CN1319513C - Skin-care composition - Google Patents
Skin-care composition Download PDFInfo
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- CN1319513C CN1319513C CNB031180833A CN03118083A CN1319513C CN 1319513 C CN1319513 C CN 1319513C CN B031180833 A CNB031180833 A CN B031180833A CN 03118083 A CN03118083 A CN 03118083A CN 1319513 C CN1319513 C CN 1319513C
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- leaf
- cyclocarya paliurus
- paliurus iljinskaja
- extract
- skin
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Abstract
The present invention relates to a skin care composition which comprises effective quantity of safe Qingqian Willow leaf extract, and a carrier which is accepted by skin, wherein the carrier can be bath foam, skin cream, toilet powder, perfume, etc.
Description
Technical field
The present invention relates to a kind of skin care compositions that contains plant extract and preparation method thereof.
Background technology
Cyclocarya paliurus Iljinskaja Cyclocarya paliurus (Batal.) Iljinskaja is the high megaphanerophyte of Dicotyledoneae (Dicotyledoneae) Juglandaceae (Juglandaceae) plant cyclocarya, being distributed widely in ground such as Jiangxi, Zhejiang, Soviet Union, Anhui, platform, Hubei Province, Hunan, river, Guangdong, osmanthus, Guizhou Province, Yunnan, is the natural resources of China's preciousness.Preliminary study shows that it has multiple physiology and the pharmacological function useful to health, as blood pressure lowering, blood fat reducing, blood sugar lowering, anoxia enduring, endurance etc., is a kind of product that very big DEVELOPMENT PROSPECT is arranged.89100023), Chinese patent application " tea for constipation " (number of patent application: 96117174), " a kind of leaf of Cyclocarya paliurus Iljinskaja health food and manufacture method thereof " (number of patent application: 01122767), " a kind of buccal tablet of Qingqian Willow leaf " (number of patent application: 00126245) disclose the blood pressure lowering, blood fat reducing, blood sugar lowering pharmacology function of Cyclocarya paliurus Iljinskaja Chinese patent " is the method for feedstock production health tea with the Cyclocarya paliurus Iljinskaja " (patent No.: in beverage, Application in Food.
Summary of the invention
Discover that through the applicant leaf of Cyclocarya paliurus Iljinskaja extract has stronger inhibitory action to staphylococcus aureus, beta hemolytic streptococcus, Streptococcus mutans etc.Experimental technique and result are as follows:
1, test material
1.1 medicine: leaf of Cyclocarya paliurus Iljinskaja extract
1.2 strain: staphylococcus aureus (S.aureus ATCC25923), beta hemolytic streptococcus (β-hemolytic streptococcus), Streptococcus mutans (S.mutans, Sm)
1.3 culture medium: Nutrient agar (or serum Nutrient agar)
2, method and result
2.1 the preparation of bacterium liquid: above-mentioned each bacterial isolates increased bacterium 18 hours for 37 ℃, became to use concentration, about 1 * 10 for 100 times with the physiological saline solution dilution
7/ ml.
The sterile working draws an amount of physiological saline solution and joins in the mycete slant tube, makes bacteria suspension, makes its OD600nm value be 0.05.
2.2 drug dilution: medicine dilutes with physiological saline solution respectively, every pipe 4ml, and making its ultimate density is 10%, 5%, 2.5%, 1.25%.The Oxford agar diffusion method is adopted in external antibacterium effect, cultivates 24 hours observed results for 37 ℃.
2.3 result
2.3.1 the external antibacterium effect of medicine (antibacterial circle diameter: mm, four meansigma methodss)
| Drug level | Bacterial strain | ||
| Staphylococcus aureus | Group B streptococcus | Streptococcus mutans | |
| 10％ | 20 | 18 | 18 |
| 5％ | 16 | 15 | 15 |
| 2.5％ | 12 | 13 | 13 |
| 12.5％ | 0 | 0 | 0 |
Antibacterial circle diameter 15mm is above to be extremely sensitive, and 10-14mm is a medium sensitivity, and 9mm is following to be low responsive.
