CN1301121C - Medicine for curing toxuria - Google Patents

Abstract

The present invention relates to medicine for treating uraemia, which is prepared from the following raw material by weight proportions: 2 to 4 parts of ginseng, 20 to 50 parts of membranous milkvetch root, 10 to 20 parts of prepared rehmannia root, 5 to 15 parts of barbary wolfberry fruit, 3 to 10 parts of cassia bark, 2 to 15 parts of angelica, 3 to 10 parts of mirabilite, 30 to 60 parts of motherwort herb, 5 to 10 parts of twotooth achyranthes root and 1 to 2 parts of rhubarb. The medicine which is a granule preparation has the functions of spleen invigorating, qi replenishing, kidney warming, spleen strengthening, blood circulation activation, blood stasis dissipation, catharsis, toxin expulsion, toxic nitrogen reduction in hematuria, muscle and liver balancing, chronic renal failure control. The medicine is taken for 15 grams each time and for 2 times a day; the medicine is taken accompanied with warmed water on an empty stomach, and average time for taking the medicine is 3 months. Clinical observation shows that an effective rate is 84.7%; after the medicine is taken for 1 month, obvious effects are shown, namely that P is less than 0.05; however, after patients in a contrast group take Shenan medicine for 2 months, differences are still not obvious, namely that P is more than 0.05. The medicine for treating uraemia in the present invention has obvious curative effects on the reversion and the stabilization of illness states and the control of uremia progression, and has no toxic side effects.

Description

Treat uremic medicine

Technical field

The invention belongs to the field of Chinese medicines, relate to and a kind ofly reduce that hematuria poison nitrogen, flesh edema caused by disorder of the liver are flat, the uremic electuary of treatment of postponing chronic kidney function failure.

Background technology

Uremia is the common frdquently encountered disease of serious threat human body health, or even child how old also has this disease of suffering from.This disease is a kind of difficult disease, and the ill later stage need be carried out hemodialysis and be earned a bare living, and the required expense costliness of at every turn dialysing is that common people are difficult to bear.Take kidney peace weak curative effect in the former Therapeutic Method, side effect is big.

Summary of the invention

The objective of the invention is to overcome the deficiency that prior art exists, a kind of invigorating the spleen and replenishing QI that has is provided, warming the kidney and strengthening the spleen, blood circulation and removing stasis, purging FU-organs rush down turbid function, treatment uremia, hematuria poison nitrogen, flesh edema caused by disorder of the liver are flat to reduce, the curative effect of postponing chronic kidney function failure electuary preferably.

The objective of the invention is to be achieved by following technical proposals:

The uremic medicine of a kind of treatment is characterized in that it is to be made by following materials of weight proportions:

Radix Ginseng 2～4 Radixs Astragali 20～50 Radix Rehmanniae Preparata 10～20 Fructus Lycii 5～15

Cortex Cinnamomi 3～10 Radix Angelicae Sinensis 2～15 Natrii Sulfas 3～10 Herba Leonuris 30～60

Radix Achyranthis Bidentatae 5～10 Radix Et Rhizoma Rhei 1～2

The dosage form of aforesaid medicine is a dissolved granule.

Technical scheme of the present invention is based on motherland's medical science to uremic understanding and Therapeutic Principle, draw the elite in the research for many years, therefrom filter out suitable natural vegetable Chinese herbal medicine, prescription is scientific and reasonable, reuse Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata in the side, invigorating QI to consolidate the body surface resistance, poison holding life, warming and recuperating the spleen and kidney; The minister Radix Angelicae Sinensis, the strengthening the spleen blood circulation and removing stasis is mended tissue regeneration promoting blood; Assistant Fructus Lycii, Cortex Cinnamomi nourishing the kidney and liver, enhancing immunity, warming and recuperating the kidney-YANG makes Radix Achyranthis Bidentatae the kidney invigorating priming descending, controls dysuria; Radix Et Rhizoma Rhei, Natrii Sulfas can rush down turbid by purging FU-organs.The said medicine compatibility rationally can improve tonifying speen and tonifying kidney, warming the kidney to invigorate YANG, and blood circulation and removing stasis, purging FU-organs rush down turbid function.

The uremic medicine of treatment provided by the invention-uremic health, through the preuremic stage patient clinical observation, have significant curative effect than the treatment of present technology kidney peace, obvious reverse is arranged, stablize the state of an illness, delay disease and make progress, and find no toxic and side effects.On average taking medicine 3 months, is 84.7% through the clinical observation obvious effective rate, medication 1 month, just there were significant differences P＜0.05; And kidney peace matched group was taken medicine the still not obvious P of difference＞0.05 2 months.

