CN1212103C - Circumferentia weld throttling type cryoprobe - Google Patents

Circumferentia weld throttling type cryoprobe Download PDF

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CN1212103C
CN1212103C CN 02149355 CN02149355A CN1212103C CN 1212103 C CN1212103 C CN 1212103C CN 02149355 CN02149355 CN 02149355 CN 02149355 A CN02149355 A CN 02149355A CN 1212103 C CN1212103 C CN 1212103C
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probe
cryoprobe
return pipe
girth
throttle
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CN1480103A (en
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柯钢
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柯钢
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Abstract

本环缝节流式冷冻探针:连通高压气源的连接接头从冷冻手术治疗机的主机上引出,通过连接导管进入手柄内腔,并与和手柄相通的探针相连通,探针包括探针杆、位于探针杆内并由其轴心处向外依次同心放置的回流管和绝热套管,绝热套管的长度短于回流管,二者之间形成起高压气体节流和气体回热双重作用的环形狭缝,回流管前端部与探针杆间形成使气流在其中快速流动以增强换热效果的换热环形狭缝,在探针头部内与回流管前端部之间形成汽缸Ⅱ;还可在回流管前端装一与温度仪表相连的电偶式温度传感器,汽缸Ⅱ前端装有翅片式回热器;探针头部形状为锥形针尖状、斜切形针尖状或圆头形针尖状;具有直径和创伤更小,结构简单、易制作、价格低廉等优点。 This cryoprobe girth throttle formula: high pressure air source connected to the communication connector drawn from the host machine cryosurgery, through the connecting conduit into the lumen of the handle, and handle communication with the probe and communicating the probe comprises probe the needle bar, which is located within the probe shaft axis by successively concentrically disposed outwardly at reflux tube and insulating sleeve, the sleeve is shorter than the length of the heat insulating reflux tube, formed from the high-pressure gas and return gas throttle therebetween heat dual role annular slit between the distal end portion of the return pipe of the probe shaft is formed in which the rapid flow of the gas stream to enhance the heat transfer effect of a heat exchanger annular slit is formed between the distal end portion of the return pipe in the probe head ⅱ cylinder; galvanic further temperature sensor means connected to the front end of the return pipe and a temperature meter, a front end of the cylinder ⅱ finned type regenerator; probe needle-like shape of the head is tapered, beveled acicular needle-like or round shape; and having a diameter less invasive, simple structure, easy manufacture, low cost advantages.

Description

环缝节流式冷冻探针 Throttle cryoprobe girth

发明领域本发明属于外科手术中用于冷却人体局部组织,以达到摧毁癌细胞或良性肿瘤细胞、神经暂时阻断的外科手术器械,特别涉及一种外科手术中用于摧毁癌细胞或良性肿瘤细胞的环缝节流式冷冻探针。 FIELD OF THE INVENTION The present invention is in the local tissue cooling body for surgery, in order to destroy cancer cells or benign tumor cells reach the nerve to temporarily block the surgical instrument, particularly to a surgical procedure to destroy the cancer cells or benign tumor cells the meter-girth cryoprobe.

背景技术 Background technique

通过冷冻细胞对活性组织结构进行破坏的外科手术通常被用于摧毁癌细胞和良性肿瘤细胞。 Surgical destruction of the cells by freeze viable tissue structures are commonly used to destroy cancer cells and benign cells. 冷冻手术也被用于神经暂时阻断以达到开刀手术后一定的时间内止痛的目的。 Cryosurgery is also used to temporarily block the neural purposes reached within a certain time after surgery for pain. 相对于开刀手术,低温外科手术有许多优点:快捷,几乎无痛,无需局部麻醉,无术后感染的风险,几乎不留下疤痕。 Relative to open surgery, cryosurgery has many advantages: quick, almost painless, no local anesthesia, without the risk of postoperative infection, almost no scarring.

通过冷冻手术造成细胞破坏的机理为:1、如果组织被缓慢冷却,细胞会大量失去水份,使细胞中有害电解质浓度提高,导致组织坏死;2、如果组织被快速冷却,将形成多而微小的冰晶,使得冰晶细化,此时细胞不易损坏。 The mechanism of cell damage caused by cryosurgery: 1, if the organization is slowly cooled, the cells will lose a lot of water, electrolyte concentration of harmful cells increase, leading to tissue necrosis; 2, if the organization is rapidly cooling, the formation of many and small ice crystals, such ice thinning when the cells were not damaged. 但在融化过程中,如果冰到水的相变太快,所有的冰晶被简单熔化。 But in the melting process, if the water to ice phase change is too fast, all of the ice is simply melted. 如果融化速度降下来,将发生已经融化的冰晶要冷却其周围的组织,从而使得一些水再次形成冰,再结晶过程将使得一些冰晶被加长而形成冰锋,冰锋刺破细胞壁导致细胞死亡,从而使组织坏死。 If the rate of melting down, the ice had melted the cooling will occur to the surrounding tissue, so that some of the water to form ice again, some of the recrystallization process will cause ice to form ice front is lengthened, ice front puncture cell walls leading to cell death, so that tissue necrosis.

