CN1208643A - Medicine for treating prostatosis and method for preparing same - Google Patents

Abstract

The Chinese medicine for curing prostatic disorders is formed from the Chinese medicinal materials of pangolin scales, American ginseng, astragalus root, cornus fruit, lycium berry, deerhorn glue, lygodium spore, notoginseng root, rice-paper plant pith, cistanche stem, coptis root, alisma tuber, polyporus, pipe-fish, antelope horn, tortoise plastron glue, golden hairpin dendrobium stem and phellodendron bark. Its preparation method includes the following steps: deep-frying pangolin scales in sesame oil until scorch, stir-frying coptis root with vinegar, stir-frying phellodendron bark with salt, baking other medicinal materials to remove toxicity, grinding, screening with 120-mesh sieve, water-grinding, pilling, drying, UV irradiation for 48hr, sterilization, bottling and wax-sealing. Said invention possesses the functions of enriching and supplementing the liver and kidney, supplementing the spleen and boosting qi and quickening blood and transforming stasis, etc..

Description

A kind of medicine for the treatment of prostatosis and preparation method thereof

The present invention relates to a kind of Chinese herb medicine preparation, relate in particular to a kind of prepared from traditional Chinese medicines product for the treatment of prostatosis and preparation method thereof.

Chronic prostatosis is a kind of commonly encountered diseases of male reproductive system, frequently-occurring disease.According to statistics, policlinic Urology Surgery prostatic diseases accounts for 25～30%, and the male that its sickness rate accounted for more than 21.53%, 35 years old in the rural area suffers from this type of disease up to 35～40%, and its sickness rate of the male old man more than 60 years old is more than 80%.Although there are a lot of antibiotic to come out, the primary disease sickness rate there is no obvious decline, and curative effect is still dissatisfied, though the surgery of chronic prostate hyperplasia can solve unobstructed micturition, and local symptom and chronic inflammatory disease still can't be eradicated, and patient is very painful.

Motherland's medical science does not have prostatitic title, clinical position and researcher are thought and are belonged to the category that " pouring ", " turbid ", " excessive in vain ", " smart turbid " wait disease more, the traditional Chinese medical science has been developed many pharmaceutical formulations to the clinical treatment of primary disease in recent years, adopt medicine typing to execute the common typing of method of treatment such as the hepatic and renal YIN deficiency, damp invasion of lower energizer, nourishing kidney-yin, qi depression to blood stasis etc.But because of the primary disease course of disease is generally longer, easily recurrence, refractory more, so the more unstable medication effects of the big pattern of syndrome of syndrome variation are not fairly obvious, also some effect of drugs still is passable certainly, but treatment time is oversize, have in addition reach 2～3 years.Make patient can't adhere to eating for a long time.

The object of the invention also is to adopt dialectical opinion to control, with former typing, the hepatic and renal YIN deficiency, damp invasion of lower energizer, deficiency of spleen-YANG and kidneyYANG, various dialectical executing such as qi depression to blood stasis controlled the comprehensive various one that is.The specimen of knowing the secondary from the primary is the foundation of legislation prescription, and to mend the congenital foundation, it is main that kidney tonifying is superintended and directed by force, the spleen of the beneficial day after tomorrow, one opens source of generating QI and blood, improves organism quality, one relies the QI and blood abundanceization, the living marrow of essence is mended congenital, and the basis that depends on that an eliminating dampness by diuresis destroys heat is auxilliary, the softening the hard mass stasis of blood alive, the detoxifcation heat clearing away is with scorchingly hot agglutinating pathology of the expectorant stasis of blood and pathological metabolism product, improve the QI and blood circulation, the recovery organization function, thus make generally i.e. recovery from illness in three courses of treatment of prostatosis.

The present invention is achieved in that Squama Manis 1-6g, Radix Panacis Quinquefolii 1-5g, Radix Astragali 2-8g, the mountain is in meat 1-6g, fructus lycii 2-6g, Colla cornus cervi 1-5g, Spora Lygodii 2-6g, Radix Notoginseng 1-4g, Medulla Tetrapanacis 2-6g, field Herba Cistanches 2-6g, Rhizoma Coptidis 1-5g, Rhizoma Alismatis 2-6g, Polyporus 1-6g, Solenognathus 1-5g, Cornu Saigae Tataricae 1-3g, Colla Plastri Testudinis 2-5g, Dendrobium nobile 2-5g, Cortex Phellodendri 2-7g.

