CN1223369C - Osteoproliferation medicine and preparing method thereof - Google Patents

Osteoproliferation medicine and preparing method thereof Download PDF

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Publication number
CN1223369C
CN1223369C CN 03109997 CN03109997A CN1223369C CN 1223369 C CN1223369 C CN 1223369C CN 03109997 CN03109997 CN 03109997 CN 03109997 A CN03109997 A CN 03109997A CN 1223369 C CN1223369 C CN 1223369C
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China
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medicine
radix
treatment
rhizoma chuanxiong
hyperosteogeny
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CN 03109997
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CN1454620A (en
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林翠兰
卢丽萍
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Abstract

The present invention discloses a new medicine for treating hyperostosis, which is an aqueous agent or emulsion prepared by that hemlock parsley, largeleaf gentian root, safflower and uniflower swisscentaury root are used as raw materials, and respectively processed through air drying, pulverization, uniformly mixing, impregnation in container filled with aged vinegar for 24 hours, and filtration based on different characteristics of the traditional Chinese medicines. The medicine has the advantages of unique formulation and preparation method, and predominant therapeutic effect.

Description

Medicine for treating hyperosteogeny and preparation method thereof
One, technical field
The present invention relates to a kind of medicine for the treatment of hyperosteogeny, specifically, relating to a kind of is the medicine for treating hyperosteogeny that raw material is made with the vegetable Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Two, background technology
Hyperosteogeny is commonly encountered diseases, the frequently-occurring disease of middle-aged and elderly people, and bony spur compressing nervus vasculairs cause dizzy headache, lower limb severe pain, difficulty in walking, and this disease is to have a strong impact on patient's difficult and complicated illness of orthobiosis.The traditional Chinese medical science think this disease many with caused by liver and kidney deficiency, insufficiency of vital energy and blood, muscles and bones mistake support, due to pathogen invades, its treatment is so that " pathogen person disperses it, and the person that stagnates transfers its QI and blood along its gas." modern medicine thinks that this disease is to be caused by damage, chronic inflammatory disease etc., its treatment methods such as analgesias, detumescence, antiinflammatory that adopt perhaps adopt physiotherapy, to recover motor function more.If will effect a radical cure this disease still based on surgical operation, for middle-aged and elderly people, there is certain danger in operation on the one hand, and is costly on the other hand, is difficult for accepting, and the Therapeutic Method of other modern medicine is difficult to effect a radical cure this difficult diseases.
Though the Chinese patent medicine of some treatment hyperosteogenies is also arranged, because effect is not fairly obvious, the patient still has to depend on some Western medicine, even is treated surgically.At present, a kind of medicine evident in efficacy is not also found in the treatment of this disease both at home and abroad, can only play this sick symptom and suppress or lenitive therapeutic effect.
ZL93117543.7 discloses " a kind of medicine for the treatment of lumbar vertebra hyperosteogeny diseases ", its prescription is that eight flavor Chinese herbal medicine such as Flos Carthami, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Drynariae, Flos Rhododendri Mollis, Rhizoma Homalomenae, Rhizoma Coptidis, Radix Saposhnikoviae are formed, its preparation method is, Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Drynariae, Rhizoma Homalomenae, Rhizoma Coptidis, this Six-element herbal raw material of Radix Saposhnikoviae are pulverized, with Flos Carthami, Flos Rhododendri Mollis mixing, insert container then, pour 50% ethanol into and make solvent, dipping twice merges leachate.
CN1320436A discloses a kind of " medicine for treating hyperosteogeny ", and its prescription is that ten Six-element Chinese herbal medicine such as Rhizoma Chuanxiong, Radix Rehmanniae Preparata, Poria, the Cortex Eucommiae, Testa Tritici are formed, and soaks through mature vinegar to get final product in 24 hours.
Three, summary of the invention
Another object of the present invention provides the preparation method of this medicine for treating hyperosteogeny.
Purpose of the present invention aims to provide the external Chinese patent medicine of the treatment hyperosteogeny that a kind of instant effect, curative effect determine.
Technical scheme of the present invention is on the basis of secret prescription handed down in the family from generation to generation, through a large amount of clinical experiments, foundation is to the pathogenetic understanding of hyperosteogeny and the Therapeutic Principle of the traditional Chinese medical science, achieve in conjunction with modern pharmacological research, from proved recipe, filter out the natural plant of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, wind-damp dispelling, by the theory of Chinese medical science prescription, skim the cream off milk, make the effect of the softening bony spur of its performance, reducing swelling and alleviating pain, expelling wind and cold pathogens, promoting the flow of QI in the collateral by warming the meridian, blood circulation promoting and blood stasis dispelling, reach the purpose of radical cure hyperosteogeny, also the life of a health of patient.
The objective of the invention is to be achieved through the following technical solutions, each crude drug of its medicine is formed (weight portion) and being comprised:
Rhizoma Chuanxiong 15-30 Radix Gentianae Macrophyllae 8-20 Flos Carthami 8-20 Radix Rhapontici 3-10
The formula optimization scope (weight portion) of preparation medicine of the present invention is:
Rhizoma Chuanxiong 20-25 Radix Gentianae Macrophyllae 10-15 Flos Carthami 10-15 Radix Rhapontici 5-6
The optimum formula of medicine of the present invention selects (weight portion) to be:
