CN1301121C - Medicine for curing toxuria - Google Patents
Medicine for curing toxuria Download PDFInfo
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- CN1301121C CN1301121C CNB031114970A CN03111497A CN1301121C CN 1301121 C CN1301121 C CN 1301121C CN B031114970 A CNB031114970 A CN B031114970A CN 03111497 A CN03111497 A CN 03111497A CN 1301121 C CN1301121 C CN 1301121C
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- 239000003814 drug Substances 0.000 title claims abstract description 26
- 229940079593 drug Drugs 0.000 title description 4
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- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 6
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- 235000008434 ginseng Nutrition 0.000 claims abstract description 6
- 241000208340 Araliaceae Species 0.000 claims description 5
- RSIJVJUOQBWMIM-UHFFFAOYSA-L sodium sulfate decahydrate Chemical compound O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O RSIJVJUOQBWMIM-UHFFFAOYSA-L 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 241000545442 Radix Species 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims description 2
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- 230000000694 effects Effects 0.000 abstract description 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract description 8
- 208000037157 Azotemia Diseases 0.000 abstract description 8
- 210000000952 spleen Anatomy 0.000 abstract description 8
- 239000002994 raw material Substances 0.000 abstract description 7
- 208000009852 uremia Diseases 0.000 abstract description 6
- 238000010792 warming Methods 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 5
- 210000004185 liver Anatomy 0.000 abstract description 5
- 239000009636 Huang Qi Substances 0.000 abstract description 4
- 230000006870 function Effects 0.000 abstract description 4
- 208000006750 hematuria Diseases 0.000 abstract description 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract description 4
- 238000005728 strengthening Methods 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 3
- 210000004369 blood Anatomy 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 241000427159 Achyranthes Species 0.000 abstract 1
- 244000192528 Chrysanthemum parthenium Species 0.000 abstract 1
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- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
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- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 244000071493 Iris tectorum Species 0.000 abstract 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 abstract 1
- 244000241838 Lycium barbarum Species 0.000 abstract 1
- 235000015459 Lycium barbarum Nutrition 0.000 abstract 1
- 235000015468 Lycium chinense Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
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- 208000020832 chronic kidney disease Diseases 0.000 abstract 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 abstract 1
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- 239000010446 mirabilite Substances 0.000 abstract 1
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- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 2
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Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to medicine for treating uraemia, which is prepared from the following raw material by weight proportions: 2 to 4 parts of ginseng, 20 to 50 parts of membranous milkvetch root, 10 to 20 parts of prepared rehmannia root, 5 to 15 parts of barbary wolfberry fruit, 3 to 10 parts of cassia bark, 2 to 15 parts of angelica, 3 to 10 parts of mirabilite, 30 to 60 parts of motherwort herb, 5 to 10 parts of twotooth achyranthes root and 1 to 2 parts of rhubarb. The medicine which is a granule preparation has the functions of spleen invigorating, qi replenishing, kidney warming, spleen strengthening, blood circulation activation, blood stasis dissipation, catharsis, toxin expulsion, toxic nitrogen reduction in hematuria, muscle and liver balancing, chronic renal failure control. The medicine is taken for 15 grams each time and for 2 times a day; the medicine is taken accompanied with warmed water on an empty stomach, and average time for taking the medicine is 3 months. Clinical observation shows that an effective rate is 84.7%; after the medicine is taken for 1 month, obvious effects are shown, namely that P is less than 0.05; however, after patients in a contrast group take Shenan medicine for 2 months, differences are still not obvious, namely that P is more than 0.05. The medicine for treating uraemia in the present invention has obvious curative effects on the reversion and the stabilization of illness states and the control of uremia progression, and has no toxic side effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to and a kind ofly reduce that hematuria poison nitrogen, flesh edema caused by disorder of the liver are flat, the uremic electuary of treatment of postponing chronic kidney function failure.
Background technology
Uremia is the common frdquently encountered disease of serious threat human body health, or even child how old also has this disease of suffering from.This disease is a kind of difficult disease, and the ill later stage need be carried out hemodialysis and be earned a bare living, and the required expense costliness of at every turn dialysing is that common people are difficult to bear.Take kidney peace weak curative effect in the former Therapeutic Method, side effect is big.
Summary of the invention
The objective of the invention is to overcome the deficiency that prior art exists, a kind of invigorating the spleen and replenishing QI that has is provided, warming the kidney and strengthening the spleen, blood circulation and removing stasis, purging FU-organs rush down turbid function, treatment uremia, hematuria poison nitrogen, flesh edema caused by disorder of the liver are flat to reduce, the curative effect of postponing chronic kidney function failure electuary preferably.
