CN1318039C - Instant agent of donkey-hide gelatin and preparation method - Google Patents
Instant agent of donkey-hide gelatin and preparation method Download PDFInfo
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- CN1318039C CN1318039C CNB031390552A CN03139055A CN1318039C CN 1318039 C CN1318039 C CN 1318039C CN B031390552 A CNB031390552 A CN B031390552A CN 03139055 A CN03139055 A CN 03139055A CN 1318039 C CN1318039 C CN 1318039C
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Abstract
The present invention discloses an instant agent of donkey-hide gelatin and a preparation method thereof, which relates to a Chinese medical preparation and a preparation method thereof, particularly to an instant agent preparation and a preparation method thereof. The instant agent of donkey-hide gelatin is prepared from finished product donkey-hide gelatin to which a plurality of procedures of gelatin powder preparation, boiling granulation, drying and packaging are carried out. Compared with an original preparation method, the technique of the present invention has the advantages of little investment, short production period, high productive efficiency, low production cost, advanced technique, high finished product yield, good dissolving performance and mouth feel, etc. The present invention is especially suitable for applying to the existing donkey-hide gelatin producing enterprise.
Description
Affiliated technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, particularly a kind of instant preparation and preparation method thereof.
Background technology
Colla Corii Asini is a kind of Chinese medicine, traditional Colla Corii Asini is a lamellar, need be processed into fritter when taking, heat and take after dissolving, CN1079148A discloses a kind of preparation method of instant ass-hide gelatin, solve Colla Corii Asini and taken inconvenient problem, a series of complicated step such as but this production technology is donkey skin is selected, washing, unhairing, stripping and slicing, decoction, concentrate are made thick paste, the spray-dried again electuary of making, in the production process, condition is wayward, and easily produces wall sticking phenomenon in spray drying boiling granulating process, and yield is very low.CN1119527A discloses the preparation method of a kind of granulated donkey-hide gelatin, Cornu Cervi, Colla Plastri Testudinis, but the used atomisation pressure of this preparation method is 0.2-0.35mpa, and aux. pressure is 0.015-0.025mpa, the aux. pressure requirement that is not accordant to the old routine, and lack the negative pressure index, be difficult to produce qualified products.
Summary of the invention
The purpose of this invention is to provide a kind of is the instant e-jiao granules that raw material is made with the finished product Colla Corii Asini, and another object of the present invention provides the preparation method of this electuary.
The present invention is achieved by the following technical solutions, and instant e-jiao granules is to be that raw material is used with the Colla Corii Asini
The pharmaceutical preparation of following prepared,
A. rubber powder preparation: it is 80-120 order fine powder that the Colla Corii Asini piece is ground into granularity.
B. boiling granulating: the Colla Corii Asini powder is put in the material container of boiling granulating machine, the binding agent that adds Colla Corii Asini weight 2-3% carries out boiling granulating, and atomisation pressure is 0.25-0.35mpa, and assistant spray pressure is 0.05-0.2mpa, and negative pressure is 2000-6000pa.Making and making particulate standard is can must not be higher than 8% by the granule and the powder sum of No. four sieves by a sieve;
C. oven dry: 105 ℃ of following drying and sterilizing to moistures in the qualified granule placement baking oven are no more than 5%;
D. packing: the packing material of packing into of the donkey-hide gelatin granule after will sterilizing.
Binding agent can or contain the Colla Corii Asini juice of Colla Corii Asini 5-10% for purified water.
The preparation method of instant e-jiao granules,
A. rubber powder preparation: it is 80-120 order fine powder that the Colla Corii Asini piece is ground into granularity.
B. boiling granulating: the Colla Corii Asini powder is put in the material container of boiling granulating machine, the binding agent that adds Colla Corii Asini weight 2-3% carries out boiling granulating, and atomisation pressure is 0.25-0.35Mpa, and assistant spray pressure is 0.05-0.2Mpa, and negative pressure is 2000-6000pa.Making and making particulate standard is and can must not be higher than 8% by the granule and the powder sum of No. four sieves by a sieve;
C. oven dry: 105 ℃ of following drying and sterilizing to moistures in the qualified granule placement baking oven are no more than 5%;
D. packing: the packing material of packing into of the donkey-hide gelatin granule after will sterilizing.
The optimization numerical value of atomisation pressure is that 0.28-0.32Mpa assistant spray pressure is 0.10-0.15Mpa, and negative pressure is 3000-4000pa.