The most preferred embodiment of above-mentioned medicine is:

Squama Manis 3g, Radix Panacis Quinquefolii 3g, Radix Astragali 4g, the mountain is in meat 3g, fructus lycii 5g, Colla cornus cervi 3g, Spora Lygodii 4g, Radix Notoginseng 2g, Medulla Tetrapanacis 3g, field Herba Cistanches 5g, Rhizoma Coptidis 2g, Rhizoma Alismatis 3g, Polyporus 3g, Solenognathus 2g, Cornu Saigae Tataricae 1.5g, Colla Plastri Testudinis 3g, Dendrobium nobile 4g, Cortex Phellodendri 3g.

The concocting method of above-mentioned medicine is: selected first-class high-quality medicine removes impurity, non-medicine part branch, strictly observe ancient doctor's concocting method, add modern science sterilization method, Squama Manis Oleum sesami burned, the stir-fry of Rhizoma Coptidis vinegar, the stir-fry of Cortex Phellodendri salt, Radix Panacis Quinquefolii, Radix Astragali, mountain are in medicines such as meat, fructus lycii, Colla cornus cervi, Colla Plastri Testudinis, Radix Notoginseng, Medulla Tetrapanacis, field Herba Cistanches, Rhizoma Alismatis, pulverizing is through 120 mesh sieves behind the roasting oven dry of the electricity detoxification, wear into water and fly powder, the cold boiled water of impalpable powder, make granule with modernized pharmacy machine, drying strict sterilization in 48 hours through ultraviolet radiation.Every 100g adorns one bottle, and it is standby that wax seal forms vacuum.

Good effect of the present invention is to take in altogether in 3 years year April of in April, 1993 to 1996 to observe chronic prostate patient 500 examples, meets and observes claimer's 436 examples, and this 436 example is all observed in outpatient service, minimum 21 years old of age was 65 to the maximum, wherein 21-29 year 50 examples, 30-39 year 132 examples, 40-49 year 112 examples, 50-59 year 98 examples, 44 examples more than 60 years old, the shortest person of the course of disease 8 months is the longest to be 25 years, wherein 1 year with interior person's 94 examples, 1-4 person's 186 examples, 5-9 66 examples, 10-19 person's 19 examples, 42 examples more than 20 years.Occupation distributes, cadre's 204 examples, workman's 156 examples, other 76 examples.

Clinical effectiveness, 436 routine patients, through three course of therapy, 86 examples of fully recovering account for 19.7%, and produce effects 250 examples account for 57.33%, and effective 62 examples account for 14.2%, total effective rate 91.2%.

Goods of the present invention are to treatment prostatitis 78 routine follow-up Report.

Follow-up results:

1. 52 example recovery from illness patients and 26 routine produce effects patients are carried out following up a case by regular visits to later in 1 year.

2. after following up a case by regular visits to end, former recovery from illness patient 52 people, 6 example recurrences, relapse rate is 11.53%, and former clinical produce effects patient 23 people adhere to obeying goods of the present invention again, reaches the clinical cure standard in three months, 3 routine withdrawals are recurred because of upper respiratory tract infection, and total relapse rate is 11.5%.

3. cause of recurrence is: infect, libido does not save, and drinks the pungent stimulation food of surfeit, the easiest recurrence that causes of especially drinking.

Follow up a case by regular visits to way: this city: combine with phone and visit to the parents of schoolchildren or young workers.Other places: visit with the communication letter.

With evaluation criteria: doctor trained in Western medicine is a foundation with Xie Wenying " spermology " (1991.P33.2 of Science and Technology of Shanghai publishing house).The traditional Chinese medical science: first volume of " the new Chinese medicine clinical trial guideline " formulated with Ministry of Public Health) (version in 1993) is foundation.

