CN118304366A - Lipid-lowering traditional Chinese medicine composition and preparation method and application thereof - Google Patents
Lipid-lowering traditional Chinese medicine composition and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for reducing blood lipid, and a preparation method and application thereof. The composition comprises the following raw materials: yeast, fried hawthorn, fried malt, pseudo-ginseng, astragalus, lotus leaf, cassia seed, hovenia dulcis thunb, rhizoma atractylodis, dried orange peel and dried balsam pear. The medicinal composition is prepared from the medicinal materials of Jianqu, fried hawthorn and fried malt, and has the effects of resolving turbidity, reducing lipid, promoting digestion and strengthening spleen; the dried balsam pear, the semen hoveniae, the semen cassiae and the lotus leaves have the effects of clearing heat and detoxicating and resolving dampness and reducing blood, and are taken as ministerial drugs; the Jian qu, the hawthorn and the lotus leaf are target drugs for eliminating paste and reducing turbidity and are commonly combined for treating dyslipidemia and obesity; 37. the rhizoma atractylodis, the dried orange peel and the astragalus have the effects of activating blood circulation, removing blood stasis, promoting qi circulation, strengthening spleen, eliminating dampness and resolving phlegm together and are used as adjuvant drugs; the above medicines are combined to form the preparation for resolving turbidity, reducing blood lipid, promoting qi circulation, resolving food stagnation, clearing heat, removing dampness, promoting blood circulation and removing blood stasis. Can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness, and blood stasis, manifested by dizziness, chest distress, pain, anorexia, dyspepsia, obesity, asthenia, and palpitation.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for reducing blood lipid, and a preparation method and application thereof.
Background
Hyperlipidemia is a common and frequently occurring disease, which seriously affects the quality of life of patients. Hyperlipidemia is not seen in China, the incidence rate is far lower than that of Europe and America, but with the development of socioeconomic development, the gradual improvement of the living standard of people and the change of dietary structure and living habit, the incidence rate of the diseases is in an ascending trend in China.
Hyperlipidemia is mainly diagnosed as dizziness, chest stuffiness and pain in Chinese medicine and national medicine theory. Improper diet, phlegm-fluid retention, and blood stasis are important factors for vertigo, chest stuffiness and pain. The general theory of pulse treatment and dizziness is "improper diet, excessive food, strong stomach energy and energy, weak spleen failing to transform, staying in the middle-jiao, and the people with fire develop phlegm and the people without fire coagulate fluid. Zhongzhou accumulation, clear-headed suffocation, but nausea and dizziness are enough. Therefore, improper diet can damage spleen and stomach, resulting in spleen failing to transport, food essence failing to transform, and body fluid failing to distribute, so as to gather dampness and produce phlegm, and phlegm-dampness obstructing middle energizer, so that clear yang does not rise, turbid yin does not fall, and clear orifices are blocked to cause dizziness. The "the disease is due to pulse" has clouds: the symptoms of chest obstruction caused by improper diet, hunger and saturation injury, phlegm coagulation and blood stagnation, turbid middle energizer and food retention and chest distress are all considered. It can be seen that long-term consumption of the ointment Liang Houwei or greasy substances, or overfeeding of the cold food, can cause damage to the spleen and stomach in the middle energizer, dysfunction of transportation and transformation, disturbance of body fluid metabolism, accumulation of dampness into phlegm, excessive phlegm, obstruction of blood circulation, and obstruction of heart vessels to chest obstruction. Zhang Zhongjing was carried in jin Kui Lv Jiu: the heart has branch drink, and the people feel bitter and dizzy, and the alisma decoction is the main part. Primordial Zhu Danxi advocates the theory of phlegm-fire causing dizzy, the theory of Danxi heart method, dizziness: dizziness, phlegm with qi deficiency and fire, phlegm-resolving herbs with qi-tonifying and fire-reducing herbs. While "the" Zhengzhi Zhi Sheng "carries" the knowledge that all diseases occur in qi, but not blood is the fetus of the disease. "Lin Zhi Yu Yi Su Tang" by Ye Tianshi also means "big meridian qi, collateral leading to blood, blood stasis due to long-term illness", "early qi stagnation in the meridian, and blood injury into collaterals due to long-term illness". For the theory of blood syndromes: phlegm can also be transformed into blood stasis. Modern researches have shown that chronic patients have slow blood flow, high blood viscosity and slow metabolism. These are all theories of blood turbidity, phlegm dampness and blood stasis caused by long-term disease.
Therefore, the traditional Chinese medicine composition which accords with the theory of traditional Chinese medicine and national medicine and can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness and blood stasis, with symptoms of dizziness, chest distress and pain, anorexia or indigestion after eating, obesity, hypodynamia, palpitation and the like, can also be used for the adjuvant treatment of other cardiovascular and cerebrovascular diseases caused by hyperlipidemia or diabetes and hypertension complicated with hyperlipidemia, and is the current key research direction.
Disclosure of Invention
In order to solve the technical problems in the prior art, the invention provides a traditional Chinese medicine composition for reducing blood fat and a preparation method and application thereof. The method is realized by the following technical scheme:
A Chinese medicinal composition for reducing blood lipid comprises the following raw materials: yeast, fried hawthorn, fried malt, pseudo-ginseng, astragalus, lotus leaf, cassia seed, hovenia dulcis thunb, rhizoma atractylodis, dried orange peel and dried balsam pear.
Further, the weight portions of the raw materials are as follows: 5-15 parts of Jianqu, 5-15 parts of fried hawthorn, 5-15 parts of fried malt, 2-6 parts of pseudo-ginseng, 5-15 parts of astragalus, 5-15 parts of lotus leaf, 5-15 parts of semen cassiae, 5-15 parts of semen hoveniae, 3-9 parts of rhizoma atractylodis, 2-6 parts of dried orange peel and 5-15 parts of dried balsam pear. Preferably, the weight portions of the raw materials are as follows: 5 parts of Jianqu, 5 parts of fried hawthorn, 6 parts of fried malt, 2 parts of pseudo-ginseng, 5 parts of astragalus, 5 parts of lotus leaf, 5 parts of semen cassiae, 5 parts of semen hoveniae, 3 parts of rhizoma atractylodis, 2 parts of dried orange peel and 5 parts of dried balsam pear.
