CN1208653A - Medicine for treating carsickness and method for preparing same - Google Patents
Medicine for treating carsickness and method for preparing same Download PDFInfo
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- CN1208653A CN1208653A CN 98120045 CN98120045A CN1208653A CN 1208653 A CN1208653 A CN 1208653A CN 98120045 CN98120045 CN 98120045 CN 98120045 A CN98120045 A CN 98120045A CN 1208653 A CN1208653 A CN 1208653A
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Abstract
The present invention discloses a medicine for curing carsickness and its preparation method. It is made up by using the Chinese medicinal materials of orange peel, mint, fresh ginger, chrysanthemum, saussurea root and agastache/patchouli as raw materials, and adopting the processes of proportioning, crushing and soaking them in white liquor. When said medicine is used, its volatile components are inhaled by mouth or nose, so that it is convenient in use, has no toxic side effect, and its therapeutic effect is obvious, and its cost is low.
Description
The present invention relates to the medicine of a kind of treatment motion sickness (carsickness), is raw material with the Chinese herbal medicine specifically, is the Chinese patent medicine of solvent preparation with Chinese liquor, and dosage form is the mouth and nose inhalant, the invention still further relates to the preparation method of this medicine.
Motion sickness be carsick, seasick, airsick and by wave, jolt, the general name of various factors associated diseases such as rotation, accelerated motion.Carsickness is wherein a kind of, be everlasting and take place after riding several minutes to a few hours, modern medicine is not clear fully as yet to its pathogeny, its inducement more complicated, high temperature, high humidity, improper ventilation, noise, unhappy abnormal smells from the patient, nervous, do not have enough sleep, overtired, hunger or satiety, physical weakness, disease of inner ear etc. all bring out primary disease easily.During outbreak, first sense epigastric discomfort, is in a cold sweat at nauseating, the pale complexion of having continued; After have dizzy, spirit depressing, salivation to increase, vomit.Blood pressure drops can be arranged, breathe multiple performance such as dark and slow, nystagmus, symptom generally disappears in tens of minutes and several hours in out of service or the back of slowing down or alleviates.
At present, treatment is much more carsick uses oral drugs, mainly uses antihistaminic and Semen daturae class medicine, can be separately or use in conjunction, and also can add and use other drug, vomit available metoclopramide; Calm with stable, phenobarbital etc.The weak point of this class medicine is that time of beginning of drug effect is longer, need take before 1 hour in travelling, and the time that drug action continues is also longer more, if short distance is ridden, because of the side effect that carsickness is taken medicine, must influence work orthobiosis after getting off.In addition, side effect such as slight carsickness is taken also can produce xerostomia, drowsiness, nauseating, blurred vision behind this class medicine, bring out glaucoma, tired, so more than do not adopt.
Purpose of the present invention is intended to overcome above-mentioned shortcoming, the Chinese patent medicine of the treatment carsickness that providing a kind of length to travel all on the way can use, good effect, can play a role rapidly, have no side effect.
Another object of the present invention provides the preparation method of this carsickness therapeutic agent.
Solution of the present invention is based on motherland's medical science and carsick institute is occurred pathogenetic understanding of symptom and Therapeutic Principle such as dizziness, nauseating, vomiting, at the thorny problem that runs in the present carsick therapeutic process, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out the natural Chinese medicinal herb that eliminating turbid pathogen with aromatics is sensible, ward off dirty refreshment preventing or arresting vomiting, by the theory of Chinese medical science prescription, creatively be carrier simultaneously with wine, make volatile medicament, the mode medication is gone in the through port snuffing, thereby reaches the effect of refreshment pain relieving, stopping nausea and vomiting by lowering the adverse flow of QI and middle treatment carsickness.
Medicine of the present invention is made (consumption is a weight portion) by following component:
Pericarpium Citri tangerinae 40-100 part Herba Menthae 10-30 part Rhizoma Zingiberis Recens 5-30 part
Flos Chrysanthemi 3-15 part Radix Aucklandiae 1-3 part Herba Pogostemonis 1-3 part
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Pericarpium Citri tangerinae 45-80 part Herba Menthae 10-20 part Rhizoma Zingiberis Recens 5-20 part
Flos Chrysanthemi 5-10 part Radix Aucklandiae 1-2 part Herba Pogostemonis 1-2 part
The optimum weight proportioning of medicine of the present invention is:
18 parts in 10 portions of Rhizoma Zingiberis Recenss of 60 portions of Herba Menthaes of Pericarpium Citri tangerinae
1 part of 1 portion of Herba Pogostemonis of 9 parts of Radix Aucklandiae of Flos Chrysanthemi
The preparation method of medicine of the present invention is:
Get Pericarpium Citri tangerinae, Herba Menthae, Rhizoma Zingiberis Recens, Flos Chrysanthemi, the Radix Aucklandiae, Herba Pogostemonis earlier, with their pulverize separately is coarse powder, low temperature sterilization is pressed described mixed with whole drug powder components then, puts in the extraction pot, added soaking in Chinese liquor 5-7 days down at 16 ℃-25 ℃, volatile oil to medicine fully is dissolved in the wine, goes dregs, filters, clarification makes the carsick volatile medicine of treatment.
