CN1213542A

CN1213542A - External-use ointment for treating atrophic arthritis

Info

Publication number: CN1213542A
Application number: CN97106134A
Authority: CN
Inventors: 王令喜
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-10-06
Filing date: 1997-10-06
Publication date: 1999-04-14
Anticipated expiration: 2017-10-06
Also published as: CN1058889C

Abstract

An external-used ointment for treating rheumatoid arthritis is prepared from 22 Chinese-medicinal materials such as antler gelatin, astragalus root, eucommia bark, Chinese angelica root, grass-leaved sweetflag rhizome, etc.

Description

The external-applied ointment of treatment rheumatoid arthritis

The present invention relates to a kind of external-applied ointment for the treatment of rheumatoid arthritis, the ointment that the pure Chinese crude drug of specifically a kind of usefulness is made is used for the external application for curing of rheumatoid arthritis.

The rheumatoid arthritis disease, the traditional Chinese medical science is referred to as arthromyodynia, and it becomes the master with osteoarthritis, and modern medicine thinks that this disease owing to the immune system confusion causes, still do not have the radical cure method so far.The traditional Chinese medical science is with a long history to the treatment research of this disease, and the innerwear outer treatment method is more, and curative effect is also progressively improving." Heilungkiang Chinese medicine " the 4th phase in 1997, the 54th～57 page, published that Mr. Lv Junying by No.1 Hospital Attached to Guangxi Medical Univ. writes, exercise question is the survey article of " external treatment with Chinese medicine rheumatoid arthritis recent developments ".The 1st part has been enumerated the situations such as distinct methods, medication and therapeutic effect of external treatment of tcm in the literary composition, as one, usefulness insensitive impediment gas bath side such as Chen Yunwang: Radix Aconiti Kusnezoffii, Radix Aconiti, spill ten each 20g of flavor Chinese medicine such as the Radix Paeoniae Alba, Herba speranskiae tuberculatae, and to different symptoms plus-minus prescription, carry out gas bath and treat 48 examples, alleviate 6 examples, produce effects 20 examples, effective 19 examples, invalid 3 examples, total effective rate are 93.7%.Two, Chen Zhuojun adopts Chinese medicine to give birth to ten flavors such as river bird, Radix Aconiti Kusnezoffii, Rhizoma Arisaematis, Rhizoma Pinelliae, Herba Asari, Olibanum, smokes afterwards to wash earlier and soaks the affected part again, treatment patient 25 examples, produce effects 11 examples, 13 examples that take a turn for the better, invalid 1 example, total effective rate 96%.Three, self-control such as Koryo gram numbness is loose, and be the end altogether with 17 flavor Chinese medicines such as Radix Saposhnikoviae, Radix Stephaniae Tetrandrae, Radix Gentianae Macrophyllae, Ramulus Mori, Pheretima, Sanguis Draxonis, Scorpio, and the thermal image person transfers with vinegar and applies, and the cold person of elephant transfers with wine and applies, and cold and heat resemble not obvious person and transfer deposited with Mel.30 routine patient's produce effects 16 examples, effective 11 examples, total effective rate 90%.Four, Zhou Cuiying etc. adopts prescriptions of Chinese medicine such as Semen Strychni, Olibanum, Herba Ephedrae, Herba speranskiae tuberculatae, Herba Asari, Radix Glycyrrhizae, and levigation is treated 43 examples with the external application of Oleum sesami furnishing pasty state, produce effects 33 examples, and effective 8 examples, total effective rate is 95.3%.Embrocate the Chinese medicine method in addition, middle lesser sage's lamp therapeutic instrument penetrates Chinese medicine method totally 9 kinds of situations, has all obtained better effects.But above-mentioned each side is all less than the situation of curing, and above-mentioned mostly are some prescriptions of controlling because of disease executing, still do not have a general character and reach the degree of production.

Purpose of the present invention is exactly the deficiency at this class disease of external therapy of Chinese herb, and the external Chinese medicine ointment of the high treatment rheumatoid arthritis of a kind of curative effect is provided.

The present invention is based on the research to rheumatoid arthritis traditional Chinese medical science mechanism, think that primary disease is because of the human body Qi and blood deficiency, positive QI-insufficiency due to Liver and kidney is insufficiency of the spleen, autoimmune function is low, and is multiple because of overworking, daily life is not normal, factor such as puerperal or weakness due to chronic disease causes Wei Yang not solid, and the heresy of striae of the skin and muscles being loose, rheumatism cold and heat is taken advantage of a weak point, and causes QI and blood not smooth, meridians numbness hinders, the damp-phlegm stasis of blood is turbid solidifies, and rich knot muscle muscles and bones joint forms rheumatoid arthritis.So select vigorate qi and replenish the blood for use, the kidney warming nourishing the liver, stomach function regulating spleen invigorating, disperse blood stasis and dredge collateral, hard masses softening and resolving, expelling wind and cold, removing damp-heat, reducing swelling and alleviating pain class Chinese crude drug, control modification through examination for many years, and overcome the deficiency of traditional black plaster, adhesive plaster with medicine, develop the technical program, it is characterized in that being made by pure Chinese crude drug, each Chinese crude drug and the parts by weight proportioning of forming it are:

