CN1261122C - Chinese medicinal preparation for treating gastritis and gastric ulcer - Google Patents

Chinese medicinal preparation for treating gastritis and gastric ulcer Download PDF

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Publication number
CN1261122C
CN1261122C CN 200410012919 CN200410012919A CN1261122C CN 1261122 C CN1261122 C CN 1261122C CN 200410012919 CN200410012919 CN 200410012919 CN 200410012919 A CN200410012919 A CN 200410012919A CN 1261122 C CN1261122 C CN 1261122C
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preparation
gastric ulcer
radix
chinese medicinal
gastric
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CN1562122A (en
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陈然
邹中华
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Abstract

The present invention relates to a Chinese medicinal preparation for treating gastritis due to epigastralgia, gastric ulcer, indigestion, etc. The Chinese medicinal preparation is prepared from Roxburgh rose root, Urtica dentata Hand.-Mazz., tangerine peel, agrimony, Radix Cynanchi Wilfordii and sargentgloryvine stem. The preparation which has reasonable compatibility can help patients relieve and eliminate stomachache, bellyache, etc., normalize the spleen, clear the heat, promote digestion, regulate qi and reduce the turbid. Indicated by the acute toxicity test which is carried out in the basic Tongji Medical College of Huazhong University of Science and Technology, the preparation is poisonless. Proved by the pharmacodynamics test, the preparation has the functions of preventing the gastric mucosa from being damaged, abirritating stomachache and promoting intestinal movement. In addition, the preparation has obvious therapeutic effects on treating gastritis and gastric ulcer according to the clinical observation in the traditional Chinese medical hospital of Tianmen city.

