CN1238706C - Cross flow guiding type minisize static agitator - Google Patents
Cross flow guiding type minisize static agitator Download PDFInfo
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- CN1238706C CN1238706C CN 200310108539 CN200310108539A CN1238706C CN 1238706 C CN1238706 C CN 1238706C CN 200310108539 CN200310108539 CN 200310108539 CN 200310108539 A CN200310108539 A CN 200310108539A CN 1238706 C CN1238706 C CN 1238706C
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- guide blocks
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- 230000003068 static effect Effects 0.000 title claims abstract description 13
- 239000012530 fluid Substances 0.000 claims abstract description 20
- 239000011159 matrix material Substances 0.000 claims description 23
- 239000011521 glass Substances 0.000 claims description 4
- 229910021419 crystalline silicon Inorganic materials 0.000 claims description 2
- 229920002379 silicone rubber Polymers 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 8
- 238000002156 mixing Methods 0.000 abstract description 8
- 238000009792 diffusion process Methods 0.000 abstract description 7
- 238000012545 processing Methods 0.000 abstract description 7
- 239000000126 substance Substances 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 5
- 239000000758 substrate Substances 0.000 abstract description 5
- 230000010354 integration Effects 0.000 abstract description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
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Abstract
The present invention discloses a crossed flow guide type miniature static agitator. Two input pipelines are etched at one end of the first block of substrates, the input pipelines are respectively connected with a first input opening and a second input opening, and an upper mixed cavity is connected to the crossed point of the input pipelines. Flow guide blocks periodically arranged in a crossed mode are arranged on both sides in the upper mixed cavity, and the slots of the flow guide blocks are mutually communicated. The other end of the upper mixed cavity is connected with an output opening. A lower mixed cavity is etched on the second block of substrates, flow guide blocks having the same sizes with those of the flow guide blocks in the first block of substrates are arranged on both sides in the lower mixed cavity, the flow guide blocks are periodically arranged in a crossed mode, and the slots of the flow guide blocks are communicated. The etched surfaces of the two blocks of substrates are mutually bonded, and an enclosed three-dimensional pipeline is formed. Shear flow and extension flow are generated in a flow field by utilizing the flow guide blocks periodically arranged, interface areas between different fluid bodies are increased, and meanwhile, the effect of molecular diffusion is enhanced, so the purpose of quick and high-efficient mixing is achieved. The present invention has the characteristics of simple structure, easy integration, simple processing technique, etc. The present invention is particularly suitable for micro chemical analysis systems.
Description
Technical field
The present invention belongs to microfluid chemical analysis system device, the miniature static mixer of particularly a kind of intersection flow-guiding type.
Background technology
Microfluid system can be defined as handling microlitre so that receive the MEMS system of upgrading fluid.The microfluid chemical analysis system has following advantage: short response time, less reagent and sample consumption, be easy to characteristics such as miniaturization and robotization, efficient height.The function of little chemical analysis system comprises sampling, pre-service, mixing, chemical reaction, separation, aftertreatment and identification etc.The purpose of hybrid processing is to be used for reducing heterogeneity, for example is used for dilution, perhaps is used for strengthening chemical reaction rate, and it is very important therefore realizing mixing fast and efficiently.
According to application of mixture theory, the main cause of produce mixing is the redistribution of relative position between the different fluid that forms of the convection action owing to the flow field, thus the process that causes various fluids to mix mutually; At molecular scale, because the Brownian movement of molecule produces diffusion, the drive fluid molecule, impels fluid to reach molecular level and evenly mixes to the diffusion of concentration lower from the concentration eminence simultaneously.
For microfluid system, because existing micro-processing technology is used in the restriction of yardstick, be difficult to adopt rotation stirring structure with movable member, equally also be difficult to process the complex three-dimensional structure that is similar to conventional static mixer form.And for microfluid system, its flow belongs to microlitre even receives upgrading, and volume is little, and speed is low, and it is moving to belong to low Reynolds number flow, if no strong external disturbance, fluid maintenance laminar condition.Therefore under the microscale condition, for reaching the mixed uniformly purpose of molecular level, the design of micro-mixer should be strengthened the molecular diffusion effect.Therefore domestic and international at present quiet, the dynamic micro mixer of studying, mainly be to utilize the principle that strengthens the molecular diffusion effect, increase the contact area between the different liquids by the structural design of runner, disturbance machinery or other modes, reduce the volume of fluid element, reach the purpose that realizes mixing.
