CN1263768A - Chinese-medicinal oral nerve growth liquid - Google Patents

Chinese-medicinal oral nerve growth liquid Download PDF

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Publication number
CN1263768A
CN1263768A CN 99120671 CN99120671A CN1263768A CN 1263768 A CN1263768 A CN 1263768A CN 99120671 CN99120671 CN 99120671 CN 99120671 A CN99120671 A CN 99120671A CN 1263768 A CN1263768 A CN 1263768A
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radix
gross weight
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ganqizi
fructus jujubae
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CN 99120671
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CN1086299C (en
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顾晓松
孟凡迅
张沛云
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NANTONG MEDICAL COLLEGE
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NANTONG MEDICAL COLLEGE
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Abstract

An oral liquid for treating peripheral nerve injury and neuron retromorphosis is prepared from 6 Chinese-medicinal materials including astragalus root, pilose asiabell root, raw white atractylodes rhizome, fleece flower root, etc. through removing impurities, drying, pulverizing, screening mixing, immersing in water, digestion, filter, concentrating, alcohol extraction, mixing and concentrating. Its advantages is sure curative effect.

Description

Herb mixture nerve growth decoction oral liquid
What the present invention relates to is a kind of herb mixture nerve growth decoction oral liquid for the treatment of illness such as nerve injury, neuron degeneration.
Adopt illness such as Chinese herbal treatment nerve injury, though long history is arranged, but because of prescription composition complexity, kind come out one after another, efficacy determination differs, be difficult to scale development and apply, there is a kind of medicine for the treatment of illness such as nerve injury to claim nerve growth factor abroad, belongs to Western medicine, cost an arm and a leg, use inconvenience, curative effect is also unsatisfactory.
The objective of the invention is to the defective at above-mentioned existence, propose a kind of herb mixture-nerve growth decoction, it can effectively treat illness such as nerve injury, neuron degeneration.
Technical solution of the present invention: its proportioning components: the Radix Astragali accounts for the 20-30% of gross weight, 20-25%, the 15-20% that Rhizoma Atractylodis Macrocephalae accounts for gross weight, 9-12%, the 15-20% that GANQIZI accounts for gross weight, the 11-15% that Radix Angelicae Sinensis accounts for gross weight that Radix Polygoni Multiflori accounts for gross weight that Radix Codonopsis accounts for gross weight.
Its composition also can increase Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, and they respectively account for the Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, GANQIZI, 8-12%, the 5-10% of Radix Angelicae Sinensis gross weight, 5-10%.Increase Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati are to adapt to better people's taste.
The production craft step branch (1) of herb mixture nerve growth decoction oral liquid is if need promptly get above-mentioned each composition Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, GANQIZI, Radix Angelicae Sinensis, Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati with Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, put, reject impurity respectively in order, and dried, make its water content reach 5-6%; (2) each composition is weighed to scale; (3) pulverize with pulverizer, 60 orders sieve; (4) if need be with Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, the 3-5 water logging doubly that adds its gross weight after also only the Radix Astragali, Radix Codonopsis, Radix Polygoni Multiflori, GANQIZI, Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi being mixed was steeped 24 hours, carry out under the normal temperature condition, after steaming and decocting makes its boiling then, constant temperature 60 minutes, carry out the screen plate filter and remove residue again, concentrate, every milliliter reaches 0.6 gram left and right sides crude drug; (5) with the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Polygonati alcohol extraction; (6) (4) are mixed the back reconcentration with (5), every milliliter reaches 1 gram left and right sides crude drug; (7) packing.
Advantage of the present invention:
This mixture belongs to pure Chinese medicinal preparation, it be in tradition on the basis of proved recipe, utilization modern biology technology is carried out the effect experiment of cellular level to its component, filter out and be rich in the active ingredient that promotes nerve growth, be combined into a kind of novel oral mixture according to Chinese medical theory, take and the result of preliminary clinic trial shows through the SD of sciatic nerve injury rat, this mixture has tangible promotion injured nerve repairing growth, promote the effect of functional rehabilitation, measure through toxicity test, this mixture toxicity is humble, any side effect do not occur, the clinical scope of application: refreshing on every side damage, illness such as neuron degeneration.Its active ingredient is definite, curative effect is clear and definite, clinical quantitative criteria, can scale development and apply.
Embodiment 1
Get 4 kilograms of the Radixs Astragali, 3 kilograms of Radix Codonopsis, 2.5 kilograms of Rhizoma Atractylodis Macrocephalae, 1.9 kilograms of Radix Polygoni Multiflori, GANQIZI 2..5 kilogram, Radix Angelicae Sinensis 2..1 kilogram
Production craft step branch (1) is got above-mentioned each composition Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, GANQIZI, Radix Angelicae Sinensis, puts, rejects impurity respectively in order, and dried, makes its water content reach 5%; (2) each composition is weighed to scale; Get 3 kilograms of the Radixs Astragali, 2 kilograms of Radix Codonopsis, 1.5 kilograms of Rhizoma Atractylodis Macrocephalae, 0.9 kilogram of Radix Polygoni Multiflori, 1.5 kilograms of GANQIZI, 1.1 kilograms of Radix Angelicae Sinensis; (3) pulverize with pulverizer, 60 orders sieve; (4) only soaked 24 hours adding 30 kg of water after the Radix Astragali, Radix Codonopsis, Radix Polygoni Multiflori, the GANQIZI mixing, carry out under the normal temperature condition, after steaming and decocting made its boiling then, constant temperature 60 minutes carried out the screen plate filter and remove residue again, concentrated, and every milliliter reaches 0.6 gram crude drug; (5) with Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis alcohol extraction; (6) (4) are mixed the back reconcentration with (5), every milliliter reaches 1 gram crude drug; (7) packing.
Embodiment 2
Get 3 kilograms of the Radixs Astragali, 3.3 kilograms of Radix Codonopsis, 2.7 kilograms of Rhizoma Atractylodis Macrocephalae, 2 kilograms of Radix Polygoni Multiflori, 2.7 kilograms of GANQIZI, 2.3 kilograms of Radix Angelicae Sinensis.
Increase by 1.9 kilograms of Fructus Jujubaes, 2.0 kilograms of Radix Et Caulis Acanthopanacis Senticosis, Rhizoma Polygonati 2..0 kilogram,
Production craft step branch (1) is got above-mentioned each composition Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, GANQIZI, Radix Angelicae Sinensis, Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, puts, rejects impurity respectively in order, and dried, makes its water content reach 6%; (2) get 2 kilograms of the Radixs Astragali, 2.3 kilograms of Radix Codonopsis, 1.7 kilograms of Rhizoma Atractylodis Macrocephalae, 1 kilogram of Radix Polygoni Multiflori, 1.7 kilograms of GANQIZI, 1.3 kilograms of Radix Angelicae Sinensis.Increase by 0.9 kilogram of Fructus Jujubae, 1.0 kilograms of Radix Et Caulis Acanthopanacis Senticosis, 1.0 kilograms of Rhizoma Polygonatis, (3) each composition is pulverized with pulverizer, and 60 orders sieve; (3) water logging that adds 64.5 kilograms after the Radix Astragali, Radix Codonopsis, Radix Polygoni Multiflori, GANQIZI, Fructus Jujubae, the Radix Et Caulis Acanthopanacis Senticosi mixing was steeped 24 hours, carry out under the normal temperature condition, after steaming and decocting makes its boiling then, constant temperature 60 minutes, carry out the screen plate filter and remove residue again, concentrate, every milliliter reaches 0.6 gram left and right sides crude drug; (5) with Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Polygonati alcohol extraction; (6) (4) are mixed the back reconcentration with (5), every milliliter reaches 1 gram left and right sides crude drug; (7) packing

Claims (3)

1, herb mixture nerve growth decoction oral liquid, it is characterized in that its proportioning components: the Radix Astragali accounts for the 20-30% of gross weight, 20-25%, the 15-20% that Rhizoma Atractylodis Macrocephalae accounts for gross weight, 9-12%, the 15-20% that GANQIZI accounts for gross weight, the 11-15% that Radix Angelicae Sinensis accounts for gross weight that Radix Polygoni Multiflori accounts for gross weight that Radix Codonopsis accounts for gross weight.
2, herb mixture nerve growth decoction oral liquid according to claim 1, the institute's composition that it is characterized in that it also can increase Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, and they respectively account for the Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, GANQIZI, 8-12%, the 5-10% of Radix Angelicae Sinensis gross weight, 5-10%.
3, the production technology of herb mixture nerve growth decoction oral liquid, it is characterized in that its processing step branch (1) is if need promptly get above-mentioned each composition Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Radix Polygoni Multiflori, GANQIZI, Radix Angelicae Sinensis, Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati with Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, put, reject impurity respectively in order, and dried, make its water content reach 5-6%; (2) each composition is weighed to scale; (3) pulverize with pulverizer, 60 orders sieve; (4) if need be with Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, the 3-5 water logging doubly that adds its gross weight after also only the Radix Astragali, Radix Codonopsis, Radix Polygoni Multiflori, GANQIZI, Fructus Jujubae, Radix Et Caulis Acanthopanacis Senticosi being mixed was steeped 24 hours, carry out under the normal temperature condition, after steaming and decocting makes its boiling then, constant temperature 60 minutes, carry out the screen plate filter and remove residue again, concentrate, every milliliter reaches 0.6 gram left and right sides crude drug; (5) with Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Polygonati alcohol extraction; (6) (4) are mixed the back reconcentration with (5), every milliliter reaches 1 gram left and right sides crude drug; (7) packing.
CN99120671A 1999-12-29 1999-12-29 Chinese-medicinal oral nerve growth liquid Expired - Lifetime CN1086299C (en)

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CN1263768A true CN1263768A (en) 2000-08-23
CN1086299C CN1086299C (en) 2002-06-19

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596978A (en) * 2015-12-23 2016-05-25 薛学明 Drug for treating nerve injury and preparation method thereof
CN111759915A (en) * 2020-07-20 2020-10-13 南通大学 Nerve regeneration compound preparation and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1048408C (en) * 1994-06-14 2000-01-19 鲁守龙 Medicine for curing nervous system injury and angionosis
CN1156608A (en) * 1996-12-10 1997-08-13 艾津华 Chinese medicine for treating nerve system disease and producing process thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596978A (en) * 2015-12-23 2016-05-25 薛学明 Drug for treating nerve injury and preparation method thereof
CN111759915A (en) * 2020-07-20 2020-10-13 南通大学 Nerve regeneration compound preparation and preparation method and application thereof
WO2022016827A1 (en) * 2020-07-20 2022-01-27 南通大学 Compound preparation for neuranagenesis, and preparation method therefor and use thereof

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