CN1293990A - Medicine 'Changlongdan' - Google Patents
Medicine 'Changlongdan' Download PDFInfo
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- CN1293990A CN1293990A CN 99115605 CN99115605A CN1293990A CN 1293990 A CN1293990 A CN 1293990A CN 99115605 CN99115605 CN 99115605 CN 99115605 A CN99115605 A CN 99115605A CN 1293990 A CN1293990 A CN 1293990A
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- medicine
- changlongdan
- radix
- rhizoma acori
- acori graminei
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Abstract
A Chinese patent medicine in the form of capsules for treating senile dementia is prepared from 8 Chinese-medicinal materials including grass-leaved sweetflag rhizome, earthworm, epimedium, dodder seed, etc through polverizing notoginseng, distilling out volatile oil from grass-leaved sweetflag rhizome, alcohol extraction of red sage root and polygala root, mixing others with dregs of grass-leaved sweetflag rhizome, decocting, filter, concentrating, mixing, granulating and loading in capsules. Its advantages is no obvious toxin.
Description
The present invention relates to a kind of Chinese patent medicine, is a kind of Chinese patent medicine for the treatment of senile dementia.
The old people is because dementia is easily suffered from the influence of naturally-aged and pathological factor, and effective control of senile dementia is the difficult problem of present geriatrics and spiritual neuromedicine.Mostly the western medical treatment that this is sick is the psychostimulant of application cerebral vasodilator, brain metabolism improving medicine, nootropics, calcium antagonist and medium action intensity etc.But uncertain therapeutic efficacy is cut, and side effect is bigger, and costs an arm and a leg.The traditional Chinese medical science thinks that function day by day fails, and makes easily clearly that key is subjected to cover, sudden inspiration is slow-witted blunt, deficiency of kidney-essence is not enough for morbidity this, and expectorant stasis of blood resistance key is morbific key.Existing Chinese medicine prevention senile dementia, how from the kidney invigorating, eliminate the phlegm or the treatment aspect medication of blood stasis dispelling but simple tonify deficiency, eliminating evil, always unsatisfactory curative effect.
Purpose of the present invention is to provide a kind of Chinese medicine medicine ' Changlongdan ' for the treatment of both the principal and secondary aspects of a disease from aspects such as kidney tonifying, essence replenishing benefit marrow, blood circulation promoting and blood stasis dispelling, waking up the patient from unconsciousness by dissipating phlegm, refreshment Fructus Alpiniae Oxyphyllaes.
One pair of prescriptions of Chinese medicine of the present invention is: Rhizoma Acori Graminei 10g, Pheretima 3g, Herba Epimedii 10g, Semen Cuscutae 10g, Fructus Lycii 10g, Typhonium flagelliforme (Lodd.) Blume 15g, Radix Polygalae 10g, Radix Salviae Miltiorrhizae 15g.
Preparation technology of the present invention is: A, Radix Notoginseng are pulverized and are fine powder; B, Rhizoma Acori Graminei distill out volatile oil, use beta-cyclodextrin inclusion compound; C, Radix Salviae Miltiorrhizae and Radix Polygalae reclaim ethanol with ethanol extraction, concentrate alcohol extract; D, Herba Epimedii, Semen Cuscutae, Pheretima, Fructus Lycii and Rhizoma Acori Graminei medicinal residues merge, and carry with decocting, and the aqueous extract slagging-off concentrates.With C, D two concentrated solution mixings, drying, be ground into fine powder, merge mixing, granulation, filler capsule with A, B again, promptly get medicine ' Changlongdan ' of the present invention.
Herba Epimedii, Fructus Lycii, Semen Cuscutae have the effect of kidney tonifying, essence replenishing benefit marrow among the present invention; The effect of Radix Notoginseng, Pheretima, Radix Salviae Miltiorrhizae tool blood circulation promoting and blood stasis dispelling, tonneau meridians; Rhizoma Acori Graminei, Radix Polygalae, but mind tranquilizing and the heart calming, waking up the patient from unconsciousness by dissipating phlegm, refreshment Fructus Alpiniae Oxyphyllae.All medicines share, and can nurse one's health effectively and shield and sustain essence, marrow, god, and looking the heart, brain, kidney is one, treating both the principal and secondary aspects of a disease.The present invention has that stripping is rapid, bioavailability is better and stay-in-grade characteristics, is convenient to take for a long time.