3、新陈代谢继续的时候,冰阻碍细胞营养的供应和代谢物的处理,细胞死亡就发生。 3, metabolic continue when the ice hinder cell nutrition treatment, supplies and cell death metabolites occurs.

外科手术可以使用干冰、液氮等冷冻源直接应用于待处理的组织。 The surgery may dry ice, liquid nitrogen source applied directly frozen tissue to be treated. 最简单的方法是用棉签蘸上液体制冷剂,然后用浸透制冷剂的棉球直接接触处理部位,或者将制冷剂导入一封闭的金属导管,通过金属导管喷射制冷剂至应用部位而实施冷冻手术。 The easiest way is to use a cotton swab dipped in the liquid refrigerant, and then with a cotton ball soaked in direct contact with the refrigerant treatment site, or the refrigerant introduced into a closed metal pipe, the metal pipe through the refrigerant injection to the site of application and embodiment cryosurgical . 然而,这种方法有许多不如意的地方:(1)用蘸或喷的方法,直接使用制冷剂会造成组织快速冷冻,导致冰晶细化而不是形成大冰晶,细胞不容易脱水,减小了通过高电解浓度来破坏细胞的发生。 However, this method has many unhappy place: (1) a method of spraying or dipping, direct use of the refrigerant can cause tissue snap frozen, ice crystals results in the formation of large ice crystals instead of thinning, the cells are not easily dehydrated, reduced by high concentration electrolytic cell destruction occurs. 当制冷剂离开以后,热量又从身体里向被冻组织传递,导致相对快速融化,不宜形成冰锋,从而减少了使细胞遭受破坏程度。 When the refrigerant leaves the heat transfer to and from the body to be frozen tissue, leading to relatively rapid melting, ice should form a front, thereby reducing the extent of the damage suffered cells. 直接使用制冷剂于局部组织的最大问题是无法控制冷冻面积的大小,无法控制冷冻程度,冷冻时间和升温时间。 The biggest problem of the refrigerant directly to the local tissue is unable to control the size of the freezing area, can not control the degree of freezing, freezing time, and heating time.

1961年Cooper首先应用液氮作为冷源,采用将液氮通过封闭的金属管道,在一定压力下流至管的尖端,借助液氮的汽化降温作用可使受冻局部温度降达-190℃左右。 Cooper 1961 the first application of liquid nitrogen as a cold source, by using liquid nitrogen closed metal pipe, at a constant pressure downstream of the tube to the tip, the cooling effect by vaporization of liquid nitrogen cold can reduce the local temperature of about -190 ℃. 他用此装置治疗了100例帕金森氏综合症。 He used the device 100 patients treatment Parkinson's disease.

使用液氮作为冷源制成的手术器械,已经被广泛使用。 Using liquid nitrogen as a cold source made of surgical instruments, it has been widely used. 特别是皮肤科中对于痣类、粉刺、雀斑、疣等的治疗。 Especially in dermatology class for moles, acne, freckles, warts treatment. 然而,液氮冷冻手术器械在许多方面不能令人满意。 However, liquid nitrogen cryosurgery instruments in many respects unsatisfactory. 首先,由于液氮冷冻探头由三根同心管构成,中心为液氮输进管,中间为返流气体同心管环形夹层,最外部为真空保温同心管环形夹层。 First, since the liquid nitrogen cryoprobe consists of three concentric tubes, the central tube is liquid nitrogen input, intermediate of the gas reflux tube concentric annular dissection outermost concentric tubes an annular vacuum insulation interlayer. 这样,液氮仅适用于大冷冻探头,而对于较小的冷冻头而言,液氮在冷冻头尖端的蒸发会出现严重问题:由于从尖端返回,四周的排出氮气使部分液氮加热,可使供给管内的液氮蒸发。 Thus, only for large liquid nitrogen cryoprobe, freezing for smaller head, the liquid nitrogen serious problems in evaporation of probe tip: Since the return from the tip, so that the surrounding portion of the liquid nitrogen, the nitrogen gas is heated, can be so that nitrogen in the supply tube evaporator. 这是因为排出的氮气比供给管中的液氮温度要高,形成了逆流热交换,而使供给管中液氮部分蒸发形成气体,而形成阻碍液氮流到尖端的氮气气泡。 This is because the ratio of the liquid nitrogen temperature of the nitrogen supply tube discharge is higher, the formation of countercurrent heat exchange, the liquid nitrogen in the supply tube is formed partially evaporated gas formed of nitrogen bubbles impede tip nitrogen flow. 加大液氮压力或降低液氮温度可使液氮过冷,从而解决这个问题。 Increase the pressure of liquid nitrogen or liquid nitrogen can reduce the temperature of liquid nitrogen cold, so as to solve this problem. 但是这又使得系统更为复杂;其次,液氮使用不方便,设备操作复杂。 But it also makes the system more complex; secondly, the use of liquid nitrogen is inconvenient, complicated equipment operation.

