CN1187365A - Oral liquid for removing intense heat from throat and preparing process thereof - Google Patents

Oral liquid for removing intense heat from throat and preparing process thereof Download PDF

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Publication number
CN1187365A
CN1187365A CN 97122015 CN97122015A CN1187365A CN 1187365 A CN1187365 A CN 1187365A CN 97122015 CN97122015 CN 97122015 CN 97122015 A CN97122015 A CN 97122015A CN 1187365 A CN1187365 A CN 1187365A
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minutes
hours
qingyan
weight
oral
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CN 97122015
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Chinese (zh)
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CN1057227C (en
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辛孟芬
赵金生
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辛孟芬
赵金生
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Abstract

An oral liquid for making throat comfortable is prepared from 12 Chinese-medicinal materials such as dendrobium, tangerine peel, scrophularia root, rehmannia root, honeysuckle flower, etc. through high-pressure decocting twice, filter, reduced pressure concentration, alcohol extraction and boiling, and features simple preparing process and high effect.

Description

清咽口服液及其制备方法 Oral and preparation method qingyan

本发明涉及一种清咽口服液及其制备方法。 The present invention relates to a method of preparing oral and Qingyan.

目前临床用于治疗咽喉肿痛的清热制剂较多,而大多数复配中草药制剂存在着各组分配伍不好,疗效不显著等缺点。 Current clinical formulations for more heat treatment of sore throat, and most complex herbal preparations there each component compatibility is not good, the effect is not significant shortcomings.

本发明的目的在于提供一种清咽口服液及其制备方法,以克服现有技术之不足。 Object of the present invention is to provide an oral liquid preparation method qingyan to overcome the deficiencies of the prior art.

本发明的药物组成是(单位重量份):南沙参 10-18 生地 8-15 麦冬 15-25石斛 8-15 金银花 10-20 薄荷 5-9陈皮 8-15 枳壳 8-15 桔梗 3-9玄参 8-15 黄岑 15-30 甘草 8-15本发明的制备方法是:将上述药物洗净,经高压水煎两次,第一次加入为上述药物组分3-8倍重量的水,煎煮1.5-2小时,第二次加入上述药物组分3-5倍重量的水煎0.5-1.5小时,然后将两次药液合并过滤,减压浓缩至相对密度为1.15-1.2,放冷后在药液中加入85-90%的乙醇溶液,使混合液含醇达55-60%,搅拌10分钟,静置16-24小时,将上清液滤至洁净容器内,回收乙醇使药液含醇量低于10%,加入甜矫味剂及适量苯甲酸钠,煮沸15分钟后加蒸馏水至混合液体积为30ml,灌装后经100℃、30分钟灭菌即可。 The pharmaceutical composition of the present invention is (in parts by weight): 10-18 Adenophorae Radix Rehmannia 8-15 15-25 10-20 mint honeysuckle Dendrobium 8-15 5-9 8-15 Citrus aurantium 8-15 grandiflorum 3- preparation 9 Scutellaria Scrophulariaceae 8-15 15-30 8-15 licorice of the present invention are: the aforementioned pharmaceutical washed twice by high pressure decoction, was added to the above-described first 3-8 times the weight of the drug component water, boiling for 1.5-2 hours, a second addition of 3-5 times the weight of the drug component decoction 0.5-1.5 hours, and then filtered twice liquid were combined and concentrated under reduced pressure to a relative density of 1.15-1.2, after adding the chemical solution in 85-90% ethanol solution, the mixed solution containing 55-60% of an alcohol, stirred for 10 minutes, allowed to stand for 16-24 hours, the supernatant was filtered into a clean container, recovering ethanol after the drug solution is less than 10% alcohol content, add sweet flavoring agent amount of sodium benzoate, boiled for 15 minutes the mixture was added distilled water to a volume of 30ml, after filling through 100 ℃, 30 minutes can be sterilized.

高压水煎时压力为1.5个大气压。 High pressure decoction pressure of 1.5 atm.

以下结合实施例对本发明作进一步描述:实施例1:南沙参 10g 金银花 10g 桔梗 3g生地 8g 薄荷 5g 玄参 8g麦冬 15g 陈皮 8g 黄岑 15g石斛 8g 枳壳 8g 甘草 8g The following examples of the present invention is further described: Example 1: Adenophorae honeysuckle 10g 10g 8g grandiflorum habitat mint 5g 3g 8g Scrophularia Radix Scutellaria 15g 15g 8g Citrus aurantium Dendrobium 8g 8g 8g licorice

制备方法是:称取上述药材洗净,经1.5个大气压水煎两次,第一次加6倍于上述药物重量的水煎1.5小时,第二次加4倍于上述药物重量的水煎1小时,然后将两次药液合并过滤,减压浓缩至相对密度为1.2,放冷,加入90%乙醇溶液,使溶液含醇量达60%,搅拌10分钟,静置20小时后将上清液滤至洁净容器内,回收乙醇,使药液含醇量达8%,加入甜矫味剂及苯甲酸钠适量,煮沸15分钟,加蒸馏水至30ml,灌装后经100℃、30分钟灭菌即可。 Preparation method: Weigh the above wash herbs, dried decoction 1.5 atmospheres twice, once to 6 times the weight of the medicine decoction 1.5 hours, four times of the second to the weight of the drug decoction 1 h, then the combined liquid was filtered twice, and concentrated under reduced pressure after the relative density of 1.2, allowed to cool, added with 90% ethanol, and the solution of 60% alcohol content, stirred for 10 minutes, the supernatant was allowed to stand for 20 hours the solution was filtered into a clean container, recovering ethanol to liquid alcohol content of 8%, was added sweet flavoring agents, sodium benzoate, boil for 15 minutes, add distilled water to 30ml, after filling through 100 ℃, 30 minutes sterilization It can be.

实施例2:南沙参 18g 生地 15g 麦冬 25g石斛 15g 金银花 20g 薄荷 9g陈皮 15g 枳壳 15g 桔梗 9g玄参 15g 黄岑 30g 甘草 15g制备方法同实施例1。 Example 2: Radix Adenophorae habitat 15g 18g 25g 15g Dendrobium honeysuckle 20g 15g mint Citrus aurantium 15g 9g 9g figwort Campanulaceae licorice 15g 30g 15g Scutellaria prepared in Example 1.

本发明中各药物组分作用是:南沙参、地生、麦冬、玄参、石斛等中药有养阴、清热、降火,并有清肺益胃作用,薄荷、枳壳又具疏风、破气、散热、消积之功。 The present invention is the role of each drug component: Adenophorae, were born, Ophiopogon, Scrophulariaceae, Dendrobium medicine has yin, heat, pathogenic fire, clearing the lungs and stomach action, mint, Citrus aurantium and having Shufeng , broken gas, heat, power consumption of the product. 金银花、黄岑具清热解毒、泻火、澡湿之功,桔醒具止咳、化痰之作用,甘草解毒、调和诸药。 Honeysuckle, Scutellaria with detoxification, purging fire, wet bath of power, with orange wake cough, phlegm, the licorice detoxification, reconcile the various drugs.

本发明所取得的技术进步及实质性特点在于:本发明所选用各药物组分适当,配伍合理,制备方法简便,具有清热解毒、消肿止痛、清热利肺、滋阴利咽之功能。 Technical progress and essential characteristics of the present invention is achieved in that: each of the selected drug component of the present invention appropriate and reasonable compatibility, easy preparation, having detoxification, swelling and pain, heat LIFEI, Yin pharynx function.

