CN1291511A - Natural medicine for resisting cancer transfer - Google Patents

Natural medicine for resisting cancer transfer Download PDF

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Publication number
CN1291511A
CN1291511A CN 99115194 CN99115194A CN1291511A CN 1291511 A CN1291511 A CN 1291511A CN 99115194 CN99115194 CN 99115194 CN 99115194 A CN99115194 A CN 99115194A CN 1291511 A CN1291511 A CN 1291511A
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CN
China
Prior art keywords
ganoderma
powder
natural medicine
centrifugal
resisting cancer
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Pending
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CN 99115194
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Chinese (zh)
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黄晓维
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Hongkong Academy Of Medical Sciences
SANYOUQIKANG INDUSTRY CO LTD SICHUAN
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Hongkong Academy Of Medical Sciences
SANYOUQIKANG INDUSTRY CO LTD SICHUAN
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Priority to CN 99115194 priority Critical patent/CN1291511A/en
Publication of CN1291511A publication Critical patent/CN1291511A/en
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Abstract

A natural medicine for preventing cancer transfer is prepared from ganoderma extract powder (5-45 Wt.%), ganoderma spore powder (55-90) and animal chondroitin (3-20), and serves to directly or indirectly kill cancer cells, cut off their nutrient source and prevent cancer cells from transferring. Its advantages are simple preparing process, high effect and convenient application.

Description

Natural medicine for resisting cancer transfer
The invention belongs to the anticancer drugs field, particularly have the medicine of anticancer transferance.
Treatment for cancer is considered to a big difficult point of medical domain, and many in the world countries have dropped into great amount of manpower and material resources for capturing this difficulty, have obtained many gratifying achievements at present.But, clinical although existing tens kinds of cancer therapy drugs are used for, there is not a kind of medicine of anti-transfer to be widely adopted.And in fact, can effectively control some cancer by the operation and the radiotherapy of routine, the reason that really causes cancer patient death is the transfer and the recurrence of cancer mostly.Therefore, in a sense, the difficult point of treatment cancer is actually the transfer of prevention and control cancer.Chinese patent CN 1205231A discloses a kind of Ganoderma preparation, the advantage that it has good antitumaous effect and has no side effect, but to the control action of cancerometastasis a little less than, the target spot of controlling the cancer effect is single, and the oven dry under heating of Ganoderma extractum powder wherein, thereby cause certain efficacy component destroyed.
The object of the present invention is to provide a kind of medicine that has good anticancer transfer effect concurrently, and preparation is simple, curative effect is obvious, taking convenience.
(shown below being weight percentage) that the objective of the invention is to realize by following technical solution:
The smart powder 5%-45% of Ganoderma, Ganoderma spore powder 55%-90% is added with the plain 3%-20% of animal cartilage especially.
In the such scheme, the best is: the smart powder 5%-10% of Ganoderma, Ganoderma spore powder 85%-90%, the plain 5%-10% of animal cartilage.
Wherein, the Ganoderma epispore-seed-powder is breaking cellular wall or breaking cellular wall epispore-seed-powder not, through the room temperature vacuum drying to moisture content<10%.
The preparation method of the smart powder of Ganoderma is: Ganoderma sporophore is pulverized, sieve, minus sieve powder adds the water that commercial weight 4-6 doubly measures, boiled 30-40 minute, centrifugal or filtration, filtering residue adds commercial weight 3-5 water doubly again, boiled 25-40 minute, centrifugal or filter, filtering residue adds doubly water boil 25-40 minute of commercial weight 2-4 again, and is centrifugal or filter; Merge three times filtrate, again in the evaporation and concentration down of seething with excitement, vacuum decompression drying; Also available cryogenic vacuum concentrates, and spray drying obtains powder product, moisture content<10%.
With Ganoderma spore powder with cellular wall broken or not Ganoderma spore powder with cellular wall broken be raw material, vacuum drying is made powdery, moisture content<10%.
Press the formula proportion preparation, sieve, sterilization, packing gets the finished product natural medicine for resisting cancer transfer.
Contain ganoderan and animal cartilage element in the cancer therapy drug of the present invention.Medical research proves that ganoderan not only has direct killing action to primary carcinoma cell and secondary carcinoma cell, and the cancerous cell that is shifting in the blood vessel is also had direct killing action.Ganoderan also can strengthen the human body immunity, increase the vigor of the natural killer cell of human body itself, stimulate human body to accelerate to produce interleukin II and tumor necrosis factor, and natural killer cell (NK), interleukin II (IL-2) and tumor necrosis factor (TNF) all have the stronger ability of killing to cancerous cell.Therefore, the existing cancer ability of directly going out of ganoderan has indirect antitumaous effect again.
The medical investigator finds that cancerous cell can secrete a kind of platelet stimulating factor, and the cancerous cell that is shifting in the blood vessel is assembled on every side platelet; and the formation bulk, protect cancerous cell not to be killed with this, simultaneously; caused the obstruction of blood vessel, ganoderan can prevent that then platelet is agglomerating.
The animal cartilage element then has the effect of good prevention and control cancerometastasis, its process is as follows: when cancerous cell forms new cancer by shifting, cancerous cell secretes angiogenic growth factor (TAF), forms new vessels, so that to tumor supply nutrient it is grown up.And contain the anti-invasion factor (AIF), endothelial cell growth inhibitive factor (EGIF) and cartilage-derived growth inhibitive factor (CDI) in the animal cartilage element, these three kinds of factors (AIF, EGIF and CDI) can suppress the activity of angiogenic growth factor, new vessels can't be formed, thereby cut off the nutrition supply line of cancerous cell, the cancerous cell that causes shifting can't be survived and grow up, thereby embodies the significant anti-curative effect that shifts.
In addition; adopt high-tech supersonic speed ultra micro air-flow technology for broken wall; the gas that reaches 3 Mach with flow velocity is implemented the moment bump towards band at low temperatures to the Ganoderma epispore-seed-powder; help protecting ganoderan not destroyed by high temperature; and sporoderm-broken rate height; ganoderan in the Ganoderma spore powder easily is absorbed by the body, thereby improves curative effect.
Therefore, cancer therapy drug of the present invention has had further development on existing cancer therapy drug basis, particularly at generation, the development of tumor, shift the obvious curative effects (see figure 2) that each stage has many target position.And, because the consumption of Ganoderma epispore-seed-powder is big, when the smart dried bean noodles of Ganoderma is dry in addition without heating, kept the active ingredient in the Ganoderma well, made cancer therapy drug of the present invention have better the directly effect (see figure 1) of kill cancer cell, had no side effect, and preparation is simple, taking convenience.And have the body resistance strengthening and constitution consolidating, improve body immunity, calm, analgesic activity.Both can be used for the treatment of all kinds of, each phase cancer separately, and also can cooperate operation, radiotherapy, chemotherapy to use, and effectively reduce cancer metastasis and recurrence, and improve life quality greatly and prolong survival period.
Embodiment one
The preparation method of the smart powder of Ganoderma is: the entity of Ganoderma is pulverized, sieved, minus sieve powder adds the water of 4.5 times of amounts, boils 30 minutes, centrifugal or filter, filtering residue adds the water of 4 times of commercial weight again, boils 30 minutes, centrifugal or filter, filtering residue adds the water boil 35 minutes of 3.5 times of commercial weight again, and is centrifugal or filter; Filtering residue adds the water boil 30 minutes of 3.5 times of commercial weight again, and is centrifugal or filter; Merge three times filtrate, again in the evaporation and concentration down of seething with excitement, vacuum decompression drying; Obtain the smart powder of Ganoderma, moisture content<10%.
With through the Ganoderma spore powder of supersonic speed ultra micro air-flow breaking cellular wall or not Ganoderma spore powder with cellular wall broken be raw material, vacuum drying is made powdery, moisture content<10%.
With 80 parts of Ganoderma spore powders, add 10 parts in the smart powder of Ganoderma, add plain 10 parts of animal cartilage, mix, sieve, sterilization, pack the product natural medicine for resisting cancer transfer.
Embodiment two
The preparation method of the smart powder of Ganoderma is: Ganoderma sporophore is pulverized, crossed 100 mesh sieves, minus sieve powder adds the water of 5 amounts, boils 40 minutes, centrifugal or filter, filtering residue adds the water of 3 times of commercial weight again, boils 40 minutes, centrifugal or filter, filtering residue adds the water boil 40 minutes of 3 times of commercial weight again, and is centrifugal or filter; Filtering residue adds the water boil 30 minutes of 3.5 times of commercial weight again, and is centrifugal or filter; Merge three times filtrate, in the evaporation and concentration down of seething with excitement, cryogenic vacuum concentrates again, and spray drying obtains the smart powder of Ganoderma, moisture content<10%.
With through the Ganoderma spore powder of supersonic speed ultra micro air-flow breaking cellular wall or not Ganoderma spore powder with cellular wall broken be raw material, vacuum drying is made powdery, moisture content<10%.
With 90 parts of Ganoderma spore powders, add 5 parts in the smart powder of Ganoderma, add plain 5 parts of animal cartilage, mix, cross 100 mesh sieves, sterilization, pack the product natural medicine for resisting cancer transfer.
Embodiment three
The preparation method of the smart powder of Ganoderma is: Ganoderma sporophore is pulverized, sieved, minus sieve powder adds the water of 4.5 times of amounts, boils 30 minutes, centrifugal or filter, filtering residue adds the water of 4.5 times of commercial weight again, boils 35 minutes, centrifugal or filter, filtering residue adds the water boil 35 minutes of 4 times of commercial weight again, and is centrifugal or filter; Filtering residue adds the water boil 30 minutes of 3.5 times of commercial weight again, and is centrifugal or filter; Merge three times filtrate, again in the evaporation and concentration down of seething with excitement, vacuum decompression drying; Obtain the smart powder of Ganoderma, moisture content<10%.
With through the Ganoderma spore powder of supersonic speed ultra micro air-flow breaking cellular wall or not Ganoderma spore powder with cellular wall broken be raw material, vacuum drying is made powdery, moisture content<10%.
With 58 parts of Ganoderma spore powders, add 27 parts in the smart powder of Ganoderma, add plain 15 parts of animal cartilage, mix, sieve, sterilization, pack the product natural medicine for resisting cancer transfer.
With the product of the foregoing description preparation, take through patient, all obtain good therapeutic effect, the antagonism cancerometastasis has obvious effect.
Fig. 1 is the present invention and each constituent content comparison diagram of prior art.X1 Ganoderma spore powder among Fig. 1, the smart powder Ganoderma extractum of X2 Ganoderma, Y is the animal cartilage element.
Fig. 2 is many target spots of the present invention design sketch.
Zero normal cell among Fig. 2
Figure 9911519400071
Cancerous cell
→ direct killing cancer cell
The indirect killing cancer cell of → enhance immunity
NK (human body itself) natural killer cell
The white thin breast of IL-2 is situated between plain-2
The TNF tumor necrosis factor
→ act on the new vessels endotheliocyte
X Ganoderma extract (spore powder or smart powder)
Y animal cartilage element
A primary carcinoma kitchen range
B newly shifts cancer
C blood vessel or lymphatic vessel (blood and lymph circulation system)
F cancerous cell invasion and attack intravasation (quinoline crust)
The signal of the agglomerating backlash removing blood stasis of the thin breast of E cancer pipe loop jump route

Claims (4)

1. natural medicine for resisting cancer transfer is made up of smart powder of Ganoderma and Ganoderma spore powder, it is characterized in that the smart powder 5%-45% (weight) of Ganoderma, and Ganoderma spore powder 55%-90% is added with the plain 3%-20% of animal cartilage especially.
2. natural medicine for resisting cancer transfer according to claim 1 is characterized in that preferable content is Ganoderma spore powder 5%-10%, the smart powder 85%-90% of Ganoderma, the plain 5%-10% of animal cartilage.
3. natural medicine for resisting cancer transfer according to claim 1 is characterized in that the Ganoderma epispore-seed-powder is breaking cellular wall or breaking cellular wall epispore-seed-powder not, through the room temperature vacuum drying to moisture content<10%.
4. natural medicine for resisting cancer transfer according to claim 1, the preparation method that it is characterized in that the smart powder of Ganoderma is: Ganoderma sporophore is pulverized, sieve, minus sieve powder adds the water that commercial weight 4-6 doubly measures, and boils 30-40 minute, centrifugal or filter, filtering residue adds commercial weight 3-5 water doubly again, boils 25-40 minute, centrifugal or filtration, filtering residue adds commercial weight 2-4 times water boil 25-40 minute again, centrifugal or filtration; Merge three times filtrate, again in the evaporation and concentration down of seething with excitement, to paste, vacuum decompression drying or cryogenic vacuum concentrate, and spray drying obtains powder product, moisture content<10%.
CN 99115194 1999-10-10 1999-10-10 Natural medicine for resisting cancer transfer Pending CN1291511A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100348209C (en) * 2004-07-08 2007-11-14 乌鲁木齐优康来科技开发有限公司 Natural lycopene compound oil preparation and capsule and its preparing method and use
US7618638B2 (en) 2001-09-27 2009-11-17 Nippon Menard Cosmetic Co., Ltd. Matrix metalloprotease inhibitor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7618638B2 (en) 2001-09-27 2009-11-17 Nippon Menard Cosmetic Co., Ltd. Matrix metalloprotease inhibitor
CN100348209C (en) * 2004-07-08 2007-11-14 乌鲁木齐优康来科技开发有限公司 Natural lycopene compound oil preparation and capsule and its preparing method and use

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