以气体作为冷媒,依靠焦尔-汤姆逊节流效应制冷的方法受到人们的重视和欢迎。 With gas as a refrigerant, relying on Joule - Thomson throttling effect of the cooling method of people's attention and welcome. 常温下的高压氧气、氮气和二氧化碳等气体流经一节流小孔,气体膨胀以后会产生制冷效应称为焦尔-汤姆逊节流效应。 Hyperbaric oxygen at normal temperature, nitrogen gas and carbon dioxide gas through a throttle hole, the cooling effect is generated after the gas expander called Joule - Thomson throttling effect. 专利GB-2,337,000利用这个原理而发明的冷冻治疗机,其结构为高压气体从最里层的小管中流过,在探针的头部有一节流小孔,气体通过节流温度降低,然而这种冷冻探针的针杆全部都是在低温状态,不能满足有些手术的要求,特别是对于经皮冷冻治疗,除了冷冻探针的针尖以外,探针的其他部分必须保持常温,否则,将会造成手术应用部位之外的正常组织冻伤。 Patent GB-2,337,000 using this principle and machine cryotherapy invention, having the structure of high pressure gas from the innermost layer fluid in the pipe is too small, there is a throttling orifice in the head of the probe, the gas temperature is lowered by throttling, however all kinds cryoprobe needle bar is at a low temperature, can not meet the requirements of some surgery, particularly for percutaneous cryotherapy, except for the tip of the cryoprobe, the other portion of the probe must be kept at room temperature, otherwise, would cause application site outside of normal tissue surgery frostbite. Longsworth于1994年在冷冻探针里设计了一个螺旋管回热式换热器,专利US-5,452,582,其结构为如图6所示,在探针内有一螺旋管,高压气体从螺旋管的管内走过,在探针头部气体经小孔节流以后成为低压低温气体。 Longsworth 1994 cryoprobe designed in a recuperative heat exchanger coil, patent US-5,452,582, having the structure shown in Figure 6, has a spiral, the high pressure gas from within the probe tube spiral through, by a low pressure after the restrictor orifice cryogenic gas in the probe head gas. 低温低压气体从螺旋管的外部掠过,从而螺旋管成为一回热式换热器,使得回流气体不断升温,而进气气流又可以得到有效地预冷,从而,使得探针的温度沿针杆方向形成温度梯度,探针的针尖温度最低,而探针靠近手柄的位置几乎为常温。 Temperature low-pressure gas passing from the outside of the coil, thereby becoming a spiral recuperative heat exchanger, so that the gas heats up to reflux, and the intake airflow can be pre-cooled effectively, so that the temperature of the probe along the needle lever direction a temperature gradient, the lowest temperature of the probe tip, and the probe is close to the position of the handle is almost at room temperature. Mikus等进一步发展了这项发明,专利US-58000487,其结构为如图7所示,他们不仅采用带翅片的螺旋管以增加换热效率,而且,还在换热器的外部设计了绝热材料的保温层,从而使得探针针杆外部接近常温,但该带翅片的螺旋管式探针,由于内置螺旋管换热器,探针直径不可能做得很小,满足不了冷冻微创伤手术的需求(冷冻微创伤手术需要直径为2mm或更小的探针)。 Mikus et further development of the invention, the patent US-58000487, having the structure shown in FIG. 7, they not only use spiral finned to increase the heat exchange efficiency, and, also the external heat exchanger designed adiabatic insulation material, such that the needle bar outside the probe close to room temperature, but the finned coil probe, since the built-in coil heat exchanger, the diameter of the probe can not be made very small, can not meet freeze invasive trauma surgery demand (need to freeze minimally invasive surgery having a diameter of 2mm or less probes).

发明内容 SUMMARY

本发明的目的在于克服上述结构复杂和螺旋管直径的限制所存在的缺陷,而提供一种供冷冻手术用的直径更小,创伤更小的具有微创伤效果的冷冻手术器械—环缝节流式冷冻探针,从而满足微创伤冷冻手术的要求,而且其结构更加简单、容易制作、价格较低廉。 Object of the present invention is to overcome the drawbacks and limitations of the above-described structure is complicated tube having a diameter that is present, and to provide a cryosurgical diameter for a smaller, less invasive cryosurgical instrument having a minimally invasive effect - girth section streaming cryoprobe, in order to meet the requirements of the minimally invasive cryosurgical, and its structure is more simple, easy to manufacture, less expensive.