The traditional Chinese medicine composition can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness and blood stasis, and symptoms such as dizziness, chest distress and pain, inappetence, dyspepsia, obesity, hypodynamia, palpitation and the like. Can also be used for the adjuvant treatment of other cardiovascular and cerebrovascular diseases or diabetes and hypertension complicated with hyperlipidemia caused by hyperlipidemia. The hyperlipidemia and hypertension, coronary heart disease and diabetes combined with hyperlipidemia in modern medicine are mainly manifested as dizziness, chest stuffiness and pain, which can be dialectically used. The traditional Chinese medicine composition disclosed by the application can be applied to the aspects of lipid-lowering medicines, hyperlipidemia medicines, other cardiovascular and cerebrovascular diseases caused by hyperlipidemia or medicines for diabetes mellitus, hypertension complicated with hyperlipidemia, dizziness, chest stuffiness and pains and the like.
The traditional Chinese medicine composition can also be prepared into any clinically acceptable dosage form, including but not limited to granules, decoction and the like.
The preparation method of the decoction comprises the steps of taking raw materials such as Jian qu, fried hawthorn, fried malt, pseudo-ginseng, astragalus, lotus leaf, semen cassiae, semen hoveniae, rhizoma atractylodis, dried orange peel, dried balsam pear and the like according to a proportion, and decocting the raw materials with water.
The traditional Chinese medicine composition provided by the application comprises the following components:
In the recipe, massa Medicata Fermentata, parched fructus crataegi and parched fructus Hordei Germinatus are all used as principal drugs. Wherein, the Jian Qu Xingwen is sweet and spicy in taste, enters spleen channels and stomach channels, has the effects of reducing blood fat, promoting digestion, regulating qi and resolving dampness, and is mainly used for treating the impairment of chest and abdomen, abdominal distention, vomiting and diarrhea. The Jian qu is derived from medicated leaven, and is a solid preparation prepared by fermenting Chinese herbal medicines, which is originally carried in the theory of medicine. "digestion-promoting stagnation, antidiarrheal and spleen and stomach strengthening" in the new ginseng decoction pieces ". Modern researches show that Jianqu can reduce cholesterol, triglyceride and low-density lipoprotein cholesterol, thereby achieving the effect of reducing blood fat. The fried hawthorn is slightly warm in nature and sour and sweet in taste, enters spleen channels, stomach channels and liver channels, and has the effects of resolving turbidity and reducing lipid, promoting digestion and invigorating stomach, promoting qi circulation and removing blood stasis, and treating meat stagnation, abdominal mass, phlegm retention, flatulence and fullness in stomach, hyperlipidemia and the like. Description of the outline: food retention, abdominal mass, phlegm-fluid retention, distention and fullness, acid regurgitation, blood stagnation, pain and distention. "Ben Cao Renewness" carried: treating spleen deficiency and damp-heat, promoting digestion and removing food retention, and facilitating urination and defecation. Modern researches show that citric acid, quinic acid, rutin, vitexin-4, -O-glucoside, vitexin-2, -O-rhamnoside and malic acid in the haw ingredient have the effects of eliminating turbid and reducing blood lipid. Malt is neutral in nature, sweet in taste, enters spleen and stomach meridian, promotes qi to promote digestion, invigorates spleen and stimulates appetite, and is used for treating indigestion, abdominal distention and pain, spleen deficiency and anorexia, and malt frying is preferential to promoting qi to promote digestion. The Chinese pharmacopoeia records "roasted malt: promoting qi circulation, clearing food and promoting lactation, and can be used for treating dyspepsia and female weaning. "drug theory: digestion for food retention, cold-dispelling, and relieving abdominal distention. The Jian qu, the fried hawthorn and the fried malt have the effects of resolving turbidity, reducing lipid, promoting digestion and strengthening spleen and are all monarch drugs.
Bitter gourd is dry in formula, cold in nature, bitter in taste, and enters heart, lung, spleen and stomach meridians, clears summer heat, clears liver and improves vision, clears heat and detoxifies, and is used for treating febrile disease, polydipsia, damp-heat diarrhea, liver heat, conjunctival congestion, pain, carbuncle, erysipelas and the like. Yunnan Ben Cao (materia Medica): "treating toxic qi due to Dan Huo, malignant boil with toxic toxicity, or sesame furuncle pain after body pass. Purging excessive fire in six channels, clearing summer-heat, tonifying qi and quenching thirst. "Shengsheng plaited: eliminating pathogenic heat, jie Laofa, clearing away heart-fire and improving eyesight. "materia medica true: "remove dysphoria". The hovenia dulcis thunb has the effects of quenching thirst, relieving restlessness, stopping vomiting and relieving constipation, and is mainly used for treating polydipsia, dysphoria with smothery sensation, vomiting, difficult urination and the like. The "materia Medica pickup Yi": "slake thirst and relieve restlessness, moisten five viscera, relieve constipation and remove upward heat from the diaphragm", it is used as honey. Semen Cassiae, bitter, sweet and salty in taste, and slightly cold in nature, enters liver, kidney and large intestine channels; has effects of clearing liver-fire, improving eyesight, loosening bowel to relieve constipation, and can be used for treating conjunctival congestion, pain, headache, dizziness, and constipation. Relaxing bowel, reducing blood lipid, improving eyesight, and treating constipation, hyperlipidemia and hypertension; clearing liver-fire, improving vision, promoting diuresis, relaxing bowels, reducing blood pressure and blood lipid. The Chinese herbal medicine has wide application and is carried as follows: "clear liver and kidney, improve vision, induce diuresis and relieve constipation". Is mainly used for treating conjunctival congestion, swelling and pain, photophobia, lacrimation, green blindness, sparrow eyes, headache, dizziness, dim vision, ascites due to cirrhosis, difficult urination and habitual constipation. It is indicated for swelling and tinea. Lotus leaf, spleen and stomach meridian entered, bitter in nature, entering foot taiyin and yangming meridian, has the functions of clearing away summer-heat, raising hair and clearing yang, cooling blood and stopping bleeding, and is used for summer-heat polydipsia, summer-heat and damp diarrhea, spleen deficiency diarrhea and the like. Yunnan Ben Cao (materia Medica): "the upper clear the heat of the head and eyes, stop dizziness, clear phlegm, release qi, arrest vomiting, and headache. "Ben Cao Rew": "Cooling and relieving summer-heat, quenching thirst and promoting the production of body fluid, treating diarrhea and dysentery, and relieving fever. "" medical compilation: lotus leaf, lotus root and lotus plumule, with liver being the most important part, calm heat and remove dampness to promote qi circulation and enter liver. Bitter and astringent taste, it is indicated for heart and liver diarrhea to clear gold and consolidate water, so it can remove blood stasis, preserve essence, dispel delusional heat and calm qi and blood. The bitter gourd, the hovenia dulcis thunb, the cassia seed and the lotus leaf have the effects of clearing heat and detoxicating and resolving dampness and reducing blood, and are used as ministerial drugs. Jian qu, hawthorn fruit and lotus leaf are target drugs for eliminating paste and reducing turbidity, and are often combined for treating dyslipidemia and obesity.