The above results shows that the pathogenic bacterium that much cause dermatosis can be used for preventing and treating dermatosis to the leaf of Cyclocarya paliurus Iljinskaja extract sensitivity.
The preparation method of leaf of Cyclocarya paliurus Iljinskaja extract can be:
Method 1: will select leaf of Cyclocarya paliurus Iljinskaja 80-105 ℃ of oven dry, make moisture≤8%.Dry leaf of Cyclocarya paliurus Iljinskaja is pulverized, crossed 50 mesh sieves.Add 5-10 water doubly, temperature 60-90 ℃ following flooding 3-10 hour, repeat twice, filter and remove residue is got supernatant, merging filtrate.Filtrate sucks vacuum concentration pot, is concentrated into the heavy 1/2-1/3 of material under 0.04-0.08MPa vacuum.Concentrate feed carries out spray drying, and 160-180 ℃ of spray drying control inlet temperature, is drying to obtain the powder of yellowish-brown leaf of Cyclocarya paliurus Iljinskaja extract by leaving air temp 70-85 ℃.Water-soluble.
Method 2: will select leaf of Cyclocarya paliurus Iljinskaja 80-105 ℃ of oven dry, make moisture≤8%.Dry leaf of Cyclocarya paliurus Iljinskaja is pulverized, crossed 50 mesh sieves.Add 5 times 70% alcoholic solution lixiviate, reflux three times, each 1 hour, merge ethanol extract; Concentrating under reduced pressure with the petroleum ether leaching, and reclaims petroleum ether; Reuse chloroform lixiviate 30 minutes, and reclaim chloroform; Ethyl acetate lixiviate secondary, each 40 minutes, merge extractive liquid,, the cryogenic vacuum evaporation, concentrated solution promptly obtains the powder of yellowish-brown leaf of Cyclocarya paliurus Iljinskaja extract through lyophilization.Water-soluble.
Comprise safe and effective amount, the leaf of Cyclocarya paliurus Iljinskaja extract of preferred 2.5 to 10 percetages by weight, and skin acceptable carrier in the skin care compositions of the present invention.
Skin acceptable carrier described in the skin care compositions of the present invention is bath foam, protective skin cream, talcum powder, perfume etc.
According to reported in literature, leaf of Cyclocarya paliurus Iljinskaja decoct 68.0g/L (being equivalent to 4300mg/kg) and following dosage are not seen obvious maternal toxicity effect and fetal toxicity effect, no teratogenesis to rat oral gavage.
Be several components of skin care compositions of the present invention below:
1, bath foam
Below be percetage by weight (%):
Leaf of Cyclocarya paliurus Iljinskaja extract (2 making as stated above) 2.5-10.0, essence 1.0-5.0, alkylolamides 1.0-3.0, lauryl alcohol sulfuric acid 20.0-40.0, all the other are deionized water.
2, protective skin cream
Below be percetage by weight (%):
Leaf of Cyclocarya paliurus Iljinskaja extract (1 making as stated above) 2.5-10.0, stearic acid 6.0-10.0, stearyl alcohol 2.0-6.0, stearic acid butyl ester 4.0-8.0, propylene glycol 4.0-6.0, glyceryl monostearate 1.0-3.0, potassium hydroxide 0.2-0.6, tocopheryl acetate 0.1-0.3, essence 0.1-0.8, all the other are deionized water.
3, talcum powder
Below be percetage by weight (%):
Leaf of Cyclocarya paliurus Iljinskaja extract (1 making as stated above) 2.5-10.0, Borneolum Syntheticum powder 0.1-0.5, all the other are Pulvis Talci.
4, perfume
Below be percetage by weight (%):
Leaf of Cyclocarya paliurus Iljinskaja extract (1 making as stated above) 2.5-10.0, essence 3.0-8.0, deionized water 5.0-15.0, all the other are 95% ethanol.