The optimal value of atomisation pressure is 0.30Mpa, and assistant spray pressure is 0.13Mpa, and negative pressure is 4000pa.
The instructions of taking of medicine of the present invention is: day clothes 1-2 time, each 3-9 gram.Be applicable to that all crowds that need take Colla Corii Asini take.
Process characteristic of the present invention is, uses explained hereafter donkey-hide gelatin granule efficient height of the present invention, and product particle is even.
The invention has the beneficial effects as follows with explained hereafter instant e-jiao granules of the present invention it is that the finished product Colla Corii Asini produced with traditional handicraft is as crude drug, a kind of new Colla Corii Asini product forms of making, its production process is simple, and the finished product Colla Corii Asini uses original equipment and traditional handicraft, and product quality is easy to control.Only increase pulverizing, boiling granulating and three step of packing simple physics process in the production technology, compare the change of no matter with the Colla Corii Asini production technology, guarantee that fully product is in full accord with original Colla Corii Asini function curative effect, the preparation method that technology of the present invention provides than documents 1, has small investment, with short production cycle, advantage such as efficient is high, cost is low, product yield is high, melting and mouthfeel are all better.There is technological parameter complete, advanced, practical than documents 2, is specially adapted to existing Colla Corii Asini manufacturing enterprise and uses.
The specific embodiment
Realization the specific embodiment of the present invention is:
Embodiment 1, and a kind of instant e-jiao granules is to be the pharmaceutical preparation of raw material with following prepared with the Colla Corii Asini,
A. rubber powder preparation: it is 100 purpose fine powders that Colla Corii Asini piece (water content 5-15%) is ground into granularity.
B. boiling granulating: the Colla Corii Asini powder is put in the material container of boiling granulating machine, the purified water that adds Colla Corii Asini weight 2-3% is that binding agent carries out boiling granulating, and atomisation pressure is 0.30Mpa, and assistant spray pressure is 0.13Mpa, and negative pressure is 4000pa.Making and making particulate standard is and can must not be higher than 8% by the granule and the powder sum of No. four sieves by a sieve;
C. oven dry: 105 ℃ of following drying and sterilizing to moistures in the qualified granule placement baking oven are no more than 5%;
D. packing: the packing material of packing into of the donkey-hide gelatin granule after will sterilizing.
Embodiment 2, and basic technology is with embodiment 1 but binding agent is the glue juice that contains Colla Corii Asini 5%.
Embodiment 3, basic technology with embodiment 1 but atomisation pressure is 0.25Mpa during boiling granulating, assistant spray pressure is 0.10Mpa, negative pressure is 3000pa.
Embodiment 4, basic technology with embodiment 1 but atomisation pressure is 0.35Mpa during boiling granulating, assistant spray pressure is 0.2Mpa, negative pressure is 6000pa.
Embodiment 5, basic technology with embodiment 1 and 2 but atomisation pressure is 0.28Mpa during boiling granulating, assistant spray pressure is 0.15Mpa, negative pressure is 5000p.
Claims (3)
1. the preparation method of an instant e-jiao granules is characterized in that:
A. rubber powder preparation: it is 80-120 order fine powder that the Colla Corii Asini piece is ground into granularity;
B. boiling granulating: the Colla Corii Asini powder is put in the material container of boiling granulating machine, the binding agent that adds Colla Corii Asini weight 2-3% carries out boiling granulating, atomisation pressure is 0.25-0.35Mpa, assistant spray pressure is 0.05-0.2Mpa, negative pressure is 2000-6000pa, and making and making particulate standard is and can must not be higher than 8% by the granule and the powder sum of No. four sieves by a sieve;
C. oven dry: 105 ℃ of following drying and sterilizing to moistures in the qualified granule placement baking oven are no more than 5%;
D. packing: the packing material of packing into of the donkey-hide gelatin granule after will sterilizing.
2. the preparation method of instant e-jiao granules according to claim 1, it is characterized in that: atomisation pressure is 0.28-0.32Mpa, and assistant spray pressure is 0.10-0.15Mpa, and negative pressure is 3000-4000pa.
