CN1299619A - Protein beverage with the function of reducing cholesterol - Google Patents
Protein beverage with the function of reducing cholesterol Download PDFInfo
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- CN1299619A CN1299619A CN 00130861 CN00130861A CN1299619A CN 1299619 A CN1299619 A CN 1299619A CN 00130861 CN00130861 CN 00130861 CN 00130861 A CN00130861 A CN 00130861A CN 1299619 A CN1299619 A CN 1299619A
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- phytosterol
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Abstract
The protein beverage for reducing serum cholesterol comprises 0.1-10% (wt%) of phytosterol aliphatic ester which is made up by phtosterol and aliphatic acid through the process of esterification, in which the phytosterol is the mixture of beta-sitosterol, campesterol, stigmasterol and other natural sterol, and its aliphatic acid is one of C2-C22 aliphatic acids or their mixed aliphatic acid. The protein beverage containing above 0.75g of phytosterol aliphatic ester can be taken in by adult to attain the goal of reducing cholesterol to reduce incidence rate and death rate of coronary heart disease.
Description
The present invention relates to a kind of beverage, specifically relate to a kind of protein beverage that reduces the cholesterol effect that has.
In many countries, the angiocardiopathy death rate accounts for the front three of all disease death rates, accounts for 30～50% of death rate sum.Angiocardiopathy is ratio in the dead sum of China, by rising to till now more than 50% 20% of the fifties.Coronary heart disease is disease common, the most serious in the angiocardiopathy, and the death rate is also the highest.Scientific experimentation shows, and elevated cholesterol and high LDL (low-density lipoprotein) cholesterol are to cause the hazards of coronary heart disease.Scientific research also shows to have only the intervention by extreme harshness, particularly reduces smoking capacity and reduces the high plasma cholesterol level conscientiously by the meals adjustment, and the death rate of coronary heart disease just has significant reduction.
The purpose of this invention is to provide a kind of protein beverage that reduces the serum cholesterol effect that has, can effectively reduce the high plasma cholesterol level after drinking this beverage, thereby reduce the incidence and the death rate of coronary heart disease.
For reaching above-mentioned purpose, the technical solution used in the present invention is: the phytosterol fatty acid ester that adds 0.1～10% (weight) in protein beverage.Described phytosterol fatty acid ester is to be made by esterification by phytosterol and aliphatic acid, and wherein phytosterol is the mixture of cupreol, campesterol, stigmasterol and other natural sterol; Aliphatic acid is C
2～C
22One or more fatty acid mixeds in the aliphatic acid.It can be a kind of liquid beverage that the present invention has the protein beverage that reduces the cholesterol effect, as soymilk, milky cocoa, peanut milk, milk or their mixture, also can be a kind of solid beverage, as soymilk powder, milk powder or their mixture.Because the phytosterol fatty acid ester is that oil soluble material is water insoluble, therefore need it be distributed in the various protein beverages with suitable dispersant.These dispersants can be molecular distillation monoglyceride, sucrose fatty ester, polyglyceryl fatty acid ester, and one or more mixtures in the arm protein acid sodium also can adopt other edible dispersant.Because aliphatic acid mainly is unrighted acid in this phytosterol fatty acid ester, therefore, adding suitable antioxidant in protein beverage needs, as adds a certain amount of vitamin C or vitamin E.
