CN1309290A - Multi-channel converter for optical fibre sensors to continuously measure solubility of medicine - Google Patents

Multi-channel converter for optical fibre sensors to continuously measure solubility of medicine Download PDF

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Publication number
CN1309290A
CN1309290A CN01108834A CN01108834A CN1309290A CN 1309290 A CN1309290 A CN 1309290A CN 01108834 A CN01108834 A CN 01108834A CN 01108834 A CN01108834 A CN 01108834A CN 1309290 A CN1309290 A CN 1309290A
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China
Prior art keywords
optical fibre
fibre
rotating disk
single channel
shell
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Granted
Application number
CN01108834A
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Chinese (zh)
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CN1139798C (en
Inventor
陈坚
吴韬
王清文
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Xinjiang Medical University
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Xinjiang Medical University
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Priority to CNB011088346A priority Critical patent/CN1139798C/en
Publication of CN1309290A publication Critical patent/CN1309290A/en
Application granted granted Critical
Publication of CN1139798C publication Critical patent/CN1139798C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

A multi-channel converter of optical fibre sensor for continuously measuring the solubility of medicine is composed of a shell, power cord, data transmission line, a power supply controller, an optical fibre transmitter and an optical fibre receiving switch. Said optical fibre transmitter consists of reflecting concave lens, light source, light-gathering lens and output optical fibre patchboard. Said optical fibre receiving switch comprises photomultiplier tube, single-channel switching disk and its driver, and input optical fibre patchboard. Its advantages are simple structure and more purposes.