Colla cornus cervi 40～80, the Radix Astragali 30～60, the Cortex Eucommiae and Radix Angelicae Sinensis each 20～40, Rhizoma Acori Graminei, Fructus Gleditsia, FENGXIAN each 18～35, Herba Leonuri 17～35, Bombyx Batryticatus, Herba Taraxaci, Herba Siegesbeckiae, Rhizoma Chuanxiong each 16～30, Rhizoma Atractylodis, Agkistrodon, Rhizoma Et Radix Notopterygii each 15～30, Radix Clematidis, Radix Gentianae Macrophyllae each 12～25, Scolopendra, Rhizoma Curcumae Longae each 10～20, Herba Asari, Camphora each 6～10, Moschus 0.2～0.6.

The parts by weight optimum ratio of forming each Chinese crude drug of the present invention is: Colla cornus cervi 60～70, the Radix Astragali 40～50, Radix Angelicae Sinensis, the Cortex Eucommiae 30～40, Rhizoma Acori Graminei, Fructus Gleditsia, FENGXIAN, Herba Leonuri, Bombyx Batryticatus, Herba Taraxaci, Herba Siegesbeckiae, Rhizoma Chuanxiong, Rhizoma Atractylodis, Agkistrodon, Rhizoma Et Radix Notopterygii each 20～30, Radix Clematidis, Radix Gentianae Macrophyllae, Scolopendra, Rhizoma Curcumae Longae each 15～20, Herba Asari, Camphora each 6～10, Moschus 0.4～0.6.

Because the technical program is reused the Radix Astragali, Radix Angelicae Sinensis vigorate qi and replenish the blood, Colla cornus cervi, the nourishing the liver of Cortex Eucommiae the kidney warming, strengthening the tendons and bones are mended congenital smart the dominator of QI, and the source of selecting Rhizoma Acori Graminei, the spleen invigorating of Rhizoma Atractylodis stomach function regulating to promote the diet benefit QI and blood day after tomorrow is monarch drug altogether; Join Herba Leonuri, FENGXIAN, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, Rhizoma Chuanxiong, Rhizoma Curcumae Longae blood-activating and qi-promoting, inducing menstruation to relieve menalgia, Fructus Gleditsia, Bombyx Batryticatus dispelling pathogenic wind and eliminating phlegm, hard masses softening and resolving are ministerial drug altogether; 5 Agkistrodons, the deep wind of searching of Scolopendra, removing obstruction in the collateral to relieve pain, Rhizoma Et Radix Notopterygii, Herba Asari expelling wind and cold, Herba Taraxaci, Herba Siegesbeckiae heat-clearing and toxic substances removing, the dehumidifying detumescence, Radix Clematidis, Radix Gentianae Macrophyllae wind-damp dispelling, the meridian dredging, muscles and tendons relaxing to alleviate pain are assistant altogether; The Camphora easing joint movement is opened all keys, the dampness pain relieving, and Moschus is hot fragrant deep, and disperse blood stasis and dredge collateral, reducing swelling and alleviating pain draw the through sick be total to of all medicines for making.So trial edition ointment treatment rheumatoid arthritis 166 examples have obtained the high remarkable result of curative effect, the treatment situation sees the following form:

Trial edition ointment treatment rheumatoid arthritis 166 routine categorised statistical forms

By the sex syndrome-classification	The man	The woman	Amount to	????％	Rheumatism and arthritis	The rheumatism pyretic arthralgia	Amount to	????％
By the sex syndrome-classification	The man	The woman	Amount to	????％	Rheumatism and arthritis	The rheumatism pyretic arthralgia	Amount to	????％	The example number	????99	????67	????166		????133	????33	????166
Cure	????70	????47	????117	?70.5％	????90	????27	????117	?70.5％	The example number	????99	????67	????166		????133	????33	????166
Cure	????70	????47	????117	?70.5％	????90	????27	????117	?70.5％	Produce effects	????20	????14	????34	?20.5％	????28	????6	????34	?20.5％
Effectively	????9	????6	????15	????9％	????15		????15	????9％	Produce effects	????20	????14	????34	?20.5％	????28	????6	????34	?20.5％
Effectively	????9	????6	????15	????9％	????15		????15	????9％	Age-based classification	Below 20 years old	21～30 years old	31～40 years old	41～50 years old	51～60 years old	More than 61 years old
The example number	????26	????43	????40	????26	????16	????15	????166		Age-based classification	Below 20 years old	21～30 years old	31～40 years old	41～50 years old	51～60 years old	More than 61 years old
The example number	????26	????43	????40	????26	????16	????15	????166		Cure	????21	????33	????28	????22	????8	????5	????117	?70.5％
Produce effects	????4	????7	????8	????3	????6	????6	????34	?20.5％	Cure	????21	????33	????28	????22	????8	????5	????117	?70.5％
Produce effects	????4	????7	????8	????3	????6	????6	????34	?20.5％	Effectively	????1	????3	????4	????1	????2	????4	????15	????9％
By the medical history classification	Below 1 year	1～2 year	2～4 years	4～6 years	6～10 years	More than 10 years			Effectively	????1	????3	????4	????1	????2	????4	????15	????9％
By the medical history classification	Below 1 year	1～2 year	2～4 years	4～6 years	6～10 years	More than 10 years			The example number	????21	????36	????48	????21	????23	????17	????166
Cure	????20	????30	????38	????11	????10	????8	????117	?70.5％	The example number	????21	????36	????48	????21	????23	????17	????166
Cure	????20	????30	????38	????11	????10	????8	????117	?70.5％	Produce effects	????1	????4	????7	????7	????10	????5	????34	?20.5％
Effectively		????2	????3	????3	????3	????4	????15	????9％	Produce effects	????1	????4	????7	????7	????10	????5	????34	?20.5％
Effectively		????2	????3	????3	????3	????4	????15	????9％	By the treatment time classification was 1 course of treatment in 1 month	3～4	5～6	7～8	9～10	11～12	More than 12
The example number	????31	????39	????43	????27	????16	????10	????166			3～4	5～6	7～8	9～10	11～12	More than 12