Notoginseng radix has sweet and slightly bitter taste, warm nature, and good effect in dispersing blood stasis, stopping bleeding, relieving swelling and pain, and nourishing liver and stomach meridian. Rhizoma atractylodis has pungent and bitter taste, warm nature, and enters spleen channel, stomach channel and liver channel, has the effects of strengthening spleen and eliminating dampness, and relieving Yu Bi filth, and is used for treating excessive dampness and spleen, listlessness and lying, epigastric fullness and distention, inappetence, vomiting, diarrhea, dysentery, malaria, phlegm-fluid, edema, common cold due to qi and time, wind-cold-dampness arthralgia, flaccidity of feet and the like. Pearl sac: it can strengthen stomach and calm spleen, and can not remove all wet swelling. Compendium, compendium: for retention of phlegm and retained fluid, or retention of blood stasis in the cuvettes, spleen-dampness flowing downward, turbid urine draining downward, diarrhea with intestinal wind. Original asking of materia medica: to stop diarrhea , to stop diarrhea due to summer heat, and to stop spleen dampness from descending blood. The lotus leaves have the effects of promoting diuresis, strengthening spleen and raising yang; the rhizoma atractylodis is pungent, warm, dry and violent in nature, and has the effects of dispelling wind and removing dampness, strengthening spleen and stopping diarrhea. The two medicines are combined together, so that the medicine has the effects of resolving dampness and eliminating turbid, and has the effect of reducing blood fat in modern pharmacology. Pericarpium Citri Tangerinae, bitter and pungent in flavor, warm in nature, and good in lung and spleen meridian, has the main effects of regulating qi-flowing, invigorating spleen, eliminating dampness and resolving phlegm, and can be used for treating abdominal distention, anorexia, vomiting and diarrhea. It is combined with shan Zha and Shen qu for food retention and qi stagnation and abdominal distention and pain. Chen Pi was first recorded in Shen nong Ben Cao Jing (Shen nong's herbal), and is listed as the top-grade product. Astragalus root, radix astragali, sweet in taste, warm in nature, and capable of invigorating qi, consolidating superficial resistance, promoting urination, removing toxic substances, expelling pus, promoting wound healing, and promoting granulation, and can be used for treating qi deficiency, debilitation, loose stool, sinking of middle-warmer, internal heat, diabetes, chronic nephritis, albuminuria, and diabetes. Shennong Ben Cao Jing (Shennong's herbal): bitter and flat. Mainly treats various fever, jaundice, diarrhea and dysentery of intestines, water-expelling, blood-blocking, malignant sore, cellulitis and ulcer. The pathogenic qi is deficient, astragalus root benefits qi to invigorate spleen, and qi circulation is to remove phlegm. 37. Rhizoma Atractylodis, pericarpium Citri Tangerinae and radix astragali together have the effects of promoting blood circulation for removing blood stasis, activating qi-flowing, invigorating spleen, eliminating dampness and resolving phlegm, and are used as adjuvant drugs.
The above medicines are combined to form the preparation for resolving turbidity, reducing blood lipid, promoting qi circulation, resolving food stagnation, clearing heat, removing dampness, promoting blood circulation and removing blood stasis. Can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness, and blood stasis, manifested by dizziness, chest distress, pain, anorexia, dyspepsia, obesity, asthenia, and palpitation. Can also be used for the adjuvant treatment of other cardiovascular and cerebrovascular diseases or diabetes and hypertension complicated with hyperlipidemia caused by hyperlipidemia. The hyperlipidemia and hypertension, coronary heart disease and diabetes combined with hyperlipidemia in modern medicine are mainly manifested as dizziness, chest stuffiness and pain, which can be dialectically used.
The lipid-flattening protocol of the application is derived from a long-term empirical summary. Modern medicine considers that hyperlipidemia is caused by excessive fat intake, abnormal lipoprotein synthesis and metabolism, and the like, and blood is milky white when severe, so that atherosclerosis can be gradually caused, and common symptoms of cardiovascular and cerebrovascular diseases such as dizziness, chest distress and pain can appear. Hyperlipidemia belongs to the categories of dizziness, chest distress, heart pain and the like in traditional Chinese medicine.
The present inventors considered that the cause of hyperlipidemia is mainly as follows: firstly, people eat the food in a poor diet, are fat, sweet, thick and greasy, drink wine like syrup, and eat for a long time to have insufficient activity; secondly, the body is weak or the spleen is deficient, the viscera is weak, and the movement is weak; thirdly, emotional disorder, anxiety and thinking about qi stagnation, incoordination between liver and spleen; and fourthly, adverse drug reactions are caused. The pathological changes of viscera are mainly related to spleen and stomach, liver and kidney. With the improvement of the life and the material level of people, the diet structure is obviously changed before, and the eating of greasy and sweet matters is obviously increased. Therefore, the underlying cause or etiology for hyperlipidemia is largely due to the sweet, thick and greasy feeling of addiction. Just like "Su-Bi Lun" cloud: the essence and qi of the food can also be regulated in the five zang organs and spread to the six fu organs, which can also enter the pulse. So the circulation goes up and down to the five zang organs and the collaterals are also the six fu organs. The Wei Zhe cereals are also a hammer. Its qi is smooth and beneficial and can not enter the pulse. As can be seen from the above, blood is produced by pure qi, and its key viscera is spleen and stomach, which is related to nutrient qi and body fluids. If the ingestion is bad, the spleen and stomach functions are impaired, spleen and soil are stagnated, and heat is transformed after a long time. In which the formation and development process is very similar to the metabolic syndrome in modern medicine. Therefore, qi is not clear, clear and turbid, and body fluids are secreted into the pulse to be turbid. The spleen failing to transport and transform can cause clear yang, turbid yin failing to descend, and clear and turbid urine being difficult to divide, so that damp turbidity is trapped in the interior, phlegm turbidity is generated internally, blood stasis is blocked, and the blood is accumulated in the pulse, and blood turbidity (blood turbidity is turbidity or confusion of blood, abnormal blood rheology, excessive metabolic products remained in blood, circulation disturbance and the like can be called blood turbidity) is also generated. "Gujin medical system da Quan, eighty of volume" cloud: "cover qi, yang; blood, yin. The blood flows inside and the qi flows outside and around. Cold and damp pulse do not cause the slow circulation of qi, and heat and fire pulse do not cause the fast circulation of qi. Qi is retained and qi is retained, so body fluids are thick and sticky, which means phlegm is retained and long-term accumulated, and blood is turbid. Therefore, it can be seen that the turbid blood is caused by pathogenic factors in blood vessels, and only the body fluids are thick and sticky. The modern famous doctor Tong Xiaolin points out the characteristic of 'turbidity': firstly, a certain substance in blood or tissues is too much, but is still in a flowing state; secondly, the disease state does not appear yet, and the disease state belongs to the early stage of the disease; thirdly, the disease can be generated by continuously or intermittently generating phlegm and removing blood stasis if turbid pathogen is continuously increased for a long time. The image is to say that the water after rain is 'turbid', and the water is deposited to a river bed to be 'phlegm', and the blocked river is 'stagnant', so that the turbid is an intermediate excessive state or excessive product. The present inventors considered that the concentration of cholesterol or triglyceride, low density lipoprotein cholesterol in the blood of a patient suffering from hyperlipidemia is too high, which is the same as the above-mentioned discussion of the ancient and modern doctors. If clear and turbid are not separated, hyperlipidemia, even abnormal blood sugar and the like are caused for a long time; metabolic hypertension may occur in severe cases due to stagnation of earth and wood, long-term heat transfer, heat and liver and gallbladder.