Pericarpium Citri tangerinae, Herba Menthae are monarch in the present invention's prescription, and the hot hardship of loosing of Pericarpium Citri tangerinae is fallen, and fragrance is amusing, and drying dampness to eliminate phlegm is arranged, the merit of stomach function regulating preventing or arresting vomiting; The Herba Menthae awakening consciousness is warded off dirty evil, and the refresh oneself is arranged, the effect of refreshment; The two all return lung meridian and and be monarch drug, one rise and one drop helps that lung qi a surname sends out, respectful falling, the lung is concerned with QI of the whole body, lung qi is logical transfers disease then dizzy, vomiting and nausea to be subdued.Rhizoma Zingiberis Recens, Flos Chrysanthemi are minister, and the effect that Rhizoma Zingiberis Recens has good preventing or arresting vomiting town to tell has the title of " patient suffering from habitual vomiting panacea ", can help Pericarpium Citri tangerinae to increase the power of preventing or arresting vomiting; The sharp vim and vigour of Flos Chrysanthemi, clear fragrant catharsis can be controlled diseases such as dizziness, dizzy, feeling of fullness in the head, headache.The Radix Aucklandiae, Herba Pogostemonis are for helping, and the Radix Aucklandiae is fragrant and dry, can rise and can fall, logical reason three warmers, outstanding benefaction stagnation of QI in spleen and stomach, and the merit of receipts stomach function regulating preventing or arresting vomiting; The Herba Pogostemonis heresy of being good at loosing is warded off evil, regulating QI to expel dampness, preventing or arresting vomiting and in, for taste are told contrary key medicine.Chinese liquor is for making, the gas welding of wine own, matter is clear, the bitter in the mouth suffering is sweet, bitter can sending down the abnormal ascending QI, suffering has the plug of loosing to stagnate, and opens stasis of blood knot, the meridian dredging, promoting the circulation of blood feeling pulse merit, its gas welding can guide all medicines to prove effective rapidly.
An important feature of the present invention is to contain abundant volatile oil composition in the medicament, and it is the material of main performance curative effect in this medicament, and modern pharmacological research shows has better curative effect to carsickness.As: contain volatile oil in the Pericarpium Citri tangerinae, wherein be mainly limonene, gastrointestinal smooth muscle is had relexation, can resist the spasm due to barium chloride, the pilocarpine; Secondly contain volatile oil in the Herba Menthae, Main Ingredients and Appearance is a menthol, is menthone etc., and end sensor and produce creeping chill slightly can excite nerve; The mixture of isolated zingiberone and ginger ketenes has the town to tell effect from Rhizoma Zingiberis Recens; Contain volatile oil, saussurine etc. in the Radix Aucklandiae, some lactone in its volatile oil and go in ester oil the smooth muscle spasm effect of removing is arranged, the guinea pig bronchial that the alkaloid part causes histamine and the spasm of intestinal smooth muscle have tangible spasmolysis; Volatile oil in the Herba Pogostemonis can suppress the too drastic wriggling of gastrointestinal.
Volatile oil is a kind of active ingredient that has therapeutical effect in the medicine, have aromatic odor mostly, can volatilize voluntarily at normal temperatures and do not stay any oil stain, be soluble in organic solvent and the fatty oil, can molten entirely (dissolving in water be minimum, is oily liquids) in the ethanol more than 70%.The Main Ingredients and Appearance of medicine generation drug action of the present invention is its contained volatile oil, through the steeping in wine bubble, is dissolved in the wine, and medicament enters human body with the volatilization of wine by mucosa during use, and borrows the guiding function of wine to prove effective rapidly.
Another important feature of the present invention is that contained active ingredient is abundant in the medicament, is to be guidance with the Chinese medicine property theory, extracts gained in natural Chinese medicinal herb, combination of compounds on the non-simple meaning.
