CN1237936C - Electronic device for measuring blood-pressure - Google Patents
Electronic device for measuring blood-pressure Download PDFInfo
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- CN1237936C CN1237936C CN 03139708 CN03139708A CN1237936C CN 1237936 C CN1237936 C CN 1237936C CN 03139708 CN03139708 CN 03139708 CN 03139708 A CN03139708 A CN 03139708A CN 1237936 C CN1237936 C CN 1237936C
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Abstract
The present invention relates to an electronic non-wound device for measuring blood pressure. The cuff pulse wave signal processing algorithm for measuring blood pressure comprises the steps that a main program module invokes a program module for measuring blood pressure according to different measurement modes, and the inflation is carried out after starting; the cuff type is judged, and the step deflation is gradually carried out according to a preset deflation step mode when the pressure of a cuff reaches a preset target pressure; the corresponding adjustment is carried out according to the present cuff pressure and the deflation state, and the cuff pressure and the pulse waves on each step is detected synchronously; simultaneously, the states of measuring time, the variation of cuff pressure, etc. are detected and judged to determine the continuation or the abnormal termination of measurement; the step deflation process is stopped after the collected cuff pressure and the collected pulse waves reach a prospective target, and the measuring process is stopped normally; the stored pulse waves are interpolated, smoothed and fitted to obtain pulse waves and a sequence group of the corresponding cuff pressure; the cuff pressure corresponding to the pulse with the maximal amplitude is namely the mean pressure, and the mean pressure is firstly calculated by a proportionality factor method; the shrinking pressure and the diastolic pressure are calculated, and the result is notified to an upper machine.
Description
Technical field
The present invention relates to a kind ofly, and utilize inflator pump, vent valve, pressure transducer and corresponding electronics amplification and digital circuit and pulse wave signal Processing Algorithm to finish electronics Woundless blood pressure measuring device blood pressure measurement based on the cuff that is bundled in arm.
Background technology
Non-invasive blood pressure measuring method all is the oscillation method that adopts based on the cuff pulse wave.The non-invasive measurement method of human blood-pressure mainly contains auscultation (being called for short Ke Shi sound method) that utilizes the Ke Shi sound and the proportionality coefficient method (abbreviation succusion) of utilizing the cuff wave of oscillation.Ke Shi sound method is that experienced medical personnel adopt stethoscope, mercury pressure is taken into account cuff, the charge/discharge gas capsule is by being bundled in cuff the appropriate location of experimenter's upper arm, press close to brachial artery with stethoscope, inflate increase pressure up to the blood flow of blocking arm with the charge/discharge gas capsule to cuff, progressively lower cuff pressure to recover the blood flow of arm by the charge/discharge gas capsule then, one of the artery blood flow of arm pulsation meeting generation is ascending in this process, the descending again Ke Shi change of tuneization, and can listen to the variation of Ke Shi sound to determine systolic pressure and diastolic pressure by stethoscope and mercury gauge.Present most blood pressure measuring methods that have been to use based on succusion in electronic blood pressure measurement equipment, basic process and auscultation are very similar, promptly also boost to block the blood flow of arm by the cuff inflation, make the cuff deflation blood pressure lowering to recover the blood flow of arm then gradually, and the static pressure in the monitoring cuff and because of the pressure pulse wave that pulsation produced of arterial blood, but computational methods are by measuring pressure pulse wave and the corresponding cuff pressure thereof that artery blood flow pulsatile change at the deflation course arm is delivered in the cuff to be produced, can detect one group of amplitude from small to large, descending again pressure pulse involves corresponding descending cuff pressure, and be mean pressure with the corresponding cuff pressure of maximum of pressure pulse wave, (maximum of pressure pulse wave multiply by two two pairing cuff pressure of range value that obtain less than 1 coefficient and is respectively systolic pressure and diastolic pressure according to the amplitude proportional coefficient of the pressure pulse wave of empirical value again, as 0.7) come to press high direction to extrapolate systolic pressure to cuff, and extrapolate diastolic pressure (being called for short proportionality coefficient method) based on cuff vibration pulse magnitude to the direction that cuff forces down.The basic structure of electronic blood pressure measurement equipment generally comprises pressure transducer and the treatment circuit that () detects cuff pressure; (2) the pressure pulse wave treatment circuit that changes based on cuff pressure; (3) excess pressure detecting sensor and amplification, protection treatment circuit; (4) gas circuit and the control of filling, exit that are connected with pressure transducer of cuff, control vent valve, inflator pump; (5) mould/number conversion, Single Chip Microcomputer (SCM) system, (six) power pack.Wherein the detection of pressure pulse wave and cuff pressure can be placed on venting stage or aeration phase after the inflation in the measuring process, the venting form in venting stage can be evenly to exit continuously (promptly to successively decrease with the 3-5mmHg uniform pressure, while detected pressures pulse wave), also can be that (promptly the step with 5-10mmHg lowers cuff pressure one by one in the step venting, detected pressures pulse wave on each pressure step), the big young pathbreaker of each step hypotension presses to determine according to detected pulse wave amplitude and current cuff.Continuously even venting form will increase the time of blood pressure measurement process, the influence that arm motion, position are changed also is difficult to overcome, a little less than the anti-motion artifacts ability, its application is subjected to certain limitation, and step venting form will reduce the blood pressure measurement time, and can overcome because the interference of initiations such as arm motion, position variation possesses better anti-jamming capability, so a lot of company adopts step venting form mostly in blood pressure measurement.Its weak point is:
1. complicated, the nothing measurement gain control of pressure, pulse wave signal testing circuit.
