CN1226962C - Cervical tissue sampling device - Google Patents

Cervical tissue sampling device Download PDF

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Publication number
CN1226962C
CN1226962C CN 95197765 CN95197765A CN1226962C CN 1226962 C CN1226962 C CN 1226962C CN 95197765 CN95197765 CN 95197765 CN 95197765 A CN95197765 A CN 95197765A CN 1226962 C CN1226962 C CN 1226962C
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China
Prior art keywords
sampling device
tissue sampling
piston
cervical tissue
cylinder
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Expired - Fee Related
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CN 95197765
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Chinese (zh)
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CN1177917A (en
Inventor
W·G·沃森
霍华德·V·沃森
W·J·邓恩
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Gynetech Inc
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Gynetech Inc
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Priority to CN 95197765 priority Critical patent/CN1226962C/en
Publication of CN1177917A publication Critical patent/CN1177917A/en
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Publication of CN1226962C publication Critical patent/CN1226962C/en
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Abstract

The present invention relates to a cervical tissue sampling device (10). A woman uses the cervical tissue sampling device to collect a tissue sample at home, and thereby, the tissue sample is posted, or sent to a test room in other modes. The cervical tissue sampling device comprises a cylinder (12). The cylinder is provided with a circular opening front end (14) and a circular opening rear end. The circular opening rear end is ended in the position of a finger-shaped clamping flange (16) which is extended in a radial direction and has an irregular shape. A slip piston device (33) positioned in the cylinder (12) comprises an annular brush (34) and a circumambient annular spongy body (40) for collecting cervical tissues and mucus. Collection devices of the annular brush (34) and the circumambient annular spongy body (40) can be installed onto a rod of a piston (33) in a dismountable mode by quick releasing connections (52, 54, 56, 58, 60, 62). When the cervical tissue sampling device is used, the cylinder (12) in which the circumambient annular spongy body (40) and the annular brush (34) are arranged is inserted into a vagina (V) by a woman, and the cylinder (12) is in a contraction state. After the cervical tissue sampling device is inserted into the vagina (V), the piston (33) is moved to be in an expansion state and to rotate, and thereby, a tissue sample and a mucus sample are collected from the annular brush (34) and the circumambient annular spongy body (40). After the tissue sample and the mucus sample are collected, the circumambient annular spongy body (40) and the annular brush (34) are disassembled from the rod of the piston. The tissue sample and the mucus sample are posted to a test room through a sealed container to be analyzed.