Mechanism of the present invention and characteristics: phytosterol is the solvent of all plants, and their functions in plant are equivalent to the effect of cholesterol in the mammal.The abundantest phytosterol is cupreol, campesterol and stigmasterol in the plant.The structure of these phytosterols and cholesterol are extremely similar, and they only there are differences on the side chain of molecular skeleton.From nineteen fifties, people had recognized already that phytosterol had the effect that reduces serum cholesterol level.Even when using than low dosage number every day gram, they also can effectively reduce the absorbability of biliary cholesterol and dietary cholesterol exposure, thereby reduce total and LDL cholesterol level in the serum.People still not really understand for the restricted cholesterol absorption mechanism, but according to inferring, phytosterol is replaced out the cholesterol in the micellar phase, thereby has stoped being absorbed of cholesterol.Phytosterol has been considered to reduce the safe material of serum cholesterol concentration, and this gives the credit to them is natural constituents of plant fat and vegetable oil.Phytosterol can be easily from edible vegetable oil, goes out in thing or the paper industry tall oil to extract as the deodorization gold-plating of soybean oil, vegetable seed wet goods, all has suitability for industrialized production at present.The phytosterol fatty acid ester is a kind of fatty acid ester blends that phytosterol and aliphatic acid form by chemical reaction.Nearest studies show that, compares with free phytosterol, and the phytosterin ester of aliphatic acid form can more effectively reduce serum cholesterol level.What deserves to be mentioned is that the phytostanol fatty acid ester is different from phytosterol fatty acid ester of the present invention.Phytostanol is that phytosterol makes by catalytic hydrogenation.Make catalyst owing to need to use precious metal palladium, the production cost of phytostanol fatty acid ester will be higher than the phytosterol fatty acid ester, and clinical testing shows, per day for adults be as long as taking in the above phytosterol fatty acid ester of 1.3g can reach and reduce the cholesterol purpose, and if absorption be that the phytostanol fatty acid ester just needs 3.4g.
The phytosterol fatty acid ester is used the existing report of patent in food.As United States Patent (USP) 3,751,569 have described the method for just enjoying interpolation phytosterol fatty acid ester in the oil of preparing food.The purpose of this method is the cholesterol levels that reduces in the human serum.United States Patent (USP) 5,270,041 has described the method that the phytosterol fatty acid ester is applied to oncotherapy, and this patent is referred to above-mentioned substance simultaneously may be as the purposes of diet and food additives, but the data of any relevant serum cholesterol reduction effect are not provided.In fact, all about the application patent and the actual food that all only limits to be rich in fat that uses of phytosterol fatty acid ester, as margarine, vegetable oil.The phytosterol fatty acid ester is applied to the various beverages that are rich in high protein not to be reported as yet.The food that is rich in animal protein contains a certain amount of cholesterol and saturated fat usually, therefore, takes in a large amount of animal proteins for a long time, causes that easily cholesterol levels raises.And on the other hand, vegetable protein such as soybean protein have the effect of the serum cholesterol of reduction, but this effect is a prerequisite to take in the 25g soybean protein every day.In fact, common eating habit all can not guarantee can take in the protein of this quantity every day.The every 100ml of soymilk on the market is soybean protein-containing 2～3g only.If per day for adults can only take in the 15g soybean protein at most, and this is far from reaching above-mentioned dosage requirement to drink 500ml.Therefore, in all kinds of protein beverages, add the phytosterol fatty acid ester, except can solving the cholesterol rising problem that animal protein itself causes, but the also norcholesterol effect of fortification of plants albumen.The present invention finds that first phytosterol fatty acid ester and soybean protein are having good synergy aspect the reduction serum cholesterol, be that to take in 0.75g phytosterol fatty acid ester and 10g soybean protein every day be suitable with taking in the 1.3g phytosterol in the effect that reduces serum total cholesterol level, and take in 0.75g phytosterol fatty acid ester separately or the 10g soybean protein does not all have tangible norcholesterol effect.
Describe the present invention in detail below in conjunction with embodiment.
