CN1194744C - Medicine for treating skin chap, and preparing method thereof - Google Patents

Abstract

The present invention discloses novel medicine for treating skin chaps, which is formed by proportionally compounding raw materials such as common clubmoss herb, garden balsam stem, peach kernel, safflower, red peony root, chuanxiong rhizome, Chinese angelica, radix dipsaci from Sichuan of China, psoralea fruit, suberect spatholobus stem, achyranthes, kudzuvine root, cassia twig, dahurian angelica, asarum herb, ephedra herb, drug sweetflag rhizome, polygala root, lucid ganoderma, caterpillar fungus, borneol and mirabilite. The medicine is prepared into powder preparations by treatments such as grinding, screening, processing in groups, uniformly blending, disinfection and sterilization, etc., according to different characteristics of each kind of the traditional Chinese medicine. The formulation and the production method of the present invention are convenient and unique. The therapeutic effect of the medicine is obvious.

Description

The medicine and the preparation method of treatment chapped skin

Technical field

The present invention relates to a kind of medicine for the treatment of chapped skin.Being specifically related to the Chinese herbal medicine is the Chinese patent medicine of feedstock production, the invention still further relates to the preparation method of this medicine.

Background technology

Rhagadia manus et pedis is comparatively common a kind of dermatosis in winter, is more common in old people and women, because of often being subjected to the stimulation of mechanicalness or chemical substance, winter climate cold in addition, subcutaneous sweat gland secretion reduces, xerosis cutis, skin keratin thickens and follows the string, so very easily chap when brothers move.Show as thickening of finger, heel, sufficient edge, and crack occurs along the dermatoglyph direction, its depth, different in size, the severe patient crack is with hemorrhage and tangible pain.

Skin is the human body largest organ, accounts for 16% of TBW, and area is 1.5 square metres (adults), also with abundant nerve, blood vessel, lymphoid tissue and skin appendages etc.

The main cause of chapped skin is that wind and cold blood is dry, due to skin mistake profit and cell tissue are impaired.Both at home and abroad to the treatment of chapped skin, run into following problem at present:

1, it is low to utilize carbamide, soft petroleum ointment and rubber plaster to wipe curative effect outward, and treatment cycle is long, and using for a long time has dependency to medicine, and drug withdrawal is promptly recurred.Especially big to the crack, with hemorrhage and pain patients, curative effect is more not obvious, causes difficulty in walking, makes troubles for work, life.Often use oil ointment also can pollute footgear.

2, simple hot-water soak, but fatigue alleviating only can not reach the effect of treatment.

3, utilize the sufficient lotion of bubble, because of not containing the absorbable nutrient substance of skin in the medicament, and composition is simple, can not treat chapped skin.

Summary of the invention

The technical issues that need to address of the present invention are to provide a kind of makes the nutrition in the medicine enter human body through skin by the bathing form, promotes that skin effectively absorbs, thereby improves the soak type bathing agent of the treatment chapped skin of tissue repair function.

Another technical problem that the present invention need solve provides the preparation method of this chapped skin soak type bathing agent.

Solution of the present invention is based on motherland's traditional medicine to chapped skin mechanism understanding and Therapeutic Principle, with reference to the modern pharmacological research achievement, from motherland's medical treasure-house, filter out have blood circulation promoting and blood stasis dispelling, remove old tissue regeneration promoting, relieving spasm to stop pain, reinforcement tissue metabolism, repair the soak type bathing agent that the multiple pure natural Chinese herbal medicine of damaging cells is made.By the theory of Chinese medical science prescription, skim the cream off milk, make it have the effect that improves human internal environment, raising tissue repair function.

Medicine of the present invention is made (consumption is a weight portion) by following component:

Herba Lycopodii 10-40 Herba speranskiae tuberculatae 10-40 Semen Persicae 2-6 Flos Carthami 2-6

Radix Paeoniae Rubra 2-6 Rhizoma Chuanxiong 4-10 Radix Angelicae Sinensis 3-10 Radix Dipsaci 4-10

Fructus Psoraleae 3-10 Caulis Spatholobi 3-10 Radix Achyranthis Bidentatae 4-12 Radix Puerariae 6-12

Ramulus Cinnamomi 3-8 Radix Angelicae Dahuricae 3-10 Herba Asari 2-6 Herba Ephedrae 4-8