本发明的技术方案如下:本发明提供的冷冻探针,包括连接接头111、连接导管222、手柄333和探针444,连通高压气源的连接接头111从冷冻手术治疗机的主机上引出,通过连接导管222进入手柄333内的内腔,并与和手柄333相连通的探针444相连通,其特征在于,所述探针444包括探针杆777、位于探针杆777之内并由探针杆777的轴心处向外依次同心放置的回流管999和绝热套管888,绝热套管888的长度短于回流管999的长度,在绝热套管888与回流管999之间形成起到高压气体节流和气体回热的双重作用的环形狭缝771,回流管999前端部与探针杆777之间形成使气流在其中快速流动以增强换热效果的换热环形狭缝772,在探针444头部内与回流管999前端部之间形成汽缸II;还可进一步包括安装在回流管999前端侧壁上的电偶式温度传感器122,电偶式温度传感器122的导线123穿过回流管999 Aspect of the present invention is as follows: the present invention provides the cryoprobe, connecting joint 111 includes a connection joint 111, connected to the conduit 222, the handle 333 and the probe 444, the high pressure air source communicated drawn from the host machine cryosurgery, by connecting duct 222 into the lumen 333 in the handle, and the handle 333 and communicating with the probe 444 is connected through, characterized in that, the probe 444 includes a probe shaft 777 by the probe 777 located within the probe shaft the axis of the needle bar 777 disposed concentrically outwardly sequentially return pipe 999 and the insulating bushing 888, insulating sleeve 888 is shorter than the length of the return pipe 999 is formed between the insulating sleeve 888 functions as the return pipe 999 a double-acting annular slit 771 and the high-pressure gas throttling back the hot gases, is formed between the distal end portion 777,999 with the return pipe in which the probe shaft fast flowing gas stream to enhance the heat transfer effect of a heat exchanger annular slit 772, in within the probe head 444 is formed between the distal end portion of the return pipe 999 and the cylinder II; may further comprise electrically coupling temperature sensor 122 is mounted on the front end of the side wall of the return pipe 999, the wire thermocouple temperature sensors 122 through 123 return pipe 999 内腔并依次经过手柄333、连接导管222及一三通124与温度仪表125相连;所述的汽缸II的前端装有翅片式回热器121,其翅片形状为螺纹形或齿形;所述探针444头部形状为锥形针尖状、斜切形针尖状或园头形针尖状;所述探针444的探针杆777为柔性的加强聚酰胺软管,其直径在1.2-5mm之间,长度在100-1500mm之间;所述绝热套管888的材质为导热率低的非金属材料,如导热率低的塑料或玻璃钢;所述换热环形狭缝772的长度在3~30mm之间,间隙在0.05-0.3mm之间;所述环形狭缝771的长度为100~1450mm之间,间隙在0.01-0.02mm之间;所述回流管999的材质为导热率高的金属材料,如紫铜或不锈钢。 And sequentially passes through the handle lumen 333, connector 222 and conduit 124 is connected to a three-way temperature meter 125; the front end of the finned cylinder type II regenerator 121, which is a thread-like or fin-shaped tooth; the probe head 444 is tapered needle-like shape, acicular shape or chamfered shape round head shaped tip; the probe 444 of the probe shaft 777 is a flexible reinforcing polyamide hose diameter 1.2 between 5mm, a length between 100-1500mm; the insulating sleeve made of nonmetallic material with low thermal conductivity, low thermal conductivity, such as plastic or fiberglass 888; length of the annular slit 772 in the heat exchanger 3 between ~ 30mm, the gap between 0.05-0.3mm; length of the annular slit 771 is between 100 ~ 1450mm, a gap between 0.01-0.02mm; material of the tube 999 having high thermal conductivity is refluxed metallic material such as copper or stainless steel.

使用时,高压气源由连接接头111从冷冻手术治疗机的主机上引出,然后经过连接导管222进入手柄333内,在手柄333内进行气源分配以后,气源流向探针444;在手柄333内进行分配以后的气源,流向由绝热套管888和回流管999形成的环形狭缝771;由于气体存在粘性,气体在狭缝的进口和出口之间流动时将形成压力差,从而,在狭缝前后气体的比容将突然增大,实现焦耳-汤姆逊节流效应,达到使气体制冷降温的目的。 After use, the high-pressure gas source is connected to the host adapter 111 drawn out from the cryosurgical treatment machine, and then through the connecting conduit 222 into the handle 333, for air distribution within the handle 333, gas source 444 to the probe; the handle 333 after the allocation of the gas source, the flow of the annular slit is formed by the insulating sleeve 888 and the return conduit 999,771; due to viscosity of the gas, the gas flows between the inlet and the outlet slit of a pressure difference, so that, in hematocrit slit around the gas will increase abruptly realized Joule - Thomson throttling effect, to make gas refrigeration cooling purposes. 经膨胀以后的低温气体在由探针杆777、探针杆头部110和回流管999之间所围成的空间即汽缸II内将冷量传递给探针杆头部,最后从回流管999返回手柄333,经气流分配以后沿连接导管222,通过连接接头111返回冷冻手术治疗机的主机。 Low temperature gas expands after the cylinder II i.e. to pass by the probe shaft 777, the probe shaft between the head and the return conduit 110 into a space 999 surrounded by the cold head to the probe shaft, from the return conduit 999 and finally returns a handle 333, through the air distribution along the connecting duct after 222, the host returns cryosurgical treatment machine 111 via the connection joint.

