CN1259033C - Compound toothpaste for eliminating dental plaque and its preparation method - Google Patents
Compound toothpaste for eliminating dental plaque and its preparation method Download PDFInfo
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- CN1259033C CN1259033C CN 200410013379 CN200410013379A CN1259033C CN 1259033 C CN1259033 C CN 1259033C CN 200410013379 CN200410013379 CN 200410013379 CN 200410013379 A CN200410013379 A CN 200410013379A CN 1259033 C CN1259033 C CN 1259033C
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Abstract
The present invention relates to compound toothpaste for eliminating smoke yellow dental plaque and a preparation method thereof. The compound toothpaste for eliminating smoke yellow dental plaque of the present invention comprises 0.5 to 1.2 portions of zinc phytate, 0.2 to 0.6 portion of a turmeric extract, 0.1 to 0.3 portion of fluoride, 70 to 95 portions of conventional toothpaste base material, and 80 to 100 portions of water by weight proportions. The compound toothpaste for eliminating smoke yellow dental plaque can also add 0.3 to 0.5 portion of zinc citrate. The present invention has the advantages of simultaneously retaining the anticaries function of the fluoride, the functions of smoke yellow spots elimination and antiphlogosis of the turmeric extract and the function of the zinc phytate of eliminating dental calculus, and skillfully borrowing the function of suppressing pigment precipitation of the zinc phytate for reducing the coloration effect of curcumin to teeth or toothbrushes.
Description
Technical field
The present invention relates to a kind of compound toothpaste for eliminating dental plaque and preparation method thereof.
Background technology
Existing toothpaste as dentifrice can divide three major types, anticarious tooth paste, antiinflammatory toothpaste, desensitizing toothpaste, the main fluoride of first kind toothpaste, second class are Chinese style Chinese herbal toothpaste and cation surfactant, as Radix Zanthoxyli, hibitane etc., the 3rd class: traditional Western-style toothpaste contains amine salt more, also has to contain strontium salt.Typical international monopoly has: U.S. Pat P4826675 in 1989, Japan Patent JP61200905, U.S. Pat A4259316, Chinese patent application 91107332,90105692 etc.
Often smoking, having tea easily to cause piling up at dental surface forms black, xanchromatic schmutzband, and common toothpaste is brushed teeth and is difficult to brush away, and has influenced the attractive in appearance and healthy of tooth.The existing method for whitening that cleans the teeth, what effect was best is the chemical bleaching method, utilizes the chemical bleaching agent, with tartar hydrochloric acid, dissolvings such as hydrogenperoxide steam generator, but when removing tartar, corrode tooth unavoidably.
Whitening toothpaste commonly used with abrasives such as calcium carbonate, silicon dioxide, mainly relies on the mechanical friction of physics, and it is better to remove food detritus effect, but it is undesirable to remove cigarette macula lutea, tea speckle, tartar effect.Cigarette macula lutea, tea speckle, tartar and tooth is solidified togather and prolong in time, more and more firm, very difficult the removal.The anticaries action of fluoride toothpaste is generally acknowledged; But the toothpaste of not only removing cigarette macula lutea tartar but also preventing decayed tooth is arranged seldom.
Domestic there are some researches show that the extract of Rhizoma Curcumae Longae extract, Radix Curcumae class has effect preferably to the smoke abatement macula lutea, but the curcumin in the Rhizoma Curcumae Longae extract allows the user produce resentment easily with the yellow of dying of tooth and toothbrush in commercial aesthetic easily.Rhizoma Curcumae Longae extract also has good antiinflammation simultaneously, has literature research to show that Rhizoma Curcumae Longae extract can be applicable in the toothpaste abroad.But how to keep the effect of Rhizoma Curcumae Longae extract smoke abatement macula lutea, antiinflammatory, can effectively the coloration of curcumin to tooth and toothbrush be reduced again, become Rhizoma Curcumae Longae key in application in toothpaste.The inventor just takes the lead in having used phytic acid zinc in the patent application of CN93112612 multipurpose tooth paste, be used to eliminate dental calculus, phytic acid zinc is white powder, certain mechanical strength is arranged, after phytic acid zinc becomes flexible the dental calculus dissolving earlier, be convenient to toothbrush with dental calculus brush down, but that cigarette macula lutea, tea speckle, tartar and tooth are solidificated in is very firm, the removal effect of phytic acid zinc is ideal not enough.