2. the excess pressure holding circuit of reserve can not have two or more accurately overvoltages force to be provided with, and is bad to the adaptive capacity of pressure transducer.
Summary of the invention
The purpose of this invention is to overcome above-mentioned weak point of the prior art and a kind of module simulation Signal Processing circuit structure of having optimized is provided, improve the common mode of cuff pressure and pulsation wave circuit and face upward the system ability, thereby the gain control that increases the pulse wave circuit has improved the scope of application that the neonate blood pressure is measured, increasing a plurality of adjustable excess pressure protection points is provided with, improved the adaptability of excess pressure holding circuit, also increased the adaptive capacity of excess pressure holding circuit simultaneously pressure transducer to different desired use; Another object of the present invention is to cooperate hardware circuit to improve to have redesigned systems soft ware, finishes the electronics Woundless blood pressure measuring device based on the oscillation method of cuff pulse wave jointly.
Purpose of the present invention can reach by following measure: this electronics Woundless blood pressure measuring device; it has single-chip microcomputer and Peripheral storage and controller, analog digital conversion, cuff pressure amplifying circuit and pulse wave amplifying circuit, cuff and presses overvoltage crowbar; the gas circuit that links to each other with inflator pump with cuff pressure pick off, fast, slow vent valve; its special character is that described single-chip microcomputer and Peripheral storage and controller are carried out the measurement of pulse wave signal Processing Algorithm to blood pressure as follows:
(1) after system power-up, finish setting by at first calling initialize routine after the system loads to the conventional sense and the normal operating conditions of system hardware, further finish changing mastery routine over to, wait command after shaking hands with host computer;
(2) main program module is at any time in the current resulting order of inquiry, and according to next step the operation of this command execution, also can end current operation, returns main program module and recovers waiting state;
(3) finish transfer of data by serial ports between the upper and lower machine after, whether order is provided with replying to inquire about at any time has receive interior perhaps to need the data that send in the serial ports buffer memory, send or accept subroutine instruction in case have to start at once;
(4) measurement state and pattern conversion program module will be adjusted Set For Current state and measurement pattern according to current host computer order of receiving;
(5) the blood pressure measurement module is finished inflation, the venting to cuff, measures the analysis of status monitoring and judgement, cuff pressure and pulse wave and processing, finishes the calculating of blood pressure at last;
(6) data acquisition and preprocessor module are carried out the collection and the pretreatment of cuff pressure and pulse wave signal in real time, simultaneously pulse wave are carried out the identification of reference wave and calculating, the storage of amplitude;
(7) the error handler module will be returned different error message codes according to different error message inputs, and the reporting system mastery routine.
Main program module will be according to different measurement patterns, call blood pressure measurement control sequence module, at first carry out gas replenishment process after the startup, and during the course the cuff type is judged, after cuff pressure is charged to predetermined goal pressure, progressively carry out the step venting by predetermined venting step mode, and carry out the adjustment of deflated state according to current cuff pressure and deflated state, cuff pressure and pulse wave on each step of synchronous detecting, simultaneously also to current Measuring Time, states such as cuff pressure variation are monitored and are judged, confirm to measure and whether continue or abnormal end, after reaching the set goal, the cuff pressure that collects and pulse wave stop the step deflation course, the measuring process normal termination, pulse wave is carried out interpolation, smoothly, process of fitting treatment is at first calculated mean pressure according to the proportionality coefficient method at last, calculates and shrinks Asia and diastolic pressure, and with the result notification host computer, system returns mastery routine.