Chronic prostatitis belongs to the traditional Chinese medical science " stranguria with turbid discharge " categories such as " excessive in vain ", and the present invention is by deficiency and excess two guiding principle expectorant, and is wet, heat, the stasis of blood four classes are divided and are suffered from a deficiency of the kidney admittedly, deficiency-weakness of spleen-QI, blood-stasis internal-depression, damp invasion of lower energizer, five types such as simulataneous insufficiency and excessive, on the overall prescription with nourishing the liver and kidney, invigorating the spleen and replenishing QI, stasis and resolving masses alive, clearing heat and freeing strangury is a method, table is the case of several situations of treatment below:

The hard void of syndrome situation of change treatment table admittedly 51 example recoveries from illness, 8 produce effects, 29 effective 7 invalid 7 efficient 86% deficiency-weakness of spleen-QI, 62 example recoveries from illness, 9 produce effects, 25 effective 22 invalid 6 efficient 90.3% blood-stasis internal-depression, 80 example recoveries from illness, 21 produce effects, 30 effective 26 invalid 3 efficient 96.25% damp invasion of lower energizer, 35 example recoveries from illness, 25 produce effects, 7 effective 3 invalid 0 efficient 100% simulataneous insufficiency and excessive 208 example recoveries from illness, 46 produce effects 21 effective 40 invalid 1 efficient 99.5% amount to 436 examples

From the clinical efficacy that syndrome changes, prostatosis is based on simulataneous insufficiency and excessive, and is too heavy if spleen or suffer from a deficiency of the kidney resembles, the relatively poor only 86-90% of clinical efficacy, deficiency and excess is held concurrently mutually, and curative effect is better, can reach 99.5%, total effective percentage illustrates that up to 96.1% the present invention is more satisfactory to improving clinical symptoms.

The urine pus cell changes (327 example)

Pus cell

＜+ + ++ +++ ++++

Treat preceding 0 111 99 72 45

Treated back 30 days 54 90 102 54 27

60 days 54 120 90 45 18

90 days 66 183 36 30 12

Find out that from last table the present invention is ideal to eliminating pus cell.

Obey formulation method of the present invention:

Watered pill every day three times, each 6 gram boiled water take.

30 days is a course of treatment, finishes back Comprehensive Assessment curative effect three courses of treatment.

Evaluation criteria:

Recovery from illness: clinical symptom disappearance, check that every index is normal

Produce effects: clinical symptom disappearance, normal or every index is abnormal fully to check every index, but not complete obiteration of clinical symptoms

Effectively: clinical symptom relief, check every index improvement

Invalid: clinical symptoms does not alleviate or increases the weight of, and checks that every index is not improved or clinical symptoms increases the weight of

Case one: Zhang, man, 25 years old, workman.Because of young masturbation, when urinating penis twinge is gradually arranged, mucus is arranged behind the urine, went certain hospital's urology department to go to a doctor before 10 months, be diagnosed as chronic prostatitis.Existing disease: left testicular pain, lower abdomen expands, and urethral orifice has secretions, soreness of waist Mental fatigue, sleep is easily frightened, and the anus touch checks that right lobe of prostate increases, and tenderness is arranged, and there is dim spot on the body of the tongue limit, and the fine and smooth card of gland belongs to, the spleen kidney deficiency, turbid stasis of blood retardance, the hole key is obstructed.Prostatic fluid routine before the medication, pyocyte ++ lecithin ++, with prescription of the present invention month, testicular pain obviously alleviated behind the medicine, only gently expanded sometimes, dull pain is arranged during extruding, lower abdomen do to expand and to alleviate, and prostate anus palpation does not have tenderness, prostatic fluid: pyocyte a little, lecithin ++, continue to obey two courses of treatment.Advise few food pungent, give up the masturbation bad habit, note health.Visit half a year, all are normal.

This routine patient is relevant with masturbation, as " dialectical record " institute cloud: " people has the urine turbid person that bleeds, as the juice of half water from washing rice, this disease about go into that room inconvenience is freely let out and to bear smart person in the majority " so after recovering, relinquish bad habits most important.