Rhizoma Acori Graminei 3-8 Radix Polygalae 3-8 Ganoderma 2-8 Cordyceps 1-4

Borneolum Syntheticum 3-10 Natrii Sulfas 5-10

Formula optimization weight (part) ratio range of preparation medicine of the present invention is:

Herba Lycopodii 10-30 Herba speranskiae tuberculatae 10-30 Semen Persicae 3-6 Flos Carthami 4-6

Radix Paeoniae Rubra 2-4 Rhizoma Chuanxiong 4-8 Radix Angelicae Sinensis 4-8 Radix Dipsaci 4-8

Fructus Psoraleae 4-7 Caulis Spatholobi 4-8 Radix Achyranthis Bidentatae 4-8 Radix Puerariae 6-10

Ramulus Cinnamomi 3-6 Radix Angelicae Dahuricae 4-8 Herba Asari 3-6 Herba Ephedrae 4-6

Rhizoma Acori Graminei 4-7 Radix Polygalae 4-6 Ganoderma 2-6 Cordyceps 1-3

Borneolum Syntheticum 4-8 Natrii Sulfas 6-8

The optimum weight of medicine of the present invention (part) proportioning is:

Herba Lycopodii 10 Herba speranskiae tuberculataes 10 Semen Persicaes 4 Flos Carthamis 4

Radix Paeoniae Rubra 4 Rhizoma Chuanxiongs 4 Radix Angelicae Sinensis 4 Radix Dipsaci 6

Fructus Psoraleae 6 Caulis Spatholobis 8 Radix Achyranthis Bidentataes 6 Radix Puerariaes 8

Ramulus Cinnamomi 6 Radixs Angelicae Dahuricae 6 Herba Asaris 4 Herba Ephedraes 4

Rhizoma Acori Graminei 4 Radix Polygalaes 4 Ganodermas 2 Cordycepses 1

Borneolum Syntheticum 8 Natrii Sulfas 6

Above-mentioned each component is made medicine production method of the present invention is:

1, earlier will above-mentioned each the component single medicinal material except that Natrii Sulfas, Borneolum Syntheticum, Radix Achyranthis Bidentatae, Semen Persicae puts into beating crusher and smash, form coarse powder.

2,, the coarse powder of above-mentioned each component and Natrii Sulfas, Borneolum Syntheticum, Radix Achyranthis Bidentatae, Semen Persicae are divided into 4 groups by following requirement for mix homogeneously and prevent volatilization:

(1) Herba Lycopodii Herba speranskiae tuberculatae made from peach kernel, safflower Radix Paeoniae Rubra

(2) szechuan lovage rhizome-angelica Radix Dipsaci Fructus Psoraleae Natrii Sulfas Borneolum Syntheticum

(3) Caulis Spatholobi Radix Achyranthis Bidentatae Radix Puerariae ganoderma lucidum cordyceps sinensis

(4) Ramulus Cinnamomi Radix Angelicae Dahuricae Herba Asari Herba Ephedrae Rhizoma Acori Graminei Radix Polygalae

3, the above coarse powder of respectively organizing is ground to form 150 order fine powders respectively, remove waste residue through screening.Again (3) group fine powder is put into the hyperfine abrasive machine and grind to form 400 order micropowders, and every group of medicine deposited 72 hours in shady and cool dry place sealing.

4, sealed the medicine of depositing with above 4 groups and put into the blender uniform mixing, through-15 ℃ of cold sterilization sterilizations 2 hours.

5, will more than fine powder after disinfecting, be packaged in every pouch 20 grams that sealing can obtain the shape preparation that looses in the plastic bag.

An important feature of the present invention is to contain rich nutrient substances---chitosan in the medicament, and it is the derivant of animal fiber, is the nutrient of needed by human, called after Chitosan in the world, and China is called chitin.It is that chemical bond is the polysaccharide body that a β-1-4 chain connects, it is alkaline matter, in human body, can be broken down into episome, not need carrier and can enter each organs and tissues of human body, comprise the almost unapproachable collagenic connective tissue barrier of blood brain barrier, placental barrier and other medicines.But injured cell is repaired in the differentiation of chitosan inducing immune cells, and it directly acts on human immunity maincenter organ, hematopoietic stem cell, and the hydropic degeneration of pair cell, fibrosis, variation etc. have direct effect.