狭缝回热式换热器的传热是通过回流管的管壁热导来实现的。 Slot heat recuperative heat exchanger is achieved through the walls of the thermal conductivity of the return conduit. 高温侧:狭缝中的来流气体通过气体对流的方式将热量传递给回流管的管壁;低温测:管壁将由高温侧传递过来的热量又通过对流的方式传递给管内的回流气体。 Temperature side: to the gas flow slit to the wall of the heat transfer through the gas reflux tube convection; low temperature test: heat transfer from the pipe wall by the high temperature side and passed to the return gas in the tube by convection. 这样高温侧的温度降低,低温侧的温度提高,从而实现了回热;回热的作用主要有三点:其一是降低来流气体的温度,从而使得膨胀以后的温度更低;其二是提高制冷能力,减少耗气量;其三是沿针杆的轴向方向形成温度梯度:离针尖越远,针杆的温度越高,这将非常有利于经皮冷冻手术的实施;本发明的绝热套管888可更进一步降低探针杆的温度,隔绝探针杆内气流的低温;回流管采用导热良好的金属材料制成,可增加径向传热,减小轴向传热;回热式换热器的作用是可回收冷头没有被利用(传热给冷冻组织)的冷量,使得进气气流的温度被回流逐步降低,从而使得冷冻探针的温度沿针杆方向形成温度梯度。 Such high temperature side temperature decreases, the temperature of the low temperature side is increased, thereby achieving a regenerator; effect regenerator three main points: one is to reduce the temperature of the gas stream, so that the lower temperature after expansion; the other is to improve the cooling capacity, reduced air consumption; the third is the axial direction of the needle bar of a temperature gradient: farther away from the tip, the higher the temperature of the needle bar, which will be very beneficial percutaneous cryosurgery embodiment; insulating sleeve according to the present invention tube 888 can further reduce the temperature of the probe shaft, the probe shaft isolated cryogenic gas stream; reflux tube made of a metal material using good thermal conductivity, increased radial heat transfer, to reduce the axial heat transfer; recuperative heat exchange effect is to heat the cold head is not utilized recoverable (to heat frozen tissue) in cold, so that a temperature of intake airflow is reduced gradually to reflux, the temperature along the needle bar so that the direction of the cryoprobe temperature gradient. 本发明的冷冻探针的绝热套管888和回流管999之间形成的环形狭缝771既是回热式换热器又是气体节流器,起到了双重的作用。 An annular slit is formed between the insulating sleeve 888 and the return pipe 999 of the present invention cryoprobe 771 both recuperative heat exchanger is a gas throttle, it plays a dual role.

所以,本发明提供的冷冻探针具有结构简单,易于制作,探针的直径可以做的更小而且仅探针头部处于0℃以下的低温状态,针杆的其他部位均高于0℃,从而真正实现探针小,手术微创伤。 Therefore, the present invention provides the cryoprobe has a simple structure, easy to manufacture, the probe diameter may be made smaller and the probe head only at low temperature below 0 deg.] C, the other parts of the needle bar higher than 0 deg.] C, thus truly small probe, minimally invasive surgery.

附图说明 BRIEF DESCRIPTION

附图1和附图2分别为本发明的结构示意图;附图3和附图4分别为探针444的结构示意图;附图5-1、附图5-2和附图5-3分别为不同形状探针头部110的结构示意图;附图6为现有技术中US 5,452,582的结构示意图;附图7为现有技术中US 5,800,488的结构示意图;其中:连接接头111 连接导管222 手柄333探针444 针杆555 探针针杆777绝热套管888 回流管999 探针头部110汽缸II 电偶式温度传感器122翅片式回热器122 电偶式温度传感器引线123附图6中各部件的标号如下:低温探头10 薄壁金属管12 冷头14常温端16 长塑料管18 热交换器20高压气体进气管22 冷头域26 毛细管28中空心轴30 返流气体31 隔套32热交换器33 温度传感器34 翅片管35 Figures 1 and 2 are schematic structural diagram of the present invention; Figures 3 and 4 are structural schematic drawings of the probe 444; figures 5-1, figures 5-2 and figures 5-3 respectively different shape of the probe head portion 110 of the schematic structure; Figure 6 is a schematic structural diagram of the prior art US 5,452,582; Fig. 7 is a schematic structural diagram of the prior art US 5,800,488; and wherein: the connection joint 111 is connected to conduit 222 of the handle 333 probe 6. each pin member 444 probes the needle bar a needle bar 555 777 999 insulating sleeve 888 return pipe 110 of the cylinder head of the probe electrically coupling temperature sensors 122 II fin recuperator 122 thermocouple temperature sensor lead 123 to the accompanying drawings the following reference numerals: low temperature thin-walled metal tube 12 of the probe 10 a cold head end 20 of the high pressure gas at room temperature 14 16 18 long plastic tube heat exchanger 22 cooling the intake pipe 28 in the header 26 of the hollow shaft 30 of the capillary gas reflux heat exchanger 31 of the spacer 32 33 temperature sensor 34 fin tubes 35