The specific embodiment
Embodiment 1:
The percetage by weight (%) that raw material is formed is:
Leaf of Cyclocarya paliurus Iljinskaja extract (1 making as stated above) 10.0, essence 3.0, alkylolamides 2.0, lauryl alcohol sulfuric acid 30.0, all the other are deionized water.
Preparation method: with essence, alkylolamides, lauryl alcohol sulfuric acid and leaf of Cyclocarya paliurus Iljinskaja extract mix successively, and mix on the limit, and the limit stirs, and adds deionized water at last again, stir, sterilization, packing promptly gets the bath foam finished product.
Embodiment 2:
The percetage by weight (%) that raw material is formed is:
Leaf of Cyclocarya paliurus Iljinskaja extract (1 making as stated above) 8.0, stearic acid 8.0, stearyl alcohol 4.0, stearic acid butyl ester 6.0, propylene glycol 5.0, glyceryl monostearate 2.0, potassium hydroxide 0.4, tocopheryl acetate 0.3, essence 0.3, all the other are deionized water.
Preparation method: leaf of Cyclocarya paliurus Iljinskaja extract, propylene glycol, potassium hydroxide are added in the entry, adjust 70 ℃ of heating.Oil content dissolving back is added glyceryl monostearate,, this oil phase is added to aqueous phase carries out pre-emulsifying 70 ℃ of adjustment, use blender with the emulsified particle homogeneous, in the time of 50 ℃, add tocopheryl acetate, essence, after restir was even, deoxidation, filtration, cooling, bottling promptly got the protective skin cream finished product.
Embodiment 3:
The percetage by weight (%) that raw material is formed is:
Leaf of Cyclocarya paliurus Iljinskaja extract (1 making as stated above) 5.0, Borneolum Syntheticum powder 0.5, Pulvis Talci 94.5.
Preparation method: raw material is put into dry blender stir, the back bottling sealing of sieving promptly gets the talcum powder finished product.
Embodiment 4:
The percetage by weight (%) that raw material is formed is:
Leaf of Cyclocarya paliurus Iljinskaja extract (2 making as stated above) 2.5, essence 6.0, deionized water 10.0, all the other are 95% ethanol.
Preparation method: leaf of Cyclocarya paliurus Iljinskaja extract, essence are dissolved in the deionized water, mix with ethanol again, through store, freezing, filtration, additive color, bottling promptly get the perfume finished product.
Embodiment 5:
Below be the fungistatic effect of the protective skin cream that makes by embodiment 2, test method is identical with the antibacterial tests of above-mentioned leaf of Cyclocarya paliurus Iljinskaja extract:
| Protective skin cream | Bacterial strain | ||
| Staphylococcus aureus | Group B streptococcus | Streptococcus mutans | |
| The Cyclocarya paliurus Iljinskaja protective skin cream | 18 | 16 | 16 |
| Blank protective skin cream | 0 | 0 | 0 |
Antibacterial circle diameter 15mm is above to be extremely sensitive, and 10-14mm is a medium sensitivity, and 9mm is following to be low responsive.