Cure	????26	????29	????30	????20	????8	????4	????117	?70.5％
Cure	????26	????29	????30	????20	????8	????4	????117	?70.5％	Produce effects	????5	????9	????7	????3	????6	????4	????34	?20.5％
Effectively		????1	????6	????4	????2	????2	????15	????9％	Produce effects	????5	????9	????7	????3	????6	????4	????34	?20.5％
Effectively		????1	????6	????4	????2	????2	????15	????9％	Total effective rate								??100％

The present invention is further described as follows below in conjunction with embodiment, implement a concrete technical scheme of the present invention, be that the ratio of weight and number of forming its each Chinese crude drug is: Colla cornus cervi 65, the Radix Astragali 45, Radix Angelicae Sinensis 35, the Cortex Eucommiae 30, Rhizoma Acori Graminei, Fructus Gleditsia, FENGXIAN, Herba Leonuri, Bombyx Batryticatus, Herba Taraxaci, Herba Siegesbeckiae, Rhizoma Chuanxiong, Rhizoma Atractylodis, Agkistrodon, Rhizoma Et Radix Notopterygii each 25, Radix Clematidis, Radix Gentianae Macrophyllae, Scolopendra, Rhizoma Curcumae Longae each 18, Herba Asari, Camphora each 8, Moschus 0.5.

About the method for making of ointment of the present invention, the firstth, at first take by weighing each clean Chinese crude drug by the technical scheme proportioning; The secondth, Colla cornus cervi system end is added the water heating make glue; The 3rd is above-mentioned other 19 flavor Chinese medicines except that Colla cornus cervi, Camphora, Moschus three flavor Chinese medicines to be added water decoct medicinal herbs, and takes out the medicinal residues after-filtration, and reheat is boiled into the extractum of the beading that drips; The 4th is to mix thoroughly in glue that Camphora, the last adding of Moschus system is above-mentioned and the extractum, promptly gets this ointment.This ointment usage is to stick in the affected part, changes once in per three days, generally is every month course of treatment.

This ointment also is applicable to rheumatic arthritis, the external application for curing of ankylosing spondylitis.

Claims

1, a kind of external-applied ointment for the treatment of rheumatoid arthritis is characterized in that it is made up of pure Chinese crude drug, and the ratio of weight and number of each Chinese crude drug is as follows:

2, the external-applied ointment of treatment rheumatoid arthritis as claimed in claim 1, the ratio of weight and number that it is characterized in that forming its each Chinese crude drug is:

Colla cornus cervi 60～70, the Radix Astragali 40～50, the Cortex Eucommiae and Radix Angelicae Sinensis each 30～40, Rhizoma Acori Graminei, Fructus Gleditsia, FENGXIAN, Herba Leonuri, Bombyx Batryticatus, Herba Taraxaci, Herba Siegesbeckiae, Rhizoma Chuanxiong, Rhizoma Atractylodis, Agkistrodon, Rhizoma Et Radix Notopterygii each 20～30, Radix Clematidis, Radix Gentianae Macrophyllae, Scolopendra, Rhizoma Curcumae Longae each 15～20, Herba Asari, Camphora each 6～10, Moschus 0.4～0.6.

3, the external-applied ointment of treatment rheumatoid arthritis as claimed in claim 1 or 2, the ratio of weight and number that it is characterized in that forming its each Chinese crude drug is:

Colla cornus cervi 65, the Radix Astragali 45, Radix Angelicae Sinensis 35, the Cortex Eucommiae 30, Rhizoma Acori Graminei, Fructus Gleditsia, FENGXIAN, Herba Leonuri, Bombyx Batryticatus, Herba Taraxaci, Herba Siegesbeckiae, Rhizoma Chuanxiong, Rhizoma Atractylodis, Agkistrodon, Rhizoma Et Radix Notopterygii each 25, Radix Clematidis, Radix Gentianae Macrophyllae, Scolopendra, Rhizoma Curcumae Longae each 18, Herba Asari, Camphora each 8, Moschus 0.5.