CN1262116A - Chinese patent medicine for treating intractable and habitual constipation - Google Patents

Abstract

A Chinese patent medicine in the form of honeyed pill for treating intractable and habitual constipation is prepared from 15 Chinese-medicinal materials including astragalus root, Chinese angelica root, peach kernel, curcuma root, poeonol, etc. Its advantages are easy preparing it, and high curative effect.

Description

The Chinese patent medicine of treatment intractable and habitual constipation

The present invention relates to the compound Chinese patent medicine of the anti-constipation of a kind of broad-spectrum.

Constipation is a kind of clinical common, multiple disease.All it is dry and hard to cause feces because of feces was detained water content of a specified duration, interior by excessive absorption in enteric cavity, and normal stool disappears, and promptly forms constipation.Its main cause can be divided into colonic constipation and proctogenous constipation.The former is meant that food debris transports slowly in colon, the latter is that food debris arrives and to remain in a standstill behind the rectum for a long time, and causes difficult defecation.As seen clinical have the organic illness of intestinal to cause constipation, but majority is the functional constipation that belongs to dysfunction.The traditional Chinese medical science is thought the formation of constipation, is because various illness or other reasons cause the body fluid consume, and cause constipation with dry stool, difficult defecation.At " interior warp " assertive evidence is belonged to the spleen nephropathy.Pulse Classic is thought has certain relation with lung, because of the event of the lung and the large intestine being interior-exteriorly related." all source of disease marquis's opinions " emphasized the interior knot of heresy of cold and heat, and body fluid is dry and astringent uninteresting.Recipes for Saving Lives then is divided into constipation five kinds, i.e. constipation due to pathogenic wind, constipation due to disorder of QI, wet secret, constipation due to accumulation of pathogenic cold, functional constipation are thought the disease of taste, intestine and small intestine, bladder.Jin Dynasty well-known doctor Li Dongyuan thinks that multiple reason causes body fluid to lose due to the void.In the treatise on Febrile Diseases, there are " constipation caused by accumulation of heat ", " constipation of YIN type " to reach the title of " spleen-constipation ",, constipation are divided into constipation caused by accumulation of heat and constipation of YIN type more according to the book of all families of successive dynasties.So-called constipation caused by accumulation of heat, every the stagnation of QI is not all right owing to tie in the excess-heat, causes large intestine to lose fortune, forms constipation person, the general designation constipation caused by accumulation of heat, as gastrointestine dryness heat, consumption of body fluid by heat, intestinal loses and makes moist, so that constipation, the genus constipation caused by accumulation of heat.Constipation of YIN type every because the deficiency of vital energy, yang deficiency, cause colon movement unable, the deficiency of YIN, insufficiency of blood, intestinal lose it and make moist, thereby constipation person is taken place.Constipation and cardiovascular and cerebrovascular disease, digestive disease, anorectal are multiple chronic disease close relation such as disease and diabetes, and be huge to the potential impact and the harm of human body, must prevent and treat early.

At present, in the medicine of treatment constipation, Chinese and western drugs all has, and is of a great variety.We find that by a large amount of clinical observations these medicines all exist some untoward reaction or contraindication, and work has brought inconvenience to clinical treatment, as: the Chinese medicine sennae stimulates colon that angor can be arranged; Radix Et Rhizoma Rhei is for a long time with can producing drug resistance, and the easy damaged gastrointestinal function; The chemicals methylcellulose can bring out intestinal obstruction; Phenolphthalein can cause anaphylactic reaction, enteritis, dermatitis and bleeding tendency etc.Now this quasi drugs also exists discharge function strong excessively divided by outside the last untoward reaction on the market, causes that body fluid is unbalance, water, electrolyte disturbance, acid base imbalance, even influence the heart, kidney, liver function.And toxic and side effects is big, old age, anemia of pregnant woman, child's inconvenience use or the like problem.

Purpose of the present invention just provides a kind of Chinese patent medicine for the treatment of intractable and habitual constipation, and this Chinese patent medicine toxic and side effects is little, and relapse rate is low, and effective percentage is higher.

The present invention acts on motherland's traditional medical theory, reform and optimize the medicine composition, screening natural edible-plant medicine is by the theory of Chinese medical science prescription, make it have bowel relieving relieving constipation, blood circulation promoting and blood stasis dispelling, clearing away heat and moistening the bowels, pleasant row stagnates, the effect of QI invigorating warming YANG, regulating QI to relieve pain, blood enriching and dryness moistening, the kidney invigorating of taste sun.