Desirable micro-mixer should have following characteristics: fast, flow is adjustable, volume is little, concentration is adjustable, it is integrated to be easy to.Existing micro-mixer, because the restriction of processing technology, majority is a planar structure, the micro-mixer that for example utilizes a plurality of intersection microchannels to form, such micro-mixer takes up room greatly, and efficient is lower; Complicated processing technology is adopted in also having of other, for example by piezoelectric crystalline film, applies alternating electric field generation ultrasonic vibration simultaneously and mixes; Or adopt and to apply electric field and magnetic field simultaneously, by Lorentz force electrolytical effect being reached the purpose of mixing, such structure not only takes up room greatly, and processed complex, is difficult to integratedly, and cost is also higher.Static mixer is not owing to need moving component, mixing neither be finished by external stirring, but the proper motion that produces when utilizing flow of liquid to cross mixed cell, so development structure miniature static mixer simple, that be easy to process is significant for the practicalization of little chemical analysis system.
Summary of the invention
In order to overcome above-mentioned the deficiencies in the prior art and defective, the object of the present invention is to provide the miniature static mixer of a kind of fast and efficiently intersection flow-guiding type that is applicable to little chemical analysis system.
In order to achieve the above object, the technical solution used in the present invention is that it comprises: first matrix, second matrix, wherein be etched with first, second input port on first matrix surface, first, second input channel that one end is connected with first, second input port, and the top hybrid chamber that is communicated with first, second input channel infall, both sides have the baffle that is the cycle cross arrangement successively, two baffles were arranged in each cycle, lay respectively at the and arranged on left and right sides of top hybrid chamber, another termination delivery outlet of top hybrid chamber; Be etched with the bottom hybrid chamber on the surface of second matrix, there is the baffle with first matrix same size, aligned identical mode hybrid chamber interior both sides in bottom, and two baffles were arranged in each cycle, lay respectively at the and arranged on left and right sides of bottom hybrid chamber; The mutual bonding of etched surface of first matrix, second matrix, and make the side wall surface aligning of upper and lower part hybrid chamber obtain a whole hybrid chamber, in each cycle four baffles are arranged in the whole hybrid chamber, two baffles that wherein are positioned at the top hybrid chamber and two baffles that are positioned at the bottom hybrid chamber lay respectively at the both sides of whole hybrid chamber, fluid in top hybrid chamber and the bottom hybrid chamber is communicated with, forms the three-dimensional tube that seals.
In top hybrid chamber and bottom hybrid chamber, the angle α of each piece baffle and side wall surface is 30 °～60 °, and the projected length m of baffle on the hybrid chamber cross-sectional direction is 0.5～0.8 with the ratio of hybrid chamber width n.
Said matrix material is organic glass or crystalline silicon or glass or pottery or silicon rubber.
The present invention compares with background technology, the useful effect that has is: by the baffle of alternately arranging is set in pipeline, can produces shear flow and extend stream in the flow field, increase the interfacial area between different fluid, strengthen the molecular diffusion effect, finally realize the even mixing of molecular level.Miniature static mixer provided by the invention is made up of a plurality of mixed cells, can select the mixed cell of different numbers according to practical application.Characteristics such as the present invention has simple in structure, and easy of integration, processing technology is simple are specially adapted to little chemical analysis system.
Description of drawings
The invention will be further described below in conjunction with drawings and Examples.
Fig. 1 is a structural principle synoptic diagram of the present invention;
Fig. 2 is last basal body structure synoptic diagram, and etched surface upwards;
Fig. 3 is the lower substrate structural representation, and etched surface upwards;
Fig. 4 is the D partial enlarged drawing of Fig. 1;
Fig. 5 is the sectional view of Fig. 1 C-C.
Embodiment
As Fig. 1, Fig. 2, shown in Figure 3, it comprises: first matrix A, second matrix B, wherein be etched with first, second input port 1 on first matrix A surface, first, second input channel 2 that one end is connected with first, second input port 1, and the top hybrid chamber 6 that is communicated with first, second input channel infall, both sides have the baffle that is the cycle cross arrangement successively, two baffles 4,5 were arranged in each cycle, lay respectively at the and arranged on left and right sides of top hybrid chamber, another termination delivery outlet 3 of top hybrid chamber 6; Be etched with bottom hybrid chamber 7 on the surface of second matrix B, there is the baffle with first matrix A same size, aligned identical mode hybrid chamber 7 interior both sides in bottom, two baffles 4 ', 5 ' were arranged in each cycle, lay respectively at the and arranged on left and right sides of bottom hybrid chamber 7; The mutual bonding of etched surface of first matrix A, second matrix B, and make the side wall surface aligning of upper and lower part hybrid chamber obtain a whole hybrid chamber, in each cycle four baffles 4,5,4 ', 5 ' are arranged in the whole hybrid chamber, two baffles 4 ', 5 ' that wherein are positioned at two baffles 4,5 of top hybrid chamber 6 and are positioned at bottom hybrid chamber 7 lay respectively at the both sides of whole hybrid chamber, fluid in top hybrid chamber 6 and the bottom hybrid chamber 7 is communicated with, forms the three-dimensional tube that seals.