Summary of the invention
The purpose of this invention is to provide a kind of compound recipe toothpaste and preparation method thereof.The phytic acid zinc of this compound recipe toothpaste and Rhizoma Curcumae Longae extract be composite obviously to reduce in the Rhizoma Curcumae Longae extract curcumin to the coloration of tooth and toothbrush.
Technical scheme of the present invention is:
A kind of compound toothpaste for eliminating dental plaque comprises phytic acid zinc 0.5-1.2 part by weight ratio, Rhizoma Curcumae Longae extract 0.2-0.6 part, fluoride 0.1-0.3 part, conventional toothpaste base material 70-95 part, water 80-100 part.
Compound toothpaste for eliminating dental plaque also is added with zinc citrate 0.3-0.5 part.
Compound toothpaste for eliminating dental plaque, conventional toothpaste base material contains wetting agent 15-25 part, adhesive 1-1.5 part, abrasive 45-55 part, washing foaming agent 1.5-3 part, flavouring agent 0.8-1.4 part, sweeting agent 0.2-0.3 part, buffer agent 0.3-0.6 part, antiseptic 0.05-0.3 part.
Compound toothpaste for eliminating dental plaque comprises 0.6 part on phytic acid zinc by weight ratio, 0.5 part of Rhizoma Curcumae Longae extract, and 0.24 part of sodium fluoride, 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Compound toothpaste for eliminating dental plaque, the washing foaming agent sodium lauryl sulfate replaces with dodecylbenzene sodium sulfonate.
The preparation method of compound toothpaste for eliminating dental plaque, the preparation method that Rhizoma Curcumae Longae extract adopts is: the Rhizoma Curcumae Longae raw medicinal material is ground into coarse powder, add 70-85% alcohol reflux secondary, 2 hours for the first time, 10 times of amount ethanol, 2 hours for the second time, 8 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.06-1.10, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.
Compound recipe toothpaste advantage of the present invention is: kept the smoke abatement macula lutea of function, Rhizoma Curcumae Longae extract of fluoride preventing decayed tooth and the function that antiinflammation, phytic acid zinc are eliminated dental calculus simultaneously, that uses cleverly again that phytic acid zinc suppresses pigementation is used for reducing the coloration of curcumin to tooth or toothbrush.Phytic acid zinc suppresses visible the 34th page of upper right hurdle of " development of phytic acid zinc and the application in daily-use chemical industry thereof " (Beijing daily use chemicals .1991 (2) .-33-35) of report of the effect of pigementation.
The specific embodiment
Embodiment 1
Compound toothpaste for eliminating dental plaque, 0.5 part of Rhizoma Curcumae Longae extract, 0.24 part in fluoride; 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 2
Compound toothpaste for eliminating dental plaque adds 0.6 part on phytic acid zinc, 0.5 part of Rhizoma Curcumae Longae extract, 0.24 part in fluoride; 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 3
Compound toothpaste for eliminating dental plaque adds 0.6 part on phytic acid zinc, 0.4 part of zinc citrate, 0.24 part in fluoride; 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 4
Ordinary toothpaste.0.6 part of Flos Lonicerae, Flos Chrysanthemi Indici extract, 0.24 part in fluoride; 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 5
Getting cigarette macula lutea, tea speckle that hospital pulls up adheres to serious yellowish-brown and exsomatizes that 30 pieces of teeth are parallel at random to be divided into three groups:
Cigarette macula lutea, tea speckle adhere to and are meant seriously that the tooth surface cigarette macula lutea that exsomatizes, tea speckle adhere to and reach more than 50%.
Dip in toothbrush all surfaces that embodiment 1 or 2 or 4 toothpaste that provide are scrubbed the stripped tooth of moistening is provided, each one minute, each firmly uniformity was consistent.Brushed the back and more than 30 times, guaranteed to rinse well, be placed in the sealing bag, sooner or later respectively come again continuous 30 days with flushing with clean water.