Rhizoma Chuanxiong 30 Radix Gentianae Macrophyllae 20 Flos Carthamis 10 Radix Rhapontici 5
The preparation method of medicine of the present invention is: with this four flavors Chinese herbal medicine of Rhizoma Chuanxiong, Radix Gentianae Macrophyllae, Flos Carthami, Radix Rhapontici air-dry after, pulverize separately or pulverize in the lump places the container that fills mature vinegar to the medicated powder of mix homogeneously then, behind the dipping twenty four hours, filters.
Among the present invention, Rhizoma Chuanxiong has the effect of blood-activating and qi-promoting, wind-expelling pain-stopping, cures mainly numb limbs and tense tendons, traumatic injury, headache, rheumatic arthralgia; Radix Gentianae Macrophyllae has the effect of wind-damp dispelling, Shujin network, clearind deficient heat, cure mainly rheumatic arthralgia, the whole body or joint contracture, and brothers by, osteopyrexia and fever; The effect that Flos Carthami has blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow cures mainly traumatic injury stasis of blood pain, arthralgia; Radix Rhapontici has the effect of heat-clearing and toxic substances removing, subduing inflammation, cures mainly sore, carbuncle and painful swelling, pathogenic heat and stops up and stagnate.
Have behind the said medicine compatibility that blood circulation promoting and blood stasis dispelling, evil-wind expelling and dampness removing, anti-inflammatory analgesic, hard masses softening and resolving, Xin Wentong are stolen, the effect of active passages through which vital energy circulates.Existing example surplus this medicine treatment hyperosteogeny patient 500, cure rate reaches 90%, and effective percentage reaches 99%.And price is lower, is not restricted to one pattern on its dosage form selection, can be any external-use drug form of acceptable clinically such as water preparation, Emulsion, unguentum.By check, this prescription has no stimulation to human body skin, and safety non-toxic is evident in efficacy, and is easy to use, and healing in 5-7 days is not recurred, and does not have an injection, does not take medicine, and human body is had no side effect.
Using method: after medicine of the present invention evenly shaken, cancel malicious gauze and be converted into 8 * 12cm (4 layers), pour 10ml (milliliter) medicinal liquid then on gauze, stick on the hyperosteogeny position, hot compress (hot water bag about 40 ℃ or other thermal source all can), once a day, each about 2 hours, all be fit to treatment any time.
The animal toxicology experiment: the test of a. skin surface, select 20 of white mice, in the scope of skin area 5%, smear medicine of the present invention, dosage is 0.01 milliliter (ml), does not see toxic reaction; B. oral toxicity test with 500 times of medicine dilute with waters of the present invention, is pressed the administration of 1.34g-13.4g/ kilogram, divides to pour into from the mice mouth for three times, observes, and does not see death in 72 hours; Press the standard administration of 0.67g-1.34g/ kilogram, with 500 times of medicine dilute with waters of the present invention, the disposable celiac injection, death is not seen in observation in 72 hours, observation in 30 days all occurs dead.
Case one: Zhuan Yanqiang, man, 46 years old, 1999.10.2.
The main suit: the cervical vertebra discomfort, disease of hand, unable, headache is not healed through treatment for many years.
Diagnosis: check that through the X-ray sheet visible L3-7 vertebral body trailing edge and go up half-section and have hyperosteogeny has in various degree caused intervertebral foramina and narrowed down, and is narrowed obviously each articular facets osteosclerosis with right side L2,3,4 intervertebral foraminies.
Conclusion: hyperosteogeny of cervical vertebra
Treatment: use medicine of the present invention, consumption according to the rules and using method are treated hyperosteogeny, after five days, and patient's freedom of movement, headache disappears, and cervical vertebra bony spur disappears, and cures so far not recurrence.
Case two: Tang Guanzhen, woman, 46 years old, 2001.9.6
The main suit: flank pain, the first quarter moon of being hospitalized for treatment can not be left the bed, and can't stand up numbness of lower limbs.
Diagnosis: check that through the X-ray sheet visible lumbar vertebra both sides are hyperosteogeny in various degree, attaches most importance to the L4 stenosis of disc space with lumbar vertebra L2-4 vertebra.
Conclusion: lumbar vertebra hyperosteogeny
Treatment: use medicine of the present invention, consumption according to the rules and using method are treated hyperosteogeny, and through a drug, the walking of just can leaving the bed in second day has only mild pain; After the secondary medication, feeling of numbness disappears, transference cure after 5 days, and the energy walking freely, the patient is recurrence so far.
Case three: Tang Yi, man, 75 years old, 2000.10.7
The main suit: double knee joint pain, can not walk
Diagnosis: check that through the X-ray sheet the inside and outside spinous process of tibia of double knee joint comes to a point, interior ectocondyle reaches up and down and goes up lower edge in the patella, outer upper limb all has hyperosteogeny to form, and the joint space narrows down.
Conclusion: spinous process of tibia in two knee joints, hyperosteogeny
Treatment: use medicine of the present invention, consumption according to the rules and using method are treated the hyperosteogeny position, behind a drug, and pain relief, after the secondary medication, can walk, mild pain is arranged, still can not squat down, after three medications, rise and squat freely, it is convenient to walk, and cures and does not see recurrence so far.
Four, embodiment
Take by weighing raw material (kilogram) by following proportioning
Rhizoma Chuanxiong 30 Radix Gentianae Macrophyllae 10 Flos Carthamis 10 Radix Rhapontici 5
Production method is as follows:
With this four flavors Chinese herbal medicine of Rhizoma Chuanxiong, Radix Gentianae Macrophyllae, Flos Carthami, Radix Rhapontici air-dry after, pulverize separately or pulverize in the lump then the medicated powder mix homogeneously, places the container that fills the 100kg mature vinegar, floods 24 hours, filtration is a medicine of the present invention.