Embodiment 1
A kind of soymilk formulations with the effect of reduction cholesterol is:
Extract of soybean 8g (wherein soybean protein-containing 3.3g)
White sugar 6g
Soybean oil 2g
Phytosterol fatty acid ester 0.3g
Monoglyceride 0.2g
Sodium Caseinate 0.3g
Sucrose ester (HLB11) 0.2g
V
EIn right amount
Water is made into 100ml
Wherein, adopt the quality index of phytosterol fatty acid ester to be:
Phytosterol fatty acid ester content (weight): 96%
Phytosterol mainly forms and content (weight) is: cupreol 50%, campesterol 28%, stigmasterol 18%
Aliphatic acid is formed and content (weight) is: C
16: 0 6.5%, C
18: 0 5.1%, C
18: 1 65.1%, C
18: 2 22.7%
Embodiment 2
A kind of peanut milk (solid beverage) prescription with the effect of reduction cholesterol is:
Peanut extract 30g
Milk powder 30g
White sugar 25g
Microcapsules phytosterol fatty acid ester 15g
V
E, VC is an amount of
Essence is an amount of
Wherein, adopt the quality index of phytosterol fatty acid ester to be:
Phytosterol fatty acid ester content (weight): 40%
Phytosterol mainly forms and content (weight) is: cupreol 50%, campesterol 28%, stigmasterol 18%
Aliphatic acid is formed and content (weight) is: C
16: 0 6.5%, C
18: 0 5.1%, C
18: 1 65.1%, C
18: 2 22.7%
Embodiment 3
A kind of milk formulas with the effect of reduction cholesterol is:
Milk powder 12g
Monoglyceride 0.1g
Sucrose ester 0.1g
Phytosterol fatty acid ester 0.45g
V
EIn right amount
Water is made into 100ml
Wherein, adopt the quality index of phytosterol fatty acid ester to be:
Phytosterol mainly forms and content (weight) is: cupreol 50%, campesterol 28%, stigmasterol 18%
Aliphatic acid is formed and content (weight) is: C
16: 0 6.5%, C
18: 0 5.1%, C
18: 1 65.1%, C
18: 2 22.7%
Application Example 1
The test group material is selected from the soymilk that makes by embodiment 1 method, drinks 300ml for each person every day, is equivalent to take in every day 0.75g phytosterol fatty acid ester and 10g soybean protein.Control group 1 is taken in the common soymilk of 300ml for each person every day, promptly takes in about 10g soybean protein every day, and control group is taken in 1.3g phytosterol (capsule form) 2 every days.(T-CHOL is taken in 300ml soymilk average 6.01 ± 0.14mmol/L) every days, and edible is at random for 36 aspirations and the healthy women of free living.After taking for 5 weeks, measure serum total cholesterol content.
Table 1 take 5 week back total cholesterol density of serum (mmol/L, n:12)
| Control group 1 | Control group 2 | Test group | |
| T-CHOL | ????6.21±0.16 | ????5.64±0.13 * | ????5.61±0.17 * |
*P＜0.05
Table 1 data show, test group is taken in 0.75g phytosterol and 10g soybean protein every day and taken in 1.3g phytosterol (control group 2) separately and for reducing serum total cholesterol level statistical significance is arranged all.(P＜0.05), and both effects are suitable.Do not reduce the cholesterol effect and take in 10g soybean protein (control group 1) separately.This explanation, phytosterol fatty acid ester and soybean protein are having synergy aspect the reduction serum cholesterol level.In soymilk, add the phytosterol fatty acid ester,, equally also can obtain satisfied reduction cholesterol effect even reduce the phytosterol consumption.
Claims (10)
1, a kind of protein beverage with the effect of reduction cholesterol is characterized in that containing in this protein beverage 0.1～10% (weight) phytosterol fatty acid ester.
2, the protein beverage with the effect of reduction cholesterol as claimed in claim 1 is characterized in that described phytosterol fatty acid ester is to be made by esterification by phytosterol and aliphatic acid.
3, the protein beverage with the effect of reduction cholesterol as claimed in claim 2 is characterized in that described phytosterol is the mixture of cupreol, campesterol, stigmasterol and other natural sterol.
4, the protein beverage with the effect of reduction cholesterol as claimed in claim 2 is characterized in that described aliphatic acid is C
2～C
22One or more fatty acid mixeds in the aliphatic acid.
5, as each described protein beverage with the effect of reduction cholesterol of claim 1～4, it is characterized in that this protein beverage is a kind of liquid beverage, described liquid beverage is soymilk, milky cocoa, peanut milk, milk or their mixture.
6, as each described protein beverage with the effect of reduction cholesterol of claim 1～4, it is characterized in that this protein beverage is a kind of solid beverage, described solid beverage is soymilk powder, cocoa milk powder, peanut milk powder, milk powder or their mixture.
7, the protein beverage with the effect of reduction cholesterol as claimed in claim 1 is characterized in that containing dispersant in this protein beverage.