Description

The Fibre Optical Sensor hyperchannel conversion device that is used for the METHOD FOR CONTINUOUS DETERMINATION drug dissolution
The present invention relates to the conversion equipment that a kind of Fibre Optical Sensor is used, be meant a kind of Fibre Optical Sensor that is used for METHOD FOR CONTINUOUS DETERMINATION drug dissolution hyperchannel conversion device especially.
At present, when utilizing Fibre Optical Sensor to measure the dissolution rate of medicine continuously, in real time, need do 6 parts of parallel experiments simultaneously, that is to say and to measure 6 parts of samples simultaneously, if adopt existing equipment to carry out said determination, just need with 6 cover light sources, 6 cover photoelectric commutator and six roots of sensation data lines, their connection and use be trouble very; And 6 complete equipments exist individual inconsistency, can strengthen the error of measurement; And because costing an arm and a leg of photoelectric commutator directly causes the cost of test to increase.
The object of the present invention is to provide a kind of measuring error little, the Fibre Optical Sensor that is used for METHOD FOR CONTINUOUS DETERMINATION drug dissolution hyperchannel conversion device that can a tractor serves several purposes.
The object of the present invention is achieved like this: a kind of Fibre Optical Sensor that is used for METHOD FOR CONTINUOUS DETERMINATION drug dissolution hyperchannel conversion device, comprise shell, power lead, data line and setting power control in the enclosure, it also includes and is separately positioned on emission chamber spaced apart from each other and indoor optical fiber emitter and the optical fiber receiving converter of reception cavity in the shell;
Wherein the optical fiber emitter be by be successively set on the reflective concave mirror of semisphere, light source, the optically focused convex lens on the indoor same axis of emission cavity and be arranged on the housing face-plate to have with above-mentioned axis be the center, the output optical fibre plugboard that is distributed in several output optical fibre jacks on the same circumference is formed;
The optical fiber receiving converter be by be successively set on the single channel switching rotating disk that has a through hole on photomultiplier on the indoor same axis of reception cavity, the card and be arranged on the housing face-plate to have with above-mentioned axis be the center, be distributed in the input optical fibre plugboard of several input optical fibre jacks on the same circumference, and the drive unit of single channel switching rotating disk is formed; Wherein input optical fibre jack and through hole are centroclinal setting with its axial line with photomultiplier all.
Because the present invention utilizes same light source to provide incident light source for the incident optical of multifiber sensor, and utilize same photomultiplier to provide opto-electronic conversion for the mirror based fiber optica of multifiber sensor, reduced since a plurality of same light source and photoelectric conversion device because of there being individual difference, and the error that causes, thereby improved the comparability of test figure; And use the present invention can realize simultaneously a plurality of differences being carried out real-time dynamic monitoring, thereby saved the expense of purchasing many cover light sources and photoelectric commutator, and easy to install and use, have the characteristics of a tractor serves several purposes.
Below in conjunction with drawings and Examples the present invention is further described:
Fig. 1 is a front view of the present invention
Fig. 2 is that the A-A of Fig. 1 is to the sectional structure synoptic diagram
Fig. 3 looks enlarged diagram for the master of single channel switching rotating disk in the present invention
Fig. 4 is the present invention's connection diagram in use
A kind of Fibre Optical Sensor that is used for METHOD FOR CONTINUOUS DETERMINATION drug dissolution hyperchannel conversion device, comprise shell 2, power lead 10, data line 11 and be arranged on power control 12 in the shell 2 that it also includes and is separately positioned on emission chambers 14 spaced apart from each other in the shell 2 and receives optical fiber emitter and optical fiber receiving converter in the chamber 13; Receiving chamber 13 is a lighttight darkroom.
The optical fiber emitter be by be successively set on the reflective concave mirror 15 of semisphere, light source 16, optically focused convex lens 17 on the same axis in the emission chamber 14 and be arranged on shell 2 panels to have with above-mentioned axis be the center, the output optical fibre plugboard 3 that is distributed in several output optical fibre jacks 4 on the same circumference is formed; During use, after the light that light source 16 sends is reflected by the reflective concave mirror 15 of semisphere, by becoming parallel light beam behind the optically focused convex lens 17, be radiated on the output optical fibre plugboard 3, for the incident optical 21 that is plugged on the Fibre Optical Sensor in the output optical fibre jack 4 22 on the output optical fibre plugboard 3 provides even, consistent incident light.
The optical fiber receiving converter be by be successively set on receive the single channel switching rotating disk 7 that has a through hole 8 in the chamber 13 on the photomultiplier 9 on the same axis, the card and be arranged on shell 2 panels to have with above-mentioned axis be the center, be distributed in the input optical fibre plugboard 1 of several input optical fibre jacks 5 on the same circumference, and the drive unit of single channel switching rotating disk 7 is formed; Wherein input optical fibre jack 5 and through hole 8 are centroclinal setting with its axial line with photomultiplier 9 all, like this, be plugged on after sample reflected light that the mirror based fiber optica 26 of the Fibre Optical Sensor in the input optical fibre jack 5 22 on the input optical fibre plugboard 1 sends passes through hole 8, can direct irradiation on photomultiplier 9.
The drive unit of single channel switching rotating disk 7 can be by motor 6, driving belt 20 and is arranged at respectively that belt pulley on single channel switching rotating disk axis 19 and motor 6 power output shaft forms; Its role is to drive single channel switching rotating disk 7 rotates, make on the single channel switching rotating disk 7 through hole 8 successively with input optical fibre plugboard 1 on a plurality of input optical fibre jacks 5 be on the same phase place, be plugged on the light that the many mirror based fiber opticas 26 on the input optical fibre plugboard 1 send and can be radiated on the photomultiplier 9 successively thereby make; Certainly, drive unit can also adopt other kind of drive, as gear drive etc.
In the through hole 8 on single channel switching rotating disk 7, can also be provided with an optical filter 18; Its role is to can the unwanted wavelength of filtering light.
As shown in Figure 4, when using the present invention to measure drug dissolution, at first will need the incident optical 21 on the Fibre Optical Sensor 22 of quantity to be plugged on respectively on output optical fibre plugboard 3 and the input optical fibre plugboard 1 by identical order, and data line 11 and computer will be connected with mirror based fiber optica 26; Again the probe on the Fibre Optical Sensor 22 25 is put into the beaker 23 of splendid attire sample 24 respectively; Energized then, at this moment, behind the reflection of the reflective concave mirror 15 of light process semisphere that light source 16 sends and the optically focused of optically focused convex lens 17, be radiated on the output optical fibre plugboard 3, and import on the probe 25 that is immersed in the sample 24 by the incident optical 21 of pegging graft thereon; The reflected light of sample 24 is transferred among the present invention on the optical fiber receiving converter by mirror based fiber optica 26, single channel switching rotating disk 7 rotates under the driving of the control of computer and motor 6, conducting is plugged on many mirror based fiber opticas 26 on the input optical fibre plugboard 1 and the path between the photomultiplier 9 respectively successively, thereby orderly, circulation receives the light signal that conversion different fiber sensor 22 is beamed back by its mirror based fiber optica 26.
The present invention also can be used for other and can use Fibre Optical Sensor to carry out the occasion that dynamic real-time is measured.