In addition, also contain trace element magnesium, germanium, calcium, selenium, phosphorus, sodium, ferrum, chromium, manganese, copper, zinc, potassium and nitrogen, carbon, iodine etc. in the chapped skin soak type bathing agent of the present invention, they can promote human body skin metabolism desired nutritional.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, to select natural plant for use be raw material in the present invention, and each component all meets national pharmaceutical control law regulation.Utilize the comprehensive function treatment chapped skin of the Chinese herbal medicine of respectively distinguishing the flavor of, nontoxic to human body.

2, medicine of the present invention need not decoct, and is easy to use, meets the national health law regulation.

3, this medicament is as soak type bathing agent, and very easily water-soluble, by whole body immersion skin, the abundant nutrition that can fully absorb the drug and contain is effectively treated chapped skin.But also can remedy independent use medicine or steep sufficient lotion and the limited weakness of difficult absorption, curative effect that exists, improving the tissue repair function, curative effect is obvious.

4, medicament of the present invention can replace the traditional therapy of having used at present, and production cost is low.

Drug use of the present invention is easy, and the patient with this medicament 20 grams (a bag), is dissolved in 120 liters at every turn, 40 ℃ of bubbly waters are bathed and got final product in 30 minutes.

For showing the therapeutic effect of bathing agent of the present invention to chapped skin, the present invention is through 156 examples (wherein, man 36, woman 120; 30-49 year 47 people, 50-70 year 109 people) system's clinical observation, its curative effect sees Table 2.

Table 2 uses bathing agent clinical observation result table of the present invention

Treatment time (week)	1	2	4
				Healing number (people)	79	53	24

In addition, use bathing agent of the present invention, can make the update cycle of human body skin foreshorten to 13-28 days from 41-75 days.

The specific embodiment

Take by weighing raw material (kilogram) by following proportioning

Herba Lycopodii 20 Herba speranskiae tuberculataes 20 Semen Persicaes 8 Flos Carthamis 8

Radix Paeoniae Rubra 8 Rhizoma Chuanxiongs 8 Radix Angelicae Sinensis 8 Radix Dipsaci 12

Fructus Psoraleae 12 Caulis Spatholobis 16 Radix Achyranthis Bidentataes 12 Radix Puerariaes 16

Ramulus Cinnamomi 12 Radixs Angelicae Dahuricae 12 Herba Asaris 8 Herba Ephedraes 8

Rhizoma Acori Graminei 8 Radix Polygalaes 8 Ganodermas 4 Cordycepses 2

Borneolum Syntheticum 16 Natrii Sulfas 12

Production method is as follows:

Get above-mentioned each component single medicinal material except that Natrii Sulfas, Borneolum Syntheticum, Radix Achyranthis Bidentatae, Semen Persicae earlier and put into beating crusher and smash, form coarse powder; Again the coarse powder of above-mentioned each component and Natrii Sulfas, Borneolum Syntheticum, Radix Achyranthis Bidentatae, Semen Persicae are divided into 4 groups by following requirement:

(1) Herba Lycopodii Herba speranskiae tuberculatae made from peach kernel, safflower Radix Paeoniae Rubra

(2) szechuan lovage rhizome-angelica Radix Dipsaci Fructus Psoraleae Natrii Sulfas Borneolum Syntheticum

(3) Caulis Spatholobi Radix Achyranthis Bidentatae Radix Puerariae ganoderma lucidum cordyceps sinensis

(4) Ramulus Cinnamomi Radix Angelicae Dahuricae Herba Asari Herba Ephedrae Rhizoma Acori Graminei Radix Polygalae

The above coarse powder of respectively organizing is all ground to form 150 order fine powders, remove waste residue through screening.Again (3) group fine powder is put into the hyperfine abrasive machine and grind to form 400 order micropowders, and every group of medicine deposited 72 hours in shady and cool dry place sealing; Sealed the medicine of depositing with above 4 groups then and put into the blender uniform mixing, through-15 ℃ of cold sterilization sterilizations 2 hours; At last more than fine powder after disinfecting, be packaged in the plastic bag sealing with every pouch 20 grams and can obtain the present invention's shape preparation that looses.