Compared with prior art, the present invention has following advantage:
1, to select natural Chinese medicinal herb for use be raw material in the present invention, do not have any chemical essence, nontoxic to human body.
2, medicament of the present invention is the volatility dosage form, need not be oral, and the through port snuffing goes into to use, and still can use when vomiting.
3, the present invention is fit to length uses of travelling on the way, can play a role rapidly when carsickness occurring in way by bus, after stopping using, also has no side effect, and patients with mild is had health-care effect.
For showing the therapeutic effect of medicine of the present invention to carsickness, we have carried out system investigation to 50 routine patients at random on the bus of 10-600 kilometer, the respondent is the passenger who carsick symptom is arranged and carsick history is arranged, and has or once had one of following symptom person to be the respondent: feel sick in (1) dizziness, (2) epigastric discomfort, (3) unhappiness, (4) headache, (5) order distending pain, (6), vomit (7), (8) other pathological symptom that produces because of carsickness.The object of observation is divided into three groups: the A group: vomiting history B group is arranged: do not have the vomiting history, symptom is lighter; C group: do not have carsick history but carsick symptom is arranged.Observed result is as follows:
Example number transference cure sx symptom still takes place
A organizes 10 63 |
B organizes 32 27 5/
C organizes 88 //
3 examples are promptly used this medicine in the A group after getting on the bus, and have 2 examples not see carsick symptom, have 1 routine symptom to alleviate more in the past and do not have vomiting, slight dizzy back use is appearring in all the other 7 examples, 4 routine transference cures are arranged, have 2 routine symptoms to alleviate more in the past and do not have vomiting, 1 routine all diseases alleviate but still vomit (being considered as symptom still takes place), obvious effective rate 60%, 27 routine symptoms disappear conscious no pain, 5 routine sxs substantially in the effective percentage 90% B group, obvious effective rate is 84.38%, effective percentage 100%; The C group is all used this product, 8 routine transference cures, obvious effective rate 100% after slight carsick symptom occurring.
In sum, with medicament of the present invention 50 routine patients are done therapeutic test, total obvious effective rate is 82%, and total effective rate is 98%.
Embodiment:
Take by weighing raw material (consumption is a weight portion) by following proportioning:
18 parts in 10 portions of Rhizoma Zingiberis Recenss of 60 portions of Herba Menthaes of Pericarpium Citri tangerinae
1 part of 1 portion of Herba Pogostemonis of 9 parts of Radix Aucklandiae of Flos Chrysanthemi
Preparation method is as follows:
Get Pericarpium Citri tangerinae, Herba Menthae, Rhizoma Zingiberis Recens, Flos Chrysanthemi, the Radix Aucklandiae, Herba Pogostemonis earlier, with their pulverize separately is coarse powder, low temperature sterilization is pressed described mixed with whole drug powder components then, puts in the extraction pot, the soaking in Chinese liquor of adding 53% under 16 ℃-25 ℃ 5 days, volatile oil to medicine fully is dissolved in the wine, goes dregs, filters, clarification makes the carsick volatile medicine of treatment.
Claims (8)
1, a kind of medicine for the treatment of carsickness is characterized in that it is the medicament of being made by the following weight proportion raw material (consumption is a weight portion):
Pericarpium Citri tangerinae 40-100 part Herba Menthae 10-30 part Rhizoma Zingiberis Recens 5-30 part
Flos Chrysanthemi 3-15 part Radix Aucklandiae 1-3 part Herba Pogostemonis 1-3 part
2, the carsick medicine of treatment according to claim 1 is characterized in that the weight proportion scope of each raw material is:
Pericarpium Citri tangerinae 45-80 part Herba Menthae 10-20 part Rhizoma Zingiberis Recens 5-20 part
Flos Chrysanthemi 5-10 part Radix Aucklandiae 1-2 part Herba Pogostemonis 1-2 part
3, the carsick medicine of treatment according to claim 1, the weight that it is characterized in that each raw material are joined:
18 parts in 10 portions of Rhizoma Zingiberis Recenss of 60 portions of Herba Menthaes of Pericarpium Citri tangerinae
1 part of 1 portion of Herba Pogostemonis of 9 parts of Radix Aucklandiae of Flos Chrysanthemi
4, according to claim 1, the carsick medicine of 2 or 3 described treatments, it is characterized in that said medicament is the mouth and nose inhalant.
