CN1245626C - 产前诊断早产、胎儿感染和胎儿损伤的诊断剂及含有它们的诊断试剂盒 - Google Patents
产前诊断早产、胎儿感染和胎儿损伤的诊断剂及含有它们的诊断试剂盒 Download PDFInfo
- Publication number
- CN1245626C CN1245626C CNB018192696A CN01819269A CN1245626C CN 1245626 C CN1245626 C CN 1245626C CN B018192696 A CNB018192696 A CN B018192696A CN 01819269 A CN01819269 A CN 01819269A CN 1245626 C CN1245626 C CN 1245626C
- Authority
- CN
- China
- Prior art keywords
- fetal
- mmp
- amniotic fluid
- antibody
- matrix metalloproteinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2000-0069283A KR100425525B1 (ko) | 2000-11-21 | 2000-11-21 | 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트 |
| KR2000/69283 | 2000-11-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1476537A CN1476537A (zh) | 2004-02-18 |
| CN1245626C true CN1245626C (zh) | 2006-03-15 |
Family
ID=19700313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB018192696A Expired - Fee Related CN1245626C (zh) | 2000-11-21 | 2001-08-01 | 产前诊断早产、胎儿感染和胎儿损伤的诊断剂及含有它们的诊断试剂盒 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7232661B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1336103A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4011479B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100425525B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1245626C (cg-RX-API-DMAC7.html) |
| AU (1) | AU2001275820A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002042770A1 (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104498431A (zh) * | 2015-01-23 | 2015-04-08 | 温州市中心医院 | 一种载玻片原位培养羊水细胞及核型处理分析的方法 |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2231791C2 (ru) * | 2002-09-26 | 2004-06-27 | Ахмадеева Эльза Набиахметовна | Способ диагностики внутриутробной инфекции новорожденных |
| GB2435510A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | Enzyme detection product and methods |
| GB2435512A (en) * | 2006-02-23 | 2007-08-29 | Mologic Ltd | A binding assay and assay device |
| GB2435511A (en) | 2006-02-23 | 2007-08-29 | Mologic Ltd | Protease detection |
| GB2437311A (en) * | 2006-04-07 | 2007-10-24 | Mologic Ltd | A protease detection product |
| EP2083863B1 (en) * | 2006-10-03 | 2015-03-18 | Genzyme Corporation | Antibodies to tgf-beta for use in the treatment of infants at risk of developing bronchopulmonary dysplasia |
| WO2008137567A1 (en) * | 2007-05-01 | 2008-11-13 | Cedars-Sinai Medical Center | Caspase inhibitors in the treatment of infection-associated preterm delivery |
| CN110208540B (zh) * | 2008-10-31 | 2024-02-09 | 耶鲁大学 | 子痫前期检测和治疗的方法和组合物 |
| EP2510356B1 (en) * | 2009-12-08 | 2018-10-31 | Cedars-Sinai Medical Center | Diagnostic method to identify women at risk for preterm delivery |
| ES2614059T3 (es) | 2011-03-17 | 2017-05-29 | Cedars-Sinai Medical Center | Biomarcador de diagnóstico para predecir las mujeres en riesgo de parto prematuro |
| EP2997370A4 (en) * | 2013-05-16 | 2017-01-18 | Basetra Medical Technology Co. Ltd. | Fetal diagnostics using fetal cell capture from maternal blood |
| US20160130553A1 (en) | 2014-05-15 | 2016-05-12 | Kellbenx Incorporated | PREPARATION OF FETAL NUCLEATED RED BLOOD CELLS (NRBCs) FOR DIAGNOSTIC TESTING |
| US12202890B1 (en) | 2014-11-07 | 2025-01-21 | Kellbenx Incorporated | Antibodies for detection and enrichment of fetal cells and their use |
| KR101578526B1 (ko) * | 2015-07-14 | 2015-12-17 | 이화여자대학교 산학협력단 | 32주 미만의 조산 위험성을 예측하기 위한 마커 il-13 및 이의 이용 |
| KR101695347B1 (ko) | 2015-10-12 | 2017-01-11 | 이화여자대학교 산학협력단 | 유전자의 CpG 메틸화 변화를 이용한 조산 위험성 예측용 조성물 및 이의 이용 |
| KR101589673B1 (ko) * | 2015-10-12 | 2016-01-28 | (주)휴레이포지티브 | 시약 키트의 이미지를 통한 감염병 진단 방법 및 장치 |
| AU2016349390A1 (en) | 2015-11-06 | 2018-05-10 | Amnion Life, LLC | Premature infant amniotic bath incubator |