Description

A kind of Chinese medicine preparation for the treatment of gastritis, gastric ulcer
Technical field the present invention relates to the Chinese medicine preparation of diseases such as a kind of gastritis that is used for the treatment of gastric abscess and causes, gastric ulcer and dyspepsia thereof.
Background technology ancients are a lot of to the argumentation of gastric abscess, and a difficult speech general introduction needs from the major function of stomach and the characteristic understanding of starting with.Stomach receiving food and drink, digesting food, with reduce to expensively, general rule is not expensive, if the impression of stomach abdomen is cold, heat, wet, the strongly fragrant factor affecting of food, cause can not with fall, the taste ascending or descending movement of vital Qi is not normal, often brings out gastric abscess.The Chinese medicine of now existing treatment gastritis, gastric ulcer, and applied for patent, as " a kind of medicine for the treatment of gastritis, gastric ulcer " (number of patent application 02109144), it adopts Fructus Citri, Herba Taraxaci, the Pseudobulbus Bletillae (Rhizoma Bletillae), Os Sepiae, Radix Notoginseng, Concha Arcae, Fructus Hordei Germinatus, Borneolum Syntheticum infusion to form." medicine of treatment chronic gastritis, gastric ulcer " (patent No. 00132261) is formulated with Talcum, Fructus Amomi Rotundus, Herba Dendrobii, Rhizoma Acori Graminei, Radix Bupleuri, Cortex Magnoliae Officinalis, Radix Isatidis, Pericarpium Citri Reticulatae, Fructus Schisandrae Chinensis, Flos Inulae, Radix Glycyrrhizae, Rhizoma Coptidis, Fructus Cucumidis sativi, Haematitum, Os Draconis, Fructus Citri Sarcodactylis, Herba Pogostemonis, the Rhizoma Anemarrhenae, Fructus Crataegi, Chinese juniper beach wormwood, Radix Angelicae Sinensis, Rhizoma Zingiberis, Cortex cinnamomi japonici (Ramulus Cinnamomi), Rhizoma Pinelliae (processed) and Radix Ophiopogonis." a kind of medicine for the treatment of gastroenteritic ulcer and gastritis " (number of patent application 98110445), be with the Pseudobulbus Bletillae (Rhizoma Bletillae), Oletum Trogopterori, Lignum Dalbergiae Odoriferae, the Radix Astragali, DABAI, Herba Agrimoniae, the Radix Stemonae, Cortex Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cyperi, Radix Et Rhizoma Rhei, Fructus Amomi, the Radix Aucklandiae, Radix Glycyrrhizae, Rhizoma Zingiberis, to forge extra large Octopus ocellatus Gray, Concha Ostreae (calcined), Radix Codonopsis be raw material, it is formulated to press certain weight ratio.But the Chinese medicine preparation that a kind of gastritis that is used for the treatment of gastric abscess and causes, gastric ulcer are not also arranged.
Summary of the invention the objective of the invention is at above-mentioned present situation, aims to provide the treatment of diseases gastritis such as gastritis, gastric ulcer and dyspepsia thereof that are used for the treatment of gastric abscess and cause, the Chinese medicine preparation of gastric ulcer.
A kind of Chinese medicine preparation for the treatment of gastritis, gastric ulcer is formulated by following composition, and the proportioning of each composition is:
Rhizoma Fagopyri Dibotryis 250-450g Radix Semiaquilegiae 80-200g
Radix Rosae Normalis 50-150g Herba Girardinlae Diversifoliae 50-150g
Pericarpium Citri Reticulatae 60-150g Herba Agrimoniae 20-140g
Radix cynanchi wilfordii 20-140g Caulis Sargentodoxae 20-140g.
This preparation compatibility is reasonable, through this agent treatment, can make that patient's stomach abdomen logically falls, spleen fortune multiple normal, clearing heat and promoting digestion disappears, QI movement being in harmonious way, opening or cleaning the turbid descending, all diseases alleviation of having a stomachache is disappeared.This agent is nontoxic, and gastric mucosa injury is had protective effect, and stomachache is had analgesic activity, and intestinal motility is had facilitation.This agent treatment gastritis, gastric ulcer etc. have significant curative effect.
This preparation of the specific embodiment is formulated by Rhizoma Fagopyri Dibotryis, Radix Semiaquilegiae, Radix Rosae Normalis, Herba Girardinlae Diversifoliae, Pericarpium Citri Reticulatae, Herba Agrimoniae, Radix cynanchi wilfordii, Caulis Sargentodoxae.
Enumerate formulation Example of the present invention below:
1 2 3 4 5 6 7
Rhizoma Fagopyri Dibotryis 250g 270g 320g 350g 380g 420g 450g
Radix Semiaquilegiae 80g 85g 125g 145g 165g 185g 200g
Radix Rosae Normalis 50g 53g 72g 89g 98g 120g 150g
Herba Girardinlae Diversifoliae 50g 60g 75g 90g 100g 130g 150g
Pericarpium Citri Reticulatae 60g 67g 72g 80g 92g 130g 150g
Herba Agrimoniae 20g 25g 38g 49g 82g 120g 140g
Radix cynanchi wilfordii 20g 27g 42g 59g 92g 125g 140g
Caulis Sargentodoxae 20g 26g 45g 62g 98g 135g 140g
Rhizoma Fagopyri Dibotryis relieving dyspepsia in the prescription of this agent, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, two medicines are principal agent, can manage it, can disappear, can be dry, can and, can play the effect of appetizing, pleasant, food stagnation removing; Radix Rosae Normalis and in, help digestion, antidiarrheal, Radix cynanchi wilfordii is good for the stomach, Herba Girardinlae Diversifoliae analgesia is dried, and strengthens principal agent and taste and the analgesic effect; Herba Agrimoniae hemostasis, the dyspepsia that disappears, loose fullness in the epigastrium and abdomen, the therapeutic method to keep the adverse QI flowing downwards, associating Radix Semiaquilegiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Heat-clearing and toxic substances removing, activating collaterals and eliminating stagnation are played in Caulis Sargentodoxae heat-clearing and toxic substances removing, promoting blood circulation by removing wind, dehumidifying, all medicines altogether, the merit of the relieving distension of regulating the flow of vital energy, stomach function regulating dehumidifying.
This preparation compatibility rationally, shoot the arrow at the target, can regulate the flow of vital energy help digestion, heat-clearing and toxic substances removing, expelling wind and activating blood circulation, relieving spasm to stop pain, astringing to arrest bleeding, but again full, the swollen knot that looses of stomach function regulating network, spleen invigorating soil, relieving distension, remove turbid damp.Through this agent treatment, can make that patient's stomach abdomen logically falls, spleen fortune multiple normal, clearing heat and promoting digestion disappears, QI movement being in harmonious way, opening or cleaning the turbid descending, all diseases alleviation of having a stomachache is disappeared.Diseases such as gastritis, gastric ulcer and caused dyspepsia thereof, the upper abdomen that can be widely used in the treatment gastric abscess clinically and cause is glutted, nauseating, stomachache.
This agent has been done acute toxicity test with the powder of this medicine to rat through preclinical medicine institute of Tongji Medical College, Huazhong Science and Technology Univ., proves nontoxic.Made dehydrated alcohol induced mice gastric mucosa pharmacodynamics test, confirming has protective effect to the dehydrated alcohol gastric mucosa injury; Done the influence test of acetic acid induced mice chemical irritation pain, confirming has significant analgesia role to the caused stomachache of chemical irritation; Done influence test, confirmed that motion has certain promotion to intestinal propulsion the mice bowel movement.
Said preparation is a capsule preparations, and specification is the 0.4g/ grain, patient's one after each meal, every day three times, each 4.Hubei Province Tianmen City institute of traditional Chinese medicine has done observation of curative effect test with this capsule to 62 routine gastroduodenal ulcer patients year June in January, 1999-2002, duodenal bulbar ulcer 41 examples in 62 examples, and gastric ulcer 21 examples are cured 58 examples, cure rate 93.54%; To 38 routine chronic gastritis patient treatments, effective percentage 94.74%.
The observation of curative effect test has been done to 150 routine gastroscopy patients diagnosed year March in August, 2003-2004, wherein acute gastritis 15 examples, chronic gastritis 41 examples, gastric ulcer 48 examples, duodenal ulcer 42 examples, plyability ulcer 4 examples.After the patient takes this agent, identify that with gastroscope total effective rate is 96%, concrete report sees Table 1:
Table 1
Total number of persons Produce effects Effectively Invalid Total effective rate
150 120 24 6 96%
The symptom curative effect sees Table 2:
Table 2
The symptom curative effect Total routine number Produce effects Effectively Invalid Total effective rate
Gastric abscess 135 80 50 5 96.3%
The abdominal distention belch 120 92 25 3 97.5%
Acid regurgitation 115 76 36 3 97.4%
Nausea and vomiting 50 38 10 2 96%
Confirm that this agent is glutted, nauseating to gastralgia, upper abdomen, dyspepsia and the acute and chronic gastritis, the gastroduodenal ulcer that show have excellent curative.