第二温度传感器36附图7中各部件的标号如下::高压进气管14 引流管19 热交换器20冷却流体出口端21 焦耳-汤姆逊喷嘴22 膨胀腔23端堵头24 心轴25 间隙26间隙27 翅片28 壳30热电偶29具体实施方式下面结合附图及实施例进一步描述本发明:由图1-4可知,本发明提供的冷冻探针,包括连接接头111、连接导管222、手柄333和探针444,连通高压气源的连接接头111从冷冻手术治疗机的主机上引出,通过连接导管222进入手柄333内的内腔,并与和手柄333相连通的探针444相连通,其特征在于,所述探针444包括探针杆777、位于探针杆777之内并由探针杆777的轴心处向外依次同心放置的回流管999和绝热套管888,绝热套管888的长度短于回流管999的长度,在绝热套管888与回流管999之间形成起到高压气体节流和气体回热 Reference numeral 7 members in each of the second temperature sensor 36 follows the high pressure intake pipe 14 :: reference draft tube 19 heat exchanger 20 the cooling fluid outlet end 21 Joule - Thomson expansion chamber 23 of the nozzle 22 end block 24 the spindle 25 gap 26 be seen from Figure 1-4, the present invention provides the cryoprobe, including connection joint 111, connected to the conduit 222, the handle: the fin gap 27 28 housing the thermocouple 30 and 29 DETAILED dESCRIPTION the following examples further describe the present invention in conjunction with the accompanying drawings probes 333 and 444, the communication connection joint 111 is drawn from the high pressure air source cryosurgery host machine, into the cavity 222 in the handle 333 is connected via conduit 333 and the handle and communicating with the probe 444 in communication, wherein the probe 444 includes a probe shaft 777, the axis of the probe shaft 777 by the concentrically disposed successively outwardly reflux tube 999 and insulating sleeve 888 is located within the probe shaft 777, the insulating sleeve 888 is shorter than the length of the return pipe 999, 888 is formed between the insulating sleeve and the return pipe 999 functions as the throttle pressure gas and a gas recuperator 的双重作用的环形狭缝771,回流管999前端部与探针杆777之间形成使气流在其中快速流动以增强换热效果的换热环形狭缝772,在探针444头部内与回流管999前端部之间形成汽缸II;还可进一步包括安装在回流管999前端侧壁上的电偶式温度传感器122,电偶式温度传感 122的导线123穿过回流管999的内腔并依次经过手柄333、连接导管222及一三通124与温度仪表125相连;所述的汽缸II的前端装有翅片式回热器121,其翅片形状为螺纹形或齿形;所述探针444头部形状为锥形针尖状、斜切形针尖状或园头形针尖状;所述探针444的探针杆777为柔性的加强聚酰胺软管,其直径在1.2-5mm之间,长度在100-1500mm之间;所述绝热套管888的材质为导热率低的非金属材料,如导热率低的塑料或玻璃钢;所述换热环形狭缝772的长度在3~30mm之间,间隙在0.05-0.3mm之间;所述环形狭缝771的长度为10 777 is formed between the double-acting annular slits 771, 999 and the probe distal end portion of the return pipe in the gas stream wherein the rod to enhance the heat transfer effect of the fast flow exchanger annular slits 772, 444 in the probe head and the reflux II cylinder tube 999 is formed between the distal end portion; may further include an electrical coupling temperature sensor 122 is mounted on the front end of the side wall 999 of the return pipe, temperature sensing thermocouple wire 122 through the lumen 123 and return pipe 999 sequentially passes through the handle 333, and 222 connected to conduit 124 connected to a three-way temperature meter 125; the front end of the finned cylinder type II regenerator 121, which is a thread-like or fin-shaped tooth; said probe a needle head portion 444 is tapered needle-like shape, acicular shape or chamfered shape round head shaped tip; the probe 444 of the probe shaft 777 is a flexible hose reinforcing polyamide, a diameter of between 1.2-5mm length between 100-1500mm; the insulating bushing 888 is made of non-metallic material of low thermal conductivity, low thermal conductivity, such as plastic or fiberglass; length of the slit of the annular heat exchanger 772 in the 3 ~ 30mm between, the gap between 0.05-0.3mm; length of the annular slit 771 is 10 0~1450mm之间,间隙在0.01-0.02mm之间;所述回流管999的材质为导热率高的金属材料,如紫铜或不锈钢。 Between 0 ~ 1450mm, a gap between 0.01-0.02mm; the return pipe 999 made of metal material having high thermal conductivity, such as copper or stainless steel.