Purpose of the present invention can also reach by following measure:
The circuit of this device mainly comprises cuff pressure, the excess pressure holding circuit of pulse signal and signal deteching circuit and reserve, its cuff 1 respectively with first pressure transducer 2, second pressure transducer 9 links to each other, wherein main channel is that the output of first pressure transducer 2 is connected to the amplification that instrument amplifier 3 is finished static cuff pressure, leading up to of instrument amplifier 3 outfans directly received analog-digital converter 8 after suitable dividing potential drop and the filtering, realize the data acquisition of static cuff pressure, and after another road pulse wave of instrument amplifier 3 outfans is isolated through electric capacity 17, input to the anti-phase proportional amplifier 4 of two-stage, 5 realize that the signal of pulse wave amplifies, on rp-op amp 5, also connect simultaneously program control gain and selected 12, guarantee to be arranged with different gains, afterwards resultant pulse wave signal 6 is sent into the data acquisition that analog-digital converter 8 is finished pulse wave again in the different application pattern; The pressure detecting channel of reserve is made up of operational amplifier 100 and follow-up comparator 11 that pressure transducer 9 is connected; be used to detect cuff pressure and whether surpass predetermined protection pressure spot; guarantee experimenter's safety; wherein pressure transducer 9 is input to difference amplifier 10 with difference form; the amplifying circuit that this difference amplifier 10 is made up of two in-phase proportion amplifiers 100 with difference I/O; finish the amplification of static cuff pressure; two outfans of this amplifying circuit are connected respectively to two inputs of follow-up comparator 11; in-phase input end at this follow-up comparator 11 inserts a plurality of adjustable reference voltages 15 simultaneously; so just can realize the accurate status upset of a plurality of overvoltage point protections; to adapt to the demand that different over-voltage protection points are set without expectation under the application model; and the output state of follow-up comparator 11 changes and will be input to microprocessor 16 and do further processing; communication interface 21 is central microprocessor 16 and host computer contact channel; cuff 1 inserts quick release valve 14 respectively by the gas circuit adapter; slowly put valve 13; and quick release valve 14 and put valve 13 slowly and be subjected to central microprocessor 16 control by cut-in valve control circuit 19; air pump 18 also is to insert cuff 1 by the gas circuit adapter, again by inserting the control that pump control circuit 20 is subjected to central microprocessor 16.
The side circuit schematic diagram of above-mentioned block diagram specifically describes and is as shown in the figure:
The output of the pressure transducer S1 of main signal channel is through going between 1, lead-in wire 3 inserts the port 2 of instrument amplifier U4, port 3, the input lead 4 of pressure transducer S1 inserts the port one of operational amplifier U1, the lead-in wire 2 of pressure transducer S1 and lead-in wire 5 ports 3 that insert operational amplifier U1-1 in parallel, operational amplifier U1 pin 4 ground connection, pin 8 connects power Vcc and passes through capacitor C 1 ground connection AGND, pin 6 ground connection of pressure transducer S1, insert the pin 8 of instrument amplifier U4 behind the pin 1 connecting resistance R1 of instrument amplifier U4, the pin 7 of instrument amplifier U4 connects power Vcc, and by capacitor C 2 ground connection, pin 4 ground connection of instrument amplifier U4, the pin 5 of instrument amplifier U4 is connected on resistance R 2 and R3 simultaneously, the termination Vcc of R2 wherein, the end ground connection of R3,6 fens two-way of the output pin of instrument amplifier U4, potentiometer RW1 and the resistance R 4 polyphone dividing potential drops of leading up to output to resistance R 7, and connect capacitor C 4 to ground, node 120 is as sleeve output CuffPress with pressure simultaneously, another road connects resistance R 5 by capacitance C3, and be input to the pin 6 of operational amplifier U1-2 by R5, simultaneously tell one the tunnel and insert the pin 4 of analog switch U7 by resistance R 6 at capacitor C 3 and resistance R 5 nodes 60, and the pin 3 of analog switch U7 is connected to the pin 6 of operational amplifier U1-2, control by analog switch U7 realizes that resistance R 5 is in parallel with R6 or disconnects to finish the gain control to operational amplifier U1-2, the pin 9 of U7 connects the port of STEP from CPU, the pin 6 of operational amplifier U1-2 is connected with pin 7 with capacitor C 5 backs in parallel by resistance R 8, and pin 5 meets Vref1, the R9 of leading up to of the pin 7 of operational amplifier U1-2 inserts the pin 2 of operational amplifier U2-1, the pin 15 of analog switch U7 is inserted on another road by R10, and the pin 1 of analog switch U7 is connected to the pin 2 of operational amplifier U2-1, control by analog switch U7 realizes that resistance R 9 is in parallel with R10 or disconnects to finish the gain control to operational amplifier U2-1, the pin 2 of operational amplifier U2-1 inserts pin 1 by resistance R 11 and capacitor C 6 backs in parallel, operational amplifier U2-1 pin 4 ground connection, pin 8 connects power Vcc, and by C15 ground connection, pin 3 meets Vref2, the output pin 1 connecting resistance R12 of operational amplifier U2-1 is to the output of node 110 realization pulse waves, and node 110 is by capacitor C 7 ground connection.The overvoltage protection signalling channel is to import VI by R13 with power supply by the pin 1 of pressure transducer S2 to be connected; and node 180 is by stabilivolt D1 and capacitor C 10 ground connection AGND in parallel; the pin 3 of pressure transducer S2 is ground connection AGND also; the pin 4 of pressure transducer S2 is received the pin 3 of operational amplifier U3-1; the pin 2 of operational amplifier U3-1 is received pin 1 by resistance R 19; after also contacting with potentiometer RW3 by resistance R 18 simultaneously, this pin 2 is connected to the pin 6 of operational amplifier U3-2; the pin 2 of pressure transducer S2 is received the pin 6 of operational amplifier U3-2; this pin 6 is received pin 7 by resistance R 20; the pin 1 of operational amplifier U3 is connected to the pin 6 of operational amplifier U2-2 by resistance R 21; pin 6 is connected to the pin 14 of analog switch U7 again by resistance R 23; and further the pin 13 or 12 by U7 is connected respectively to reference voltage V1.25 and V2.5; the pin 7 of operational amplifier U3-2 is connected with the pin 5 of operational amplifier U2-2 by R22; the pin 5 of operational amplifier U2-2 is connected with pin 7 with ground GND respectively with resistance R 25 by resistance R 24 again simultaneously; link to each other by capacitor C 13 between the pin 5 of operational amplifier U2-2 and the pin 6; the pin 7 of operational amplifier U2-2 is connected with the pin 1 of field effect transistor Q1 by resistance R 26; the pin 1 of field effect transistor Q1 is connected with pin 2 by resistance R 27 again; and connect with ground AGND; the pin 3 of field effect transistor Q1 is connected with power Vcc by resistance R 28, and this pin 3 also is the output port of overvoltage condition simultaneously.