Function with cure mainly: invigorating the spleen and replenishing QI, warming the kidney and strengthening the spleen, blood circulation and removing stasis, purging FU-organs rush down turbid.Be applicable to uremia, can reduce hematuria poison nitrogen, the flesh edema caused by disorder of the liver is flat, the depletion of delaying chronic kidney merit.

Usage and consumption: oral 15g/ time, 1 twice-daily, early, late (medicine) being taken before meal uses.

Above-mentioned treatment uremia, as experimental group, taking the kidney peace with 60 examples by former Therapeutic Method is matched group, respectively through clinical observation through 180 routine uremic patients.1 month is 1 course of treatment, average medication 3 months, and clinical symptoms, Signs and lab testing obviously improve, and total effective rate is 84.7%.With kidney peace group curative effect comparision symptom, Signs is partly used X ²Check, laboratory data-check just had significant difference P value＜0.05 in 1 month after the experimental group medication; And treatment of control group after 2 months difference remarkable P value＞0.05 still.The uremic medicine of treatment of the present invention has the tangible reverse and the stable state of an illness, delays the curative effect of uremia's progress, does not find toxic side effect.

The specific embodiment

Now in conjunction with the embodiments technical scheme of the present invention is further described.

Embodiment

1. take by weighing the raw material (kg) that each embodiment needs by following proportioning

	Radix Ginseng	The Radix Astragali	Radix Rehmanniae Preparata	Fructus Lycii	Cortex Cinnamomi	Radix Angelicae Sinensis	Natrii Sulfas	Herba Leonuri	Radix Achyranthis Bidentatae	Radix Et Rhizoma Rhei
											Embodiment 1	2	20	10	5	3	2	3	30	5	1
Embodiment 2	3	35	15	10	6.5	8.5	6.5	45	7.5	1.5
											Embodiment 3	4	50	20	15	10	15	10	60	10	2

2, production method

(1) with the above-mentioned Radix Astragali, Radix Rehmanniae Preparata, Herba Leonuri and Radix Achyranthis Bidentatae four flavor raw materials, select clean, remove impurity after, take by weighing by embodiment 1～3 needed raw material in the above-mentioned table, adding its consumption of water is 3 times of material quantities, decocts each 3 hours 3 times, three times filtrate is mixed through being condensed into the thick paste shape, add 3 times of amount ethanol, static 48 hours, filtrate recycling ethanol gets its extractum, and is standby;

(2) remaining six kinds of raw material Radix Ginsengs, Radix Angelicae Sinensis, Fructus Lycii, Cortex Cinnamomi, Radix Et Rhizoma Rhei and Natrii Sulfas are selected, Ex-all impurity with ordinary water flush away earth, after 50～70 ℃ of oven dry, mixes and pulverizes (slowly pulverizing) to 100 order fineness;

(3) system soft material: extractum and raw material medicated powder, xylitol, starch are made soft material after mixing;

(4) granulate: the above-mentioned soft material that makes through granulating and crossing 10 mesh sieves, is drying to obtain in 50 ℃ of hothouses;

(5) granulate: an above-mentioned dry back material is sieved, get by No. 4 sieves, and can not be by whole granule mixings of No. 1 sieve, sampling inspection;

(6) packing: through chemically examining qualified granule, in aseptic subpackaged indoor packing, press the loading amount pack of 15g/ bag, and press the loading amount dress box (or by 12 pouches/sack loading amount pack) of 15g * 12 bag/box, vanning is put in storage then.

The uremic medicament selection of the above-mentioned treatment that makes is an electuary.Powder is difficult to make in the raw material effective ingredient more to give full play to drug effect, takes the decocting and concentrating extraction method, can give full play to its drug effect, to reach best therapeutic effect.Above-mentioned electuary outward appearance is sepia or yellowish-brown, sweet and slightly bitter taste.Add xylitol during the system soft material, make to be applicable to simultaneously that also suffering from diabetics takes by the uremic uremic health of treatment provided by the invention medicine.

Claims (2)

1, the uremic medicine of a kind of treatment is characterized in that it is to be made by following materials of weight proportions

Radix Ginseng 2～4 Radixs Astragali 20～50 Radix Rehmanniae Preparata 10～20 Fructus Lycii 5～15

Cortex Cinnamomi 3～10 Radix Angelicae Sinensis 2～15 Natrii Sulfas 3～10 Herba Leonuris 30～60

Radix Achyranthis Bidentatae 5～10 Radix Et Rhizoma Rhei 1～2.

2, medicine according to claim 1, the dosage form that it is characterized in that described medicine is a dissolved granule.