CN118892446A - 一种含vvn001的眼科组合物 - Google Patents

一种含vvn001的眼科组合物 Download PDF

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Publication number
CN118892446A
CN118892446A CN202310476403.2A CN202310476403A CN118892446A CN 118892446 A CN118892446 A CN 118892446A CN 202310476403 A CN202310476403 A CN 202310476403A CN 118892446 A CN118892446 A CN 118892446A
Authority
CN
China
Prior art keywords
acid
sodium
ophthalmic
ophthalmic composition
citrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202310476403.2A
Other languages
English (en)
Chinese (zh)
Inventor
夏尔宁
韩巧
沈旺
陆阳清沁
高红妍
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Weimu Biotechnology Zhejiang Co ltd
Original Assignee
Weimu Biotechnology Zhejiang Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Weimu Biotechnology Zhejiang Co ltd filed Critical Weimu Biotechnology Zhejiang Co ltd
Priority to CN202310476403.2A priority Critical patent/CN118892446A/zh
Priority to PCT/CN2023/096273 priority patent/WO2024221527A1/zh
Priority to KR1020247022421A priority patent/KR20240159657A/ko
Priority to CA3238321A priority patent/CA3238321A1/en
Priority to AU2023361985A priority patent/AU2023361985B2/en
Priority to JP2023560923A priority patent/JP2025516407A/ja
Priority to EP23887181.8A priority patent/EP4702974A1/en
Priority to TW112140586A priority patent/TW202442220A/zh
Priority to IL312531A priority patent/IL312531A/en
Publication of CN118892446A publication Critical patent/CN118892446A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202310476403.2A 2023-04-27 2023-04-27 一种含vvn001的眼科组合物 Pending CN118892446A (zh)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CN202310476403.2A CN118892446A (zh) 2023-04-27 2023-04-27 一种含vvn001的眼科组合物
PCT/CN2023/096273 WO2024221527A1 (zh) 2023-04-27 2023-05-25 一种含vvn001的眼科组合物
KR1020247022421A KR20240159657A (ko) 2023-04-27 2023-05-25 Vvn001을 함유하는 안과 조성물
CA3238321A CA3238321A1 (en) 2023-04-27 2023-05-25 A vvn001-containing ophthalmic composition
AU2023361985A AU2023361985B2 (en) 2023-04-27 2023-05-25 A vvn001-containing ophthalmic composition
JP2023560923A JP2025516407A (ja) 2023-04-27 2023-05-25 Vvn001含有眼科組成物
EP23887181.8A EP4702974A1 (en) 2023-04-27 2023-05-25 Ophthalmic composition containing vvn001
TW112140586A TW202442220A (zh) 2023-04-27 2023-10-24 一種含vvn001的眼科組合物
IL312531A IL312531A (en) 2023-04-27 2024-05-01 Preparations for intraocular administration containing VVN001

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310476403.2A CN118892446A (zh) 2023-04-27 2023-04-27 一种含vvn001的眼科组合物

Publications (1)

Publication Number Publication Date
CN118892446A true CN118892446A (zh) 2024-11-05

Family

ID=93255459

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310476403.2A Pending CN118892446A (zh) 2023-04-27 2023-04-27 一种含vvn001的眼科组合物

Country Status (9)

Country Link
EP (1) EP4702974A1 (https=)
JP (1) JP2025516407A (https=)
KR (1) KR20240159657A (https=)
CN (1) CN118892446A (https=)
AU (1) AU2023361985B2 (https=)
CA (1) CA3238321A1 (https=)
IL (1) IL312531A (https=)
TW (1) TW202442220A (https=)
WO (1) WO2024221527A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0589020A4 (en) * 1992-03-18 1994-07-06 Coopervision Pharma Verapamil hcl formulation and other ophthalmic solutions with buffer system for ocular administration
US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
HUE059052T2 (hu) * 2014-11-07 2022-10-28 Santen Pharmaceutical Co Ltd Vizes szemészeti készítmény
WO2019001171A1 (zh) * 2017-06-27 2019-01-03 维眸生物科技上海有限公司 一种含磷化合物及其制备和应用
CN109134533B (zh) * 2017-06-27 2020-08-11 维眸生物科技(上海)有限公司 一种含磷化合物及其制备和应用
CN114533652B (zh) * 2018-09-25 2024-12-13 沈阳兴齐眼药股份有限公司 药物组合物、其制备方法和用途
US20230172946A1 (en) * 2019-08-18 2023-06-08 Iview Therapeutics, Inc. In-situ Gel Forming Ophthalmic Formulations Containing Difluprednate
IT202000027155A1 (it) * 2020-11-12 2022-05-12 Sifi Spa Formulazione a base di poliesametilene biguanide per il trattamento della cheratite da acanthamoeba
PL4312986T3 (pl) * 2021-04-01 2025-02-17 Active Biotech Ab Preparat lakwinimodu do stosowania do oczu

Also Published As

Publication number Publication date
TW202442220A (zh) 2024-11-01
EP4702974A1 (en) 2026-03-04
JP2025516407A (ja) 2025-05-30
AU2023361985A1 (en) 2024-11-14
KR20240159657A (ko) 2024-11-05
CA3238321A1 (en) 2025-07-08
AU2023361985B2 (en) 2025-08-14
IL312531A (en) 2024-11-01
WO2024221527A1 (zh) 2024-10-31

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