In summary, for hyperlipidemia, overfeeding of fei gan is the main root cause, while endogenous turbid pathogenic factors and spleen failing to strengthen and transport are the main pathogenesis, the treatment is focused on middle energizer, and simultaneously damp, accumulated heat and phlegm stasis caused by turbid pathogenic factors are taken into consideration. Therefore, it is indicated for the treatment of turbid pathogen with the actions of reducing blood lipid, promoting qi circulation to remove food stagnation, clearing heat and removing dampness, and activating blood circulation to dissipate blood stasis. The lipid-flattening protocol formula is used for treating hyperlipidemia caused by turbid blood, phlegm dampness and blood stasis, and has symptoms of dizziness, chest distress and pain, anorexia or indigestion after eating, obesity, hypodynamia, palpitation and the like, and can also be used for the adjuvant treatment of other cardiovascular and cerebrovascular diseases caused by hyperlipidemia or diabetes and hypertension complicated with hyperlipidemia.
The lipid-lowering protocol prescription consists of Massa Medicata Fermentata, parched fructus crataegi, parched fructus Hordei Germinatus, notoginseng radix, radix astragali, folium Nelumbinis, semen Cassiae, semen Hoveniae, rhizoma Atractylodis, pericarpium Citri Tangerinae, and dried fructus Momordicae Charantiae, and has effects of removing turbid pathogen, lowering blood lipid, promoting qi circulation, resolving food stagnation, clearing heat, removing dampness, promoting blood circulation, and removing blood stasis. Can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness, and blood stasis, manifested by dizziness, chest distress and pain, anorexia, dyspepsia, obesity, debilitation, palpitation, etc., and also can be used for adjuvant treatment of other cardiovascular and cerebrovascular diseases caused by hyperlipidemia or diabetes complicated with hyperlipidemia. Modern pharmacological researches have shown that the Chinese medicine in the recipe has at least one of the functions of reducing blood fat, reducing blood sugar and reducing blood pressure. Because of the large difference between the modern clinical dosage of the medicine and the dosage in ancient medical books, the dosage of the medicine is not only related to the clinical curative effect of the traditional Chinese medicine formula, but also closely related to the medication safety of the traditional Chinese medicine, and the clinical trial is carried out by establishing a fat-free protocol prescription by hospitals on the basis of ensuring the effectiveness and the safety of the medicine for the reduction of the waste and the adverse reaction of the medicine, the intensive study and the comparison of the size, the soaking, the water adding amount, the heating time, the decocting times and the decocting amount of the traditional Chinese medicine decoction pieces are carried out by repeated clinical practice, and finally the dosage is reduced to reasonable dosage. The prescription is clinically tried by taking the prescription as an agreement prescription from 2018, so far, more than 5 years of clinical practice exist, better curative effect is obtained, and adverse reaction report is not seen.
The prescription is prepared from eleven medicinal materials including medicinal starter, fried hawthorn, fried malt, pseudo-ginseng, astragalus root, lotus leaf, cassia seed, hovenia dulcis thunb, rhizoma atractylodis, dried orange peel and dried balsam pear. In the formula, the medicinal materials of the Jian qu, the fried hawthorn and the fried malt are taken as monarch, and the dried balsam pear, the semen hoveniae, the semen cassiae, the lotus leaf, the pseudo-ginseng, the rhizoma atractylodis, the dried orange peel and the astragalus root are taken as ministerial.
In the recipe, massa Medicata Fermentata, parched fructus crataegi and parched fructus Hordei Germinatus are all used as principal drugs. Wherein, the medicine is built Qu Xingwen, has sweet and pungent taste, enters spleen channels and stomach channels, has the effects of reducing blood fat, promoting digestion, regulating qi, resolving dampness and relieving exterior syndrome, and is mainly used for treating the symptoms of chest stuffiness, abdominal distention, vomiting and diarrhea, common cold headache, children hunger and hunger impairment. The Jian qu is derived from medicated leaven, and is a solid preparation prepared by fermenting Chinese herbal medicines, which is originally carried in the theory of medicine. The Chua's medicine plaster carries: treating wind-cold summer-heat and dampness, dizziness and fever, diaphoresis; can remove food retention and open chest, regulate diaphragm and stomach, strengthen the body, and achieve qi which is indefinite in four times; it can check diarrhea and resolve swelling, and treat improper diet. "decoction pieces New Ginseng radix" means "digestion-promoting stagnation, antidiarrheal, and spleen and stomach strengthening. "drug examination" describes: searching wind, relieving exterior syndrome, regulating stomach, promoting phlegm, relieving cough, malaria, dysentery, vomiting and diarrhea; can relieve Wen Yilan cataract, dispel rash and remove spots. Modern researches show that Jianqu can reduce cholesterol, triglyceride and low-density lipoprotein cholesterol, thereby achieving the effect of reducing blood fat.