| US20200191801A1 (en) * | 2016-12-23 | 2020-06-18 | Susanne PANGRATZ-FÜHRER | Alpha-b crystallin in the diagnosis of neonatal brain damage |
| WO2018220129A1 (en) | 2017-05-31 | 2018-12-06 | B.R.A.H.M.S Gmbh | Mmp-8 as a marker for identifying infectious disease |
| EP3438668A1 (en) | 2017-08-04 | 2019-02-06 | B.R.A.H.M.S GmbH | Diagnosis and risk stratification of fungal infections |
| EP3682247B1 (en) | 2017-09-13 | 2022-02-09 | B.R.A.H.M.S GmbH | Proadrenomedullin as a marker for abnormal platelet levels |
| EP3502706A1 (en) | 2017-12-20 | 2019-06-26 | B.R.A.H.M.S GmbH | Workflow for risk assessment and patient management using procalcitonin and midregional-proadrenomedullin |
| RU2687486C1 (ru) * | 2018-02-05 | 2019-05-14 | Федеральное государственное бюджетное образовательное учреждение высшего образования Кубанский государственный медицинский университет Министерства Здравоохранения Российской Федерации (ФГБОУ ВО КУбГМУ МЗ РФ) | Способ определения степени риска внутриутробной инфекции плода у женщин, перенесших грипп A(H1N1) в период беременности |
| KR102184911B1 (ko) * | 2019-06-07 | 2020-12-01 | 한림대학교 산학협력단 | miR-548을 함유하는 조산 예방 또는 치료제 조성물 |
| CN111513729B (zh) * | 2020-05-07 | 2021-04-27 | 吉林大学 | 一种高效的产前诊断间期胎儿细胞检测装置 |
| KR102339013B1 (ko) * | 2020-11-16 | 2021-12-14 | 주식회사 옵티바이오 | 양수 검체 내 mmp-8 정량화가 가능한 체외 진단 키트 |
| KR20240083552A (ko) | 2022-12-05 | 2024-06-12 | 주식회사 제이스텍 | 진단키트용 비드의 공급 및 투입장치 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5597700A (en) * | 1994-04-28 | 1997-01-28 | California Research, Llc | Method for detecting free insulin-like growth-factor-binding protein 1 and a test device for detecting the ruptures of fetal membranes using the above method |
| FI98961C (fi) * | 1994-08-26 | 1997-09-10 | Medix Biochemica Ab Oy | Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi |
| US5545616A (en) * | 1994-09-22 | 1996-08-13 | Genentech, Inc. | Method for predicting and/or preventing preterm labor |
-
2000
- 2000-11-21 KR KR10-2000-0069283A patent/KR100425525B1/ko not_active Expired - Lifetime
-
2001
- 2001-08-01 WO PCT/KR2001/001306 patent/WO2002042770A1/en not_active Ceased
- 2001-08-01 US US10/415,763 patent/US7232661B2/en not_active Expired - Fee Related
- 2001-08-01 CN CNB018192696A patent/CN1245626C/zh not_active Expired - Fee Related
- 2001-08-01 EP EP01953363A patent/EP1336103A4/en not_active Withdrawn
- 2001-08-01 JP JP2002544659A patent/JP4011479B2/ja not_active Expired - Fee Related
- 2001-08-01 AU AU2001275820A patent/AU2001275820A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104498431A (zh) * | 2015-01-23 | 2015-04-08 | 温州市中心医院 | 一种载玻片原位培养羊水细胞及核型处理分析的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20040029176A1 (en) | 2004-02-12 |
| CN1476537A (zh) | 2004-02-18 |
| WO2002042770A1 (en) | 2002-05-30 |
| AU2001275820A1 (en) | 2002-06-03 |
| JP4011479B2 (ja) | 2007-11-21 |
| KR100425525B1 (ko) | 2004-03-30 |
| KR20020039458A (ko) | 2002-05-27 |
| US7232661B2 (en) | 2007-06-19 |
| EP1336103A4 (en) | 2007-05-09 |
| JP2004522942A (ja) | 2004-07-29 |
| EP1336103A1 (en) | 2003-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SEOUL NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOP Free format text: FORMER OWNER: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION Effective date: 20131217 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20131217 Address after: Seoul, South Korea Patentee after: Seoul Nat Univ Ind Foundation Address before: Seoul, South Kerean Patentee before: Obstetrics Unit Efforts Consortium of Soer Univ. |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060315 Termination date: 20190801 |
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| CF01 | Termination of patent right due to non-payment of annual fee |