Description

Cervical tissue sampling device
Technical field
The invention provides a kind of cervical tissue sampling device, it makes the Ms obtain the sample of survival in the private room in the own home, comprises that cell tissue intrauterine, cervix uteri and vagina is for the control laboratory inspection.
Background technology
The microscopy of cervical tissue and mucus sampling section is proved to be to reduce the effective method of women's uterus carcinoma mortality rate.American Cancer Society thinks that the women does one time the mucus plate coating checking at least every year.But unfortunately, many women do not participate in annual microscopy because of a variety of causes, comprise the infringement of audit program to individual privacy, go to see the gynaecologist need high cost, do not believe the accuracy of inspection, because of work or other movable examination in hospital etc. of having no time.Studies show that the annual microscopy that carries out effectively can make the M ﹠ M of uterus carcinoma reduce 90%.
Summary of the invention
In order to cause the concern of each side, the invention provides a kind of cervical tissue sampling device, it makes the Ms obtain the sample of survival in the private room in the own home, comprises that cell tissue intrauterine, cervix uteri and vagina is for the control laboratory inspection.Cervical tissue sampling device of the present invention can make women's collection organization's sample of staying at home, and by the mailing or other modes deliver to control laboratory, this device comprises a cylinder, this cylinder has a circular open front end and a circular open rear end, its fingers in irregular shape that ends at radially expansion blue place of enforcing the law.The slidably piston apparatus that is positioned at cylinder comprise an annular brush and around the annular sponge body, to collect cervical tissue and mucus.Connect by rapid release, brush and spongy body gathering-device are releasably attached on the piston rod.In use, by the Ms cylinder that has spongy body and brush in it and be contraction state is inserted its vagina, after the insertion, piston is moved to extended configuration and rotates, thus on brush and spongy body collection organization and mucus sample.Collected after the sample, pulled down spongy body and brush, and posted to control laboratory analysis with a sealed container from piston rod.
The invention provides a kind of cervical tissue sampling device, it comprises: cylinder; Be arranged on the piston sliding back and forth in the cylinder; Be fixed on the gathering-device that is used for collection organization of piston end; Gathering-device comprises a brush and a spongy body, and the chosen size of this spongy body also is configured to when piston retraction is in the cylinder, and brush is also protected in the spongy body sealing; Connecting device, it is fixed to gathering-device on the piston in separable mode.Cervical tissue sampling device of the present invention can make women's collection organization's sample of staying at home, and delivers to control laboratory by mailing or other modes, and is fairly simple, convenient.
Description of drawings
But in order to understand the present invention better, advantage of the present invention and use the purpose that the present invention reached, should be further with reference to as this description another part and show the accompanying drawing of most preferred embodiment.In the accompanying drawing:
Fig. 1 represents that integral body is in the front perspective view of the cervical tissue sampling device of the present invention of contraction state.
Fig. 2 represents that integral body is in the rear view of the cervical tissue sampling device of the present invention of contraction state.
Fig. 3 represents the rear view of the piston apparatus of cervical tissue sampling device of the present invention.
Fig. 4 represents to be in the front view of the cervical tissue sampling device of the present invention of contraction state.
Fig. 5 represents the rearview of cervical tissue sampling device of the present invention.
Fig. 6 represents to be in the side view of the cervical tissue sampling device of the present invention of contraction state.
Fig. 7 represents to be in the plane graph of the cervical tissue sampling device of the present invention of contraction state.
Fig. 8 represents the partial, exploded perspective view of cervical tissue sampling device of the present invention.
Fig. 9 represents to be in the rear view of the cervical tissue sampling device of the present invention of extended configuration.
Figure 10 represents the sketch map of cervical tissue sampling device using method of the present invention.
The specific embodiment
Please refer to accompanying drawing (wherein identical Reference numeral is represented identical structure in these figure) now, particularly with reference to Fig. 1, Fig. 2 and Fig. 8.According to a first advantageous embodiment of the invention, cervical tissue sampling device 10 comprise one elongated, basically inflexible cylinder 12, this cylinder 12 has circular open front end 14 and is positioned at the circular open rear end 28 of circular trough 29, and this circular trough 29 is in the fingers of an out-of-shape and radially extension is enforced the law orchid 16.Preferably by being positioned at U.S. Sapulpa, #PE 2067 low density polyethylene (LDPE)s that the Branchcomb industrial group of Oklahoma produces are made for cylinder 12 and flange 16.As Fig. 4, Fig. 5 and shown in Figure 8, fingers is enforced the law and blue 16 is had the angle lobe 20,22,24 and 26 of protruding arc curve around being of flange 16.These angle lobe separate by being recessed arcual recess 21,23,25 and 27 respectively.Can see with reference to Fig. 2, cylinder 12 is Unitarily molded molding with flange 16, or also can assemble by the parts that separate, promptly packed in the circular hole of flange 16 intermediate formation in the circular open rear end 28 of cylinder 12, also can use suitable binding agent that flange 16 is fastened on the cylinder 12 by extruding.As shown in Figure 8, cylinder 12 side within it distributes vertically and has the interior ridge 30 and 32 of certain intervals by flange 16 1 ends, so that piston apparatus remains on wherein, will be illustrated in more detail below.
With reference to Fig. 3 and Fig. 8, cervical tissue sampling device 10 comprises piston apparatus 33 according to the present invention, the end of piston apparatus 33 finishes with an annular brush 34, annular brush 34 residing planes are vertical substantially with the longitudinal axis of piston apparatus 33, and annular brush 34 is preferably made by 36 windings of stainless steel silk nylon mane.Suitable brush is to be made by the nylon of 0.005 inch of 304 stainless steel silks of 0.02 inch of specification standards MS 209956, diameter and FDA#21CFR177-1500,612 natural fiber nylon, diameter, and it is produced by California State, USA Los Angeles city Gordon Brush company.Initial straight brush became illustrated annular brush afterwards, and it has the stem 38 of a stainless steel silk 36 that extends back by the centre bore of annular sponge body 40.Suitable spongy body is that a diameter is 2 inches a annulus, and its thickness is 0.0625 inch, #1935 opening cellulose sponge, and the middle hole that has 0.25 inch, and it is that Lundell manufacturing company by the Minnesota ,USA continent produces.About 3.5 centimetres of annular brush 34 diameters, and around the diameter of spongy body 40 be about 5.0 centimetres.In general the cervix uteri diameter is 5.0~5.5 centimetres.The stem 38 of stainless steel silk 36 is pressed into cylinder 44 in the centre bore 46 at rounded termination flange 42 places that radially expand.Cylinder 44 is inserted in the sleeve 50, and sleeve ends at the radially second rounded termination flange, 48 places of expansion.The back of 42 pairs of spongy bodies of terminal flange has formed a linkage interface, and is used for spongy body 40 is pressed on the back of annular brush 34.Flange 42 because have one than the big external diameter of flange 48 and sleeve 50 internal diameters also as the baffle plate that stops sleeve 50 to move forward vertically.Cylinder ends at vertically semicylinder union joint 52 places that form to inner face.Alignment pin 54 extends transverse to the axis of cylinder 44 from the inner side plane center of union joint 52.Second sleeve, the 56 chosen sizes that have a rounded termination flange 58 of radial expansion make its can be relative with cylinder 44 and piston 64 closely with slidably, the mode that has an internal friction resistance cooperates.As shown in Figure 8, piston rod 64 stops at the second semicylinder union joint, 60 places that have horizontal expansion jack 62 of friction engagement with the alignment pin 54 of cylinder 44 union joints 52 mutually being used for.Therefore, also can be regarded as cylinder 44 and piston rod 64 is connected for alternative separate type.Like this, come out up to union joint 52 and 60 by slide backward sleeve 56 along piston rod 64, the brush 34 and the spongy body 40 of cylinder 44 and attaching just can be dismantled arbitrarily.Follow available hands alignment pin 54 is removed from jack 62, thereby cylinder 44 is separated with piston rod 64.
Piston rod 64 is to be mutually 90 bars 66,68,70 and 72 of spending extension vertically by 4 to constitute.Crossbar 74,76,78 and 80 centers by piston rod 64 constitute one and support cross to external radiation, be used to keep piston rod 64 integral body to be in the center of cylinder 12 substantially.The interior ridge 30 and 32 (Fig. 8) that supports 12 li of cross and cylinders matches in the ratchet mode, thereby prevents piston apparatus 33 undesigned stretching, extension or contractions.The rear end of piston rod 64 ends at the part 82,84,86 and 88 places of radially expansion, they and plunger 90 integrated poured forming.Axially extended handle 92 crosses out from the outer end face of plunger 90, thereby offers the surface of a grasping of user, makes the user can be with respect to cylinder 12 stretching, extensions, contraction and rotating piston device 33.Each element of piston apparatus 33 preferably all is by being positioned at U.S. Oklahoma, and the #PP14B12A co-polymer polypropylene that the geographic Branchcomb of Sapulpa industrial group produces is made.
According to cervical tissue sampling device using method of the present invention be: a Ms keeps sweptback posture as shown in figure 10, and cylinder 12 is inserted vagina V.It should be noted that the local on position of the cylinder 12 that in Figure 10, only shows cervical tissue sampling device 10.In fact, cylinder 12 is further inserted, and the open front 14 of cylinder 12 and the surface of cervix C is contacted, thereby exert pressure gently to the surface of cervix C.At this moment, the opening of cervix C contacts vertically fully with cylinder 12, and as described below when piston apparatus 33 is stretched, the mane of brush 34 just enters the opening of cervix uteri, to obtain to analyze the intrauterine cell of usefulness.
When piston apparatus 33 was in contraction state illustrated in figures 1 and 2, the support cross that is made of crossbar 74,76,78 and 80 was placed between the interior ridge 30 and 32 (Fig. 8).In this case, spongy body 40 is in contraction state in cylinder 12, shown in Fig. 1,2,4,6,7.At this moment, spongy body 40 is in the cylinder of cylinder 12 substantially so that insert.Insert after the cylinder 12, by means of fingers enforce the law blue 16, plunger and handle 92, Ms's extend piston device 33.Owing to make the elasticity of the plastic material of crossbar 74,76,78 and 80, the stretching, extension of piston apparatus 33 can cause supporting cross and cross the interior ridge 32 and the (see figure 8) that is stuck.At this moment, plunger 90 is placed in groove 29 (see figure 2)s that are positioned at flange 16, thereby has limited the further stretching, extension of piston apparatus 33.Groove 29 has formed the axle journal bearing-surface of a rotation fixed cylinder plug 90, and piston rod 64 is fixed in the axial centre position, so that sampling.At this moment, as shown in Figure 9, spongy body 40 bounces back into opening-wide state because of its natural elasticity, and exposes annular brush 34 shown in Figure 8.Then, the user brush 34 being convenient to expose for rotation piston device 33 by handle 92 people and spongy body 40 are collected tissue and mucus sample on intrauterine, cervix uteri and the vaginal wall from vagina V and cervix C.
Finish after the sampling, the contraction haptic signal that sent of ridge 32 in crossing by means of the support cross that blocks, the Ms shrinks the position that piston apparatus 33 begins to it, makes that sample collected is protected in cylinder 12 on brush 34 and the spongy body 40.Then, user is by clamping flange 16 withdrawing devices 10, in cylinder 12, take out piston apparatus 33, and utilize shown in Figure 8 by union joint 52 and 60 formed detachable connections, the outer end of isolation piston device 33 (comprising brush 34 and spongy body 40) vertically.
Should be noted that spongy body 40 not only has the effect of collecting sample, and have the function of protection brush 34 and sample.When piston apparatus 33 was retracted, spongy body 40 closes up got back to its position as depicted in figs. 1 and 2, thereby spongy body 40 will seal and protect brush and sample.
Sampler 10 can completely be sold, and comprises the suitable lubricant of being convenient to insert, and sealable small container, and with the separable outer end of piston apparatus 33, promptly control laboratory analysis is posted or delivered to spongy body 40 and brush 34.
Device 10 is very cheap, and easy to use, and therefore, the Ms can use this device collection analysis tissue sample in the private room in the own home.
Yet must be clear, although numerous characteristics of the present invention and advantage are narrated in front together with detailed structure of the present invention and function, but this announcement also only is a kind of explanation, many thin portions structure can be done modification, particularly may have some at the aspects such as assembling of material, shape, size and parts and change, these variations all should be summarised in appending claims and extend the deadline most within the fixed principle of the present invention.

Claims (20)

1. cervical tissue sampling device (10) comprising:
Cylinder (12);
Be arranged on the piston sliding back and forth (33) in the above-mentioned cylinder (12);
Be fixed on the terminal gathering-device that is used for collection organization (34,40) of described piston (33);
Described gathering-device (34,40) comprises a brush (34) and a spongy body (40), the chosen size of this spongy body and when being configured in described piston (33) is retracted to cylinder (12), and described brush (34) is also protected in described spongy body sealing;
Connecting device, it is fixed to described gathering-device (34,40) on the described piston (33) in separable mode.
2. cervical tissue sampling device as claimed in claim 1 (10) is characterized in that, described brush (34) is annular.
3. cervical tissue sampling device as claimed in claim 2 (10) is characterized in that, annular brush (34) residing plane is vertical with the longitudinal axis of described piston (33).
4. cervical tissue sampling device as claimed in claim 2 (10) is characterized in that, described spongy body (40) is annular.
5. cervical tissue sampling device as claimed in claim 4 (10) is characterized in that, when extended configuration, the residing plane of annular sponge body (40) is vertical with the longitudinal axis of described piston (33).
6. cervical tissue sampling device as claimed in claim 1 (10) is characterized in that described connecting device comprises interlock, i.e. first union joint (52) and second union joint (60).
7. cervical tissue sampling device as claimed in claim 6 (10) is characterized in that, described first union joint (52) and second union joint (60) all are semi-cylindrical.
8. cervical tissue sampling device as claimed in claim 7 (10) is characterized in that, first union joint (52) comprises located lateral pin (54), and second union joint (60) comprises the horizontal jack (62) that matches.
9. cervical tissue sampling device as claimed in claim 1 (10), it is characterized in that, described sampler also comprises pawl device (30,32,74,76,78,80), described pawl device prevents unintentionally stretching, extension or the contraction of above-mentioned piston (33) with respect to described cylinder, and provides haptic signal to user when piston (33) shrinks.
10. cervical tissue sampling device as claimed in claim 9 (10) is characterized in that, the pawl device (30 that forms in described cylinder (12), 32,74,76,78,80) comprise two interior ridges (30 that have certain intervals vertically, 32), with the crossbar that extends radially outward (74,76 on this piston (33), 78,80) match.
11. cervical tissue sampling device as claimed in claim 1 (10) is characterized in that, described sampler also is included in extended configuration and is used for fixing the supporting arrangement (29,90) that described piston (33) makes it rotate at cylinder (12) center.
12. cervical tissue sampling device as claimed in claim 11 (10), it is characterized in that, described supporting arrangement comprise on the piston (33) plunger (90) and near the formed auxiliary flute of abutting end (29) of cylinder (12), when being in extended configuration, this auxiliary flute (29) part receives described plunger (90) at described piston (33).
13. cervical tissue sampling device as claimed in claim 12 (10) is characterized in that, described groove (29) is located at the formed fingers of abutting end near cylinder (12) and enforces the law in the orchid (16).
14. cervical tissue sampling device as claimed in claim 1 (10) is characterized in that,
Rubber-like approaches spongy body (40) and is arranged near described piston (33) end, and when piston (33) when being in extended configuration, the residing plane of described spongy body (40) is vertical with the longitudinal axis of described piston (33);
Brush (34) is fixed in piston (33).
15. cervical tissue sampling device as claimed in claim 10 (10) is characterized in that, described device further is included in extended configuration and is used for fixing described piston (33) rotates it substantially at cylinder (12) center supporting arrangement.
16. cervical tissue sampling device as claimed in claim 15 (10), it is characterized in that, described supporting arrangement comprise on the piston (33) plunger (90) and near the formed auxiliary flute of abutting end (29) of cylinder (12), when being in extended configuration, this auxiliary flute (29) to small part receives described plunger (90) at described piston (33).
17. cervical tissue sampling device as claimed in claim 16 (10) is characterized in that, described groove (29) is located at the formed fingers of abutting end near cylinder (12) and enforces the law in the orchid (16).
18. cervical tissue sampling device as claimed in claim 10 (10) is characterized in that,
Described connecting device comprises that one has first union joint (52) of located lateral pin (54) and has second union joint (60) of the horizontal jack (62) that matches; One sleeve, the chosen size of this sleeve can with described first union joint (52) and second union joint (60) frictional fit, so that described gathering-device (34,40) is fixed on the described piston (33).
19. cervical tissue sampling device as claimed in claim 18 (10) is characterized in that, described first union joint (52) and second union joint (60) all have an inside plane surface that joins.
20. cervical tissue sampling device as claimed in claim 19 (10) is characterized in that, described groove (29) is located at the formed fingers of abutting end near cylinder (12) and enforces the law in the orchid (16).
CN 95197765 1995-01-17 1995-01-17 Cervical tissue sampling device Expired - Fee Related CN1226962C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 95197765 CN1226962C (en) 1995-01-17 1995-01-17 Cervical tissue sampling device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 95197765 CN1226962C (en) 1995-01-17 1995-01-17 Cervical tissue sampling device

Publications (2)

Publication Number Publication Date
CN1177917A CN1177917A (en) 1998-04-01
CN1226962C true CN1226962C (en) 2005-11-16

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Application Number Title Priority Date Filing Date
CN 95197765 Expired - Fee Related CN1226962C (en) 1995-01-17 1995-01-17 Cervical tissue sampling device

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100348145C (en) * 2004-09-07 2007-11-14 陶襄萍 Integrated separable diagnostic endoscope for vagina and anus
NL2003379C2 (en) * 2009-08-21 2011-02-23 Rovers Holding B V SAMPLING DEVICE AND METHOD FOR PREPARING THEM.
EP2925234B1 (en) * 2012-11-30 2017-08-16 Eve Medical Inc. Specimen collection device and kit
KR101865555B1 (en) * 2013-10-14 2018-06-08 디엔에이 리서치 센터 (엠) 에스디엔 비에이치디 Exocervical and endocervical cell sampling device
TR201800276A2 (en) * 2018-01-09 2018-02-21 Alravvi Omar HVS AND PAP SQUARE TEST APPARATUS
CN109998600A (en) * 2019-04-25 2019-07-12 大连大学 A kind of ox rectum is adopted civilian dress and is set

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Granted publication date: 20051116

Termination date: 20100219