The objective of the invention is to be achieved by following technical proposals:
The uremic medicine of a kind of treatment is characterized in that it is to be made by following materials of weight proportions:
Radix Ginseng 2～4 Radixs Astragali 20～50 Radix Rehmanniae Preparata 10～20 Fructus Lycii 5～15
Cortex Cinnamomi 3～10 Radix Angelicae Sinensis 2～15 Natrii Sulfas 3～10 Herba Leonuris 30～60
Radix Achyranthis Bidentatae 5～10 Radix Et Rhizoma Rhei 1～2
The dosage form of aforesaid medicine is a dissolved granule.
Technical scheme of the present invention is based on motherland's medical science to uremic understanding and Therapeutic Principle, draw the elite in the research for many years, therefrom filter out suitable natural vegetable Chinese herbal medicine, prescription is scientific and reasonable, reuse Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata in the side, invigorating QI to consolidate the body surface resistance, poison holding life, warming and recuperating the spleen and kidney; The minister Radix Angelicae Sinensis, the strengthening the spleen blood circulation and removing stasis is mended tissue regeneration promoting blood; Assistant Fructus Lycii, Cortex Cinnamomi nourishing the kidney and liver, enhancing immunity, warming and recuperating the kidney-YANG makes Radix Achyranthis Bidentatae the kidney invigorating priming descending, controls dysuria; Radix Et Rhizoma Rhei, Natrii Sulfas can rush down turbid by purging FU-organs.The said medicine compatibility rationally can improve tonifying speen and tonifying kidney, warming the kidney to invigorate YANG, and blood circulation and removing stasis, purging FU-organs rush down turbid function.
The uremic medicine of treatment provided by the invention-uremic health, through the preuremic stage patient clinical observation, have significant curative effect than the treatment of present technology kidney peace, obvious reverse is arranged, stablize the state of an illness, delay disease and make progress, and find no toxic and side effects.On average taking medicine 3 months, is 84.7% through the clinical observation obvious effective rate, medication 1 month, just there were significant differences P＜0.05; And kidney peace matched group was taken medicine the still not obvious P of difference＞0.05 2 months.
Function with cure mainly: invigorating the spleen and replenishing QI, warming the kidney and strengthening the spleen, blood circulation and removing stasis, purging FU-organs rush down turbid.Be applicable to uremia, can reduce hematuria poison nitrogen, the flesh edema caused by disorder of the liver is flat, the depletion of delaying chronic kidney merit.
Usage and consumption: oral 15g/ time, 1 twice-daily, early, late (medicine) being taken before meal uses.
Above-mentioned treatment uremia, as experimental group, taking the kidney peace with 60 examples by former Therapeutic Method is matched group, respectively through clinical observation through 180 routine uremic patients.1 month is 1 course of treatment, average medication 3 months, and clinical symptoms, Signs and lab testing obviously improve, and total effective rate is 84.7%.With kidney peace group curative effect comparision symptom, Signs is partly used X
2Check, laboratory data-check just had significant difference P value＜0.05 in 1 month after the experimental group medication; And treatment of control group after 2 months difference remarkable P value＞0.05 still.The uremic medicine of treatment of the present invention has the tangible reverse and the stable state of an illness, delays the curative effect of uremia's progress, does not find toxic side effect.
The specific embodiment
Now in conjunction with the embodiments technical scheme of the present invention is further described.