Case two, poplar, man, 45 years old, cadre.First visit on October 4 in 1993.Expand plug dull pain 2 years of sick premature ejaculation of patient and perineal position is surplus, and soreness of waist shin is soft, dizzy cardiopalmus, fatiguability, moving and sweating, the emotion gloom, lower abdomen is latent to expand, frequent micturition, urgent micturition, the urine yellow skin is turbid, the heeltap not to the utmost, stool firmly the time urethral orifice have milky or faint yellow mucus to discharge.Examination of prostatic fluid: 16 high power fields of leukocyte.Lecithin reduces＜30%.And routine examination: erythrocyte a little, leukocyte ++.The anus touch: the body of gland size is normal, hard slightly, touches obviously painful.Be diagnosed as chronic prostatitis.Patient's self-induction soreness of waist shin is soft, yellowish or reddish urine, and difficulty in micturition, sagging distention in the smaller abdomen, spiritlessness and weakness, red tongue, yellow and thin fur, the thin stringy and rapid pulse of gland, card is lost by kidney spleen two, contains in damp and hot, and is strongly fragrant and the fire-transformation impairment of YIN is accumulate the long-pending part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, so that stranguria with turbid discharge.With month sx of prescription of the present invention, use one month again, brace up, it is normal to urinate, and dribbling urination removes, and prostatic fluid routine and microscopy are all normal, the anus touch, the gland software does not have and touches a tender spot.Light red tongue, the white and thin fur moderate pulse, the clothes that continue were consolidated curative effect in one month.

Claims (3)

1, a kind of medicine for the treatment of prostatosis is characterized in that: it is by Squama Manis 1-6g, Radix Panacis Quinquefolii 1-5g, Radix Astragali 2-8g, the mountain is in meat 1-6g, fructus lycii 2-6g, Colla cornus cervi 1-5g, Spora Lygodii 2-6g, Radix Notoginseng 1-4g, Medulla Tetrapanacis 2-6g, field Herba Cistanches 2-6g, Rhizoma Coptidis 1-5g, Rhizoma Alismatis 2-6g, Polyporus 1-6g, Solenognathus 1-5g, Cornu Saigae Tataricae 1-3g, Colla Plastri Testudinis 2-5g, Dendrobium nobile 2-5g, Cortex Phellodendri 2-7g forms.

2, a kind of medicine for the treatment of prostatosis is characterized in that:

Squama Manis 3g, Radix Panacis Quinquefolii 3g, Radix Astragali 4g, the mountain is in meat 3g, fructus lycii 5g, Colla cornus cervi 3g, Spora Lygodii 4g, Radix Notoginseng 2g, Medulla Tetrapanacis 3g, field Herba Cistanches 5g, Rhizoma Coptidis 2g, Rhizoma Alismatis 3g, Polyporus 3g, Solenognathus 2g, Cornu Saigae Tataricae 1.5g, Colla Plastri Testudinis 3g, Dendrobium nobile 4g, Cortex Phellodendri 3g.

3, manufacture method according to claim 1 or 2 medicines, it is characterized in that: selected first-class high-quality medicine, remove impurity, the non-medicine part branch, strictly observe ancient doctor's concocting method, add the modern science sterilization method: Squama Manis Oleum sesami burned, Rhizoma Coptidis vinegar is fried, Cortex Phellodendri salt is fried, Radix Panacis Quinquefolii, Radix Astragali, the mountain is in meat, fructus lycii, Colla cornus cervi, Radix Notoginseng, Medulla Tetrapanacis, the field Herba Cistanches, Rhizoma Alismatis, Spora Lygodii, Polyporus, Solenognathus, Cornu Saigae Tataricae, Colla Plastri Testudinis, gold hook Herba Dendrobii, behind the roasting oven dry of the electricity detoxification, pulverizing, through 120 mesh sieves, wear into water and fly powder, the cold boiled water of impalpable powder is made granule with modernized pharmacy machine, drying in 48 hours through ultraviolet radiation, strict sterilization, every 100g adorns one bottle, and it is standby that wax seal forms vacuum.