Claims (2)
1, a kind of skin care compositions is characterized in that it comprises the leaf of Cyclocarya paliurus Iljinskaja extract of 2.5 to 10 percetages by weight, and skin acceptable carrier, and described leaf of Cyclocarya paliurus Iljinskaja extract is obtained by one of following method:
A, will select leaf of Cyclocarya paliurus Iljinskaja 80-105 ℃ of oven dry, make moisture≤8%; Dry leaf of Cyclocarya paliurus Iljinskaja is pulverized, crossed 50 mesh sieves; Add 5-10 water doubly, temperature 60-90 ℃ following flooding 3-10 hour, repeat twice, filter and remove residue is got supernatant, merging filtrate; Filtrate sucks vacuum concentration pot, is concentrated into the heavy 1/2-1/3 of material under 0.04-0.08MPa vacuum; Concentrate feed carries out spray drying, and 160-180 ℃ of spray drying control inlet temperature, is drying to obtain the powder of yellowish-brown leaf of Cyclocarya paliurus Iljinskaja extract by leaving air temp 70-85 ℃;
B, will select leaf of Cyclocarya paliurus Iljinskaja 80-105 ℃ of oven dry, make moisture≤8%; Dry leaf of Cyclocarya paliurus Iljinskaja is pulverized, crossed 50 mesh sieves; Add 5 times 70% alcoholic solution lixiviate, reflux three times, each 1 hour, merge ethanol extract; Concentrating under reduced pressure with the petroleum ether leaching, and reclaims petroleum ether; Reuse chloroform lixiviate 30 minutes, and reclaim chloroform; Ethyl acetate lixiviate secondary, each 40 minutes, merge extractive liquid,, the cryogenic vacuum evaporation, concentrated solution promptly obtains the powder of yellowish-brown leaf of Cyclocarya paliurus Iljinskaja extract through lyophilization.
2, a kind of compositions as claimed in claim 1 is characterized in that described skin acceptable carrier is bath foam, protective skin cream, talcum powder, perfume.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031180833A CN1319513C (en) | 2003-02-12 | 2003-02-12 | Skin-care composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031180833A CN1319513C (en) | 2003-02-12 | 2003-02-12 | Skin-care composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1520803A CN1520803A (en) | 2004-08-18 |
| CN1319513C true CN1319513C (en) | 2007-06-06 |
Family
ID=34284817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031180833A Expired - Fee Related CN1319513C (en) | 2003-02-12 | 2003-02-12 | Skin-care composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1319513C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3129084A1 (en) * | 2021-11-16 | 2023-05-19 | L'Arboretum | Cosmetic composition |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716060B (en) * | 2012-07-10 | 2013-08-14 | 中国国旅贸易有限责任公司 | Pine needle powder-superfine microcrystalline cellulose toilet powder and manufacturing method thereof |
| CN108158936A (en) * | 2018-02-09 | 2018-06-15 | 广西北海苗康生物科技有限公司 | A kind of blue or green money willow pearl skin care liquid and preparation method |
| CN111956547A (en) * | 2020-08-21 | 2020-11-20 | 广东柏俐臣生物科技有限公司 | Anti-inflammatory and soothing composition and application thereof |
| CN114099376B (en) * | 2020-08-25 | 2024-08-27 | 四川大学华西医院 | Use of cyclocarya paliurus leaves or extracts thereof in preparation of antibacterial cosmetics |
| CN114377054B (en) * | 2020-10-16 | 2023-08-15 | 四川大学华西医院 | Use of cyclocarya paliurus leaves or extracts thereof in preparation of drugs or cosmetics for preventing and/or treating acne |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1043863A (en) * | 1988-12-30 | 1990-07-18 | 修水县茶桑水果局 | With the blue or green money willow method that is the feedstock production health tea |
| CN1297743A (en) * | 2000-08-22 | 2001-06-06 | 樊华轩 | Buccal tablet of Qingqian Willow leaf |
-
2003
- 2003-02-12 CN CNB031180833A patent/CN1319513C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1043863A (en) * | 1988-12-30 | 1990-07-18 | 修水县茶桑水果局 | With the blue or green money willow method that is the feedstock production health tea |
| CN1297743A (en) * | 2000-08-22 | 2001-06-06 | 樊华轩 | Buccal tablet of Qingqian Willow leaf |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3129084A1 (en) * | 2021-11-16 | 2023-05-19 | L'Arboretum | Cosmetic composition |
| WO2023088980A1 (en) * | 2021-11-16 | 2023-05-25 | L'Arboretum | Cosmetic composition comprising birch sap, maple sap, willow leaf extract and ginkgo biloba leaf extract |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1520803A (en) | 2004-08-18 |
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