Claims (1)

1, a kind of Chinese medicine preparation for the treatment of gastritis, gastric ulcer is characterized in that by following composition formulatedly, and the proportioning of each composition is:
Rhizoma Fagopyri Dibotryis 250-450g Radix Semiaquilegiae 80-200g
Radix Rosae Normalis 50-150g Herba Girardinlae Diversifoliae 50-150g
Pericarpium Citri Reticulatae 60-150g Herba Agrimoniae 20-140g
Radix cynanchi wilfordii 20-140g Caulis Sargentodoxae 20-140g.
CN 200410012919 2004-03-29 2004-03-29 Chinese medicinal preparation for treating gastritis and gastric ulcer Expired - Fee Related CN1261122C (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN 200410012919 CN1261122C (en) 2004-03-29 2004-03-29 Chinese medicinal preparation for treating gastritis and gastric ulcer

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CN1261122C true CN1261122C (en) 2006-06-28

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100420477C (en) * 2006-04-21 2008-09-24 代北仓 A medicine for treating gastric disease and preparation method thereof
CN101559106B (en) * 2008-04-16 2011-01-26 袁焱 Medicament for treating gastritis
CN104771623A (en) * 2015-03-31 2015-07-15 佘延英 Medicine for treating gastric ulcer
CN107736615A (en) * 2017-12-04 2018-02-27 爱可道生物科技有限公司 A kind of globe artichoke digestion powder and preparation method
CN114569690B (en) * 2022-03-23 2023-03-03 南充市中医医院 Traditional Chinese medicine composition for treating helicobacter pylori infectious gastritis

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