CN1194673C - Anti-Virus arosol inhalation medicine liquid - Google Patents

Abstract

The present invention discloses atomized inhalation physic liquor for atomized inhalation machines, which is prepared in a mode that a disinfectant which is capable of directly killing viruses and has low toxicity and irritation for human bodies is diluted to a concentration, and the concentration has less damage to inner surface mucous membranes of people's respiratory systems and has effects on viruses. After the atomized inhalation physic liquor is atomized into small droplets to be sucked, pathogenic viruses on inner surface mucous membranes of respiratory systems can be effectively inhibited and killed, and the atomized inhalation physic liquor penetrates in the microcirculatory blood of lungs; accordingly, virus activity and toxicity are reduced in local blood to make immune cells easily kill one part of viruses in local areas in order that virus identification and immunization of the whole body can be favorably built.

Description

The antiviral atomizing sucks medicinal liquid

The atomizing suction medicinal liquid that technical field the present invention relates to atomize and sucks the machine use.

Background technology does not also have directly for the various diseases that causes of poison due to illness at present, and the oral and flow of infusate of kill virus is used for clinical, reason is that the granule of virus is more much smaller than other pathogen, so drag is big, more difficult killing, the medicine that it can be killed is all very big to the injury of human body.For the available antibiotics of pathogen such as antibacterial it is effectively killed, but antibiotics is invalid to virus.For the virus type disease, be mostly to play certain therapeutical effect indirectly by improving the medicine of body immunity.The medicinal liquid that present atomizing sucks is by the machine that atomizing sucks medical liquid atomizing to be become minimum droplet, breathes then to reach therapeutic purposes after sucking.Wherein be used for diluting human lung's trachea, intrabronchial sputum more, make the too dried condensed sticking expectorant that is difficult for discharging after dilution, be convenient to discharge, also there is the atomizing of the antibiotics of use to suck and plays certain local antiinflammation, but viral respiratory system disease is not had direct therapeutical effect.

Thereby summary of the invention the objective of the invention is to provide a kind of directly inhibition and kill virus treatment due to illness the disease that causes of poison be used to the medicinal liquid that atomizes and suck.

The medicine of known directly kill virus is all very big to the human injury at present, can not be used for oral and transfusion, just is used for disinfectant and uses.The characteristics of human respiratory are that it has and the extraneous inner surface mucosa that carries out gas exchange, and it is very limited sucking by atomizing that the medicinal liquid that arrives the inner surface mucosa is absorbed by the body.The repair ability of human body mucosal epithelium cell is generally all very strong, choose the suitable direct kill virus of energy to people's toxicity and the zest little disinfectant of all trying one's best, and being diluted to the most appropriate concentration is prepared, be to accomplish little prerequisite is tried one's best in assurance to respiratory system inner surface mucosa injury under, to reach directly killing and inhibitory action to virus.Do although it is so and can not directly the virus of inside of human body tissue be killed, but can directly kill, suppress the virus on the respiratory system inner surface mucosa, and the performance of the first symptoms of respiratory system disease just in time is on the pathological changes of these mucous membrane surfaces, so symptom is eased.On the other hand, lungs are internal organs of blood oxygen metabolism, and its blood microcirculation is very abundant.The medicinal liquid that atomizing sucks enters blood after more easily being absorbed by surface mucous.Even use the very low drug level can not kill virus, but as long as it can suppress and reduce the activity and the toxicity of sub-fraction virus in local zonule (pulmonary blood microcirculation zone), just can help immunocyte in the blood and more easily this fraction virus of this regional area be killed and engulfed, set up identification and immunity virus thereby help whole body.From immune angle,, just shortened the course of disease if can shorten time of immunologic process like this to the poison of newly catching an illness.For long-term incurable chronic disease after due to illness poison infects, as long as these Causative viruss can be with blood circulation to the microcirculatory regional area of pulmonary, because these viral sub-fractions are suppressed, just might activate the kill ability of the interior immunocyte of blood again to these viruses, form immunity, realize therapeutical effect.Analyze thus, in medication, drug level can be very low.For viral respiratory system disease critically ill patient; because the infection of virus, mucous the oozing out of inflammatory of causing the mucosa interior tissue covered mucous membrane surface; at certain phase, to a certain extent, also played the effect of protection for the stimulation of medicine and damage.From the characteristics of atomizing suction machine, it becomes minimum droplet by ultrasound wave with medical liquid atomizing, can be covered in the inner surface of respiratory system after the suction equably, so actual suction volume seldom.In the selection of medication, the disinfectant that selection toxicity is low, zest is little, the little virus function that goes out simultaneously of damage is strong is with regard to particular importance.

The various disinfectant that the specific embodiment contains effective chlorine all have the wide spectrum killing action to virus, and general toxicity is all lower, as long as make concentration dilution arrive suitable level, can be used for preparing atomizing and suck medicinal liquid.

" Venus disinfectant solution " that China produces is a kind of chlorine-containing disinfectant, has the very strong virus function that goes out, health and epidemic prevention department through the whole nation is detected, it can be with the most difficult hepatitis B virus of killing 100% deactivation in one minute, even have only at effective chlorine density under the concentration situation of 5/1000000ths (5PP), still have very strong disinfective action.Its disinfectant solution that is used for the sterilization of instruments type detects through acute toxicity testing, and toxicity is also lower than Sal.The main disinfection composition of this disinfectant solution is the hypochlorite ion.Because of this disinfectant solution is stronger alkalescence, suppressed unsettled hypochlorous generation, also just suppressed simultaneously the generation of elemental oxygen, the prescription effect of its uniqueness in addition, make that its disinfectant solution stability that is used for sterilization of instruments is extremely strong, so that depositing more than 8 years after the time, effective chlorine density does not descend yet.Easily decompose the disinfectant that discharges elemental oxygen with other and compare, its injury to human body just may be relative smaller with stimulation.According to above characteristics, use " Venus disinfectant solution " preparation atomizing inhalation liquor ratio safer, effective.