如图5-1、图5-2、图5-3所示,探针头部110的形状可以根据用途不同设计成锥形针尖状、斜切形针尖状或园头形针尖状。 Figure 5-1, Figure 5-2, Figure 5-3, the shape of the probe tip 110 may be designed according to different uses needle-like tapered, beveled or rounded head acicular needle-like shape.

如图4所示,为增加换热效果,在汽缸II内可以安装一翅片式换热器121,以增大换热面积和增加扰度,以增强换热。 4, to increase the heat transfer effect, may be mounted in the cylinder II a finned heat exchanger 121 to increase the heat transfer area and increasing the degree of interference, to enhance heat transfer.

如图4所示,可以在回流管中预制一热电偶温度传感器122,热电偶温度传感器122的引线123从回流管999的内腔穿出并依次经过手柄333、连接导管222及一个三通124与冷冻治疗机上的温度仪表125相连。 As shown in FIG 4, a thermocouple temperature sensor can be prefabricated in the return pipe 122, the thermocouple temperature sensor leads 123,122 and sequentially piercing through the handle 333, the return pipe 999 is connected from the lumen 222 of conduit 124 and a three-way temperature meter 125 is connected to the machine cryotherapy. 以测量探针头部110内气体的温度。 110 to measure the temperature of the gas probe head.

如图2所示,冷冻探针杆777可以做成柔性的,例如采用加强聚酰胺软管作为探针针杆材料。 2, the cryoprobe flexible rod 777 can be made of, for example, using a polyamide reinforcing material hose as a probe needle bar.

在一个探针杆直径为2mm或5mm的实施例中,探针长度400mm(可根据需要,可做得较长《可长至1500mm》,也可做得较短《可短至100mm),探针杆选用1Cr18Ni9Ti材料;绝热套管选用绝热性能良好的聚四氟乙烯材料,壁厚0.3mm。 In a probe shaft having a diameter of 2mm or 5mm embodiment, the probe length 400mm (according to need, it can be made longer, "can grow to 1500mm", also can be made shorter "may be as short as 100mm), Probe 1Cr18Ni9Ti material selected needle bar; good insulation properties selected thermal insulation sleeve made of Teflon, a wall thickness of 0.3mm. 冷冻探针的探针杆头部110做成斜切针头的形状。 Cryoprobe probe club head 110 made of a shape chamfered needle.

在另一实施例中,探针杆直径为1.2mm,探针长度260mm。 In another embodiment, the probe shaft diameter of 1.2mm, probe length 260mm. 探针杆选用1Cr18Ni9Ti材料;绝热套管选用聚四氟乙烯材料,壁厚0.2mm;冷冻探针的探针杆头部做成锥形针头的形状。 1Cr18Ni9Ti material selected probe shaft; PTFE insulating sleeve selection, wall thickness 0.2mm; probe club head made of cryoprobe shape of the tapered needle.

在一个实施例中,冷冻手术治疗机采用高压氩气作为冷煤,通过焦耳-汤姆逊节流制冷,通过本发明的狭缝回热换热的方式,在冷冻探针的头部上可获得-120℃的低温,而探针杆上的温度高于0℃。 In one embodiment, cryosurgery machine with high pressure argon as Freons, by the Joule - Thomson expansion refrigeration, back through the slit of the present invention, the heat exchanger of the embodiment, obtained on the head of the cryoprobe -120 ℃ low temperature, while the probe rod temperature above 0 ℃.

在另一个实施例中,冷冻手术治疗机采用饱和二氧化碳作为冷煤,通过焦耳-汤姆逊节流制冷,在冷冻探针的头部上可获得-75℃的低温,而探针杆上的温度高于0℃。 In another embodiment, cryosurgery saturated with carbon dioxide as the Freons machine, by the Joule - Thomson expansion refrigeration obtained at low temperature -75 ℃ on the head of the cryoprobe, and a temperature probe rod greater than 0 ℃.

Claims (10)