The fried hawthorn fruit has slight warm nature and sweet and sour taste, enters spleen channels, stomach channels and liver channels, eliminates turbid pathogen and reduces lipid, promotes digestion and invigorating stomach, moves qi and eliminates blood stasis, and drives away tapeworm, so as to treat food stagnation, symptoms such as phlegm retention, acid regurgitation, intestinal wind, lumbago, flatulence of stomach alkane, diarrhea and abdominal pain, blood stasis amenorrhea, heart and abdomen stinging pain, hyperlipidemia and the like. Description of the outline: food retention, abdominal mass, phlegm-fluid retention, distention and fullness, acid regurgitation, blood stagnation, pain and distention. "Chan mu" is recorded again: food retention, abdominal mass, phlegm-fluid retention, distention and fullness, acid regurgitation, blood stagnation, pain and distention. "Ben Cao Renewness" carried: treating spleen deficiency and damp-heat, promoting digestion and removing food retention, and facilitating urination and defecation. Modern researches show that citric acid, quinic acid, rutin, vitexin-4, -O-glucoside, vitexin-2, -O-rhamnoside and malic acid in the haw ingredient have the effects of eliminating turbid and reducing blood lipid.
Malt, it is neutral in nature, sweet in taste, and enters spleen and stomach meridian, promoting qi circulation to promote digestion, strengthening spleen and stimulating appetite, and removing milk and distention, and can be used for treating dyspepsia, abdominal distention and pain, spleen deficiency and anorexia, milk stasis, breast distention and pain, and female weaning. The roasted malt is preferred to promote qi circulation and promote digestion. The Chinese pharmacopoeia records that the roasted malt is used for promoting qi circulation, clearing food and promoting lactation, and is used for treating indigestion and female weaning. "digestion of food, breaking of cold, and removal of distention and fullness of the heart and abdomen. "Qianjin-food therapy. "
Jian qu, fried haw and fried malt are all monarch drugs for resolving turbidity, reducing blood fat, promoting digestion and strengthening spleen.
Bitter gourd is dry, cold in nature and bitter in taste, and enters heart, lung, spleen and stomach meridians, clears summer heat, clears liver and improves vision, clears heat and detoxifies, and is used for treating febrile disease, polydipsia, heatstroke, damp-heat diarrhea, dysentery, liver heat, conjunctival congestion and pain, carbuncle, erysipelas and malignant sore. Yunnan Ben Cao (materia Medica): "treating toxic qi due to Dan Huo, malignant boil with toxic toxicity, or sesame furuncle pain after body pass. Purging excessive fire in six channels, clearing summer-heat, tonifying qi and quenching thirst. "Shengsheng plaited: eliminating pathogenic heat, jie Laofa, clearing away heart-fire and improving eyesight. "materia medica true: "remove dysphoria". "diet Spectrum with rest": the green tea can clear heat, improve eyesight and clear heart. When done, the recipe can nourish blood and nourish liver, moisten spleen and tonify kidney. "
Semen Hoveniae, with mild nature, sweet and sour taste, has the main effects of dispelling alcohol toxicity, quenching thirst, relieving restlessness, relieving vomiting and relieving constipation, and is mainly used for treating drunk, polydipsia, dysphoria with smothery sensation, emesis, dysuria and the like. The "materia Medica pickup Yi": "slake thirst and relieve restlessness, moisten five viscera, relieve constipation and remove upward heat from the diaphragm", it is used as honey. "Diannan Ben Cao": "treating all left paralysis and right paralysis, rheumatism and numbness, can dispel alcohol toxicity; or soaking in wine, it can relax tendons and collaterals. It is administered to children for removing parasites and nourishing spleen. "Dian nan Ben Cao Chart: middle-jiao and Qi tonifying. The phlegm-fire can be resolved by the accumulation in the chest. "outline of the invention: "anti-vomiting and anti-contrary". "
Semen Cassiae, bitter, sweet and salty in taste, slightly cold in nature, enters liver, kidney and large intestine meridians; has effects of clearing liver-fire, improving eyesight, loosening bowel to relieve constipation, and can be used for treating conjunctival congestion, pain, photophobia, lacrimation, headache, dizziness, dim eyesight, and constipation. Relaxing bowel, reducing blood lipid, improving eyesight, and treating constipation, hyperlipidemia and hypertension; clearing liver-fire, improving vision, promoting diuresis, relaxing bowels, reducing blood pressure and blood lipid. Compendium of materia Medica: "liver and gall wind-heat removal, skin-whitening and green blindness". "Chinese herbal medicine", said application is relatively extensive, carry as: "clear liver and kidney, improve vision, induce diuresis and relieve constipation". Is mainly used for treating conjunctival congestion, swelling and pain, photophobia, lacrimation, green blindness, sparrow eyes, headache, dizziness, dim vision, ascites due to cirrhosis, difficult urination and habitual constipation. It is indicated for swelling and tinea. "Ben Cao Jing Shu (materia Medica of the present invention): semen Cassiae is salty in taste and is bitter, sweet and slightly cold in nature and nontoxic in Bie Ji. Salty water and sweet earth qi, bitter flavor can dispel heat, smooth stomach qi, cold energy can benefit yin and dispel heat, and foot-jueyin liver-qi-regulating herbs. Enter the gallbladder and kidney. Liver opens into eyes, and mydriasis belongs to kidneys, so it is responsible for the symptoms of blindness, skin redness, white film, conjunctival congestion, pain and tear. The book of other records also treats the blue or green lips. It is also caused by qi tonifying liver and kidney because it is good for people who take the medicine for a long time. "
Lotus leaf, it enters liver, spleen and stomach meridians, has flat nature and bitter taste, enters foot taiyin and yangming meridians, has the functions of clearing summer heat, raising hair and clearing yang, cooling blood and stopping bleeding, and is used for summer heat and polydipsia, summer-heat and damp diarrhea, spleen deficiency diarrhea, blood heat and epistaxis, hematochezia metrorrhagia and the like. Yunnan Ben Cao (materia Medica): "the upper clear the heat of the head and eyes, stop dizziness, clear phlegm, release qi, arrest vomiting, and headache. "outline of the invention: "generating primordial qi, helping spleen and stomach, astringing turbid urine, dispersing blood stasis, treating edema and carbuncle, and acne. For hematemesis and hemoptysis. Epistaxis, bleeding, drowning, stranguria with blood, metrorrhagia, postpartum malignant blood, and damage and abortion. "Ben Cao Rew": "Cooling and relieving summer-heat, quenching thirst and promoting the production of body fluid, treating diarrhea and dysentery, and relieving fever. "" medical compilation: lotus leaf, lotus root and lotus plumule, with liver being the most important part, calm heat and remove dampness to promote qi circulation and enter liver. Bitter and astringent taste, it is indicated for heart and liver diarrhea to clear gold and consolidate water, so it can remove blood stasis, preserve essence, dispel delusional heat and calm qi and blood. "
The dried balsam pear, the semen hoveniae, the semen cassiae and the lotus leaves have the effects of clearing heat and detoxicating and resolving damp and reducing blood, and are used as ministerial drugs. Jian qu, hawthorn fruit and lotus leaf are target drugs for eliminating paste and reducing turbidity, and are often combined for treating dyslipidemia and obesity.