The table 1 cigarette macula lutea tea speckle of the tooth variation of disappearing of observe exsomatizing.
| Sample | 3 days | 5 days | 30 days |
| Embodiment 1 | 5 teeth have obviously and disappear | 10 teeth have obviously and disappear | 10 teeth have obviously and disappear, and 7 teeth wherein expose the white flank of tooth |
| Embodiment 2 | 4 teeth have obviously and disappear | 10 teeth have obviously and disappear | 10 teeth have obviously and disappear, and 7 teeth wherein expose the white flank of tooth |
| Embodiment 4 | 0 tooth has obviously and disappears | 0 tooth has obviously and disappears | 0 tooth has obviously and disappears, and 0 tooth wherein exposes the white flank of tooth |
Get cigarette macula lutea, tea speckle that hospital pulls up and adhere to exsomatize 30 pieces of teeth of not serious yellowish-brown, add hydrochloric acid and scrub, and add hydrogen peroxide and scrub until tooth surface whitely entirely, parallelly at random be divided into three groups:
Cigarette macula lutea, tea speckle adhere to and not seriously are meant that the tooth surface cigarette macula lutea that exsomatizes, tea speckle adhere to and reach below 50%.
Dip in toothbrush all surfaces that embodiment 1 or 2 or 3 toothpaste that provide are scrubbed the stripped tooth of moistening is provided, each one minute, each firmly uniformity was consistent.After having brushed, toothpaste is immersed in stripped tooth surface 24 hours respectively, 72 hours, 144 hours, the reuse toothbrush brushed away toothpaste, and flushing with clean water is removed residue, so that investigate the adhesion condition of curcumin on tooth.
Table 2 observe to exsomatize tooth surface color change.Be used for investigating the adhesion condition of curcumin on tooth.
| Sample | 24 hours | 72 hours | 144 hours |
| Embodiment 1 | 3 teeth are still whiter by pale yellow 7 teeth of leucismus | 10 teeth Huang that all shoals | 10 teeth all deepen Huang |
| Embodiment 2 | 0 tooth is still whiter by pale yellow 10 teeth of leucismus | 3 teeth yellow 7 teeth that shoal are still whiter | 4 teeth yellow 6 teeth that shoal are still whiter |
| Embodiment 3 | 0 tooth is still whiter by pale yellow 10 teeth of leucismus | 0 tooth is still whiter by pale yellow 10 teeth of leucismus | 2 teeth are still whiter by pale yellow 8 teeth of leucismus |
The present invention produces effect to removing cigarette macula lutea tea speckle by the top Rhizoma Curcumae Longae extract that experimental results show that.
Ordinary toothpaste does not have effect to removing cigarette macula lutea tea speckle.
Phytic acid zinc and Rhizoma Curcumae Longae extract do not had negative effect to removing cigarette macula lutea tea speckle.
Curcumin easily on tooth adventitious deposit painted.
It is painted that phytic acid zinc can suppress the adventitious deposit of curcumin on tooth.
It is painted that phytic acid zinc and zinc citrate can suppress the adventitious deposit of curcumin on tooth, better effects if.
Embodiment 6
The preparation method of compound toothpaste for eliminating dental plaque, the Rhizoma Curcumae Longae raw medicinal material is ground into coarse powder, add 80% alcohol reflux secondary, 2 hours for the first time, 10 times of amount ethanol, 2 hours for the second time, 8 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.08, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.All the other are with embodiment 2.
Embodiment 7
The preparation method of compound toothpaste for eliminating dental plaque, the Rhizoma Curcumae Longae raw medicinal material is ground into coarse powder, add 70% alcohol reflux secondary, 2 hours for the first time, 10 times of amount ethanol, 2 hours for the second time, 8 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.06, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.All the other are with embodiment 2.
Embodiment 8
The preparation method of compound toothpaste for eliminating dental plaque, the Rhizoma Curcumae Longae raw medicinal material is ground into coarse powder, add 85% alcohol reflux secondary, 2 hours for the first time, 10 times of amount ethanol, 2 hours for the second time, 8 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.10, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.All the other are with embodiment 2.