1.一种环缝节流式冷冻探针,包括连接接头(111)、连接导管(222)、手柄(333)和探针(444),连通高压气源的连接接头(111)从冷冻手术治疗机的主机上引出,通过连接导管(222)进入手柄(333)内的内腔,并与和手柄(333)相连通的探针(444)相连通,其特征在于,所述探针(444)包括探针杆(777)、位于探针杆(777)之内并由探针杆(777)的轴心处向外依次同心放置的回流管(999)和绝热套管(888),绝热套管(888)的长度短于回流管(999)的长度,在绝热套管(888)与回流管(999)之间形成起到高压气体节流和气体回热的双重作用的环形狭缝(771),回流管(999)前端部与探针杆(777)之间形成使气流在其中快速流动以增强换热效果的换热环形狭缝(772),在探针(444)头部内与回流管(999)前端部之间形成汽缸(II)。 A meter-girth cryoprobe comprising a connecting joint (111), connecting conduit (222), the handle (333) and the probe (444), high pressure air source is connected to the communication connector (111) from the cryosurgical extraction treatment on the host machine, communicating a probe (444) communicating into the lumen in the handle (333) connected via conduit (222), and with a handle (333), characterized in that the probe ( 444) comprises a probe shaft (777), located within the probe shaft (777) of the probe by a rod (777) outwardly of the axis of sequentially disposed concentrically return pipe (999) and insulation sleeve (888), double-acting annular insulating sleeve length (888) is shorter than the return pipe (999), and between the insulating sleeve (888) and the return pipe (999) is formed and functions as a high-pressure gas the gas throttling regenerative narrow slits (771) formed between the return pipe (999) and the distal portion of the probe shaft (777) in which the rapid flow of the gas stream to enhance the heat transfer effect of a heat exchanger annular slit (772), probe (444) head the inner cylinder is formed between the return pipe portion (999) and the distal end portion (II).
2.按权利要求1所述的环缝节流式冷冻探针,其特征在于,还包括安装在回流管(999)前端侧壁上的电偶式温度传感器(122),其导线(123)穿过回流管(999)的内腔并依次经过手柄(333)、连接导管(222)及一三通(124)与温度仪表(125)相连。 2. girth claim throttle refrigerator probe of claim 1, characterized in further comprising mounting a reflux tube (999) electrically coupling temperature sensor (122) on the front end side walls, which leads (123) a lumen through the return pipe (999) and sequentially passes through the handle (333), connecting conduit (222) and a three-way (124) and a temperature meter (125) is connected.
3.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述的汽缸(II)的前端装有翅片式回热器(121),其翅片形状为螺纹形或齿形。 3. Throttle claim girth cryoprobe or claim 2, wherein the front end of the cylinder (II) is provided with finned recuperator (121), which is a fin-shaped a threaded or toothed shaped.
4.按权利要求1或2所述的用于冷却人体局部组织的环缝节流式冷冻探针,其特征在于,所述探针(444)头部形状为锥形针尖状、斜切形针尖状或园头形针尖状。 4. girth claim throttle refrigeration for cooling the probe body local tissue claim 1 or 2, characterized in that the probe (444) needle-like shape of the head is tapered, beveled needle-like or needle-like shape round head.
5.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述探针(444)的探针杆(777)为柔性的加强聚酰胺软管,其直径在1.2-5mm之间,长度在100-1500mm之间。 5. Throttle claim girth cryoprobe or claim 2, wherein the flexible hose polyamide reinforcing the probe (444) of the probe shaft (777) of which the diameter between 1.2-5mm, length between 100-1500mm.
6.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述绝热套管(888)的材质为导热率低的非金属材料。 6. Throttle claim girth cryoprobe or claim 2, wherein the insulating material sleeve (888) is a low thermal conductivity nonmetallic material.
7.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述绝热套管(888)的材质为导热率低的塑料或玻璃钢。 7. Throttle claim girth cryoprobe or claim 12, wherein the insulating material sleeve (888) is a low thermal conductivity plastic or fiberglass.
8.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述换热环形狭缝(772)的长度为3~30mm之间,间隙在0.05-0.3mm之间。 8. The length of the slit orifice ring according to claim cryoprobe formula 1 or claim 2, characterized in that said heat exchanger annular slot (772) is between 3 ~ 30mm, a gap of 0.05-0.3mm between.
9.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述回流管(999)的材质为导热率高的金属材料。 9. Throttle claim girth cryoprobe or claim 2, wherein the tube (999) is made of a metal material having high thermal conductivity of the reflux.
10.按权利要求1或2所述的环缝节流式冷冻探针,其特征在于,所述环形狭缝(771)的长度为100~1450mm之间,间隙在0.01-0.2mm之间。 10. The sewing ring of claim meter-cryoprobe claim 1 or 2, characterized in that the length of the annular slot (771) is between 100 ~ 1450mm, a gap between 0.01-0.2mm.
CN 02149355 2002-09-03 2002-11-13 Circumferentia weld throttling type cryoprobe CN1212103C (en)

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CN 02149355 CN1212103C (en) 2002-09-03 2002-11-13 Circumferentia weld throttling type cryoprobe

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US7189228B2 (en) 2003-06-25 2007-03-13 Endocare, Inc. Detachable cryosurgical probe with breakaway handle
CN100408001C (en) 2005-04-14 2008-08-06 北京库蓝医疗设备有限公司 Disposable freezing probe
JP2011516168A (en) * 2008-04-01 2011-05-26 ザ ジェネラル ホスピタル コーポレイション Method and apparatus for cooling biological tissue
US7967815B1 (en) * 2010-03-25 2011-06-28 Icecure Medical Ltd. Cryosurgical instrument with enhanced heat transfer
CN101893357A (en) * 2010-07-26 2010-11-24 雷宜东 Three-way throttle valve
US9108453B2 (en) 2011-11-23 2015-08-18 R.R. Donnelley & Sons Company Sortable notepad
US8864177B2 (en) 2011-11-23 2014-10-21 Esselte Corporation Movable highlight strip

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