Claims (3)

1.清咽口服液,其特征在于其药物组成是(单位重量份):南沙参 10-18 生地 8-15 麦冬 15-25石斛 8-15 金银花 10-20 薄荷 5-9陈皮 8-15 枳壳 8-15 桔梗 3-9玄参 8-15 黄岑 15-30 甘草 8-15 1. Qingyan oral, characterized in that it is a pharmaceutical composition (in parts by weight): 10-18 Adenophorae Radix Rehmannia 8-15 15-25 10-20 mint honeysuckle Dendrobium 8-15 5-9 8-15 Citrus Citrus aurantium figwort 8-15 3-9 8-15 bellflower licorice Scutellaria 15-30 8-15
2.根据权利要求1所述的清咽口服液的制备方法,其特征在于将上述药物洗净,经高压水煎两次,第一次加入为上述药物组分3-8倍重量的水,煎煮1.5-2小时,第二次加入上述药物组分3-5倍重量的水煎0.5-15小时,然后将两次药液合并过滤,减压浓缩至相对密度为1.15-1.2,放冷后在药液中加入85-90%的乙醇溶液,使混合液含醇达55-60%,搅拌10分钟,静置16-24小时,将上清液滤至洁净容器内,回收乙醇使药液含醇量低于10%,加入甜矫味剂及适量苯甲酸钠,煮沸15分钟后加蒸馏水至混合液体积为30ml,灌装后经100℃、30分钟灭菌即可。 The production method according to claim 1 Qingyan oral liquid, wherein the aforementioned drug wash, decoction twice by high pressure, the first addition is 3-8 times the weight of the drug component of water, boiling for 1.5-2 hours, a second addition of 3-5 times the weight of the drug component 0.5-15 hours decoction, combined liquid was then filtered twice, and concentrated under reduced pressure to a relative density of 1.15-1.2, allowed to cool after addition of the chemical solution in 85-90% ethanol solution, the mixed solution containing 55-60% of an alcohol, stirred for 10 minutes, allowed to stand for 16-24 hours, the supernatant was filtered into a clean container, the recovery of ethanol so that the drug after the amount of alcohol solution containing less than 10%, the sweet flavoring agent amount added to sodium benzoate, boiled for 15 minutes the mixture was added distilled water to a volume of 30ml, after filling through 100 ℃, 30 minutes can be sterilized.
3.根据权利要求2所述的清咽口服液的制备方法,其特征在于高压水煎时压力为1.5个大气压。 3. Preparation method of claim 2 Qingyan oral claim, characterized in that the high-pressure water to cook the pressure is 1.5 atm.
CN97122015A 1997-12-15 1997-12-15 Throat-clearing oral liquor and preparation method CN1057227C (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102217796A (en) * 2010-04-19 2011-10-19 华芳烟用香料有限公司 Preparation of compound polysaccharide humectant and application of compound polysaccharide humectant to cigarettes
CN101658632B (en) * 2009-08-27 2012-06-27 广州白云山和记黄埔中药有限公司 Chinese herbal preparation for treating chronic pharyngitis and preparation method thereof
CN103494941A (en) * 2013-10-28 2014-01-08 卞佳林 Traditional Chinese medicine composite for treating pharyngitis and preparation method thereof and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1135899A (en) * 1995-05-12 1996-11-20 郝杰 Formulation of medicine for sore-throat and its preparation
CN1142377A (en) * 1995-08-04 1997-02-12 胶州市中医医院 Chinese medicine prescription for chronic pharyngitis and preparation thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658632B (en) * 2009-08-27 2012-06-27 广州白云山和记黄埔中药有限公司 Chinese herbal preparation for treating chronic pharyngitis and preparation method thereof
CN102217796A (en) * 2010-04-19 2011-10-19 华芳烟用香料有限公司 Preparation of compound polysaccharide humectant and application of compound polysaccharide humectant to cigarettes
CN103494941A (en) * 2013-10-28 2014-01-08 卞佳林 Traditional Chinese medicine composite for treating pharyngitis and preparation method thereof and application thereof
CN103494941B (en) * 2013-10-28 2015-06-03 卞佳林 Traditional Chinese medicine composite for treating pharyngitis and preparation method thereof and application thereof

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