5, the carsick medicine of treatment according to claim 4 is characterized in that said medicament is the agent of volatility medicated wine.
6, a kind of method for preparing the carsick medicine of the described treatment of claim 5, it is characterized in that: get Pericarpium Citri tangerinae, Herba Menthae, Rhizoma Zingiberis Recens, Flos Chrysanthemi, the Radix Aucklandiae, Herba Pogostemonis earlier, with their pulverize separately is coarse powder, and low temperature sterilization is pressed described mixed with whole drug powder components then, put in the extraction pot, added soaking in Chinese liquor 5-7 days down at 16 ℃-25 ℃, the volatile oil to medicine fully is dissolved in the wine, goes dregs, filter, clarify, make the carsick volatility medicated wine of treatment.
7, the preparation method of the medicine of treatment carsickness according to claim 6, the alcoholic strength that it is characterized in that described Chinese liquor is 38%-75%.
8, the preparation method of the medicine of treatment carsickness according to claim 6, the alcoholic strength that it is characterized in that described Chinese liquor is 53%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98120045A CN1056312C (en) | 1998-09-28 | 1998-09-28 | Medicine for treating carsickness and method for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98120045A CN1056312C (en) | 1998-09-28 | 1998-09-28 | Medicine for treating carsickness and method for preparing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1208653A true CN1208653A (en) | 1999-02-24 |
| CN1056312C CN1056312C (en) | 2000-09-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98120045A Expired - Fee Related CN1056312C (en) | 1998-09-28 | 1998-09-28 | Medicine for treating carsickness and method for preparing same |
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| Country | Link |
|---|---|
| CN (1) | CN1056312C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423467A (en) * | 2011-03-14 | 2012-04-25 | 王圣文 | Edible and medicinal liquid used for preventing carsickness |
| CN103212053A (en) * | 2013-05-13 | 2013-07-24 | 于贺贺 | Medicine for treating carsickness and preparation method of medicine |
| CN103330931A (en) * | 2013-07-19 | 2013-10-02 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine sachet for preventing and curing carsickness |
| CN103798436A (en) * | 2014-02-27 | 2014-05-21 | 青岛崂好人海洋生物技术有限公司 | Carsickness relieving tea |
| CN105520878A (en) * | 2015-12-30 | 2016-04-27 | 苏州宏久航空防热材料科技有限公司 | Anti-carsickness non-woven fabric wet wipe |
| CN106108176A (en) * | 2016-07-08 | 2016-11-16 | 何彩芳 | A kind of Anti-carsickness mask |
| CN106237271A (en) * | 2015-06-10 | 2016-12-21 | 云南白药集团无锡药业有限公司 | A kind of hydrogel application carsick for prevention and alleviation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090502A (en) * | 1993-02-03 | 1994-08-10 | 曹青春 | Medicine for promoting digestion and preparation method thereof |
-
1998
- 1998-09-28 CN CN98120045A patent/CN1056312C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423467A (en) * | 2011-03-14 | 2012-04-25 | 王圣文 | Edible and medicinal liquid used for preventing carsickness |
| CN103212053A (en) * | 2013-05-13 | 2013-07-24 | 于贺贺 | Medicine for treating carsickness and preparation method of medicine |
| CN103212053B (en) * | 2013-05-13 | 2015-07-01 | 于贺贺 | Medicine for treating carsickness and preparation method of medicine |
| CN103330931A (en) * | 2013-07-19 | 2013-10-02 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine sachet for preventing and curing carsickness |
| CN103330931B (en) * | 2013-07-19 | 2015-05-27 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine sachet for preventing and curing carsickness |
| CN103798436A (en) * | 2014-02-27 | 2014-05-21 | 青岛崂好人海洋生物技术有限公司 | Carsickness relieving tea |
| CN103798436B (en) * | 2014-02-27 | 2015-07-22 | 青岛崂好人海洋生物技术有限公司 | Carsickness relieving tea |
| CN106237271A (en) * | 2015-06-10 | 2016-12-21 | 云南白药集团无锡药业有限公司 | A kind of hydrogel application carsick for prevention and alleviation |
| CN105520878A (en) * | 2015-12-30 | 2016-04-27 | 苏州宏久航空防热材料科技有限公司 | Anti-carsickness non-woven fabric wet wipe |
| CN106108176A (en) * | 2016-07-08 | 2016-11-16 | 何彩芳 | A kind of Anti-carsickness mask |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1056312C (en) | 2000-09-13 |
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