The long-term toxicity test for animals result of medicine ' Changlongdan ': rat was taken medicine for 13 weeks continuously, and general behavior, appetite, drinking-water etc. all do not have obviously influence.Hematological examination is the result show, behind oral this medicine erythrocyte, leukocyte, hemoglobin, platelet, clotting time etc. do not had obviously influence.System's pathologic finding does not have the obvious damage effect to each internal organs.Left alone without help medicine is done above inspection, all no abnormal change after two weeks.
Clinical efficacy: produce effects 6 examples, effective 31 examples, invalid 5 examples, total effective rate 88. 1%.
Claims (2)
1, a kind of oral Chinese patent medicine medicine ' Changlongdan ', the prescription of one pair of medicine ' Changlongdan ' is: Rhizoma Acori Graminei 10g, Pheretima 3g, Herba Epimedii 10g, Semen Cuscutae 10g, Fructus Lycii 10g, Typhonium flagelliforme (Lodd.) Blume 15g, Radix Polygalae 10g, Radix Salviae Miltiorrhizae 15g.
2, the preparation technology of medicine ' Changlongdan ' is: A, Radix Notoginseng are pulverized and are fine powder; B, Rhizoma Acori Graminei distill out volatile oil, use beta-cyclodextrin inclusion compound; C, Radix Salviae Miltiorrhizae and Radix Polygalae reclaim ethanol with ethanol extraction, concentrate alcohol extract; D, Herba Epimedii, Semen Cuscutae, Pheretima, Fructus Lycii and Rhizoma Acori Graminei medicinal residues merge, and carry with decocting, and the aqueous extract slagging-off concentrates; With C, D two concentrated solution mixings, drying, be ground into fine powder, merge mixing, granulation, filler capsule with A, B again, promptly get medicine ' Changlongdan ' of the present invention.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 99115605 CN1293990A (en) | 1999-10-25 | 1999-10-25 | Medicine 'Changlongdan' |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 99115605 CN1293990A (en) | 1999-10-25 | 1999-10-25 | Medicine 'Changlongdan' |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1293990A true CN1293990A (en) | 2001-05-09 |
Family
ID=5278540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 99115605 Pending CN1293990A (en) | 1999-10-25 | 1999-10-25 | Medicine 'Changlongdan' |
Country Status (1)
Country | Link |
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CN (1) | CN1293990A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100462095C (en) * | 2003-09-04 | 2009-02-18 | 深圳万基药业有限公司 | Brain and intellectual health care medicine and its preparation |
CN104173637A (en) * | 2014-08-05 | 2014-12-03 | 湖南中医药大学 | Traditional Chinese medicine composition for treating gerontic vascular dementia and preparation method thereof |
CN107022406A (en) * | 2017-03-24 | 2017-08-08 | 合肥云都棉花有限公司 | A kind of tonifying kidneys and nourishing brain cottonseed oil |
-
1999
- 1999-10-25 CN CN 99115605 patent/CN1293990A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100462095C (en) * | 2003-09-04 | 2009-02-18 | 深圳万基药业有限公司 | Brain and intellectual health care medicine and its preparation |
CN104173637A (en) * | 2014-08-05 | 2014-12-03 | 湖南中医药大学 | Traditional Chinese medicine composition for treating gerontic vascular dementia and preparation method thereof |
CN104173637B (en) * | 2014-08-05 | 2018-02-27 | 湖南中医药大学 | A kind of Chinese medicine composition for treating senile vascular dementia and preparation method thereof |
CN107022406A (en) * | 2017-03-24 | 2017-08-08 | 合肥云都棉花有限公司 | A kind of tonifying kidneys and nourishing brain cottonseed oil |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Publication of application | ||
C06 | Publication | ||
PB01 | Publication | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |