CN1282564A - Adaptive optical retina imaging system (1) - Google Patents
Adaptive optical retina imaging system (1) Download PDFInfo
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- CN1282564A CN1282564A CN 99115051 CN99115051A CN1282564A CN 1282564 A CN1282564 A CN 1282564A CN 99115051 CN99115051 CN 99115051 CN 99115051 A CN99115051 A CN 99115051A CN 1282564 A CN1282564 A CN 1282564A
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- adaptive optics
- liner plate
- imaging system
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Abstract
An adaptive optical retina imaging system features that in the said optical imaging system, the phase lining board for converting the low-contrast retina cell phase to visual light intensity distribution and the confocal filtering diaphragm for eliminating stray light are arranged in the optical path between human pupil and CCD camera. Its advantages is the improved contrast and S/N ratio.
Description
The present invention is a kind of adaptive optics retina imaging system, relates to adaptive optics wavefront correction technical field, belongs to the armarium manufacturing technology field that is used for human eye retina's imaging.
United States Patent (USP) 5,777,719 have introduced a kind of adaptive optics retina imaging system, measure human eye aberration with Hartmann wave front sensor, proofread and correct measured aberration with the deformation reflection mirror of Unit 37, bore φ 100.Move one then and switch reflecting mirror, light beam is switched to CCD camera in the imaging optical path, thereby obtain the high-resolution retina image-forming of human eye pupil diffraction.Entering the preceding light beam of wave-front corrector is the different light paths structure with the light beam that reflects from wave-front corrector.Though this cover system can obtain retina image-forming, because human eye retina's cell is very high to the transmitance of light, be a kind of position of the low contrast object that distributes mutually, this system only improves imaging to reduce aberration, can not effectively differentiate phase object; Secondly, system's veiling glare is many, and imaging can not get good signal-to-noise.
The objective of the invention is to avoid above-mentioned the deficiencies in the prior art and a kind of adaptive optics retina imaging system is provided, adopt phase-contrast technique and confocal filtering mode to improve the contrast of phase object picture and the signal to noise ratio of raising picture.
Purpose of the present invention can reach by following measure: adaptive optics retina imaging system, adopt Hartmann wave front sensor to measure human eye aberration, wave-front corrector is proofreaied and correct the gained aberration, is imaged onto CCD camera target surface in the light path by folded light beam, thereby obtains human eye retina's picture.Entering the preceding light beam of wave-front corrector is non-light path altogether with the light beam that reflects from wave-front corrector.In the imaging optical system, the human eye pupil between the wave-front corrector, wave-front corrector to the light path between the CCD camera, be equipped with retina cell with low contrast distribute mutually phase liner plate that converts visible light distribution to and the confocal wave-filtration optical hurdle of eliminating veiling glare.
Purpose of the present invention can also reach by following measure: can there be the phase liner plate position of human eye pupil or this pupil real image in the imaging optical system; The phase liner plate places the minute surface of wave-front corrector, and available coating technique or etching technique are at the surface coating of wave-front corrector or be etched into the phase liner plate, and the two is structure as a whole; The phase liner plate places between imaging coupling object lens and the camera; The phase liner plate places between beam splitter and the reflecting mirror; Field stop face or field stop real image face can have the confocal wave-filtration optical hurdle in the imaging optical system; The confocal wave-filtration optical field is organized the public focus place with back group lens before Beam matching is telescopical; The public focus place of group and back group lens was equipped with the confocal wave-filtration optical hurdle simultaneously before Beam matching was telescopical.
Accompanying drawing is a structure chart of the present invention
The present invention is further elaborated below in conjunction with accompanying drawing:
As shown in the figure, adaptive optics retina imaging system with phase liner plate and confocal wave-filtration optical hurdle adopts Hartmann's optics sensor measurement human eye aberration, deformation reflection mirror is proofreaied and correct the gained aberration, is imaged onto CCD camera target surface in the light path by folded light beam, thereby obtains human eye retina's picture.Entering the preceding light beam of wave-front corrector is non-light path altogether with the light beam that reflects from wave-front corrector.In the system, be equipped with the phase liner plate (10) that the retina cell with low contrast distributes mutually and converts visible light distribution to.Phase liner plate (10) places the minute surface of wave-front corrector (11), available coating technique becomes the phase liner plate at the surface coating of wave-front corrector (11), as one. confocal wave-filtration optical hurdle (9) simultaneously or place Beam matching telescope (8) and (12) preceding group and back to organize the public focus place of lens separately constitute confocal wave filter.Wave-front corrector (11) is deformation reflection mirror (an or liquid crystal wave-front corrector, or micromechanics deformation of thin membrane mirror, or double piezoelectric ceramic distorting lens).
In the native system, human eye pupil (6) optogram is imaged in the target surface of CCD camera (24), according to Ze Nike (Zernike) phase-contrast method, the phase liner plate places optical imaging system pupil plane or aperture diaphragm face, it makes the position of center preface (or zero level angular spectrum) with respect to each diffraction spectra (angular spectrum at different levels) 1/4 cycle of lag or lead, for example phase liner plate (10) can be placed on the aperture diaphragm face or the pupil real image face position of this imaging optical system in the native system, as: place the position of human eye pupil (6) near pupil, perhaps phase liner plate (10) can be close to wave-front corrector (11) and place and (also the phase liner plate can be made with plated film or etching technique in wave-front corrector (11) surface, (10) and (11) are united two into one), can also be placed on reflecting mirror (13) to arbitrary pupil real image face between the CCD camera (24).Like this, if the phase object of a low contrast
F (x)=e
I φ (x)F (x) distributes for thing, and φ (x) is the distribution mutually of object, when | φ | in the time of＜＜1, following formula is written as:
F (x) ≈ 1+i φ (x) is distributed as in image planes after above-mentioned phase contrast optical system:
G (x)=1 ± 2 φ (x) G (x) is the image planes light distribution, thereby sightless the distribution mutually of object become visible light distribution.
During system works, at first carry out the optics adaptively correcting, the light by beacon (1) sends behind beam-expanding system (2) expansion bundle, reflecting mirror (3) and the polarizer (4), becomes the line polarisation; Reflect into human eye pupil (6) by spectroscope (5) again; The only depolarization of human eye pupil (6) fundus reflex, see through spectroscope (5), become the line polarisation behind the analyzer (7) (polarization direction is vertical with the polarizer), this light beam transmitted beam coupling telescope (8) is (according to the confocal imaging principle, confocal wave-filtration optical hurdle (9) places the field stop face or the field stop real image face of imaging system, for example on the confocal wave-filtration optical hurdle (9) at the public focus place of two groups of lens of Beam matching telescope (8), only allow the fundus reflex light transmission, thereby eliminate veiling glare (when therefore adopting confocal wave-filtration optical hurdle (9), can be without the polarizer (4) and analyzer (7)), again through phase liner plate (10), the deformation reflection mirror of being close to it (11) reflection, by Beam matching telescope (12), to reflecting mirror (13), reflecting mirror (13) sees through beam splitter (14) with reflected light and reflects into Hartmann wave front sensor (15), Hartmann wave front sensor (15) is delivered to datatron (16) with the error signal that records, be processed into control signal, after control signal send high-voltage amplifier (17) to amplify, be applied on the deformation reflection mirror (11), thus the wavefront error in the correction light path; Error correction finishes, datatron is controlled to picture lighting source (18) work, and the light that imaging lighting source (18) sends is through lamp optical system (19), optical filter (20), reflecting mirror (21), the passage of walking along above-mentioned beacon beam, behind the reflecting mirror (3) and the polarizer (4), become the line polarisation; Reflect into human eye pupil (6) by spectroscope (5) again; The only depolarization of fundus reflex, behind spectroscope (5), analyzer (7) (polarization direction is vertical with the polarizer), become the line polarisation, this light beam transmitted beam coupling telescope (8), reflect through phase liner plate (10) and the deformation reflection mirror (11) be close to it again, by Beam matching telescope (12), reflect into imaging coupling object lens (23) through reflecting mirror (13), beam splitter (14) and reflecting mirror (22), image in CCD camera (24) target surface, thereby obtain human eye retina's picture.Owing to used phase liner plate (10) in the system,, be converted into and position proportional intensity distributions that distributes mutually so the retina cell position of low contrast distributes mutually; The adaptive optics corrective control has been proofreaied and correct the aberration of human eye and imaging system, so CCD camera (24) can obtain high-resolution, contrast retina cell picture preferably; Phase liner plate (10) can be placed on the position of human eye pupil (6) or this pupil real image; Phase liner plate (10) can place the minute surface of wave-front corrector, and available coating technique or etching technique are at the surface coating of wave-front corrector or be etched into the phase liner plate, and the two is structure as a whole; The phase liner plate can also place wave-front corrector (11) minute surface to be become the image planes (as the liner plate (10) mutually of dotted line between figure reflecting mirror ((13)) and the beam splitter (14)) of real image by Beam matching telescope (12); It all is the same also can being positioned over the effect that obtains between imaging coupling object lens and the camera; According to the confocal imaging principle, confocal wave-filtration optical hurdle (9) places the field stop face or the field stop real image face of imaging system, for example on the confocal wave-filtration optical hurdle (9) at the public focus place of two groups of lens of Beam matching telescope (8), only allow the fundus reflex light transmission, thereby elimination veiling glare, when therefore adopting confocal wave-filtration optical hurdle (9), can be without the polarizer (4) and analyzer (7).
The present invention compares prior art and has following advantage: 1, adopt the phase liner plate, and the retina of low contrast is thin Born of the same parents distribute mutually and change visible, proportional light distribution into, make retina cell's picture contrast of low contrast Degree improves, and has improved the quality of picture; 2, adopt confocal filtering mode to eliminate veiling glare, improved the letter of picture The ratio of making an uproar; 3, the present invention has avoided the imaging definition decline that the light path switching causes. In sum, the present invention carries Supplied a kind of energy to obtain the adaptive optical retina imaging system of limitting and having good contrast near diffractive plate System.
Claims (9)
1, adaptive optics retina imaging system, entering the preceding light beam of wave-front corrector is non-light path altogether with the light that reflects from wave-front corrector, adopt Hartmann wave front sensor to measure human eye aberration, wave-front corrector is proofreaied and correct the gained aberration, be imaged onto CCD camera target surface in the light path by folded light beam, thereby obtain human eye retina's picture, it is characterized in that: in the imaging optical system, human eye pupil (6) is between the wave-front corrector (11), wave-front corrector (11) is equipped with retina cell with low contrast distribute mutually phase liner plate (10) that converts visible light distribution to and the confocal wave-filtration optical hurdle (9) of eliminating veiling glare to the light path between the CCD camera (24).
2, adaptive optics retina imaging system as claimed in claim 1 is characterized in that can there be phase liner plate (10) position of human eye pupil (6) in the imaging optical system or this pupil real image.
3, adaptive optics retina imaging system as claimed in claim 1 or 2 is characterized in that phase liner plate (10) places the minute surface of wave-front corrector (11), and available coating technique becomes the phase liner plate at the surface coating of wave-front corrector (11), and the two is structure as a whole.
4, adaptive optics retina imaging system as claimed in claim 1 or 2 is characterized in that phase liner plate (10) places between imaging coupling object lens (23) and the camera (24).
5,, it is characterized in that phase liner plate (10) places between beam splitter (14) and the reflecting mirror (13) as claim 1 or described adaptive optics retina imaging system.
6, adaptive optics retina imaging system as claimed in claim 1 is characterized in that in the imaging optical system that field stop face or field stop real image face can have confocal wave-filtration optical hurdle (9).
7,, it is characterized in that confocal wave-filtration optical hurdle (9) is positioned at preceding group and the public focus place of back group lens of Beam matching telescope (8) as claim 1 or 2 or 6 described adaptive optics retina imaging systems.
8,, it is characterized in that confocal wave-filtration optical hurdle (9) is positioned at preceding group and the public focus place of back group lens of Beam matching telescope (12) as claim 1 or 2 or 6 described adaptive optics retina imaging systems.
9,, it is characterized in that the look in the distance public focus place of (12) and (8) preceding group and back group lens of Beam matching is equipped with confocal wave-filtration optical hurdle (9) simultaneously as claim 1 or 2 or 6 described adaptive optics retina imaging systems.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB991150511A CN1148150C (en) | 1999-07-30 | 1999-07-30 | Adaptive optical retina imaging system (1) |
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| CNB991150511A CN1148150C (en) | 1999-07-30 | 1999-07-30 | Adaptive optical retina imaging system (1) |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100341260C (en) * | 2003-11-12 | 2007-10-03 | 大连理工大学 | Laser receiving device for laser alignment system with zone plate |
| CN100405016C (en) * | 2003-09-28 | 2008-07-23 | 中国科学院光电技术研究所 | Hartmann wave front sensor of aberration of human eyes based on microprism array |
| CN100450428C (en) * | 2004-05-24 | 2009-01-14 | 中国科学院光电技术研究所 | Vision simulation system for human eyes high order optical aberration correction |
| CN100458370C (en) * | 2003-09-28 | 2009-02-04 | 中国科学院光电技术研究所 | Hartmann wave front sensor in optical detection bade on microprism array |
| CN101288013B (en) * | 2005-09-19 | 2010-12-08 | Cdm光学有限公司 | Task-based imaging system |
| CN102175261A (en) * | 2011-01-10 | 2011-09-07 | 深圳大学 | Visual measuring system based on self-adapting targets and calibrating method thereof |
| CN103284688A (en) * | 2013-06-12 | 2013-09-11 | 中国科学院光电技术研究所 | Structural dark field adaptive optics retina imager |
| CN103315705A (en) * | 2013-06-12 | 2013-09-25 | 中国科学院光电技术研究所 | Polarization dark field self-adaptation optical retina imager |
| CN104352214A (en) * | 2014-11-13 | 2015-02-18 | 中国科学院光电技术研究所 | Wavefront modulation dark field self-adapted optical retina imager |
| CN108037075A (en) * | 2017-11-30 | 2018-05-15 | 哈尔滨工业大学 | Confocal microscope pattern aberration correction method |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100562726C (en) * | 2006-01-16 | 2009-11-25 | 中国科学院光电技术研究所 | Visual field offset Hartmann wave front sensor based on scanning galvanometer |
| CN101953676B (en) * | 2010-08-22 | 2012-10-03 | 中山联合光电科技有限公司 | Retina imaging optical system with high resolution and coaxial illumination |
-
1999
- 1999-07-30 CN CNB991150511A patent/CN1148150C/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100405016C (en) * | 2003-09-28 | 2008-07-23 | 中国科学院光电技术研究所 | Hartmann wave front sensor of aberration of human eyes based on microprism array |
| CN100458370C (en) * | 2003-09-28 | 2009-02-04 | 中国科学院光电技术研究所 | Hartmann wave front sensor in optical detection bade on microprism array |
| CN100341260C (en) * | 2003-11-12 | 2007-10-03 | 大连理工大学 | Laser receiving device for laser alignment system with zone plate |
| CN100450428C (en) * | 2004-05-24 | 2009-01-14 | 中国科学院光电技术研究所 | Vision simulation system for human eyes high order optical aberration correction |
| CN101288013B (en) * | 2005-09-19 | 2010-12-08 | Cdm光学有限公司 | Task-based imaging system |
| CN102175261A (en) * | 2011-01-10 | 2011-09-07 | 深圳大学 | Visual measuring system based on self-adapting targets and calibrating method thereof |
| CN102175261B (en) * | 2011-01-10 | 2013-03-20 | 深圳大学 | Visual measuring system based on self-adapting targets and calibrating method thereof |
| CN103284688A (en) * | 2013-06-12 | 2013-09-11 | 中国科学院光电技术研究所 | Structural dark field adaptive optics retina imager |
| CN103315705A (en) * | 2013-06-12 | 2013-09-25 | 中国科学院光电技术研究所 | Polarization dark field self-adaptation optical retina imager |
| CN104352214A (en) * | 2014-11-13 | 2015-02-18 | 中国科学院光电技术研究所 | Wavefront modulation dark field self-adapted optical retina imager |
| CN104352214B (en) * | 2014-11-13 | 2016-03-30 | 中国科学院光电技术研究所 | A kind of wavefront modification details in a play not acted out on stage, but told through dialogues adaptive optical retina imaging instrument |
| CN108037075A (en) * | 2017-11-30 | 2018-05-15 | 哈尔滨工业大学 | Confocal microscope pattern aberration correction method |
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