CN1236542A - Application of isothiazolinone derivatives - Google Patents
Application of isothiazolinone derivatives Download PDFInfo
- Publication number
- CN1236542A CN1236542A CN 99106088 CN99106088A CN1236542A CN 1236542 A CN1236542 A CN 1236542A CN 99106088 CN99106088 CN 99106088 CN 99106088 A CN99106088 A CN 99106088A CN 1236542 A CN1236542 A CN 1236542A
- Authority
- CN
- China
- Prior art keywords
- dilution
- fruit
- isothiazolinone derivatives
- application
- reactor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
An application method of isothiazolinone derivatives as disinfectant of crops and auxiliary antistaling agent of fruit includes such steps as diluting it to become diluted solution (1-300 PPM) and spraying it onto the seeds, leaves, stem, bud, ears or fruit of crops. It can kill mang kinds of bacteria and elongate the antistaling period up to 90 days or longer. It features no odour and degradable residual.
Description
The invention belongs to a kind of application of isothiazolinone derivatives, particularly in auxiliary fresh-keeping application as crop bactericide or fruit.
The isothiazolinone derivatives bactericide is non-oxidizable bactericide, belongs to the high-efficiency broad spectrum bactericide.The sterilization algae removal that is widely used in industrial circulating water, oil underground water-injection, leather tanning, paper making pulp and plain boiled water circulation from the eighties.The isothiazolinone derivatives bactericide does not pollute environment, and its small amount of residue can natural degradation, can be called green bactericide.
Effective ingredient: A: B=3: in 1 formula: A is 5-chloro-2-methyl-4-isothiazoline-3-ketone
B is that the chemical structural formula of 2-methyl-4-isothiazoline-3-ketone A is:
The chemical structural formula of B is:
At present modal have A+B 〉=1.5% product, and the product of A+B 〉=14% or other specification is also arranged, and still do not have unified analytical standard, and the analysis way has chemical analysis and the existing open report of chromatography.
Main purpose of the present invention is that isothiazolinone derivatives is applied on the crops as bactericide, and through this bactericide sterilizing rate height of research evidence obtaining for many years, bactericidal range is wide, and pollution-free.
Another goal of the invention of the present invention is that isothiazolinone derivatives is assisted fresh-keeping application as fruit, and it can prolong storage period more than 90 days under refrigerated condition.
Of the present invention with the application of isothiazolinone derivatives as crop bactericide, its key step comprises: 1) get a kind of different azoles thiophene quinoline ketone derivatives, its active ingredient is:
A: B=3: in 1 formula: A is 5-chloro-2-methyl-4-isothiazoline-3-ketone
B is that the chemical structural formula of 2-methyl-4-isothiazoline-3-ketone A is:
The chemical structural formula of B is:
2) adopt enamel reaction still or plastics reactor, and add distilled water, deionized water, underground water or clean tap water; 3) with 1) in isothiazolinone derivatives add in the reactor, and dilution is the dilution of 1～300PPM; 4) above-mentioned dilution is sprayed the surface of the seed that is applied to paddy rice, wheat, corn or jowar, mix and stir to the surface of the seed moisture state; Or above-mentioned dilution is sprayed on the leaf, stem, fringe of cereal crops, or on the leaf of vegetable crop, stem, fruit, or on the fruit of fruits, to surface wettability; 5) for improving bactericidal effect, can repeatedly spray.
When the dilution derivative, can also in reactor, add copper nitrate with derivative content equivalent.The optium concentration of described dilution is 50～100PPM;
With the application of derivative as the auxiliary antistaling agent of fruit, its key step comprises with isothiazoline in the present invention:
1) get a kind of different azoles thiophene quinoline ketone derivatives, its active ingredient is:
A: B=3: in 1 formula: A is the different azoles thiophene quinoline of 5-chloro-2-methyl-4--3-ketone
B is that the chemical structural formula of the different azoles thiophene quinoline of 2-methyl-4--3-ketone A is:
The chemical structural formula of B is:
2) adopt enamel reaction still or plastics reactor, and add distilled water, deionized water, underground water or clean tap water; 3) with 1) in isothiazolinone derivatives add in the reactor, and dilution is the dilution of 1～100PPM; 4) above-mentioned dilution sprinkling being applied to fruit surface, is moisture state until its surface.5) subsequently sprinkling there is the fruit of dilution to pack in the fresh-keeping packaging.The best working concentration of described dilution is 75PPM, and its spraying time can be before fruit picking, or behind fruit picking.
