CN1192918A

CN1192918A - Medicinal powder for treatment of hepatitis B and preparation method thereof

Info

Publication number: CN1192918A
Application number: CN97108440A
Authority: CN
Inventors: 戴福华
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-03-12
Filing date: 1997-03-12
Publication date: 1998-09-16

Abstract

The present invention relates to a Chinese proprietary medicine for curing hepatitis B. Said invented Chinese proprietary medicine is made up by using the Chinese medicinal materials of bupleurum root, aconite, cinnamon bark, cinnamon twig, ligustrum fruit, fresh astragalus root, fresh Chinese yam, white peony root, salvia root, isatis root, bushy knotweed root and licorice as raw materials through such processes as crushing, sieving, soaking with ethyl alcohol, steaming, drying, grinding and screening, etc.. Said invented medicine possesses the obvious therapeutic effect for curing chronic active hepatitis and persisting hepatitis, and its clinical test shows that HBsAg negative-changed rate is 39.9%, HBeAg negative-changed rate is 68.6%, anti-HBcIgM negative-changed rate is 80.2%, its curative rate is up to 48.6% and effective rate is up to above 96%.

Description

Medicinal powder for treatment of hepatitis B and preparation method thereof

Hepatitis B is a kind of popular wider infectious disease that is caused by hepatitis virus, cardinal symptom is a loss of appetite, it is weak to feel sick, hepatomegaly companion tenderness, performances such as liver function injury will change slow activity or delay property hepatitis B into as untimely treatment, in case develop into liver cirrhosis, not only bring misery, and therapeutic process is long, the prognosis weak effect to the patient.

Doctor trained in Western medicine is mostly used hepatic, antiviral drugs or immunomodulator etc. to the existing multiple therapy methods of primary disease.Though certain curative effect is arranged, it is low to consolidate rate, and side effect is big, the treatment cost height, thereby people's preference is with treatment by Chinese herbs.

The traditional Chinese medical science thinks that hepatitis B is that damp and hot heresy is touching, and with the passing of time healthy energy is decreased, and by the real void that causes, forms stagnation of liver-QI with deficiency of the spleen, the pathological manifestations of simulataneous insufficiency and excessive such as venation block, and its treatment can be adopted clearing away heat-damp and promoting diuresis, soothing liver and strengthening spleen, liver and kidney tonifying, blood circulation promoting and blood stasis dispelling several different methods.

Chinese medicine bound pair treating hepatitis B has carried out big quantity research in recent years, its Therapeutic Method has been obtained encouraging progress, emerge some treating hepatitis B experts, the prescription and the Chinese patent medicine of many treatment hepatitis B have been developed, as injection, spray, health promoting bag and multiple Chinese patent medicine, some has applied for that patent such as publication number CN 1111142 " powder for treatment of hepatitis B " are a kind of bag core medication of similar 505 primordial qi bags, it is said better curative effect, but its course of treatment is long, it is slow to take effect, being unsuitable for the patient with severe symptoms, also having " a kind of Chinese medicine electuary for the treatment of hepatitis B and preparation method thereof " of publication number CN 1113772, is to be made by 22 flavor Chinese crude drugs such as Radix Ginseng, be with wherein a part of medical material decoction during making, cross Shanghai, concentrate, the leaching of reuse ethanol, and make clear paste behind the concentrating under reduced pressure, all the other pulverizing medicinal materials are to be mixed and made into pill patent medicine with clear paste behind the powder, this manufacture method, must lose the effective ingredient of some flavour of a drug, and formality is numerous and diverse, increases cost.Publication number is that CN 1110588A " YIGAN SAN and preparation method thereof " is the Chinese crude drug compatibility by heat-clearing and toxic substances removing such as Radix Gentianae, Radix Ginseng, replenishing QI to invigorate the spleen in addition, a part of medical material is wherein decocted, crosses simmer down to extractum behind the Shanghai, add all the other medical materials and adjuvant then and make powder, though it is introduced hepatitis B treating effect preferably, do not see widely and use.

The objective of the invention is to select some soothing the liver preferably dissipating depression of QI, benefiting QI for strengthening the superficies, YIN nourishing antipyretic Chinese herbal medicine use simple method, make the low negative conversion rate Chinese patent medicine preferably of holding concurrently of price.