The U7 pin 15 of analog switching circuit connects power Vcc, pin 7,8 and pin 6 ground connection AGND, it is a port from CPU that pin 9 meets STEPJ, to finish being connected and disconnection to pin 4 and pin 3 or pin 5, being connected to AN_MODE after pin 10 and pin 11 parallel connections is from port of CPU, be connected to pin 1 or pin 2 to finish pin 15, pin 14 is connected to the synchronous switching of pin 13 or pin 12.
The present invention has following advantage compared to existing technology:
1. optimize the structure of cuff pressure and pulse wave testing circuit, improve the ability of the common mode rejection ratio of circuit, the gain setting that increases circuit can improve neonatal blood pressure measurement subject range.
2. optimized the adaptive capacity of overvoltage crowbar to pressure transducer, realized the accurate setting of a plurality of excess pressure point protections, intensifier circuit is to the safety assurance of the overvoltage protection of different application scope.
Description of drawings
Fig. 1 is the block diagram of main circuit structure of the present invention.
Fig. 2 is the block diagram of explanation digital computer CPU elementary cell.
Fig. 3 is the system block diagram of explanation most preferred embodiment of the present invention.
Fig. 4 is a circuit diagram of the present invention.
The specific embodiment
The present invention is further detailed in conjunction with the accompanying drawings below:
See also shown in Figure 1, the circuit structure of this contrive equipment mainly comprises cuff pressure, pulse signal, signal deteching circuit, the excess pressure holding circuit of reserve, inflator pump and vent valve control circuit, critical pieces such as analog digital conversion and digital display circuit circuit, wherein concrete signal path: cuff 1 respectively with first pressure transducer 2, second pressure transducer 9 links to each other, wherein main channel is that the output of first pressure transducer 2 is connected to the amplification that instrument amplifier 3 is finished static cuff pressure, leading up to of instrument amplifier 3 outfans directly received analog-digital converter 8 after suitable dividing potential drop and the filtering, realize the data acquisition of static cuff pressure, and after another road pulse wave of instrument amplifier 3 outfans is isolated through electric capacity 17, input to the anti-phase proportional amplifier 4 of two-stage, 5 realize that the signal of pulse wave amplifies, on rp-op amp 5, also connect simultaneously program control gain and selected 12, guarantee that (adult/neonate) is provided with different gains under the different application pattern, afterwards resultant pulse wave signal 6 is sent into analog-digital converter 8 again, finish the data acquisition of pulse wave; The pressure detecting channel of reserve is made up of operational amplifier 100 and follow-up comparator 11 that second pressure transducer 9 is connected; be used to detect cuff pressure and whether surpass predetermined protection pressure spot; guarantee experimenter's safety; wherein pressure transducer 9 is input to difference amplifier 10 with difference form; the amplifying circuit that this difference amplifier 10 is made up of two in-phase proportion amplifiers 100 with difference I/O; finish the amplification of static cuff pressure; two outfans of this amplifying circuit are connected respectively to two inputs of follow-up comparator 11; in-phase input end at this follow-up comparator 11 inserts a plurality of adjustable reference voltages 15 simultaneously; so just can realize the accurate status upset of a plurality of overvoltage point protections; to adapt to the demand that different over-voltage protection points are set without expectation under the application model; and the output state of follow-up comparator 11 changes and will be input to microprocessor 16 and do further processing; communication interface 21 is central microprocessor 16 and host computer contact channel; cuff 1 inserts quick release valve 14 respectively by the gas circuit adapter; slowly put valve 13; and quick release valve 14 and put valve 13 slowly and be subjected to central microprocessor 16 control by cut-in valve control circuit 19; air pump 18 also is to insert cuff 1 by the gas circuit adapter, again by inserting the control that pump control circuit 20 is subjected to central microprocessor 16.
