CN1236641A - Process for preparing onychomycosis ointment - Google Patents
Process for preparing onychomycosis ointment Download PDFInfo
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- CN1236641A CN1236641A CN 99114874 CN99114874A CN1236641A CN 1236641 A CN1236641 A CN 1236641A CN 99114874 CN99114874 CN 99114874 CN 99114874 A CN99114874 A CN 99114874A CN 1236641 A CN1236641 A CN 1236641A
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- onychomycosis
- onychomycosis ointment
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Abstract
An ointment for treating onychomycosis is prepared from garden balsam (5-10%), urea (10-40%), vaseline (5-25%), resorcinol (5-10%), tinctura corticis hibsci (10-30%), lactic acid (10-30%) and salicylic acid (8-30%) through crushing and mixing, and features simple preparing process, low cost, convenient application, high and quick curative effect and no toxic by-effect.
Description
The present invention is a kind of preparation method of onychomycosis ointment, belongs to medical preparing technical field.
Tinea unguium is a kind of common frdquently encountered disease, especially in China southwest that has a humid climate, as Sichuan, Yunnan, Guangdong, Guangxi and other places, though onychomycosis is sick little, brings a lot of inconvenience to people's work, life, social activity, causes the body and mind misery.Late nineteen eighties, people mainly adopt griseofulvin for oral administration and package to dial two kinds of method treatments of first to tinea unguium, and griseofulvin for oral administration all has untoward reaction and side effect to Most patients, and it is totally unfavorable to the patient that package is dialled first.The nineties initial stage, the Chinese patent application of CN1063820A has openly been reported a kind of manufacture method of tinea unguium dissolving cream, its prescription is by nine flavor mineral Chinese medicines such as Plumbum preparatium, seven flavor vegetalitas Chinese medicines such as white Flos Impatientis, oxybenzoic acid Western medicine and other more than ten kinds of materials are formed, it is various to fill a prescription, and preparation is complicated.
The objective of the invention is to develop a kind of prescription refine, the simple cost of technology is low, and onychomycosis ointment easy to use makes it remove the disease first in a short time, has no side effect again.
The objective of the invention is (following content is percetage by weight) of realizing by following proposal.
Onychomycosis ointment of the present invention is by Flos Impatientis 5%～10%, carbamide 10%～40%, vaseline 5%～25%, resorcin 5%～10%, Cortex Pseudolaricis tincture 10%～30%, lactic acid 10%～30%, salicylic acid 8%～30% mixes, remix after the coarse granule raw material need drying and crushing wherein.
In the such scheme, also can add Radix Sophorae Flavescentis and/or Oleum Bulbus Allii, addition is 5%～8%.
In the such scheme, better be with Flos Impatientis, add the Oleum Bulbus Allii mixing after Radix Sophorae Flavescentis is pulverized and mixed and get I, with carbamide, resorcin, salicylic acid pulverize mix II, with Cortex Pseudolaricis tincture, lactic acid mix III, with I add the II mixing add again mix in the III IV, with vaseline be heated to 40～60 ℃ add in the IV mixing packing get final product the product onychomycosis ointment.
The particle diameter of I is preferably and is controlled in 100～120 order scopes in the such scheme.
In the such scheme, also can add other additives.
The onychomycosis ointment of method for preparing also can be used in other field of medicaments beyond the treatment tinea unguium.
The onychomycosis ointment that the present invention makes, fungus killing power is strong, and is little to skin irritation, has no side effect, and is coated in the affected part and can removes the disease first in a short time.Scheme of the present invention, prescription refine, operating procedure is easy, low cost of manufacture, patient are used very convenient.
Embodiment one
Get Flos Impatientis 9 grams, carbamide 25 grams, vaseline 15 grams, resorcin 10 grams, Cortex Pseudolaricis tincture 24 grams, lactic acid 28 grams, salicylic acid 25 grams are wherein pulverized behind the coarse granule raw material drying and are mixed, and stir, and packing promptly gets the product onychomycosis ointment.
Embodiment two
With Flos Impatientis 10 grams, carbamide 20 grams, vaseline 20 grams, resorcin 8 grams, Cortex Pseudolaricis tincture 20 grams, lactic acid 20 grams, salicylic acid 18 grams weigh up, and weigh up Radix Sophorae Flavescentis 8 grams again, and the mixing of materials with after the above-mentioned drying and crushing stirs, and packing promptly gets the product onychomycosis ointment.
Embodiment three
Except that adding Oleum Bulbus Allii 8 grams, all the other are operated with embodiment two.
Embodiment four
With Flos Impatientis 10 grams, Radix Sophorae Flavescentis 9 grams weigh up and are ground into 100～120 purpose microgranules, and fully the abundant again mixing of mixing adding Oleum Bulbus Allii 10 grams makes I, with carbamide 30 grams, resorcin 9 grams, salicylic acid 20 grams weigh up back powder beading, the fully mixed II that gets, with Cortex Pseudolaricis tincture 25 grams, the mixed III that gets of lactic acid 23 grams, I added add in the III fully mixedly that IV is standby after II stirs again, vaseline is heated to 50 ℃ adds then in the IV, fully mix promptly getting the product onychomycosis ointment.
Claims (6)
1. the preparation method of an onychomycosis ointment, it is characterized in that it being Flos Impatientis 5%～10% (percetage by weight) just, carbamide 10%～40%, vaseline 5%～25%, resorcin 5%～10%, Cortex Pseudolaricis tincture 10%～30%, lactic acid 10%～30%, salicylic acid 8%～30% is pulverized mixing and is made onychomycosis ointment.
2. the preparation method of a kind of onychomycosis ointment according to claim 1 is characterized in that adding Radix Sophorae Flavescentis and/or Oleum Bulbus Allii again, and addition is 5%～8%.
3. the preparation method of a kind of onychomycosis ointment according to claim 1 and 2, it is characterized in that Flos Impatientis, add the Oleum Bulbus Allii mixing after Radix Sophorae Flavescentis is pulverized and mixed and get I, with carbamide, resorcin, salicylic acid pulverize mix II, with Cortex Pseudolaricis tincture, lactic acid mix III, with I add the II mixing add again mix in the III IV, vaseline is heated to 40～60 ℃ adds that the mixing packing promptly gets product in the IV.
4. the preparation method of a kind of onychomycosis ointment according to claim 3 is characterized in that the particle diameter of I is preferably 100～120 orders.
5. the preparation method of a kind of onychomycosis ointment according to claim 3 is characterized in that also can adding other additives.
6. according to the application of the onychomycosis ointment of the described method of claim 1～6 preparation at field of medicaments.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99114874A CN1090961C (en) | 1999-05-19 | 1999-05-19 | Process for preparing onychomycosis ointment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99114874A CN1090961C (en) | 1999-05-19 | 1999-05-19 | Process for preparing onychomycosis ointment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1236641A true CN1236641A (en) | 1999-12-01 |
| CN1090961C CN1090961C (en) | 2002-09-18 |
Family
ID=5277909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99114874A Expired - Fee Related CN1090961C (en) | 1999-05-19 | 1999-05-19 | Process for preparing onychomycosis ointment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1090961C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100408081C (en) * | 2005-11-24 | 2008-08-06 | 高飞 | Anti-tumor cancer-diminishing medicine and preparing method |
| CN103372061A (en) * | 2012-04-19 | 2013-10-30 | 孙桂华 | Traditional Chinese medicine ointment for treating leuconychia |
| CN103565914A (en) * | 2013-10-08 | 2014-02-12 | 高仓志 | Combined mixture of traditional Chinese and Western medicine for treating onychomycosis and paronychia |
| CN107519236A (en) * | 2017-09-12 | 2017-12-29 | 安徽世龙生物医药科技有限公司 | A kind of topical agent for treating onychomycosis |
| CN110833574A (en) * | 2018-08-16 | 2020-02-25 | 安徽世龙生物医药科技有限公司 | External preparation and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063820A (en) * | 1991-01-30 | 1992-08-26 | 樊芝芹 | The manufacture method of tinea unguium dissolving cream |
| CN1040839C (en) * | 1993-03-06 | 1998-11-25 | 青岛海洋大学 | Manicure composition |
-
1999
- 1999-05-19 CN CN99114874A patent/CN1090961C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100408081C (en) * | 2005-11-24 | 2008-08-06 | 高飞 | Anti-tumor cancer-diminishing medicine and preparing method |
| CN103372061A (en) * | 2012-04-19 | 2013-10-30 | 孙桂华 | Traditional Chinese medicine ointment for treating leuconychia |
| CN103565914A (en) * | 2013-10-08 | 2014-02-12 | 高仓志 | Combined mixture of traditional Chinese and Western medicine for treating onychomycosis and paronychia |
| CN107519236A (en) * | 2017-09-12 | 2017-12-29 | 安徽世龙生物医药科技有限公司 | A kind of topical agent for treating onychomycosis |
| CN110833574A (en) * | 2018-08-16 | 2020-02-25 | 安徽世龙生物医药科技有限公司 | External preparation and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1090961C (en) | 2002-09-18 |
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