Notoginseng radix has sweet and slightly bitter taste, and warm nature, and can be used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracocentesis pain, and traumatic swelling and pain. Compendium, compendium: hemostatic, blood-dispelling and pain-relieving. The golden sword is used for treating traumatic injury, sore and bleeding, and is chewed and smeared or not doped, and the bleeding is stopped. Also has the effects of stopping bleeding, bloody dysentery, metrorrhagia, puerperal aversion to blood, blood circulation, blood pain, bleeding, carbuncle, swelling, tiger bite, snake bite. "Yu Zhong Yao Jie (solution of Yu Zhong): "Heying and stopping bleeding, promoting blood circulation and removing blood stasis, and astringing new blood. All blood stasis is broken after delivery, menstrual period, traumatic injury and carbuncle; all kinds of new blood can be treated by vomiting and epistaxis, metrorrhagia and metrostaxis, incised wound and arrow shooting. "
Rhizoma atractylodis has pungent and bitter taste, warm nature, and enters spleen channel, stomach channel and liver channel, has the effects of strengthening spleen and eliminating dampness, and relieving Yu Bi filth, and is used for treating excessive dampness and spleen, listlessness and lying, epigastric fullness and distention, inappetence, vomiting, diarrhea, dysentery, malaria, phlegm-fluid, edema, common cold due to qi and time, wind-cold-dampness arthralgia, flaccidity of feet and the like. Ceramic carrying forward: remove bad smell. Liu Wansu: improving eyesight, and warming water. Pearl sac: it can strengthen stomach and calm spleen, and can not remove all wet swelling. The preparation method comprises the following steps: essential herbs for removing dampness and sweating, invigorating stomach and spleen, and treating flaccidity. Zhu Jong: dispelling wind and invigorating qi, and relieving depression. Compendium, compendium: for retention of phlegm and retained fluid, or retention of blood stasis in the cuvettes, spleen-dampness flowing downward, turbid urine draining downward, diarrhea with intestinal wind. Medicine solution of Aronia melanocarpa: dry earth and induce diuresis, release drink and remove phlegm, remove blood stasis, resolve depression, remove leakage, remove tinea, remove symptoms, regulate acid regurgitation and remove putrefaction, and exotic mountain Sichuan communicable subtropical diseases, return flaccidity and soft bones and muscles, clear urine and remove turbidity. Original asking of materia medica: to stop diarrhea , to stop diarrhea due to summer heat, and to stop spleen dampness from descending blood. The lotus leaves have the effects of promoting diuresis, strengthening spleen and raising yang; the rhizoma atractylodis is pungent, warm, dry and violent in nature, and has the effects of dispelling wind and removing dampness, strengthening spleen and stopping diarrhea. The two medicines are combined together, so that the medicine has the effects of resolving dampness and eliminating turbid, and has the effect of reducing blood fat in modern pharmacology.
Pericarpium Citri Tangerinae, bitter and pungent in flavor, warm in nature, and capable of entering lung and spleen channels, has the main effects of regulating qi-flowing, invigorating spleen, eliminating dampness and resolving phlegm, and can be used for treating abdominal distention, anorexia, vomiting and diarrhea, cough and excessive phlegm. It is combined with shan Zha and Shen qu for food retention and qi stagnation and abdominal distention and pain. Chen Pi was first recorded in Shen nong Ben Cao Jing (Shen nong's herbal), and is listed as the top-grade product. The new-meeting citrus peel is derived from Song dynasty and has been 700 years old. The primordial Wang Haogu in the decoction Ben Cao starts to appear as a medicinal material independently. The "Bencao Beijing" describes: guangdong Xinhui Tang Chen Pi is a good herb of Sheng, chen Jiuzhe so it is called Chen Pi. "Tang Dynasty Lu Yu" tea poem "also refers to the use of orange peel to cook tea. Ming dynasty Li Zhen (herbal compendium of materia Medica): orange peel, with a thick, yellow and thick texture, with a large number of white films, is pungent and sweet in taste and is superior to the ones collected in Guang Zhong in the present day. "Guangzhong" means the new meeting of modern times. Compendium of materia Medica: orange peel, its flavor belongs to pungent, bitter and warm, bitter and energy-releasing and dryness-eliminating, xin Nengsan, warm and mild. "
Astragalus root, radix astragali, sweet in taste and warm in nature, has the effects of tonifying qi and strengthening exterior, promoting urination and expelling toxin, expelling pus and healing sore and promoting granulation, and is used for qi deficiency and hypodynamia, loose stool due to poor appetite, sinking of middle-jiao, chronic diarrhea and rectocele, hematochezia and metrorrhagia, spontaneous perspiration due to exterior deficiency, qi deficiency and edema, carbuncles and difficult ulcer, chronic ulcer and non-astringing, blood deficiency and flaccidity, internal heat and diabetes, chronic nephritis and proteinuria and diabetes. Shennong Ben Cao Jing (Shennong's herbal): bitter and flat. Mainly treats various fever, jaundice, diarrhea and dysentery of intestines, water-expelling, blood-blocking, malignant sore, cellulitis and ulcer. "Ming Yi Bie Lu (miscellaneous records of famous physicians)": "Cold, nontoxic". Mainly treats phlegm heat, stomach heat, lower abdominal cramp, cereal eliminating, small intestine benefiting, female blood obstruction, stranguria, blood discharging and infantile abdominal pain. "Japanese Sunji Ben Cao": downward flow of qi, principal heaven and activating heat, ding Chuang discharge pus, treat carbuncles with back. "drug Property excipient: bitter taste, flat, cold in nature and non-toxic. Can be raised and lowered, and yin is also. The four methods are as follows: the people with middle warmer and lower back have the effects of purging lung fire, resolving phlegm and promoting qi circulation; the people with excessive weight and hardness purge the large intestine fire, nourish yin and remove yang; if the middle warmer is dry and drifted, the wind-dampness is removed and heat is retained in the muscle surface, while if the wind-dampness is thin and firm, the pathogenic factors are nourished and the heat is removed from the bladder. "
37. Rhizoma Atractylodis, pericarpium Citri Tangerinae and radix astragali together have the effects of promoting blood circulation for removing blood stasis, activating qi-flowing, invigorating spleen, eliminating dampness and resolving phlegm, and are used as adjuvant drugs.
The above medicines are combined to form the preparation for resolving turbidity, reducing blood lipid, promoting qi circulation, resolving food stagnation, clearing heat, removing dampness, promoting blood circulation and removing blood stasis. Can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness, and blood stasis, manifested by dizziness, chest distress, pain, anorexia, dyspepsia, obesity, asthenia, and palpitation. Can also be used for the adjuvant treatment of other cardiovascular and cerebrovascular diseases or diabetes and hypertension complicated with hyperlipidemia caused by hyperlipidemia.
Compared with the prior art, the invention has the technical effects that:
The traditional Chinese medicine composition disclosed by the application has the effects of removing turbid pathogen, reducing lipid, promoting digestion and strengthening spleen by using the medicinal materials of the Jian qu, the fried hawthorn and the fried malt together, and is used as a monarch drug; the dried balsam pear, the semen hoveniae, the semen cassiae and the lotus leaves have the effects of clearing heat and detoxicating and resolving dampness and reducing blood, and are taken as ministerial drugs; the Jian qu, the hawthorn and the lotus leaf are target drugs for eliminating paste and reducing turbidity and are commonly combined for treating dyslipidemia and obesity; 37. the rhizoma atractylodis, the dried orange peel and the astragalus have the effects of activating blood circulation, removing blood stasis, promoting qi circulation, strengthening spleen, eliminating dampness and resolving phlegm together and are used as adjuvant drugs; the above medicines are combined to form the preparation for resolving turbidity, reducing blood lipid, promoting qi circulation, resolving food stagnation, clearing heat, removing dampness, promoting blood circulation and removing blood stasis. Can be used for treating hyperlipidemia caused by turbid blood, phlegm dampness, and blood stasis, manifested by dizziness, chest distress, pain, anorexia, dyspepsia, obesity, asthenia, and palpitation. Can also be used for the adjuvant treatment of other cardiovascular and cerebrovascular diseases or diabetes and hypertension complicated with hyperlipidemia caused by hyperlipidemia. The hyperlipidemia and hypertension, coronary heart disease and diabetes combined with hyperlipidemia in modern medicine are mainly manifested as dizziness, chest stuffiness and pain, which can be dialectically used.
Detailed Description
The technical scheme of the present invention is further defined below in conjunction with the specific embodiments, but the scope of the claimed invention is not limited to the description.
Example 1
(1) Weighing 5g of Jianqu, 5g of fried hawthorn, 6g of fried malt, 2g of pseudo-ginseng, 5g of astragalus, 5g of lotus leaf, 5g of semen cassiae, 5g of semen hoveniae, 3g of rhizoma atractylodis, 2g of dried orange peel and 5g of dried balsam pear.
Example 2
(1) Weighing 15g of Jianqu, 15g of fried hawthorn, 15g of fried malt, 2g of pseudo-ginseng, 5g of astragalus, 5g of lotus leaf, 5g of semen cassiae, 5g of semen hoveniae, 3g of rhizoma atractylodis, 2g of dried orange peel and 5g of dried balsam pear.
Example 3
(1) Weighing 5g of Jianqu, 5g of fried hawthorn, 5g of fried malt, 2g of pseudo-ginseng, 5g of astragalus, 15g of lotus leaf, 15g of semen cassiae, 15g of semen hoveniae, 3g of rhizoma atractylodis, 2g of dried orange peel and 15g of dried balsam pear.
Example 4
(1) Weighing 5g of Jianqu, 5g of fried hawthorn, 5g of fried malt, 6g of pseudo-ginseng, 15g of astragalus, 5g of lotus leaf, 5g of semen cassiae, 5g of hovenia dulcis thunb, 9g of rhizoma atractylodis, 6g of dried orange peel and 5g of dried balsam pear.
The specific clinical case usage is summarized as follows: lipid-lowering protocol prescription I treat patients in our hospital as a protocol prescription, and there have been clinical practices for over 5 years. The specific clinical summary is as follows:
general data
All 101 cases are diagnosed and treated in the clinic of our hospital from 1 month in 2018 to 12 months in 2022, and the Western medicine is diagnosed with hyperlipidemia, and the traditional Chinese medicine is mainly diagnosed with dizziness, chest stuffiness and heart pain.
(II) case selection
1. Diagnostic criteria
According to the Chinese medicine science, the Chinese medicine new medicine clinical study guidelines 2002 and the clinical symptoms and signs of the diseases which accord with the dizziness, the chest stuffiness and pains (the Western medicine is diagnosed as hyperlipidemia): dizziness, blurred vision, chest distress and pain, palpitation, vexation, limb heaviness, nausea and vomiting, dry and bitter taste of the mouth, abdominal distention, improper diet, debilitation, obesity, spontaneous perspiration, insomnia and amnesia, dark tongue, yellow and greasy coating or wiry and slippery pulse.
2. Inclusion criteria
① Meets the diagnostic criteria; ② Age between 25 and 80 years old; ③ The patients take the medicines for reducing blood fat, blood pressure or blood sugar and the like, and the effect on the test is smaller after evaluation; ④ Informed consent.
3. Exclusion criteria
① Is not suitable for the patients with diagnosis in traditional Chinese medicine and Western medicine; ② Patients with serious mental illness and life failure; ③ Dizziness patients caused by medicines; ④ Patients with serious heart, brain, liver, lung, kidney and blood system diseases at the beginning of treatment; ⑤ Age-dissatisfaction and allergy to the product; ⑥ Patients with cardiopulmonary resuscitation and electric defibrillation are in recent 2 months; ⑦ Patients with severe thyroid dysfunction affecting blood lipid, blood glucose metabolism; ⑧ No other subjects ended within 1 month in the near future.
(III) therapeutic methods
1. Prescription amount:
5g of Jianqu, 5g of fried hawthorn, 6g of fried malt, 2g of pseudo-ginseng, 5g of astragalus, 5g of lotus leaf, 5g of cassia seed, 5g of hovenia dulcis thunb, 3g of rhizoma atractylodis, 2g of dried orange peel and 5g of dried balsam pear
2. The usage amount is as follows: decoct with water, take one pair a day, take warm with two times. 1 course of treatment is 15 days, and 2-3 courses of treatment are used. And counting the curative effect after the treatment course is finished.
(IV) observing the index
1. General recording items
The name of the observed person, the clinic number/the hospitalization number, and the observation start date
2. Observation index
⑴ Biological index
Sex, age, residence, diet and nutrition
⑵ Therapeutic efficacy index
A. observe the curative effect of the symptoms of the traditional Chinese medicine and the improvement of the main clinical symptoms.
B. at least one of blood lipid (cholesterol, low density lipoprotein cholesterol, triglyceride).
(3) Safety observation
Vital signs before and after administration, etc.
(4) Adverse reaction light and heavy degree judgment standard
Adverse reactions such as emesis, headache, anorexia, dyspnea, rash and pruritus should be observed during clinical test, and recorded in detail.
(V) curative effect judgment criteria: if the symptoms of traditional Chinese medicine and the blood fat are inconsistent in obvious effect, effective effect and ineffective effect, the result is that the best curative effect is achieved.
1. The traditional Chinese medicine syndrome curative effect judgment standard refers to the traditional Chinese medicine new medicine clinical research guidelines 2002:
① Clinical cure: the clinical symptoms and signs disappear or disappear basically, and the integral of the symptoms is reduced by more than or equal to 90 percent;
② The effect is shown: the clinical symptoms and signs are obviously improved, and the integral of symptoms is reduced by more than or equal to 70 percent;
③ The method is effective: the clinical symptoms and signs are improved, and the integral of the symptoms is reduced by more than or equal to 30 percent;
④ Invalidation: the clinical symptoms and signs are not obviously improved or even aggravated, and the integral of the symptoms is reduced by less than 30 percent.
2. The curative effect of blood fat:
The efficacy evaluation standard is formulated by referring to the guidelines 2002 of clinical study of New Chinese medicine.
Hyperlipidemia effect judgment:
① Clinical control: each laboratory check returned to normal range.
② The effect is shown: the blood fat is up to any one of the following conditions, the TC is reduced by more than or equal to 20 percent, the TC is reduced by more than or equal to 40 percent, the HDL-C is increased by more than or equal to 0.26moml/L, and the TC-HDL-C/HDL-C is reduced by more than or equal to 20 percent.
③ The method is effective: the blood fat is up to any one of the following conditions, the decrease of TC is more than or equal to 10% but less than 20%, the decrease of TC is more than or equal to 20% but less than 40%, the rise of HDL-C is more than or equal to 0.104moml/L but less than 0.26moml/L, and the decrease of TC-HDL-C/HDL-C is more than or equal to 10% but less than 20%.
④ Invalidation: the blood fat detection does not reach the above standard.
And (six) result:
1. total number of patients treated in 2018, 01 month and 2022, 12 months are 101, wherein 21 patients are clinically cured, 26 patients are clinically cured, 42 patients are effectively cured, and 12 patients are not effectively cured; the cure rate is 20.8%, the obvious efficiency is 25.7%, the effective rate is 41.6%, the failure rate is 11.9%, and the total effective rate is 88.1%. See in particular table 1:
Table 1 Flat fat protocol prescription clinical efficacy example (%)
2. Adverse reaction and safety: no significant adverse reactions were seen during the treatment of the patients, see table 2.
TABLE 2 adverse reaction conditions for clinical use of lipid-flattening protocol
The results indicate that the prescription has good curative effects on dizziness diseases and chest stuffiness and pains caused by hyperlipidemia, and has no obvious adverse reaction and toxic and side effects on vital signs and adverse reaction examination before and after treatment of patients, and the prescription is safe to use according to the planned dosage, usage and treatment course.
Finally, it should be noted that the above embodiments are merely representative examples of the present invention. Obviously, the technical solution of the invention is not limited to the above-described embodiments, but many variations are possible. All modifications directly derived or suggested to one skilled in the art from the present disclosure should be considered as being within the scope of the present invention.
Claims (10)
1. A traditional Chinese medicine composition for reducing blood fat is characterized by comprising the following raw materials: yeast, fried hawthorn, fried malt, pseudo-ginseng, astragalus, lotus leaf, cassia seed, hovenia dulcis thunb, rhizoma atractylodis, dried orange peel and dried balsam pear.
2. The traditional Chinese medicine composition according to claim 1, wherein the raw materials are in parts by weight: 5-15 parts of Jianqu, 5-15 parts of fried hawthorn, 5-15 parts of fried malt, 2-6 parts of pseudo-ginseng, 5-15 parts of astragalus, 5-15 parts of lotus leaf, 5-15 parts of semen cassiae, 5-15 parts of semen hoveniae, 3-9 parts of rhizoma atractylodis, 2-6 parts of dried orange peel and 5-15 parts of dried balsam pear.
3. The traditional Chinese medicine composition according to claim 1, wherein the raw materials are in parts by weight: 5 parts of Jianqu, 5 parts of fried hawthorn, 6 parts of fried malt, 2 parts of pseudo-ginseng, 5 parts of astragalus, 5 parts of lotus leaf, 5 parts of semen cassiae, 5 parts of semen hoveniae, 3 parts of rhizoma atractylodis, 2 parts of dried orange peel and 5 parts of dried balsam pear.
4. The use of the Chinese medicinal composition of claim 1 as or in the preparation of a lipid-lowering medicament.
5. The use of the Chinese medicinal composition according to claim 1 as or in the preparation of a medicament for hyperlipidemia.
6. The Chinese medicinal composition as claimed in claim 1, which is used for preparing medicines for treating other cardiovascular and cerebrovascular diseases caused by hyperlipidemia or diabetes and hypertension complicated with hyperlipidemia.
7. The use of the Chinese medicinal composition according to claim 1 as or in the preparation of medicaments for vertigo, chest stuffiness and pain.
8. A granule prepared using the Chinese medicinal composition of claim 1.
9. A decoction prepared using the traditional Chinese medicine composition of claim 1.
10. The decoction preparation method of claim 9, which is prepared by decocting materials such as Jian qu, parched fructus crataegi, parched fructus Hordei Germinatus, notoginseng radix, radix astragali, folium Nelumbinis, semen Cassiae, semen Hoveniae, rhizoma Atractylodis, pericarpium Citri Tangerinae, and dried fructus Momordicae Charantiae in water.
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