A kind of Chinese patent medicine for the treatment of intractable and habitual constipation, it is the medicament of being made by the following weight proportion raw material:

Radix Astragali 11.4-14.1 part Radix Angelicae Sinensis 8.0-11.1 part Semen Persicae 8.0-11.1 part

Radix Curcumae 6.6-8.7 part Fructus Crataegi 6.6-8.7 part Cortex Moutan 6.6-8.7 part

Fructus Trichosanthis 6.6-8.7 part Radix Aucklandiae 6.6-8.7 part Semen Arecae 4.4-7.1 part

Fructus Aurantii 4.4-7.1 part Radix Scutellariae 3.9-4.4 part Radix Et Rhizoma Rhei 3.9-4.4 part

Rhizoma Coptidis 3.2-3.8 part Pericarpium Citri Reticulatae 3.2-3.8 part Fructus Citri Sarcodactylis 3.1-3.5 part

Best proportioning of the present invention is:

9.6 parts in 9.6 parts of Semen Persicaes of 12.7 parts of Radix Angelicae Sinensis of the Radix Astragali

7.6 parts of 7.6 parts of Cortex Moutans of 7.6 portions of Fructus Crataegis of Radix Curcumae

5.7 parts of 7.6 portions of Semen Arecaes of 7.6 parts of Radix Aucklandiae of Fructus Trichosanthis

4.1 parts of 4.1 parts of Radix Et Rhizoma Rhei of 5.1 parts of Radix Scutellariae of Fructus Aurantii

3.2 parts of 3.5 portions of Fructus Citri Sarcodactylis of 3.5 parts of Pericarpium Citri Reticulataes of Rhizoma Coptidis

Sweet, the tepor of the used Radix Astragali in the Chinese patent medicine of the present invention, spleen reinforcing, lung have QI invigorating and give birth to effect positive, that benefit is defended consolidating superficial resistance.Contain saccharide, choline, aminoacid etc., expansible little blood vessel can improve circulation and the nutriture organized, and the excitor nerve effect is arranged, and various bacteria is had antibacterial action; Radix Angelicae Sinensis has the effect of enriching blood and invigorating blood circulation and moisturizing laxation, can control the constipation of blood deficiency deficiency of body fluid, contains ethereal oil, water-soluble alkaloid, Vit B12, and stronger bacteriostasis is arranged; Effects such as Semen Persicae is controlled the dryness of the intestine constipation, contains significant quantities of fat oil, and intrinsic purging and intestine lubricating action, contained amygdalin have antiinflammatory, detoxifcation, analgesia, moisten.Radix Curcumae has the usefulness of promoting QI circulation for relieving depression, analgesia; Hawthorn digesting eliminate indigestion, blood circulation promoting and blood stasis dispelling have strong antibiotic effect to dysentery bacterium; Cortex Moutan clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, have analgesic, the central inhibitory action of analgesia; Radix Aucklandiae promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion; The Semen Arecae regulating qi-flowing for activating stagnancy is with controlling abdominal distention constipation; The Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication is strengthened leukocytic phagocytic activity, function of gallbladder promoting is arranged, expand little blood vessel, blood pressure lowering, refrigeration function; The Radix Scutellariae heat-clearing and toxic substances removing, and broad-spectrum antiseptic and antiabortive effect are arranged.Fructus Trichosanthis has the effect of loosening bowel to relieve constipation, can control the exsiccant constipation of intestinal juice, contains triterpenoid saponin, organic acid, resin, saccharide, fatty oil, pigment etc., proves through zoopery, and the effect that increases hat flow, blood fat reducing is arranged; Fructus Aurantii dispelling the stagnated QI removing food stagnancy, is controlled constipation, stomachache distension at therapeutic method to keep the adverse QI flowing downwards relieving constipation, and gastrointestinal smooth muscle is had certain excitation, and can make gastrointestinal motility shrink rhythmicity increases.The Radix Et Rhizoma Rhei purging heat to relax the bowels is with the constipation due to dry stool of controlling the gastrointestinal excess-heat, abdominal pain with tenderness etc.Radix Et Rhizoma Rhei mainly contains emodin, emodin can stimulate intestinal wall, improve the intestinal contraction, secretion is increased, be easy to discharge and cause the close thing of enteral, Radix Et Rhizoma Rhei has inhibitory action to staphylococcus, dysentery, Bacillus typhi, bacillus pyocyaneus and fungus, but the secretion of facilitating digestion liquid has the effect of cholagogic and lithagogue, facilitating digestion, and can reduce cholesterolemia; The Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen is with controlling stagnation of QI in spleen and stomach, distension and fullness in the abdomen, this product contains volatile oil, and Main Ingredients and Appearance is limonene, cypress rafter aldehyde, nobiletin, hesperidin, inositol, VitB1 etc., and digestive tract is had demulcent stimulation, be beneficial to the discharge of gastrointestinal pneumatosis, can promote gastric secretion, help digestion; Fructus Citri Sarcodactylis is used for stagnation of QI due to depression of the liver, incoordination between the liver and stomach, gastral cavilty distending pain, vomiting uncomfortable in chest.