As Fig. 4, shown in Figure 5, in top hybrid chamber 6 and bottom hybrid chamber 7, the angle α of each piece baffle and side wall surface is 30 °～60 °, and the projected length m of baffle on the hybrid chamber cross-sectional direction is 0.5～0.8 with the ratio of hybrid chamber width n.
After fluid entered hybrid chamber, because the effect of baffle up and down, top fluid will be walked around the baffle 4,5 on upper strata, lower floor's fluid also will be walked around the baffle 4 ', 5 ' of lower floor, so the flow direction of top fluid is different with the flow direction of lower floor's fluid, form and intersect, produce shear flow; Simultaneously because the cyclical variation of flow area in the hybrid chamber can produce extension stream; Reach volume that reduces fluid element and the purpose that increases the interfacial area between different fluid thus, strengthen the molecular diffusion effect, finally reaching efficiently and fast, molecular level mixes.Baffle and center line are angled, and the deflection flow direction, so baffle can not cause that excessive pressure falls; In fluid entered hybrid chamber, baffle played guiding with regard to convection cell.
Miniature static mixer provided by the invention, adopting based on plane etching processing technology is the three-dimensional structure process technology on basis.
Claims (3)
1, the miniature static mixer of a kind of intersection flow-guiding type, it is characterized in that it comprises: first matrix (A), second matrix (B), wherein be etched with first on the surface of first matrix (A), second input port (1), one end and first, second input port (1) be connected first, second input channel (2), and with first, the top hybrid chamber (6) that the second input channel infall is communicated with, both sides have the baffle that is the cycle cross arrangement successively, two baffles (4 were arranged in each cycle, 5), lay respectively at the left side of top hybrid chamber, right both sides, another termination delivery outlet (3) of top hybrid chamber (6); Be etched with bottom hybrid chamber (7) on the surface of second matrix (B), there is the baffle with first matrix (A) same size, aligned identical mode the interior both sides of bottom hybrid chamber (7), two baffles (4 ', 5 ') were arranged in each cycle, lay respectively at the and arranged on left and right sides of bottom hybrid chamber (7); The mutual bonding of etched surface of first matrix (A), second matrix (B), and make the side wall surface aligning of upper and lower part hybrid chamber obtain a whole hybrid chamber, in each cycle four baffles (4,5,4 ', 5 ') are arranged in the whole hybrid chamber, two baffles (4,5) that wherein are positioned at top hybrid chamber (6) and two baffles (4 ', 5 ') that are positioned at bottom hybrid chamber (7) lay respectively at the both sides of whole hybrid chamber, fluid in top hybrid chamber (6) and the bottom hybrid chamber (7) is communicated with, forms the three-dimensional tube that seals.
2, the miniature static mixer of a kind of intersection flow-guiding type according to claim 1, it is characterized in that: in top hybrid chamber (6) and bottom hybrid chamber (7), the angle α of each piece baffle and side wall surface is 30 °～60 °, and the projected length m of baffle on the hybrid chamber cross-sectional direction is 0.5～0.8 with the ratio of hybrid chamber width n.
3, the miniature static mixer of a kind of intersection flow-guiding type according to claim 1 is characterized in that: said matrix material is organic glass or crystalline silicon or glass or pottery or silicon rubber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310108539 CN1238706C (en) | 2003-11-06 | 2003-11-06 | Cross flow guiding type minisize static agitator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310108539 CN1238706C (en) | 2003-11-06 | 2003-11-06 | Cross flow guiding type minisize static agitator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1542429A CN1542429A (en) | 2004-11-03 |
| CN1238706C true CN1238706C (en) | 2006-01-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200310108539 Expired - Fee Related CN1238706C (en) | 2003-11-06 | 2003-11-06 | Cross flow guiding type minisize static agitator |
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| Country | Link |
|---|---|
| CN (1) | CN1238706C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4939910B2 (en) | 2006-11-29 | 2012-05-30 | 株式会社東芝 | Micro chemical analysis system and micro chemical analysis device |
| CN101708439B (en) * | 2009-11-05 | 2012-04-25 | 浙江大学 | Chaotic microfluidic chip mixer and mixing method thereof |
| CN113842824B (en) * | 2021-10-15 | 2023-10-10 | 西安交通大学 | Passive micromixer for enhancing mixing efficiency based on composite side wall microstructure |
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2003
- 2003-11-06 CN CN 200310108539 patent/CN1238706C/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN1542429A (en) | 2004-11-03 |
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