The output of the pressure transducer S1 of main signal channel is through going between 1, lead-in wire 3 inserts the port 2 of instrument amplifier U4, port 3, the input lead 4 of pressure transducer S1 inserts the port one of operational amplifier U1, the lead-in wire 2 of pressure transducer S1 and lead-in wire 5 ports 3 that insert operational amplifier U1-1 in parallel, operational amplifier U1 pin 4 ground connection, pin 8 connects power Vcc and passes through capacitor C 1 ground connection AGND, pin 6 ground connection of pressure transducer S1, insert the pin 8 of instrument amplifier U4 behind the pin 1 connecting resistance R1 of instrument amplifier U4, the pin 7 of instrument amplifier U4 connects power Vcc, and by capacitor C 2 ground connection, pin 4 ground connection of instrument amplifier U4, the pin 5 of instrument amplifier U4 is connected on resistance R 2 and R3 simultaneously, the termination Vcc of R2 wherein, the end ground connection of R3,6 fens two-way of the output pin of instrument amplifier U4, potentiometer RW1 and the resistance R 4 polyphone dividing potential drops of leading up to output to resistance R 7, and connect capacitor C 4 to ground, node 120 is as sleeve output CuffPress with pressure simultaneously, another road connects resistance R 5 by capacitance C3, and be input to the pin 6 of operational amplifier U1-2 by R5, simultaneously tell one the tunnel and insert the pin 4 of analog switch U7 by resistance R 6 at capacitor C 3 and resistance R 5 nodes 60, and the pin 3 of analog switch U7 is connected to the pin 6 of operational amplifier U1-2, control by analog switch U7 realizes that resistance R 5 is in parallel with R6 or disconnects to finish the gain control to operational amplifier U1-2, the pin 9 of U7 connects the port of STEP from CPU, the pin 6 of operational amplifier U1-2 is connected with pin 7 with capacitor C 5 backs in parallel by resistance R 8, and pin 5 meets Vref1, the R9 of leading up to of the pin 7 of operational amplifier U1-2 inserts the pin 2 of operational amplifier U2-1, the pin 15 of analog switch U7 is inserted on another road by R10, and the pin 1 of analog switch U7 is connected to the pin 2 of operational amplifier U2-1, control by analog switch U7 realizes that resistance R 9 is in parallel with R10 or disconnects to finish the gain control to operational amplifier U2-1, the pin 2 of operational amplifier U2-1 inserts pin 1 by resistance R 11 and capacitor C 6 backs in parallel, operational amplifier U2-1 pin 4 ground connection, pin 8 connects power Vcc, and by C15 ground connection, pin 3 meets Vref2, the output pin 1 connecting resistance R12 of operational amplifier U2-1 is to the output of node 110 realization pulse waves, and node 110 is by capacitor C 7 ground connection.
See also shown in Figure 4; the overvoltage protection signalling channel is to import VI by R13 with power supply by the pin 1 of pressure transducer S2 to be connected; and node 180 is by stabilivolt D1 and capacitor C 10 ground connection AGND in parallel; the pin 3 of pressure transducer S2 is ground connection AGND also; the pin 4 of pressure transducer S2 is received the pin 3 of operational amplifier U3-1; the pin 2 of operational amplifier U3-1 is received pin 1 by resistance R 19; after also contacting with potentiometer RW3 by resistance R 18 simultaneously, this pin 2 is connected to the pin 6 of operational amplifier U3-2; the pin 2 of pressure transducer S2 is received the pin 6 of operational amplifier U3-2; this pin 6 is received pin 7 by resistance R 20; the pin 1 of operational amplifier U3 is connected to the pin 6 of operational amplifier U2-2 by resistance R 21; pin 6 is connected to the pin 14 of analog switch U7 again by resistance R 23; and further the pin 13 or 12 by U7 is connected respectively to reference voltage V1.25 and V2.5; the pin 7 of operational amplifier U3-2 is connected with the pin 5 of operational amplifier U2-2 by R22; the pin 5 of operational amplifier U2-2 is connected with pin 7 with ground GND respectively with resistance R 25 by resistance R 24 again simultaneously; link to each other by capacitor C 13 between the pin 5 of operational amplifier U2-2 and the pin 6; the pin 7 of operational amplifier U2-2 is connected with the pin 1 of field effect transistor Q1 by resistance R 26; the pin 1 of field effect transistor Q1 is connected with pin 2 by resistance R 27 again; and connect with ground AGND; the pin 3 of field effect transistor Q1 is connected with power Vcc by resistance R 28, and this pin 3 also is the output port of overvoltage condition simultaneously.
In addition, the U7 pin 15 of analog switching circuit connects power Vcc, pin 7,8 and pin 6 ground connection AGND, it is a port from CPU that pin 9 meets STEPJ, to finish being connected and disconnection to pin 4 and pin 3 or pin 5, being connected to AN_MODE after pin 10 and pin 11 parallel connections is from port of CPU, is connected to pin 1 or pin 2 to finish pin 15, and pin 14 is connected to the synchronous switching of pin 13 or pin 12.