Embodiment 9
Compound toothpaste for eliminating dental plaque, 0.5 part on phytic acid zinc, 0.2 part of Rhizoma Curcumae Longae extract, 0.1 part in fluoride; 80 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 10
Compound toothpaste for eliminating dental plaque, 1.2 parts on phytic acid zinc, 0.3 part of zinc citrate, 0.6 part of Rhizoma Curcumae Longae extract, 0.3 part in fluoride; 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 11
Compound toothpaste for eliminating dental plaque, 0.9 part on phytic acid zinc, 0.5 part of zinc citrate, 0.3 part of Rhizoma Curcumae Longae extract, 0.2 part in fluoride; 90 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
Embodiment 12
Compound toothpaste for eliminating dental plaque, conventional toothpaste base material contains 25 parts of wetting agent, 1.5 parts of adhesive, 55 parts of abrasives, 3 parts of washing foaming agent, 1.4 parts of flavouring agents, 0.3 part of sweeting agent, 0.6 part of buffer agent, antiseptic-0.3 part.All the other are with embodiment 2.
Embodiment 13
Compound toothpaste for eliminating dental plaque, conventional toothpaste base material contains 20 parts of wetting agent, 1.4 parts of adhesive, 50 parts of abrasives, 2 parts of washing foaming agent, 0.9 part of flavouring agent, 0.25 part of sweeting agent, 0.34 part of buffer agent, 0.1 part of antiseptic.All the other are with embodiment 2.
Embodiment 14
Compound toothpaste for eliminating dental plaque, washing foaming agent are 3 parts of dodecylbenzene sodium sulfonate.All the other are with embodiment 1.
Embodiment 15
Compound toothpaste for eliminating dental plaque also is added with strontium chloride: 0.3～0.5 part.All the other are with embodiment 3.
Embodiment 16
Compound toothpaste for eliminating dental plaque, 45 parts of phosphoric acid hydrogen dihydrates; 2 parts of silicon dioxide; 10 parts of glycerol; 10 parts of sorbitol; 1 part of carboxymethyl cellulose; 3 parts of sodium laurylsulfates; All the other together
Embodiment 3.
Embodiment 17
Compound toothpaste for eliminating dental plaque, 0.2 part of stannous fluoride; 39 parts of calcium pyrophosphates; Glycerol 10,20 parts of sorbitol; All the other are with embodiment 2.
Embodiment 18
Compound toothpaste for eliminating dental plaque, 0.76 part of sodium monofluorophosphate; 42 parts of insoluble Polymeric sodium metaphosphate ies, 5 parts of dicalcium phosphate dihydrates; 1 part of aluminium hydroxide; Ai Er half tongue extractum 1; 0.4 part of titanium dioxide; 0.5 part of sodium benzoate; 3 parts of N-sodium lauroyl sarcosines; All the other are with embodiment 2.
Embodiment 19
Compound toothpaste for eliminating dental plaque, 5 parts of N-sodium lauroyl sarcosines; 0.5 part of sodium laurylsulfate; 0.9 part of alginate jelly; 2 parts of polyoxyethylene 20 sorbitan monolaurates; 24 parts of silicon dioxide; All the other are with embodiment 2.
Embodiment 20
Compound toothpaste for eliminating dental plaque, 0.5 part on the phytic acid zinc of weight proportion, 0.2 part of Rhizoma Curcumae Longae extract, 0.3 part in fluoride, 95 parts of conventional toothpaste base materials, 100 parts in water.
Embodiment 21
Compound toothpaste for eliminating dental plaque, 1.2 parts on the phytic acid zinc of weight proportion, 0.6 part of Rhizoma Curcumae Longae extract, 0.1 part in fluoride, 70 parts of conventional toothpaste base materials, 80 parts in water.
Embodiment 22
Compound toothpaste for eliminating dental plaque, 1.1 parts on the phytic acid zinc of weight proportion, 0.3 part of Rhizoma Curcumae Longae extract, 0.2 part in fluoride, 85 parts of conventional toothpaste base materials, 90 parts in water.
Claims (5)
1, a kind of compound toothpaste for eliminating dental plaque comprises phytic acid zinc 0.5-1.2 part by weight ratio, Rhizoma Curcumae Longae extract 0.2-0.6 part, fluoride 0.1-0.3 part, conventional toothpaste base material 70-95 part, water 80-100 part is characterized in that: also be added with zinc citrate 0.3-0.5 part.