The present invention realizes that with following compatibility prescription and preparation method its compatibility medical material and parts by weight are: Radix Bupleuri 45-55 Radix Aconiti Lateralis Preparata 15-20 Cortex Cinnamomi 12-18 Ramulus Cinnamomi 16-20 Fructus Ligustri Lucidi 18-22 Radix Astragali 25-32 Rhizoma Dioscoreae 16-20 Radix Paeoniae Alba 25-35 Radix Salviae Miltiorrhizae 25-35 Radix Isatidis 30-35 Rhizoma Polygoni Cuspidati 25-35 Radix Glycyrrhizae 8-10

Its preparation method is above-mentioned 12 flavor medical materials of choosing clean dry, by parts by weight compatibility mixing separately, pulverize also all by 60 mesh sieve holes, medicine is put into jerrycan, with adding a cover vexed putting behind the alcohol dampening, and go up the steamer decatize, cold back is taken out medicine and is dried in the sun, fully fine ground again, cross 100 mesh sieve holes, make powder.

According to needs of patients, the powder of making can divide the pouch of packing into, capsule, or adds adjuvant and make granule or tablet.

All medical materials of the present invention are the common Chinese material, wide material sources, and cheap, its preparation method is simple, can keep the intrinsic composition of each medical material.And based on warming YANG, be aided with QI invigorating, protect the moon, removing heat from blood, detoxifcation, has soothing the liver dissipating depression of QI, benefiting QI for strengthening the superficies, YIN nourishing antipyretic function, and taking convenience, lasting medicine, without any side effects, chronic active hepatitis and chronic persistent hepatitis are had significant curative effect, through cc bright hospital of peace, Shaanxi Province hospital of rehabilitation center, ancient city, Xi'an hospital, 429 patient's clinical practices of nine tame hospitals such as the 5th the People's Hospital, Xiangfan City, Hubei, the HBsAg negative conversion rate reaches 39.9%, HBeAg negative conversion rate 68.6%, anti-HBC-IgM negative conversion rate is 80.2%, using the liver function recovery rate after January of the present invention is 92.5%, effective percentage reaches 96% after the medication, and cure rate reaches 48.6%.

Embodiment: used medical material all needs clean dry, weighs following 12 flavor medical materials respectively and carries out compatibility: Radix Bupleuri 55g Radix Aconiti Lateralis Preparata 180g Cortex Cinnamomi 150g Ramulus Cinnamomi 170g Fructus Ligustri Lucidi 200g Radix Astragali 300g Rhizoma Dioscoreae 180g Radix Paeoniae Alba 300g Radix Salviae Miltiorrhizae 300g Radix Isatidis 350g Rhizoma Polygoni Cuspidati 250g Radix Glycyrrhizae 90g.

Pulverize after above-mentioned medical material fully mixed; cross 60 order copper sieve; put into the flat copper container, add a cover vexed the putting one day in back, went up the cage decatize then 1 hour with alcohol dampening; take off container after the cooling; pour out medicine, the back that dries in the sun is fine ground, crosses 100 order copper sieve series and becomes powder; can directly pack into pouch or capsule also can add adjuvant and make granule or tablet.The present invention adopts processing technology such as wine profit, decatize, Exposure to Sunlight, and its purpose is sterilization, activation and ripening, to strengthen medicine invigorating the liver and kidney, the dynamics of YIN nourishing blood.

This medicinal powder for treatment of hepatitis B, oral 1 time is 6 grams, day clothes 2-3 time, three months is a course of treatment:

Claims

1. medicinal powder for treatment of hepatitis B and preparation method thereof, it is characterized in that its compatibility medical material and parts by weight are: Radix Bupleuri 45-55 Radix Aconiti Lateralis Preparata 15-20 is by osmanthus 12-18 Ramulus Cinnamomi 16-20 Fructus Ligustri Lucidi 18-22 Radix Astragali 25-32 Rhizoma Dioscoreae 16-20 Radix Paeoniae Alba 25-35 Radix Salviae Miltiorrhizae 25-35 Radix Isatidis 30-35 Rhizoma Polygoni Cuspidati 25-35 Radix Glycyrrhizae 8-10

2. the preparation method of described medicinal powder for treatment of hepatitis B, it is characterized in that choosing above-mentioned 12 flavor Chinese crude drugs,, pulverize by parts by weight compatibility mixing separately, and all by 60 mesh sieve holes, medicine is put into jerrycan, with adding a cover vexed putting behind the alcohol dampening, and Shanghai Automobile Factory's steamer vapour, cold back is taken out medicine and is dried in the sun, fully fine ground again, cross 100 mesh sieve holes, make powder.

3. according to the preparation method of the described medicinal powder for treatment of hepatitis B of claim 2, it is characterized in that the powder of medicinal powder for treatment of hepatitis B, can divide the pouch of packing into, capsule, or add adjuvant and make granule or tablet.