Claims (6)

1, a kind of medicine for the treatment of hyperosteogeny is characterized in that it is to be made by following raw materials by weight proportions:
Rhizoma Chuanxiong 15-30, Radix Gentianae Macrophyllae 8-20, Flos Carthami 8-20, Radix Rhapontici 3-10.
2, the medicine of treatment hyperosteogeny according to claim 1 is characterized in that the weight proportion of each crude drug is:
Rhizoma Chuanxiong 20-25, Radix Gentianae Macrophyllae 10-15, Flos Carthami 10-15, Radix Rhapontici 5-6.
3, the medicine of treatment hyperosteogeny according to claim 1 is characterized in that the weight proportion of each crude drug is:
Rhizoma Chuanxiong 30, Radix Gentianae Macrophyllae 20, Flos Carthami 10, Radix Rhapontici 5.
4, the medicine of treatment hyperosteogeny according to claim 1 is characterized in that said medicament is a said external-use drug form on any pharmaceutics.
5, the medicine of treatment hyperosteogeny according to claim 4 is characterized in that said medicament is water preparation or Emulsion.
6, the preparation method of the medicine of treatment hyperosteogeny according to claim 5, it is characterized in that Rhizoma Chuanxiong, Radix Gentianae Macrophyllae, Flos Carthami, Radix Rhapontici four flavor Chinese herbal medicine after air-dry, pulverize separately or pulverizing in the lump, then the medicated powder uniform mixing after pulverizing, place the container that fills mature vinegar again, flooded 24 hours, and filtered.
CN 03109997 2003-04-10 2003-04-10 Osteoproliferation medicine and preparing method thereof Expired - Fee Related CN1223369C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 03109997 CN1223369C (en) 2003-04-10 2003-04-10 Osteoproliferation medicine and preparing method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 03109997 CN1223369C (en) 2003-04-10 2003-04-10 Osteoproliferation medicine and preparing method thereof

Publications (2)

Publication Number Publication Date
CN1454620A CN1454620A (en) 2003-11-12
CN1223369C true CN1223369C (en) 2005-10-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 03109997 Expired - Fee Related CN1223369C (en) 2003-04-10 2003-04-10 Osteoproliferation medicine and preparing method thereof

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CN (1) CN1223369C (en)

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