Claims (5)

1, a kind of medicine for the treatment of the chapped skin disease is characterized in that it is the medicament of being made by the following weight proportion raw material

Herba Lycopodii 10-40 Herba speranskiae tuberculatae 10-40 Semen Persicae 2-6 Flos Carthami 2-6

Radix Paeoniae Rubra 2-6 Rhizoma Chuanxiong 4-10 Radix Angelicae Sinensis 3-10 Radix Dipsaci 4-10

Fructus Psoraleae 3-10 Caulis Spatholobi 3-10 Radix Achyranthis Bidentatae 4-12 Radix Puerariae 6-12

Ramulus Cinnamomi 3-8 Radix Angelicae Dahuricae 3-10 Herba Asari 2-6 Herba Ephedrae 4-8

Rhizoma Acori Graminei 3-8 Radix Polygalae 3-8 Ganoderma 2-8 Cordyceps 1-4

Borneolum Syntheticum 3-10 Natrii Sulfas 5-10.

2, the medicine of treatment chapped skin disease according to claim 1, wherein the weight proportion of each raw material is

Herba Lycopodii 10-30 Herba speranskiae tuberculatae 10-30 Semen Persicae 3-6 Flos Carthami 4-6

Radix Paeoniae Rubra 2-4 Rhizoma Chuanxiong 4-8 Radix Angelicae Sinensis 4-8 Radix Dipsaci 4-8

Fructus Psoraleae 4-7 Caulis Spatholobi 4-8 Radix Achyranthis Bidentatae 4-8 Radix Puerariae 6-10

Ramulus Cinnamomi 3-6 Radix Angelicae Dahuricae 4-8 Herba Asari 3-6 Herba Ephedrae 4-6

Rhizoma Acori Graminei 4-7 Radix Polygalae 4-6 Ganoderma 2-6 Cordyceps 1-3

Borneolum Syntheticum 4-8 Natrii Sulfas 6-8.

3, the medicine of treatment chapped skin disease according to claim 1, wherein the weight proportion of each raw material is

Herba Lycopodii 10 Herba speranskiae tuberculataes 10 Semen Persicaes 4 Flos Carthamis 4

Radix Paeoniae Rubra 4 Rhizoma Chuanxiongs 4 Radix Angelicae Sinensis 4 Radix Dipsaci 6

Fructus Psoraleae 6 Caulis Spatholobis 8 Radix Achyranthis Bidentataes 6 Radix Puerariaes 8

Ramulus Cinnamomi 6 Radixs Angelicae Dahuricae 6 Herba Asaris 4 Herba Ephedraes 4

Rhizoma Acori Graminei 4 Radix Polygalaes 4 Ganodermas 2 Cordycepses 1

Borneolum Syntheticum 8 Natrii Sulfas 6.

4,, it is characterized in that said medicament is a powder according to the medicine of claim 1 or 2 or 3 described treatment chapped skin diseases.

5, the preparation method of the medicine of the described treatment chapped skin of claim 4 disease is characterized in that getting earlier above-mentioned each component single medicinal material except that Natrii Sulfas, Borneolum Syntheticum, Radix Achyranthis Bidentatae, Semen Persicae and puts into beating crusher and smash, and forms coarse powder; Again the coarse powder of above-mentioned each component and Natrii Sulfas, Borneolum Syntheticum, Radix Achyranthis Bidentatae, Semen Persicae are divided into 4 groups by following requirement:

(1) Herba Lycopodii Herba speranskiae tuberculatae made from peach kernel, safflower Radix Paeoniae Rubra

(2) szechuan lovage rhizome-angelica Radix Dipsaci Fructus Psoraleae Natrii Sulfas Borneolum Syntheticum

(3) Caulis Spatholobi Radix Achyranthis Bidentatae Radix Puerariae ganoderma lucidum cordyceps sinensis

(4) Ramulus Cinnamomi Radix Angelicae Dahuricae Herba Asari Herba Ephedrae Rhizoma Acori Graminei Radix Polygalae

The above coarse powder of respectively organizing is all ground to form 150 order fine powders, remove waste residue through screening.Again (3) group fine powder is put into the hyperfine abrasive machine and grind to form 400 order micropowders, and every group of medicine deposited 72 hours in shady and cool dry place sealing; Sealed the medicine of depositing with above 4 groups then and put into the blender uniform mixing, through-15 ℃ of cold sterilization sterilizations 2 hours; At last more than fine powder after disinfecting, be packaged in the plastic bag sealing with every pouch 20 grams and can obtain the present invention's shape preparation that looses.