3. the preparation method of instant e-jiao granules according to claim 1 and 2, it is characterized in that: atomisation pressure is 0.30Mpa, and assistant spray pressure is 0.13Mpa, and negative pressure is 4000pa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031390552A CN1318039C (en) | 2003-09-23 | 2003-09-23 | Instant agent of donkey-hide gelatin and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031390552A CN1318039C (en) | 2003-09-23 | 2003-09-23 | Instant agent of donkey-hide gelatin and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1600320A CN1600320A (en) | 2005-03-30 |
| CN1318039C true CN1318039C (en) | 2007-05-30 |
Family
ID=34659284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031390552A Expired - Lifetime CN1318039C (en) | 2003-09-23 | 2003-09-23 | Instant agent of donkey-hide gelatin and preparation method |
Country Status (1)
| Country | Link |
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| CN (1) | CN1318039C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100427102C (en) * | 2006-06-14 | 2008-10-22 | 孙明 | Preparation of nanometer donkey-hide gelatin powder and its gelatin product |
| CN108926524B (en) * | 2018-01-30 | 2020-07-17 | 东阿阿胶股份有限公司 | Instant gelatin product block and preparation method thereof |
| CN109010372B (en) * | 2018-09-21 | 2020-11-13 | 东阿阿胶股份有限公司 | Instant preparation of colloid traditional Chinese medicine and its adjuvant-free direct compression technique |
| CN109589338B (en) * | 2018-12-28 | 2020-06-09 | 东阿阿胶股份有限公司 | Instant curing method for microporous structure of glue instant product |
| CN109645529B (en) * | 2019-02-21 | 2021-08-06 | 湖北人缘堂医药生物工程有限公司 | Preparation method of food pills |
| CN115644437A (en) * | 2022-10-28 | 2023-01-31 | 东阿阿胶保健品有限公司 | Portable donkey-hide gelatin-containing fruit and vegetable instant composite particle and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058338A (en) * | 1990-08-13 | 1992-02-05 | 山东东阿阿胶厂 | The preparation method of instant ass-hide gelatin |
| CN1092656A (en) * | 1994-01-14 | 1994-09-28 | 山东省东阿阿胶(集团)股份有限公司 | Donkey-hide gelatin beverage and preparation method thereof |
| CN1119527A (en) * | 1994-09-30 | 1996-04-03 | 衡阳中药二厂 | Method for preparation of granulated donkey-hide gelatin, antler glue and tortoise-plastron glue |
-
2003
- 2003-09-23 CN CNB031390552A patent/CN1318039C/en not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058338A (en) * | 1990-08-13 | 1992-02-05 | 山东东阿阿胶厂 | The preparation method of instant ass-hide gelatin |
| CN1092656A (en) * | 1994-01-14 | 1994-09-28 | 山东省东阿阿胶(集团)股份有限公司 | Donkey-hide gelatin beverage and preparation method thereof |
| CN1119527A (en) * | 1994-09-30 | 1996-04-03 | 衡阳中药二厂 | Method for preparation of granulated donkey-hide gelatin, antler glue and tortoise-plastron glue |
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| Publication number | Publication date |
|---|---|
| CN1600320A (en) | 2005-03-30 |
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Address after: An urban road in Pingyin County of Ji'nan City, 250409 monitoring in Shandong Province Patentee after: SHANDONG FUPAI PHARMACEUTICAL CO.,LTD. Address before: 250400 63 Zhenxing street, Pingyin County, Shandong Patentee before: Shandong Fujiao Group Co.,Ltd. |
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Granted publication date: 20070530 |
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