My toxicity acute conjunctivitis that suffers from a disease in 1993, be commonly called as pink eye disease, with various antibiotics medicament for the eyes all ineffective, the state of an illness constantly increases the weight of, so I with sterilization of instruments type " Venus disinfectant solution " thin up 200 times, eye drip then, every has dripped one, feel that very soon misery alleviates greatly, basic recovery from illness in second day.It is more much better than than " the Venus disinfectant solution " of other sterilization type because of the stability of concentration of the effective chlorine of considering it using sterilization of instruments type " Venus disinfectant solution ", so the effective chlorine density of preparation liquid is also grasped with regard to relatively good control.The effective chlorine density of sterilization of instruments type " Venus disinfectant solution " is 0.6%-1% (6000PP to 10000PP), thus the effective chlorine density of my eye drop 50/30/1000000ths to 1000000ths (30PP---50PP) between.I used 90 times of eye drips of sterilization of instruments type " Venus disinfectant solution " dilution again afterwards, still can bear, and effective chlorine density is between 110/67/1000000ths to 1000000ths (67PP-110PP).

Nineteen ninety-five, I was after having suffered from flu, splash into nasal cavity with behind 200 times of sterilization of instruments type " Venus disinfectant solution " thin ups, the state of an illness alleviates very soon, the course of disease shortens, change 400 times of thin ups later on again into, effective chlorine density is between 25/15/1000000ths to 1000000ths (15PP-25PP), and effect is also good.My father (time 85 years old year) when catching a cold, also gave him the collunarium chamber with the diluent that adds 400 times in water afterwards, and effect is also good, but he is longer a period of time after throwing off a cold, and nose is very dry, and this illustrates the old people, this concentration is some height still, and the blanking time of a medicine should be more longer.

I used 600 times of sterilization of instruments type " Venus disinfectant solution " thin ups in 2003, effective chlorine density is between 17/10ths/1000000ths to 1,000,000 (10PP-17PP), sucked one minute with the atomizing of atomizing inhalation machine, the very fast disappearance of the symptom that has some inkling of a cold, but second day one side nasal cavity is very dried, dryness in the nasal cavity transference cure after three days, illustrate that atomizing is drawn into the easier drying that causes of pulmonary, this point and eyes have very big difference, and are because respiratory system is the organ of gas exchange circulation, very easily dry.On the other hand, since the people is had significant reaction, illustrating more should have effect to virus.The concentration of inferring diluent thus also can further reduce, and to alleviate the damage to surface mucous, reduces the chance that causes secondary infection thus.For safety, the atomizing of preparation sucks medicinal liquid, change into 1200 times of sterilization of instruments type " Venus disinfectant solution " thin ups, be effective chlorine density 5/1000000ths to 8/1000000ths (5PP---8PP) between, atomizing sucked one minute, nose was still dry in second day, so according to circumstances, the concentration of effective chlorine also can further reduce to 1,000,000/(1PP).

" Venus disinfectant solution " is except containing time chlorion, also contain other multiple composition, sterilization of instruments type " Venus disinfectant solution " has also added some compositions that may not have the inhibition metal of disinfective action to get rusty for solving the metallic weapon problem of rustiness, do not get rid of the possibility of these compositions to the stimulation injury effect of respiratory tract surface mucous, so under the situation of the concentration that can better control effective chlorine, also can prepare with " Venus disinfectant solution " dilution of other sterilization type.

The composition of " Venus disinfectant solution " energy kill virus is the hypochlorite ion, and therefore atomizing suction medicinal liquid also can directly be prepared with the sodium hypochlorite dilution.

For safety, atomizing sucks medicinal liquid and with normal saline used disinfectant is diluted preparation, effective chlorine density with 1,000,000/to 6/1000000ths (1PP-6PP) for well, according to patient's concrete condition, concentration is improve suitably.

Also will control well the blanking time for atomization inspiration treatment, and the reparation fully of respiratory system inner surface mucosa approximately takes the time more than three days, thus generally once ill should make primary atomization and suck, if necessary, blanking time should more than three days better.

The time that atomizing sucks was controlled in one minute, and it is fixed that the concrete time also will come according to the intensity that the atomizing droplet forms.

After sucking antiviral atomizing suction medicinal liquid, should rationally replenish vitamin A in right amount, be beneficial to the reparation of respiratory system inner surface mucosal epithelium cell.

After sucking antiviral atomizing suction medicinal liquid,, should regularly do atomizing and suck with normal saline for preventing the drying of respiratory system inner surface mucosa.

The Venus disinfectant that embodiment uses is a chlorine-containing disinfectant, and its effective disinfection composition is an effective chlorine, therefore the invention is characterized in that it is formed by the chlorine-containing disinfecting dilution agent, the content of its effective chlorine is 1,000,000/and to 110/1000000ths (1PP-110PP).

Claims (1)

1, a kind of medicinal liquid that is used to atomize and sucks, the machine that sucks by atomizing is atomized into minimum droplet with it, as breathe sucking treatment, it is characterized in that it is formed by the chlorine-containing disinfecting dilution agent then, the content of its effective chlorine is 1,000,000/to 110/1000000ths.