize, 120 mesh sieves standby, promptly get the dried medicated powder that soaks;
Preparation Colophonium plaster: breast is not had Bufo siccus oil, Colophonium 5800 weight portions, Cera Flava 750 weight portion mixing heat fused, along with oily temperature increases, begin to occur black smoke in the pot, the stirring that do not stop this moment, when black dense smoke became white dense smoke by Zhejiang, the sign lubricate was about to be boiled into, and does old tender test turning off stove, when temperature is reduced to 70 ℃, add the dried medicated powder that soaks again, far infrared ceramic powder 80 weight portions, azone 20 parts by volume are mixed thoroughly, promptly get the Colophonium plaster, spread out in plaster and stick, cover lining paper, seal in the plastic bag of packing into, put into refrigerator and re-used behind the releasing fire-toxin in freezing 48 hours.
9. as claim 1,2,3 or 4 arbitrary described pharmaceutical compositions, it is characterized in that this pharmaceutical composition adds pharmaceutically conventional adjuvant according to common process and makes in powder, liniment, emplastrum, red unguentum, black unguentum, spray, ointment, ointment or the medicated wine of clinical acceptance any one.
10. as claim 1,2, the application of 3 or 4 arbitrary described pharmaceutical compositions in the medicine of preparation treatment arthromyodynia.
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| CN2009100869228A CN101926957B (en) | 2009-06-18 | 2009-06-18 | Medicinal composition for treating arthralgia syndrome and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009100869228A CN101926957B (en) | 2009-06-18 | 2009-06-18 | Medicinal composition for treating arthralgia syndrome and preparation method thereof |
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| CN102198229A (en) * | 2011-05-18 | 2011-09-28 | 深圳市九恩堂科技有限公司 | Massage liquid for activating collaterals |
| CN102526336A (en) * | 2012-01-16 | 2012-07-04 | 李仁君 | Chinese medicinal formulation for treating traumatic injury and rheumatic arthralgia |
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| CN102198229A (en) * | 2011-05-18 | 2011-09-28 | 深圳市九恩堂科技有限公司 | Massage liquid for activating collaterals |
| CN102526336A (en) * | 2012-01-16 | 2012-07-04 | 李仁君 | Chinese medicinal formulation for treating traumatic injury and rheumatic arthralgia |
| CN102526336B (en) * | 2012-01-16 | 2013-07-31 | 李仁君 | Chinese medicinal formulation for treating traumatic injury and rheumatic arthralgia |
| CN102670829A (en) * | 2012-05-16 | 2012-09-19 | 宁书慧 | Far infrared ceramic powder-contained black plaster and preparation method |
| CN103784667A (en) * | 2014-03-04 | 2014-05-14 | 邓飞武 | Externally-used Chinese herbal medicine liquor for treating rheumatoidbone disease and preparation and usage method thereof |
| CN103961594A (en) * | 2014-05-14 | 2014-08-06 | 马鞍山科信咨询有限公司 | Ointment for treating talalgia |
| CN105106863A (en) * | 2015-09-24 | 2015-12-02 | 王钦存 | Traditional Chinese medicine for treating hyperostosis |
| CN105709021A (en) * | 2016-03-14 | 2016-06-29 | 张春荣 | Muscle and bone recovery unguent and preparation method thereof |
| CN107519362A (en) * | 2017-10-16 | 2017-12-29 | 耿峰 | A kind of Chinese medicinal plaster and its production and use |
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