CN1251720C - 用于治疗冠心病心绞痛的药物组合物 - Google Patents
用于治疗冠心病心绞痛的药物组合物 Download PDFInfo
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- CN1251720C CN1251720C CN 200410018357 CN200410018357A CN1251720C CN 1251720 C CN1251720 C CN 1251720C CN 200410018357 CN200410018357 CN 200410018357 CN 200410018357 A CN200410018357 A CN 200410018357A CN 1251720 C CN1251720 C CN 1251720C
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Abstract
Description
组别 | 剂量g/kg | 动物数(只) | 给药前血压 | 给药后2hr血压(M±SD) | ||
血压 | 变化值 | 变化% | ||||
模型组阳性对照组实验组 | --5.945.942.971.49 | 1010101010 | 148.0±14.8143.1±9.2146.0±10.7147.0±11.6146.0±12.6 | 151.0±16.6133.1±10.6129.0±10.8144.0±13.4135.6±13.5 | 3.0±4.8-10.0±7.5-17.0±5.7-13.0±8.4-10.4±4.2 | 1.98±3.2-6.52±5.3*-11.7±3.7**-8.12±5.8*-6.67±2.9* |
组别 | 剂量g/kg | 动物数(只) | 给药前血压 | 给药后1周血压(M±SD) | ||
血压 | 变化值 | 变化% | ||||
模型组阳性对照组实验组 | --5.945.942.971.49 | 1010101010 | 148.0±14.8143.0±9.2146.0±10.7147.0±11.6146.0±12.6 | 154.0±16.5128.0±10.6123.0±10.6129.0±13.4131.0±16.6 | 6.0±5.2-15.0±10.6-23.0±5.7-18.0±8.4-15.0±25.2 | 4.1±3.5-10.3±6.7**-16.4±3.7***-12.6±5.8**-10.4±5.7** |
组别 | 剂量(g/kg) | 动物数(只) | 心肌坏死百分率(Mean±SD) |
阴性对照组 | -- | 10 | 125.25±7.6 |
阳性对照组 | 5.94 | 10 | 10.9±3.1* |
实验组 | 5.94 | 10 | 5.7±2.1*** |
2.97 | 10 | 8.2±5.0** | |
1.48 | 10 | 11.1±4.2* |
组别 | 剂量(g/kg) | 动物数(只) | 血清甘油三脂(M±SD) | 血清总胆固醇(M±SD) |
阴性对照组 | -- | 10 | 2.617±0.501 | 8.59±1.878 |
阳性对照组 | 5.94 | 10 | 1.887±0.461** | 7.57±1.120** |
实验组 | 5.94 | 10 | 1.701±0.529** | 6.24±1.239** |
2.97 | 10 | 1.774±0.453** | 6.40±0.305** | |
1.48 | 10 | 1.879±0.420** | 7.44±1.451 |
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 200410018357 CN1251720C (zh) | 2004-05-14 | 2004-05-14 | 用于治疗冠心病心绞痛的药物组合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN 200410018357 CN1251720C (zh) | 2004-05-14 | 2004-05-14 | 用于治疗冠心病心绞痛的药物组合物 |
Publications (2)
Publication Number | Publication Date |
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CN1579487A CN1579487A (zh) | 2005-02-16 |
CN1251720C true CN1251720C (zh) | 2006-04-19 |
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Application Number | Title | Priority Date | Filing Date |
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CN 200410018357 Expired - Fee Related CN1251720C (zh) | 2004-05-14 | 2004-05-14 | 用于治疗冠心病心绞痛的药物组合物 |
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CN (1) | CN1251720C (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102846745A (zh) * | 2012-10-17 | 2013-01-02 | 广州博济医药生物技术股份有限公司 | 一种治疗冠状动脉硬化性心脏病的中药组合物及其制备方法 |
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2004
- 2004-05-14 CN CN 200410018357 patent/CN1251720C/zh not_active Expired - Fee Related
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Publication number | Publication date |
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CN1579487A (zh) | 2005-02-16 |
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