The present invention is through clinical use, confirm to all kinds constipation all have definitely, significant curative effect, and multiple acute and chronic disease had the auxiliary treatment effect, to receive and search a large amount of case data and analyze, data are as follows:

	Invalid	Generally	Well	Significantly	Total effective rate
						Clinical symptom disappearance		3.3％	15.5％	81.3％	??96.8％
Relieving constipation is the molding soft stool		2.4％	9％	88.6％	??97.6％
						The defecation rule, day just once		3.9％	12.7％	83.4％	??96.1％

Embodiment: take by weighing raw material by following proportioning, 3.5 kilograms of Fructus Citri Sarcodactylis of 3.5 kilograms of Pericarpium Citri Reticulataes of 4.1 kilograms of Rhizoma Coptidis of 4.1 kilograms of Radix Et Rhizoma Rhei of 5.7 kilograms of Radix Scutellariaes of 5.7 kilograms of Fructus Aurantiis of 7.6 kilograms of Semen Arecaes of 7.6 kilograms of Radix Aucklandiae of 7.6 kilograms of Fructus Trichosanthis of 7.6 kilograms of Cortex Moutans of 7.6 kilograms of Fructus Crataegis of 9.6 kilograms of Radix Curcumaes of 9.6 kilograms of Semen Persicaes of 12.7 kilograms of Radix Angelicae Sinensis of the Radix Astragali carry out sterilization treatment respectively with above-mentioned each raw material earlier for 3.2 kilograms, pressure is between the 103-137 handkerchief, temperature is between 121-126 ℃, pressing time of heating is between 20-30 minute, room temperature cooling then, again with each raw material pulverizing to 150 order fineness, mix homogeneously, mix with 25 kilograms of Mel, make honeyed pill.

Claims (2)

1, a kind of Chinese patent medicine for the treatment of intractable and habitual constipation is characterized in that it is the medicament of being made by the following weight proportion raw material:

Radix Astragali 11.4-14.1 part Radix Angelicae Sinensis 8.0-11.1 part Semen Persicae 8.0-11.1 part

Radix Curcumae 6.6-8.7 part Fructus Crataegi 6.6-8.7 part Cortex Moutan 6.6-8.7 part

Fructus Trichosanthis 6.6-8.7 part Radix Aucklandiae 6.6-8.7 part Semen Arecae 4.4-7.1 part

Fructus Aurantii 4.4-7.1 part Radix Scutellariae 3.9-4.4 part Radix Et Rhizoma Rhei 3.9-4.4 part

Rhizoma Coptidis 3.2-3.8 part Pericarpium Citri Reticulatae 3.2-3.8 part Fructus Citri Sarcodactylis 3.1-3.5 part

2, according to the treatment intractable described in the claim 1 and the Chinese patent medicine of habitual constipation, wherein the optimum weight proportioning of each raw material is:

9.6 parts in 9.6 parts of Semen Persicaes of 12.7 parts of Radix Angelicae Sinensis of the Radix Astragali

7.6 parts of 7.6 parts of Cortex Moutans of 7.6 portions of Fructus Crataegis of Radix Curcumae

5.7 parts of 7.6 portions of Semen Arecaes of 7.6 parts of Radix Aucklandiae of Fructus Trichosanthis

4.1 parts of 4.1 parts of Radix Et Rhizoma Rhei of 5.7 parts of Radix Scutellariaes of Fructus Aurantii

3.2 parts of 3.5 portions of Fructus Citri Sarcodactylis of 3.5 parts of Pericarpium Citri Reticulataes of Rhizoma Coptidis