Be the electric power system of foregoing circuit at last, extraneous input power supply VI, insert the pin 3 of three terminal regulator U5, the pin 2 ground connection AGNG of U5, the pin 1 of U5 is by capacitor C 8, ground connection after the C9 parallel connection, also be the output Vcc of power supply simultaneously, the application of all Vcc is provided, the pin 1 of accurate voltage stabilizing benchmark U6 meets Vcc, link to each other with ground by capacitor C 11 simultaneously, be attempted by on the pin 3, the pin 2 of U6 is the output of benchmark V2.5, and is divided into two-way, one the tunnel is by resistance R 14, R15, R16, R17 polyphone back ground connection, form benchmark Verf1, Vref2, Vref3, another road is by capacitor C 12, ground connection after the potentiometer RW2 parallel connection, wherein the centre tap of RW2 divides extrusion benchmark V1.25.
Fig. 2, Fig. 3 have illustrated that the present invention operates the flow chart of algorithm.
See also Fig. 2, the pulse wave signal Processing Algorithm is carried out following steps to blood pressure measurement:
(1) after system power-up, finish setting by at first calling initialize routine after the system loads to the conventional sense and the normal operating conditions of system hardware, further finish changing mastery routine over to, wait command after shaking hands with host computer;
(2) main program module is at any time in the current resulting order of inquiry, and according to next step the operation of this command execution, also can end current operation, returns main program module and recovers waiting state;
(3) the serial communication program module is finished transfer of data between the upper and lower machine by serial ports, and whether order is provided with replying to inquire about at any time has receive interior perhaps to need the data that send in the serial ports buffer memory, send or accept subroutine instruction in case have to start at once;
(4) measurement state and pattern conversion program module will be adjusted Set For Current state and measurement pattern according to current host computer order of receiving;
(5) the blood pressure measurement module is finished inflation, the venting to cuff, measures the analysis of status monitoring and judgement, cuff pressure and pulse wave and processing, finishes the calculating of blood pressure at last;
(6) data acquisition and preprocessor module are carried out the collection and the pretreatment of cuff pressure and pulse wave signal in real time, simultaneously pulse wave are carried out the identification of reference wave and calculating, the storage of amplitude;
(7) the error handler module will be returned different error message codes according to different error message inputs, and the reporting system mastery routine.
The indication of the flow chart of Fig. 3 at first starts inflator pump 101 when beginning blood pressure measurement 100, processor is carried out determining step 102, reaches not to judge predeterminated target pressure, if judge whether surely, then carries out 101 startup inflator pump steps; If judge it is sure, then execution in step 103, start vent valve and begin the step venting; Enter step 104, transfinite to judge predetermined step deflation time? if judge it is sure, then execution in step 105, promptly measure and finish and the returning pressure abnormal information; If it is fixed to judge whether, then execution in step 106, to judge that next goal pressure reaches not? if judge negate, then execution in step 107, to judge that current cuff pressure is less than goal pressure? if judge it is sure, then execution in step 108, enter step 103 subsequently, if judge whether the fixed step 103 that enters too, judge to be sure then execution in step 109 if enter step 106, promptly gather cuff pressure and discern effective benchmark Pulse Rate with corresponding pulse wave, enter step 110 subsequently, to judge that the pulse wave of gathering and storing satisfies the pulse wave calculation requirement of certain step? if it is fixed to judge whether, then execution in step 109, if judge is sure then execution in step 111, transfinite this total time of then measuring to judge? if judge it is sure, then execution in step 112, promptly measure the abnormal results and return time-out information, if judge whether surely, then execution in step 113, to judge that the step venting finishes? if it is fixed to judge whether, then execution in step 103, if judge it is sure, then execution in step 114, calculate mean pressure, systolic pressure, diastolic pressure is measured normal termination.
Claims (6)
1. electronics Woundless blood pressure measuring device; it has single-chip microcomputer and Peripheral storage and controller, analog digital conversion, cuff pressure amplifying circuit and pulse wave amplifying circuit, cuff and presses overvoltage crowbar; the gas circuit that links to each other with inflator pump with cuff pressure pick off, fast, slow vent valve; it is characterized in that described single-chip microcomputer and Peripheral storage and controller are carried out the measurement of pulse wave signal Processing Algorithm to blood pressure as follows:
(1) after system power-up, finish setting by at first calling initialize routine after the system loads to the conventional sense and the normal operating conditions of system hardware, further finish changing mastery routine over to, wait command after shaking hands with host computer;
(2) main program module is at any time in the current resulting order of inquiry, and according to next step the operation of this command execution, also can end current operation, returns main program module and recovers waiting state;
(3) finish transfer of data by serial ports between the upper and lower machine after, whether order is provided with replying to inquire about at any time has receive interior perhaps to need the data that send in the serial ports buffer memory, send or accept subroutine instruction in case have to start at once;
(4) measurement state and pattern conversion program module will be adjusted Set For Current state and measurement pattern according to current host computer order of receiving;
(5) the blood pressure measurement module is finished inflation, the venting to cuff, measures the analysis of status monitoring and judgement, cuff pressure and pulse wave and processing, finishes the calculating of blood pressure at last;
(6) data acquisition and preprocessor module are carried out the collection and the pretreatment of cuff pressure and pulse wave signal in real time, simultaneously pulse wave are carried out the identification of reference wave and calculating, the storage of amplitude;
(7) the error handler module will be returned different error message codes according to different error message inputs, and the reporting system mastery routine.
2. electronics Woundless blood pressure measuring device according to claim 1, it is characterized in that: the circuit of this device mainly comprises cuff pressure, the excess pressure holding circuit of pulse signal and signal deteching circuit and reserve, its cuff [1] respectively with first pressure transducer [2], second pressure transducer [9] links to each other, wherein main channel is that the output of first pressure transducer [2] is connected to the amplification that instrument amplifier [3] is finished static cuff pressure, leading up to of instrument amplifier [3] outfan directly received analog-digital converter [8] after suitable dividing potential drop and the filtering, realize the data acquisition of static cuff pressure, and after another road pulse wave of instrument amplifier [3] outfan is isolated through electric capacity [17], input to the anti-phase proportional amplifier of two-stage [4], [5] signal of realizing pulse wave amplifies, on rp-op amp [5], also connected simultaneously program control gain and selected [12], guarantee to be arranged with different gains in the different application pattern, afterwards resultant pulse wave signal [6] is sent into analog-digital converter [8] again, finish the data acquisition of pulse wave; The pressure detecting channel of reserve is made up of operational amplifier [100] and follow-up comparator [11] that second pressure transducer [9] is connected; be used to detect cuff pressure and whether surpass predetermined protection pressure spot; guarantee experimenter's safety; wherein second pressure transducer [9] is input to difference amplifier [10] with difference form; the amplifying circuit that this difference amplifier [10] is made up of two in-phase proportion amplifiers [100] with difference I/O; finish the amplification of static cuff pressure; two outfans of this amplifying circuit are connected respectively to two inputs of follow-up comparator [11]; in-phase input end at this follow-up comparator [11] inserts a plurality of adjustable reference voltages [15] simultaneously; so just can realize the accurate status upset of a plurality of overvoltage point protections; to adapt to the demand that different over-voltage protection points are set without expectation under the application model; and the output state of follow-up comparator [11] changes and will be input to microprocessor [16] and do further processing; communication interface [21] is central microprocessor [16] and host computer contact channel; cuff [1] inserts quick release valve [14] respectively by the gas circuit adapter; slowly put valve [13]; and quick release valve [14] and put valve [13] slowly and be subjected to central microprocessor [16] control by cut-in valve control circuit [19]; air pump [18] also is to insert cuff [1] by the gas circuit adapter, again by inserting the control that pump control circuit [20] is subjected to central microprocessor [16].
3. electronics Woundless blood pressure measuring device according to claim 1, it is characterized in that: main program module will be according to different measurement patterns, call blood pressure measurement control sequence module, at first carry out gas replenishment process after the startup, and during the course the cuff type is judged, after cuff pressure is charged to predetermined goal pressure, progressively carry out the step venting by predetermined venting step mode, and carry out the adjustment of deflated state according to current cuff pressure and deflated state, cuff pressure and pulse wave on each step of synchronous detecting, simultaneously also to current Measuring Time, states such as cuff pressure variation are monitored and are judged, confirm to measure and whether continue or abnormal end, stop the step deflation course after the cuff pressure that collects and pulse wave reach the set goal, the measuring process normal termination is carried out interpolation to pulse wave, smoothly, process of fitting treatment, at first calculate mean pressure according to the proportionality coefficient method at last, calculate again and shrink Asia and diastolic pressure, and with the result notification host computer, system returns mastery routine.
4. electronics Woundless blood pressure measuring device according to claim 1 is characterized in that: the output of the pressure transducer S1 of main signal channel is through the port 2, the port 3 that go between 1, lead-in wire 3 inserts instrument amplifier U4, pressure transducer S
1Input lead 4 insert the port one of operational amplifier U1, the lead-in wire 2 of pressure transducer S1 and lead-in wire 5 ports 3 that insert operational amplifier U1-1 in parallel, operational amplifier U1 pin 4 ground connection, pin 8 connects power Vcc and passes through capacitor C 1 ground connection AGND, pin 6 ground connection of pressure transducer S1, insert the pin 8 of instrument amplifier U4 behind the pin 1 connecting resistance R1 of instrument amplifier U4, the pin 7 of instrument amplifier U4 connects power Vcc, and by capacitor C 2 ground connection, pin 4 ground connection of instrument amplifier U4, the pin 5 of instrument amplifier U4 is connected on resistance R 2 and R3 simultaneously, the termination Vcc of R2 wherein, the end ground connection of R3,6 fens two-way of the output pin of instrument amplifier U4, potentiometer RW1 and the resistance R 4 polyphone dividing potential drops of leading up to output to resistance R 7, and connect capacitor C 4 to ground, node 120 is as sleeve output CuffPress with pressure simultaneously, another road connects resistance R 5 by capacitance C3, and be input to the pin 6 of operational amplifier U1-2 by R5, simultaneously tell one the tunnel and insert the pin 4 of analog switch U7 by resistance R 6 at capacitor C 3 and resistance R 5 nodes 60, and the pin 3 of analog switch U7 is connected to the pin 6 of operational amplifier U1-2, control by analog switch U7 realizes that resistance R 5 is in parallel with R6 or disconnects to finish the gain control to operational amplifier U1-2, the pin 9 of U7 connects the port of STEP from central microprocessor, the pin 6 of operational amplifier U1-2 is connected with pin 7 with capacitor C 5 backs in parallel by resistance R 8, and pin 5 meets Vref1, the R9 of leading up to of the pin 7 of operational amplifier U1-2 inserts the pin 2 of operational amplifier U2-1, the pin 15 of analog switch U7 is inserted on another road by R10, and the pin 1 of analog switch U7 is connected to the pin 2 of operational amplifier U2-1, control by analog switch U7 realizes that resistance R 9 is in parallel with R10 or disconnects to finish the gain control to operational amplifier U2-1, the pin 2 of operational amplifier U2-1 inserts pin 1 by resistance R 11 and capacitor C 6 backs in parallel, operational amplifier U2-1 pin 4 ground connection, pin 8 connects power Vcc, and by C15 ground connection, pin 3 meets Vref2, the output pin 1 connecting resistance R12 of operational amplifier U2-1 is to the output of node 110 realization pulse waves, and node 110 is by capacitor C 7 ground connection.
5. electronics Woundless blood pressure measuring device according to claim 1; it is characterized in that: the overvoltage protection signalling channel is to import VI by R13 with power supply by the pin 1 of pressure transducer S2 to be connected; and node 180 is by stabilivolt D1 and capacitor C 10 ground connection AGND in parallel; the pin 3 of pressure transducer S2 is ground connection AGND also; the pin 4 of pressure transducer S2 is received the pin 3 of operational amplifier U3-1; the pin 2 of operational amplifier U3-1 is received pin 1 by resistance R 19; after also contacting with potentiometer RW3 by resistance R 18 simultaneously, this pin 2 is connected to the pin 6 of operational amplifier U3-2; the pin 2 of pressure transducer S2 is received the pin 6 of operational amplifier U3-2; this pin 6 is received pin 7 by resistance R 20; the pin 1 of operational amplifier U3 is connected to the pin 6 of operational amplifier U2-2 by resistance R 21; pin 6 is connected to the pin 14 of analog switch U7 again by resistance R 23; and further the pin 13 or 12 by U7 is connected respectively to reference voltage V1.25 and V2.5; the pin 7 of operational amplifier U3-2 is connected with the pin 5 of operational amplifier U2-2 by R22; the pin 5 of operational amplifier U2-2 is connected with pin 7 with ground GND respectively with resistance R 25 by resistance R 24 again simultaneously; link to each other by capacitor C 13 between the pin 5 of operational amplifier U2-2 and the pin 6; the pin 7 of operational amplifier U2-2 is connected with the pin 1 of field effect transistor Q1 by resistance R 26; the pin 1 of field effect transistor Q1 is connected with pin 2 by resistance R 27 again; and connect with ground AGND; the pin 3 of field effect transistor Q1 is connected with power Vcc by resistance R 28, and this pin 3 also is the output port of overvoltage condition simultaneously.
6. electronics Woundless blood pressure measuring device according to claim 1, it is characterized in that: the U7 pin 15 of analog switching circuit connects power Vcc, pin 7,8 and pin 6 ground connection AGND, it is a port from central microprocessor that pin 9 meets STEPJ, to finish being connected and disconnection to pin 4 and pin 3 or pin 5, being connected to AN_MODE after pin 10 and pin 11 parallel connections is from port of central microprocessor, be connected to pin 1 or pin 2 to finish pin 15, pin 14 is connected to the synchronous switching of pin 13 or pin 12.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03139708 CN1237936C (en) | 2003-07-07 | 2003-07-07 | Electronic device for measuring blood-pressure |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03139708 CN1237936C (en) | 2003-07-07 | 2003-07-07 | Electronic device for measuring blood-pressure |
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| CN1513417A CN1513417A (en) | 2004-07-21 |
| CN1237936C true CN1237936C (en) | 2006-01-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 03139708 Expired - Lifetime CN1237936C (en) | 2003-07-07 | 2003-07-07 | Electronic device for measuring blood-pressure |
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| CN101125079B (en) * | 2006-08-16 | 2011-10-19 | 通用电气公司 | System of determining nibp target inflation pressure using an sp02 plethysmograph signal |
| CN101897580A (en) * | 2010-08-17 | 2010-12-01 | 上海三埃弗电子有限公司 | Device for blood pressure simultaneous measurement of limbs |
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| CN1513417A (en) | 2004-07-21 |
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