Claims (3)

1. Fibre Optical Sensor hyperchannel conversion device that is used for the METHOD FOR CONTINUOUS DETERMINATION drug dissolution, comprise shell (2), power lead (10), data line (11) and be arranged on the interior power control (12) of shell (2), it is characterized in that it also includes optical fiber emitter and the optical fiber receiving converter that is separately positioned in interior emission chamber spaced apart from each other (14) of shell (2) and the reception chamber (13);
Wherein the optical fiber emitter is to have with above-mentioned axis to be the center, to be distributed in output optical fibre plugboard (3) composition of several output optical fibre jacks (4) on the same circumference on shell (2) panel by being successively set on the reflective concave mirror of semisphere (15), light source (16), optically focused convex lens (17) on the same axis in emission chamber (14) and being arranged on;
The optical fiber receiving converter be by be successively set on receive the single channel switching rotating disk (7) that has a through hole (8) in the chamber (13) on the photomultiplier (9) on the same axis, the card and be arranged on shell (2) panel to have with above-mentioned axis be the center, be distributed in the input optical fibre plugboard (1) of several input optical fibre jacks (5) on the same circumference, and the drive unit of single channel switching rotating disk (7) is formed; Wherein input optical fibre jack (5) and through hole (8) are centroclinal setting with its axial line with photomultiplier (9) all.
2. the Fibre Optical Sensor that is used for METHOD FOR CONTINUOUS DETERMINATION drug dissolution hyperchannel conversion device according to claim 1, the drive unit that it is characterized in that single channel switching rotating disk (7) can and be arranged at single channel respectively by motor (6), driving belt (20) and transfer that belt pulley on rotating disk axis (19) and motor (6) power output shaft forms.
3. the Fibre Optical Sensor that is used for METHOD FOR CONTINUOUS DETERMINATION drug dissolution hyperchannel conversion device according to claim 1 is characterized in that can also being provided with an optical filter (18) in the through hole (8) on single channel switching rotating disk (7).
CNB011088346A 2001-03-01 2001-03-01 Multi-channel converter for optical fibre sensors to continuously measure solubility of medicine Expired - Fee Related CN1139798C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB011088346A CN1139798C (en) 2001-03-01 2001-03-01 Multi-channel converter for optical fibre sensors to continuously measure solubility of medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB011088346A CN1139798C (en) 2001-03-01 2001-03-01 Multi-channel converter for optical fibre sensors to continuously measure solubility of medicine

Publications (2)

Publication Number Publication Date
CN1309290A true CN1309290A (en) 2001-08-22
CN1139798C CN1139798C (en) 2004-02-25

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CNB011088346A Expired - Fee Related CN1139798C (en) 2001-03-01 2001-03-01 Multi-channel converter for optical fibre sensors to continuously measure solubility of medicine

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100456019C (en) * 2003-11-13 2009-01-28 吉林大学 Dissolving degree detector for continuously detecting multiple component medicine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100456019C (en) * 2003-11-13 2009-01-28 吉林大学 Dissolving degree detector for continuously detecting multiple component medicine

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CN1139798C (en) 2004-02-25

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Granted publication date: 20040225

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