2, compound toothpaste for eliminating dental plaque according to claim 1, it is characterized in that: conventional toothpaste base material contains wetting agent 15-25 part, adhesive 1-1.5 part, abrasive 45-55 part, washing foaming agent 1.5-3 part, flavouring agent 0.8-1.4 part, sweeting agent 0.2-0.3 part, buffer agent 0.3-0.6 part, antiseptic 0.05-0.3 part.
3, compound toothpaste for eliminating dental plaque according to claim 2, it is characterized in that: comprise 0.6 part on phytic acid zinc by weight ratio, 0.5 part of Rhizoma Curcumae Longae extract, 0.24 part of sodium fluoride, 100 parts in water, conventional toothpaste base material is: 10 parts of wetting agent glycerol, 5 parts of sorbic acid, 5 parts of malonic acid; 1 part of adhesive xanthan gum; 20 parts in abrasive calcium phosphate, 0 part of silica 1,20 parts of titanium dioxides; 3 parts of washing foaming agent sodium lauryl sulfates; The flavouring agent Oleum Menthae Rotundifoliae, respectively 0.2 part of Oleum menthae, Fructus Citri Limoniae oil, citrus oils; 0.3 part of sweeting agent saccharin sodium, 0.3 part of buffer agent tetrasodium pyrophosphate; 0.05 part of preservative sodium benzoate.
4, compound toothpaste for eliminating dental plaque according to claim 3 is characterized in that: the washing foaming agent sodium lauryl sulfate replaces with dodecylbenzene sodium sulfonate.
5, the preparation method of the described compound toothpaste for eliminating dental plaque of claim 1, it is characterized in that: the preparation method that Rhizoma Curcumae Longae extract adopts is: the Rhizoma Curcumae Longae raw medicinal material is ground into coarse powder, add 70-85% alcohol reflux secondary, 2 hours for the first time, 10 times of amount ethanol, 2 hours for the second time, 8 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.06-1.10, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 200410013379 CN1259033C (en) | 2004-06-24 | 2004-06-24 | Compound toothpaste for eliminating dental plaque and its preparation method |
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| CN 200410013379 CN1259033C (en) | 2004-06-24 | 2004-06-24 | Compound toothpaste for eliminating dental plaque and its preparation method |
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| CN1259033C true CN1259033C (en) | 2006-06-14 |
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| CN 200410013379 Expired - Fee Related CN1259033C (en) | 2004-06-24 | 2004-06-24 | Compound toothpaste for eliminating dental plaque and its preparation method |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0620220A2 (en) * | 2005-12-20 | 2011-11-01 | Procter & Gamble | oral care compositions comprising zinc and phytate |
| ES2280136B1 (en) * | 2006-02-17 | 2008-08-16 | Universitat De Les Illes Balears | FIXED AND ZINC FIXED DOSE ASSOCIATION. |
| FR2905596A1 (en) * | 2006-09-11 | 2008-03-14 | Innoderm Sarl | Cosmetic/pharmaceutical composition for topical use, comprises a combination of citric acid and phytic acid and/or their derivatives useful as a non-irritating preservative in the treatment of oily skin and acne |
| CN101040828B (en) * | 2007-04-28 | 2010-05-19 | 长春迈灵生物工程有限公司 | Tooth whitening agent and the method for preparing the same |
| US8580234B2 (en) | 2008-11-19 | 2013-11-12 | Kao Corporation | Method for removing solid product formed on surfaces of teeth |
| CN102218021B (en) * | 2010-04-15 | 2013-01-23 | 刘钦 | Toothpaste for removing halitosis and preventing canker sore |
| JP5097841B2 (en) | 2011-04-08 | 2012-12-12 | 花王株式会社 | Oral composition |
| CN102335108A (en) * | 2011-10-25 | 2012-02-01 | 华南理工大学 | Extract additive for Chinese herbal medicine toothpaste |
| CN112999109A (en) * | 2021-03-16 | 2021-06-22 | 江苏雪豹日化有限公司 | Modified biological lysozyme composition |
| CN113384487A (en) * | 2021-06-30 | 2021-09-14 | 广州名大实业有限公司 | Formula of toothpaste capable of efficiently removing smoke spots |
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