Embodiment
1. take by weighing the raw material (kg) that each embodiment needs by following proportioning
| Radix Ginseng | The Radix Astragali | Radix Rehmanniae Preparata | Fructus Lycii | Cortex Cinnamomi | Radix Angelicae Sinensis | Natrii Sulfas | Herba Leonuri | Radix Achyranthis Bidentatae | Radix Et Rhizoma Rhei | |
| Embodiment 1 | 2 | 20 | 10 | 5 | 3 | 2 | 3 | 30 | 5 | 1 |
| Embodiment 2 | 3 | 35 | 15 | 10 | 6.5 | 8.5 | 6.5 | 45 | 7.5 | 1.5 |
| Embodiment 3 | 4 | 50 | 20 | 15 | 10 | 15 | 10 | 60 | 10 | 2 |
2, production method
(1) with the above-mentioned Radix Astragali, Radix Rehmanniae Preparata, Herba Leonuri and Radix Achyranthis Bidentatae four flavor raw materials, select clean, remove impurity after, take by weighing by embodiment 1～3 needed raw material in the above-mentioned table, adding its consumption of water is 3 times of material quantities, decocts each 3 hours 3 times, three times filtrate is mixed through being condensed into the thick paste shape, add 3 times of amount ethanol, static 48 hours, filtrate recycling ethanol gets its extractum, and is standby;
(2) remaining six kinds of raw material Radix Ginsengs, Radix Angelicae Sinensis, Fructus Lycii, Cortex Cinnamomi, Radix Et Rhizoma Rhei and Natrii Sulfas are selected, Ex-all impurity with ordinary water flush away earth, after 50～70 ℃ of oven dry, mixes and pulverizes (slowly pulverizing) to 100 order fineness;
(3) system soft material: extractum and raw material medicated powder, xylitol, starch are made soft material after mixing;
(4) granulate: the above-mentioned soft material that makes through granulating and crossing 10 mesh sieves, is drying to obtain in 50 ℃ of hothouses;
(5) granulate: an above-mentioned dry back material is sieved, get by No. 4 sieves, and can not be by whole granule mixings of No. 1 sieve, sampling inspection;
(6) packing: through chemically examining qualified granule, in aseptic subpackaged indoor packing, press the loading amount pack of 15g/ bag, and press the loading amount dress box (or by 12 pouches/sack loading amount pack) of 15g * 12 bag/box, vanning is put in storage then.
The uremic medicament selection of the above-mentioned treatment that makes is an electuary.Powder is difficult to make in the raw material effective ingredient more to give full play to drug effect, takes the decocting and concentrating extraction method, can give full play to its drug effect, to reach best therapeutic effect.Above-mentioned electuary outward appearance is sepia or yellowish-brown, sweet and slightly bitter taste.Add xylitol during the system soft material, make to be applicable to simultaneously that also suffering from diabetics takes by the uremic uremic health of treatment provided by the invention medicine.
Claims (2)
1, the uremic medicine of a kind of treatment is characterized in that it is to be made by following materials of weight proportions
Radix Ginseng 2～4 Radixs Astragali 20～50 Radix Rehmanniae Preparata 10～20 Fructus Lycii 5～15
Cortex Cinnamomi 3～10 Radix Angelicae Sinensis 2～15 Natrii Sulfas 3～10 Herba Leonuris 30～60
Radix Achyranthis Bidentatae 5～10 Radix Et Rhizoma Rhei 1～2.
2, medicine according to claim 1, the dosage form that it is characterized in that described medicine is a dissolved granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031114970A CN1301121C (en) | 2003-04-16 | 2003-04-16 | Medicine for curing toxuria |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031114970A CN1301121C (en) | 2003-04-16 | 2003-04-16 | Medicine for curing toxuria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1456195A CN1456195A (en) | 2003-11-19 |
| CN1301121C true CN1301121C (en) | 2007-02-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031114970A Expired - Fee Related CN1301121C (en) | 2003-04-16 | 2003-04-16 | Medicine for curing toxuria |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1301121C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028897B (en) * | 2010-12-08 | 2012-02-15 | 山西医科大学第一医院 | Chinese patent drug for treating glomerular hematuria and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1192928A (en) * | 1997-03-11 | 1998-09-16 | 凉城县鸿茅酒厂 | Production process for medicinal liquor |
| CN1334118A (en) * | 2001-08-09 | 2002-02-06 | 刘广斌 | Chinese medicine for treating uremia |
| CN1398621A (en) * | 2002-09-10 | 2003-02-26 | 袁东林 | Kidney-invigorating capsule and its prepn |
-
2003
- 2003-04-16 CN CNB031114970A patent/CN1301121C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1192928A (en) * | 1997-03-11 | 1998-09-16 | 凉城县鸿茅酒厂 | Production process for medicinal liquor |
| CN1334118A (en) * | 2001-08-09 | 2002-02-06 | 刘广斌 | Chinese medicine for treating uremia |
| CN1398621A (en) * | 2002-09-10 | 2003-02-26 | 袁东林 | Kidney-invigorating capsule and its prepn |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1456195A (en) | 2003-11-19 |
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| C14 | Grant of patent or utility model | ||
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Owner name: ZHU BAI Free format text: FORMER OWNER: JILIN CENTER HOSPITAL Effective date: 20070608 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20070608 Address after: 132001 No. 4, Nanjing street, Jilin, Jilin Patentee after: Zhu Bai Address before: 132001 No. 4, Nanjing street, Jilin, Jilin Patentee before: Jilin City Center Hospital |
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Granted publication date: 20070221 Termination date: 20130416 |