8, as claimed in claim 7 have a protein beverage that reduces the cholesterol effect, it is characterized in that described dispersant is one or more the mixture in molecular distillation monoglyceride, sucrose fatty ester, polyglyceryl fatty acid ester or the arm protein acid sodium.
9, the protein beverage with the effect of reduction cholesterol as claimed in claim 1 is characterized in that containing antioxidant in this protein beverage.
10, the protein beverage with the effect of reduction cholesterol as claimed in claim 1 is characterized in that described antioxidant is vitamin C or vitamin E.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00130861 CN1299619A (en) | 2000-12-18 | 2000-12-18 | Protein beverage with the function of reducing cholesterol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00130861 CN1299619A (en) | 2000-12-18 | 2000-12-18 | Protein beverage with the function of reducing cholesterol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1299619A true CN1299619A (en) | 2001-06-20 |
Family
ID=4594365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00130861 Pending CN1299619A (en) | 2000-12-18 | 2000-12-18 | Protein beverage with the function of reducing cholesterol |
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|---|---|
| CN (1) | CN1299619A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101248876B (en) * | 2008-03-20 | 2011-08-31 | 杭州娃哈哈集团有限公司 | Norcholesterol health care drink |
| CN102271536A (en) * | 2009-01-26 | 2011-12-07 | 拉伊西奥营养有限公司 | Beverage lowering serum cholesterol |
| CN103393072A (en) * | 2005-11-23 | 2013-11-20 | 可口可乐公司 | High-potency sweetener composition with phytosterol and composition sweetened therewith |
| CN103393063A (en) * | 2005-11-23 | 2013-11-20 | 可口可乐公司 | Natural high-potency sweetener composition with improved temporal profile and/or flavor profile, method for formulation, and uses |
| CN101795580B (en) * | 2007-07-25 | 2014-09-24 | 拉伊西奥营养有限公司 | A beverage and a method for preparation thereof |
| WO2015124083A1 (en) * | 2014-02-24 | 2015-08-27 | 郑鉴忠 | Beverage dissolved with phytosterol and production method therefor |
| US9179690B2 (en) | 2003-04-22 | 2015-11-10 | Raisio Nutrition Ltd. | Edible product with masked bitter, sour and/or astringent taste |
| CN105432793A (en) * | 2010-02-06 | 2016-03-30 | 考格尼斯知识产权管理有限责任公司 | Drink |
-
2000
- 2000-12-18 CN CN 00130861 patent/CN1299619A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9179690B2 (en) | 2003-04-22 | 2015-11-10 | Raisio Nutrition Ltd. | Edible product with masked bitter, sour and/or astringent taste |
| CN103393072A (en) * | 2005-11-23 | 2013-11-20 | 可口可乐公司 | High-potency sweetener composition with phytosterol and composition sweetened therewith |
| CN103393071A (en) * | 2005-11-23 | 2013-11-20 | 可口可乐公司 | High-potency sweetener composition with phytosterol and compositions sweetened therewith |
| CN103393063A (en) * | 2005-11-23 | 2013-11-20 | 可口可乐公司 | Natural high-potency sweetener composition with improved temporal profile and/or flavor profile, method for formulation, and uses |
| CN101795580B (en) * | 2007-07-25 | 2014-09-24 | 拉伊西奥营养有限公司 | A beverage and a method for preparation thereof |
| CN101248876B (en) * | 2008-03-20 | 2011-08-31 | 杭州娃哈哈集团有限公司 | Norcholesterol health care drink |
| CN102271536A (en) * | 2009-01-26 | 2011-12-07 | 拉伊西奥营养有限公司 | Beverage lowering serum cholesterol |
| US9295267B2 (en) | 2009-01-26 | 2016-03-29 | Raisio Nutrition Ltd | Beverage lowering serum cholesterol |
| CN105432793A (en) * | 2010-02-06 | 2016-03-30 | 考格尼斯知识产权管理有限责任公司 | Drink |
| WO2015124083A1 (en) * | 2014-02-24 | 2015-08-27 | 郑鉴忠 | Beverage dissolved with phytosterol and production method therefor |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |