CN1225024A - Flexible piston rod - Google Patents

Flexible piston rod Download PDF

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Publication number
CN1225024A
CN1225024A CN 97196192 CN97196192A CN1225024A CN 1225024 A CN1225024 A CN 1225024A CN 97196192 CN97196192 CN 97196192 CN 97196192 A CN97196192 A CN 97196192A CN 1225024 A CN1225024 A CN 1225024A
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CN
China
Prior art keywords
piston rod
support
band
ampoule
sheet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 97196192
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Chinese (zh)
Inventor
彼得·克里斯蒂安·科利特戈尔德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
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Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Priority to CN 97196192 priority Critical patent/CN1225024A/en
Publication of CN1225024A publication Critical patent/CN1225024A/en
Pending legal-status Critical Current

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Abstract

A flexible piston rod for use in cylinder ampoules comprises a tape shaped body (1) which is along its length provided with supporters (2, 6, 16) projecting from at least one side of the tape. The tape (1) has a width and the supporters have a length so that sides of the tape and the free ends of the supporters abut the inner wall of the ampoule (3) in at least three positions along the inner perimeter of the ampoule (3) and not all the abutment points lie on the same half of the circular cross section but are typically displaced about 120 DEG from each other. The piston rod is moved by a gear engaging a rack (12) on the tape either on the side not carrying supporters or at the edge of the tape on the side carrying supporters.

Description

Flexible piston rod
The present invention relates to a kind of flexible piston rod of syringe.
Syringe generally is equipped with rigid piston rod, and it is pushed into the other end to piston from an end of needle tubing, by the syringe needle that is installed in this other end the content of needle tubing is extruded.The length of this syringe generally is the twice of needle tubing length at least.
In order to shorten the length of syringe, flexible piston rod has been proposed, this piston rod can deflection, thus its exposed parts is parallel to needle tubing, in abutting connection with needle tubing and do not extend on the axis of needle tubing.
WO95/09021 has described a kind of flexible piston rod that has the syringe of needle tubing support and dose setting device.Set dosage and extruded needle tubing by flexible piston rod, this flexible piston rod is installed in 180 ° of the piston rod guider deflections at next-door neighbour needle tubing rear, this syringe is following pattern: after piston rod is extracted out from the empty needle pipe, this empty needle pipe can be replaced by new needle tubing, so the piston rod guider must be designed to following pattern: transmitting at piston rod all can the support piston bar under pressure and two kinds of situations of pulling force.Above-mentioned requirements can realize by the piston rod guider that uses the curved tube shape, and this piston rod guiding means supports is made into all faces of piston rod of the steel spring of compact winding.
When being used to have the disposable syringe of flexible piston rod, the piston rod guider is support piston bar when the piston of piston rod in needle tubing transmits pressure only, therefore can use simpler piston rod guider.And then, wish to use and to make the disposable syringe identical materials, promptly plastics are made piston rod, have reduced recuperability because metal parts and plastic part mixed.Simultaneously, piston rod is compromise between need and wishing in following requirement: both required piston rod enough rigidity to be arranged and unlikely bending, and wished the material of consumes least again.
Learn from EP110687: use flexibility to push away the band driven plunger and enter needle tubing, this band is formed by the plastics manufacturing of for example molded polypropylene, and required rigidity is with the protruding part of side to obtain by the cross section of this band bending and along this.The curved shape of cross section is crooked corresponding with needle interior wall, thereby this band is all being contacted with needle interior wall in the width range.
Yet, when the band with crooked cross section was deflected circular arc, this band certainly will present linear cross section, in addition, when the part of being discussed no longer was circular arc, the memory characteristic that plastics had made and keeps linear cross section can not obtain the initial bending shape automatically in a period of time.Therefore, attempt with the corresponding to cross section of needle interior wall curved shape be insecure.
The objective of the invention is to propose a kind of made of plastic can be outside needle tubing the flexible piston rod of deflection, it is used to promote piston and enters needle tubing and do not bend in needle tubing.
Above-mentioned purpose can realize by a kind of piston rod, this piston rod is made up of a band body, length direction along the band body is equipped with support, these support at least and stretch out from one side of band, this band has certain width, supports to have certain-length, therefore along the inner periphery of ampoule, the side of band and the end of support contact three positions at least with the ampoule inwall, and all strong points do not drop in the same semicircle of circular cross section entirely.
Embodiment according to a piston rod of the present invention, the length of the string of the about 120 ° of arcs of leap is suitable on the interior cross section of the width of its band body and ampoule circle, support along the direction towards one side of the axis of ampoule perpendicular to band and protrude, the contact point of it and ampoule inwall becomes about hexagonal angle with the two sides of being with body respectively.
According to the present invention, can at regular intervalsly make piston rod between the support to one side deflection that support is housed.Can support be set to be increased in the rigidity of the piston rod in the ampoule on the both sides of band, for this piston rod, the piston rod guider must be provided with groove to hold the support of stretching out on the moving direction of piston rod.
In addition, as selection, each supports the placement that can adjoin each other, thereby piston rod can only be to one side deflection away from support, and the piston rod guider must be provided with groove to hold the support of stretching out.
According to the embodiment of a piston rod of the present invention, be plate shape in vertical upper support of piston rod, it perpendicular to the piston body of rod and by piston rod vertically on the connector of little length be connected with the piston body of rod.This structure has enhanced rigidity and since plate and piston rod to be connected length little, for example the thickness with the band that forms piston rod has same order, therefore can not reduce the flexibility of piston rod on bar vertical.
According to the embodiment of another piston rod of the present invention, bar is made up of band shape sheet, and each sheet is equipped with a plate shape along whole length and supports, and this sheet is connected by hinge makes sheet one side deflection that supports is not installed to.In this embodiment, obtain on the basis of overall flexibility the rigidity that the band shape sheet of formation piston rod obtains at piston rod.
According to the present invention, for the motion of piston rod, both can tooth bar be installed on one side that support is not housed, can be close to support along the side of piston rod on one side identical again tooth bar is installed with support.In the embodiment that hard strap is arranged, tooth bar can be by forming with the sector rack of driving pinion engagement.
The present invention will understand more in detail with reference to following explanation and diagrammatic sketch.
Fig. 1 be one according to insertion ampoule of the present invention and by the side view of the piston rod embodiment of piston rod guider institute deflection.
Fig. 2 is along the cutaway view of line II-II among Fig. 1.
Fig. 3 is another embodiment according to deflection piston rod of the present invention.
Fig. 4 remains the embodiment of another one according to deflection piston rod of the present invention.
Fig. 5 is a further embodiment according to piston rod of the present invention.
Fig. 6 remains a further example according to piston rod of the present invention.
As shown in Figure 1, one side along band shape piston rod 1 spaced apart supports 2 is housed, shown in piston rod insert ampoule 3 and be connected with piston 4 in the above-mentioned ampoule.Piston rod one goes out ampoule promptly by 5 deflections of piston rod guider, and piston rod guider 5 has curved surface, is supporting the convex surface of deflection piston rod.On the limit of piston rod guider 5, the curved surface that is parallel to the piston rod guider is equipped with a plurality of flanges 5 ', spacing between the flange is suitable with the thickness of the band that forms piston rod, each is equipped with another flange 5 above the flange 5 ' "; so just form a guide slide, make piston rod when not being stressed, avoid directly extending along the string of curved surface.Figure 2 shows that the side of band shape piston rod 1 and the end and the situation that circle in the ampoule contacts of support, be with the shape piston rod to contact and make the rectangular cross section of band on the circular cross section of ampoule, form a string with circle in the ampoule.Be supported on perpendicular to the direction towards the one side in the ampoule circular cross section center of circle of band and protrude, in case leukorrhagia stopping bends on this direction.Can lean on following principle to avoid along the direction bending that deviates from the circular cross section center of circle: band must have crooked cross section could allow this bending.When the width hour of band, band has enough rigidity and stops this bending.Yet, for large diameter ampoule, one side be suitable not supporting of band towards being provided with of ampoule cross-section center, support 2 ' as shown in Figure 3.
In example as shown in Figure 1, the piston rod guider makes piston rod towards the direction deflection that supports the place, so just forms a radius of curvature of being determined by the spacing between supporting that deflection allowed.Figure 4 shows that the embodiment of a piston rod, in this embodiment,, support, make the linear piston bar have good rigidity like this in abutting connection with placing when piston rod is linear and not during deflection.If deflection is to stretch out one side of support towards the installation that not have of band shape piston rod, the piston rod guider institute deflection that can not drawn of piston rod so.This piston rod guider must be provided with groove to hold support, and this moment, these supported from being with the face that contacts with the piston rod guider to stretch out.
In embodiment as shown in Figure 1,, has only little stretching, extension in vertical upper support of piston rod if do not hinder the deflection of piston rod.In embodiment as shown in Figure 4, support is a plate body 6, they by piston rod vertically on have only the connector 7 of little stretching, extension to be connected on the piston rod 1.
In embodiment as shown in Figure 5 according to another piston rod of the present invention, band shape piston rod is made up of strap 8, each sheet 8 has vertical wall 9, stretch out perpendicular to one side of piston rod and from this limit, band shape sheet 8 is hinged by hinge 10, thereby forms one just owing to bend and the piston rod of deflection at the hinge place.
Shown in arrow among Fig. 1 11, can exert pressure by the end of the piston rod outside ampoule moves piston rod.In addition, as selection, 12, one of flexible racks can also installing on the band body of piston rod as shown in Figure 4 rotate with the moving of pinion piston rod as requested of this tooth bar engagement, thereby by tooth bar piston rod are moved.Tooth bar both can be installed in one side that support is not installed of piston rod as shown in Figure 4, can be close to support along the side of the band shape piston body of rod again (not showing among the figure) is installed.As selection, can also perforation be set along the piston rod side, the motion of piston rod can obtain by sprocket wheel and above-mentioned perforation engagement.
When piston rod be not overall flexibility but only be that structure between flexible, the hinge is when being inflexible rather than flexible at the hinge place, the tooth bar that is installed in one side that support is not housed can be made the shape of the sector rack of internal-gear, it and outer tooth pinion mesh, thereby promotion piston rod movement, as shown in Figure 6, crooked tooth bar is housed on the rigid disk 13 in this figure on the piston rod, and it and pinion 14 mesh.The another side relative with the tooth bar of bending on piston rod is equipped with sheet shape and supports 16.The deflection of piston rod is obtained by the bending of hinge 15 place's piston rods, and hinge is joined together to form piston rod to rigid disk.

Claims (10)

1. flexible piston rod that is used for the cylinder ampoule, it is characterized in that: piston rod is made up of a band body, length direction along the band body is equipped with support, these support at least and stretch out from one side of band, band has a certain width, supports to have certain-length, therefore along the inner periphery of ampoule, the side of band and the end of support contact three positions at least with the ampoule inwall, and all contact points do not drop in the same semicircle of circular cross section entirely.
2. flexible piston rod as claimed in claim 1, it is characterized in that: the length of string of crossing over about 120 ° of arcs in width and the ampoule circle of band body on the cross section is suitable, with contacting with position that each side of being with body separates about hexagonal angle towards the support of the vertical protrusion in limit of the axis of ampoule and ampoule inwall of band.
3. flexible piston rod as claimed in claim 1 or 2 is characterized in that: the piston rod that makes at regular intervals is to one side deflection that support is housed between the support.
4. flexible piston rod as claimed in claim 1 or 2 is characterized in that: each supports placements that adjoin each other, and makes the piston rod can only be to one side deflection away from support.
5. flexible piston rod as claimed in claim 4 is characterized in that: the vertical upper support at the piston body of rod is plate shape, it perpendicular to the piston body of rod and piston rod vertically on connector by little length be connected with the piston body of rod.
6. flexible piston rod as claimed in claim 4 is characterized in that: piston rod is made up of band shape sheet, and each sheet is equipped with a plate shape along whole length and supports, and this sheet is connected by hinge makes sheet one side deflection that supports is not installed to.
7. as any described flexible piston rod in above-mentioned every claim, it is characterized in that: one side the tooth bar that is provided with of support be not housed.
8. as any described flexible piston rod in above-mentioned every claim, it is characterized in that: one side along the side of the piston body of rod, the tooth bar that is provided with of support is being housed.
9. flexible piston rod as claimed in claim 6 is characterized in that: one side on band shape sheet the segmental tooth bar sheet that is equipped with that supports is not installed, each tooth bar sheet all has certain curvature, so that and pinion.
10. flexible piston rod as claimed in claim 2 is characterized in that: on the face of ampoule axis support is not set at band shape piston rod.
CN 97196192 1996-07-05 1997-06-10 Flexible piston rod Pending CN1225024A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 97196192 CN1225024A (en) 1996-07-05 1997-06-10 Flexible piston rod

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK0757/96 1996-07-05
CN 97196192 CN1225024A (en) 1996-07-05 1997-06-10 Flexible piston rod

Publications (1)

Publication Number Publication Date
CN1225024A true CN1225024A (en) 1999-08-04

Family

ID=5179624

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 97196192 Pending CN1225024A (en) 1996-07-05 1997-06-10 Flexible piston rod

Country Status (1)

Country Link
CN (1) CN1225024A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106456897A (en) * 2014-04-29 2017-02-22 崔奎东 Length-reducing syringe driving device
CN107106773A (en) * 2014-12-08 2017-08-29 赛诺菲 Drive mechanism and the delivery device with the drive mechanism
CN109414546A (en) * 2016-06-23 2019-03-01 特克法马许可公司 Segmented piston rod for medicine delivery device
CN110545861A (en) * 2017-01-17 2019-12-06 西部制药服务有限公司(以色列) Curved spring powered injector

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106456897A (en) * 2014-04-29 2017-02-22 崔奎东 Length-reducing syringe driving device
CN107106773A (en) * 2014-12-08 2017-08-29 赛诺菲 Drive mechanism and the delivery device with the drive mechanism
US10918799B2 (en) 2014-12-08 2021-02-16 Sanofi Drive mechanism and drug delivery device herewith
CN109414546A (en) * 2016-06-23 2019-03-01 特克法马许可公司 Segmented piston rod for medicine delivery device
CN110545861A (en) * 2017-01-17 2019-12-06 西部制药服务有限公司(以色列) Curved spring powered injector
CN110545861B (en) * 2017-01-17 2022-07-26 西部制药服务有限公司(以色列) Curved spring powered injector

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