CN1213994C - 制备苯乙胺衍生物的方法 - Google Patents

制备苯乙胺衍生物的方法 Download PDF

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Publication number
CN1213994C
CN1213994C CNB018209459A CN01820945A CN1213994C CN 1213994 C CN1213994 C CN 1213994C CN B018209459 A CNB018209459 A CN B018209459A CN 01820945 A CN01820945 A CN 01820945A CN 1213994 C CN1213994 C CN 1213994C
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CN
China
Prior art keywords
compound
catalyst
hydrogen
nickel
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB018209459A
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English (en)
Chinese (zh)
Other versions
CN1481354A (zh
Inventor
N·派恩甘卡
V·N·穆姆拜卡
V·S·埃昆迪
H·－P·亚莱特
U·西格里斯特
P·A·范德沙尔夫
F·比内瓦尔德
M·斯图德尔
S·伯克哈德特
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Sandoz AG
Original Assignee
Ciba Spezialitaetenchemie Holding AG
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Publication date
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Application filed by Ciba Spezialitaetenchemie Holding AG filed Critical Ciba Spezialitaetenchemie Holding AG
Publication of CN1481354A publication Critical patent/CN1481354A/zh
Application granted granted Critical
Publication of CN1213994C publication Critical patent/CN1213994C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB018209459A 2000-12-20 2001-12-12 制备苯乙胺衍生物的方法 Expired - Lifetime CN1213994C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1101CH2000 2000-12-20
IN1101/MAS/00 2000-12-20
IN390/MAS/01 2001-05-14
IN390CH2001 2001-05-14

Publications (2)

Publication Number Publication Date
CN1481354A CN1481354A (zh) 2004-03-10
CN1213994C true CN1213994C (zh) 2005-08-10

Family

ID=34117692

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018209459A Expired - Lifetime CN1213994C (zh) 2000-12-20 2001-12-12 制备苯乙胺衍生物的方法

Country Status (15)

Country Link
EP (1) EP1343750B1 (https=)
JP (1) JP4191996B2 (https=)
CN (1) CN1213994C (https=)
AR (1) AR031941A1 (https=)
AT (1) ATE287870T1 (https=)
AU (1) AU2002238421A1 (https=)
CA (1) CA2431065C (https=)
DE (1) DE60108668T2 (https=)
ES (1) ES2234918T3 (https=)
HR (1) HRPK20030590B3 (https=)
HU (1) HU225019B1 (https=)
IL (1) IL156145A0 (https=)
PT (1) PT1343750E (https=)
SI (1) SI1343750T1 (https=)
WO (1) WO2002050017A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI306092B (en) * 2003-03-11 2009-02-11 Wyeth Corp Process for preparation of phenethylamine derivatives
JP4534428B2 (ja) 2003-04-09 2010-09-01 住友化学株式会社 シクロヘキサノンオキシムの製造方法
DE10359154A1 (de) 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
WO2006067808A1 (en) * 2004-12-22 2006-06-29 Calyx Chemicals & Pharmaceuticals Private Limited An improved process for production of intermediate of antidepressant agent
CN100364966C (zh) * 2005-04-14 2008-01-30 上海雅本化学有限公司 1－[2－氨基－1－(对甲氧苯基)乙基]环己醇甲酸盐的合成方法
WO2008013993A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
FR2909089B1 (fr) * 2006-11-23 2009-02-27 Ppg Sipsy Soc Par Actions Simp Procede in situ ou "one pot" d'hydrogenation et d'amination reductrice
WO2009037953A1 (ja) * 2007-09-19 2009-03-26 Mitsui Chemicals, Inc. アルコールの製造方法および酸処理ラネー触媒
WO2009070311A2 (en) 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Crystal forms of o-desmethylvenlafaxine fumarate
WO2010046808A2 (en) * 2008-10-21 2010-04-29 Alembic Limited A process for the preparation of venlafaxine hydrochloride
CN102093233A (zh) * 2009-12-09 2011-06-15 上海华理生物医药有限公司 一种制备1-[2-氨基-1-(对甲氧基苯基)乙基]环己醇盐酸盐的方法
WO2011121452A2 (en) 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
CN111500651B (zh) * 2020-04-10 2023-07-28 宁波酶赛生物工程有限公司 一种苯乙胺的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives

Also Published As

Publication number Publication date
CN1481354A (zh) 2004-03-10
JP4191996B2 (ja) 2008-12-03
AR031941A1 (es) 2003-10-08
IL156145A0 (en) 2003-12-23
EP1343750A1 (en) 2003-09-17
CA2431065A1 (en) 2002-06-27
CA2431065C (en) 2010-11-02
HRPK20030590B3 (en) 2006-11-30
PT1343750E (pt) 2005-05-31
HU225019B1 (en) 2006-05-29
SI1343750T1 (en) 2005-06-30
DE60108668T2 (de) 2005-06-30
AU2002238421A1 (en) 2002-07-01
JP2004520312A (ja) 2004-07-08
DE60108668D1 (de) 2005-03-03
HRP20030590A2 (en) 2005-06-30
HUP0302594A3 (en) 2005-12-28
ATE287870T1 (de) 2005-02-15
EP1343750B1 (en) 2005-01-26
WO2002050017A1 (en) 2002-06-27
ES2234918T3 (es) 2005-07-01
HUP0302594A2 (hu) 2003-11-28

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C06 Publication
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SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
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Owner name: SANDOZ CO., LTD.

Free format text: FORMER OWNER: CIBA SPECIALTY CHEMICALS HOLDING INC.

Effective date: 20060818

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20060818

Address after: Basel, Switzerland

Patentee after: Sandoz Ltd.

Address before: Basel, Switzerland

Patentee before: Ciba Specialty Chemicals Holding Inc.

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20050810