The major advantage that isothiazolinone derivatives is compared with agricultural bacteriocide commonly used as crop bactericide is its tasteless, odorless under the condition of using and in the overall process, be degraded to the material of environmental sound after 6 months, be a kind of green bactericide, this will make major contribution to environmental protection.
Isothiazolinone derivatives helps the major advantage of antistaling agent to be that it is sprayed at fruit surface prolongs normal freshness date more than 90 days afterwards as the fruit fear.
Embodiment one:
Adopt 1 cubic metre of enamel reaction still or plastics reactor, add distilled water and add copper nitrate with weight such as derivative content simultaneously, the isothiazolone derivative as microbicide of 1.5% specification is diluted to 200 times dilution (75PPM), sprinkling is applied to rice paddy seed mixes and stirs to moisture state, and perhaps the seed of wheat, corn, jowar mixes and stirs moisture state.Can prevent and treat bakanae disease of rice, control efficiency is at 90%-100%.Can prevent and treat the smut of wheat, corn, jowar, control efficiency is at 90-100%.
In embodiment one, copper nitrate is decided agent as fringe and is added, and medicament is in time used and can also do not added,
Embodiment two:
The dilution (75PPM) identical with embodiment one sprays the leaf that is applied to grape, stem, fringe (bud), fruit to moisture state, can prevent and treat grape cob disease, downy mildew, white rot, and control efficiency is 90% to 100%.The application times frequency, then control efficiency is good.
Embodiment three:
The dilution (75PPM) identical with embodiment one sprays the leaf, stem, the fringe that are applied to paddy rice, can prevent and treat bacterial blight of rice, rice blast, false smut, and control efficiency is 90% to 100%.
Embodiment four:
The dilution (75PPM) identical with embodiment one sprays the leaf that is applied to eggplant, stem, root, really, can prevent and treat eggplant verticillium wilt; Be sprayed on leaf, stem, the root of asparagus, can prevent and treat the asparagus stem wilt; Control efficiency is at 90-100%.
Embodiment five:
The dilution identical with embodiment one sprays thin dishes such as being applied to Chinese cabbage, can prevent and treat diseases such as soft rot, downy mildew, and control efficiency is at 95-100%.
Embodiment six:
The dilution (75PPM) identical with embodiment one sprays the leaf that is applied to watermelon and cucumber, stem, really, can prevent and treat watermelon blight, and control efficiency 80%-100% can cucumber blight disease, control efficiency 90-100%.
The present invention also comprises following content, banana, citrus, apple, grape and eggplant, fresh kidney beans, garlic platform etc. pluck adopt preceding or pluck after spray isothiazolinone derivatives dilution (75PPM) immediately and can prevent and treat anthracnose, diseases such as blossom-end rot, fresh-keeping effect is obvious, can make freshness date prolong more than 90 days under refrigerated condition.
Embodiment seven:
The dilution (75PPM) identical with embodiment one sprays and is applied to citrus or apple or banana tree crown, makes leaf, stem, branch, wooden fork and really to moisture state, can prevent and treat anthracnose, blossom-end rot, control efficiency 80-100%.
Embodiment eight:
Kyoto grape sprays isothiazolinone derivatives solution (75PPM) one time before adopting plucking, and then plucks and puts into the thin bag of plastics, with low case packing, under refrigerated condition, puts into the antistaling agent sheet routinely, can prolong fresh keeping time more than 90 days.
The experiment proved that the concentration of the isothiazolone derivative dilution in embodiment one-eight is changed into 1-5PPM by 75PPM, produces and repeat to spray 2-5 time, its effect is identical.
Before the moon, do not find that as yet the isothiazolinone derivatives bactericide produces poisoning to crops.
Claims (6)
1, a kind of isothiazolinone derivatives is as the application of crop bactericide, and its key step is: 1) get a kind of isothiazolinone derivatives, its active ingredient is:
A: B=3: in 1 formula: A is 5-chloro-2-methyl-4-isothiazoline-3-ketone
B is that the chemical structural formula of 2-methyl-4-isothiazoline-3-ketone A is:
The chemical structural formula of B is:
2) adopt enamel reaction still or plastics reactor, and add distilled water, deionized water, underground water or clean tap water; 3) with 1) in isothiazolinone derivatives add in the reactor, and dilution is the dilution of 1～300PPM; 4) above-mentioned dilution is sprayed the surface of the seed that is applied to paddy rice, wheat, corn or jowar, mix and stir to the surface of the seed moisture state; Or above-mentioned dilution is sprayed on the leaf, stem, fringe of cereal crops, or on the leaf of vegetable crop, stem, fruit, or on the fruit of fruits, to surface wettability; 5) for improving bactericidal effect, can repeatedly spray.
2, application as claimed in claim 1 is characterized in that can adding the copper nitrate with derivative content equivalent in reactor.
3, application as claimed in claim 1, the best working concentration that it is characterized in that described dilution is 50～100PPM;
4, a kind of isothiazolinone derivatives is as the auxiliary fresh-keeping application of fruit, and its key step comprises: 1) get a kind of isothiazolinone derivatives, its active ingredient is:
A: B=3: in 1 formula: A is 5-chloro-2-methyl-4-isothiazoline-3-ketone
B is that the chemical structural formula of 2-methyl-4-isothiazoline-3-ketone A is:
The chemical structural formula of B is:
2) adopt enamel reaction still or plastics reactor, and add distilled water, deionized water, underground water or clean tap water; 3) with 1) in isothiazolinone derivatives add in the reactor, and dilution is the dilution of 1～100PPM; 4) above-mentioned dilution sprinkling being applied to fruit surface, is moisture state until its surface.5) subsequently sprinkling there is the fruit of dilution to pack in the fresh-keeping packaging.
5, application as claimed in claim 4 is characterized in that the best use value of described diluted concentration is 75PPM.
6, application as claimed in claim 4, the time that it is characterized in that spraying dilution is before fruit picking, or behind fruit picking.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99106088 CN1236542A (en) | 1999-05-04 | 1999-05-04 | Application of isothiazolinone derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99106088 CN1236542A (en) | 1999-05-04 | 1999-05-04 | Application of isothiazolinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1236542A true CN1236542A (en) | 1999-12-01 |
Family
ID=5272254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 99106088 Pending CN1236542A (en) | 1999-05-04 | 1999-05-04 | Application of isothiazolinone derivatives |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1236542A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530100A (en) * | 2009-04-27 | 2009-09-16 | 陕西上格之路生物科学有限公司 | Isothiazolone agricultural bactericide |
| CN100560661C (en) * | 2003-06-11 | 2009-11-18 | 科莱恩产品（德国）有限公司 | The aqueous colorant preparations of stabilization |
| CN103583544A (en) * | 2013-11-26 | 2014-02-19 | 中国农业科学院植物保护研究所 | Application of 1% isothiazolinone.2% methylene bisthiocyanate missible oil in prevention and treatment of bacterial fruit blotch, and 1% isothiazolinone.2% methylene bisthiocyanate missible oil |
| CN103749514A (en) * | 2014-01-23 | 2014-04-30 | 中国农业科学院植物保护研究所 | Application of 1% isothiazolinone/2% methylene bisthiocyanate emulsifiable concentrate in controlling triploid watermelon fruit blotch |
-
1999
- 1999-05-04 CN CN 99106088 patent/CN1236542A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100560661C (en) * | 2003-06-11 | 2009-11-18 | 科莱恩产品（德国）有限公司 | The aqueous colorant preparations of stabilization |
| CN101530100A (en) * | 2009-04-27 | 2009-09-16 | 陕西上格之路生物科学有限公司 | Isothiazolone agricultural bactericide |
| CN103583544A (en) * | 2013-11-26 | 2014-02-19 | 中国农业科学院植物保护研究所 | Application of 1% isothiazolinone.2% methylene bisthiocyanate missible oil in prevention and treatment of bacterial fruit blotch, and 1% isothiazolinone.2% methylene bisthiocyanate missible oil |
| CN103749514A (en) * | 2014-01-23 | 2014-04-30 | 中国农业科学院植物保护研究所 | Application of 1% isothiazolinone/2% methylene bisthiocyanate emulsifiable concentrate in controlling triploid watermelon fruit blotch |
| CN103749514B (en) * | 2014-01-23 | 2015-08-12 | 中国农业科学院植物保护研究所 | The application of 1% isothiazolinone 2% 2 sulphur cyanogen methane missible oil in control triploid watermelon fruit blotch |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Riseh et al. | Chitosan-based nanocomposites as coatings and packaging materials for the postharvest improvement of agricultural product: A review | |
| US20230165248A1 (en) | Antimicrobial Compositions and Related Methods of Use | |
| Meng et al. | Physiological responses and quality attributes of table grape fruit to chitosan preharvest spray and postharvest coating during storage | |
| Romanazzi et al. | Combination of chitosan and ethanol to control postharvest gray mold of table grapes | |
| US20240180155A1 (en) | Antimicrobial Compositions and Related Methods of Use | |
| Czajkowski et al. | Chemical disinfectants can reduce potato blackleg caused by ‘Dickeya solani’ | |
| US20090018194A1 (en) | Use of antimicrobial agents derived from alliaceous plants for the prevention and control of crop diseases, post-harvest rot and as environmental disinifectant products | |
| CN1236542A (en) | Application of isothiazolinone derivatives | |
| Ali et al. | Application of ROS, RNS, and RSS for prolonging the shelf-life of horticultural crops via the control of postharvest bacterial infections | |
| Schena et al. | Biocontrol activity of bio-coat and biocure against postharvest rots of table grapes and sweet cherries | |
| WO2002069708A1 (en) | Glycerine as fungicide or bactericide active substance | |
| Kassem et al. | Comparative Efficacy of Chemical Salts and Fungicides for Controlling Date Fruit Rots | |
| Kuchi et al. | Commercial Disinfectants in Skirmishing Postharvest Diseases | |
| Enríquez-Castro et al. | Innovation in food products using ozone technology: Impact on quality assurance | |
| US20220304302A1 (en) | Mucilage based plant protection product and method thereof | |
| US20230172199A1 (en) | Antimicrobial Compositions and Related Methods of Use | |
| Trapman | Evaluation of grapefruit seed extract as natural fungicide to control apple scab in organic apple growing | |
| Savage | Further optimisation of in-line aqueous application of imazalil to control citrus green mould caused by Penicillium digitatum | |
| Tebbets | CALIFORNIA APPLE COMMISSION RESEARCH SUMMARY | |
| DeGenring et al. | Postharvest chitosan sprays reduce bitter rot and blue mold on apple fruit | |
| EP1937067B1 (en) | Use of an agent for stimulating the defense system of plants and production thereof | |
| WO2024123192A1 (en) | Formulations and methods of use | |
| Vero et al. | Integrated approaches to postharvest biocontrol | |
| Ligorio et al. | Pre-and postharvest application of salts for controlling green and blue mould of Clementine. | |
| Fulerton | Preharvest sanitisers and fungicides for reducing Penicillium digitatum inoculum on cv Satsuma mandarin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |