CN118184797A - 基于vsig8的嵌合蛋白 - Google Patents
基于vsig8的嵌合蛋白 Download PDFInfo
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- CN118184797A CN118184797A CN202410306323.7A CN202410306323A CN118184797A CN 118184797 A CN118184797 A CN 118184797A CN 202410306323 A CN202410306323 A CN 202410306323A CN 118184797 A CN118184797 A CN 118184797A
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- chimeric protein
- ox40l
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- C07K14/4703—Inhibitors; Suppressors
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- C07—ORGANIC CHEMISTRY
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70517—CD8
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/62—DNA sequences coding for fusion proteins
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| CN201880010430.8A CN110290798B (zh) | 2017-02-27 | 2018-02-27 | 基于vsig8的嵌合蛋白 |
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| EP3986442A4 (en) * | 2019-06-21 | 2023-10-25 | Shattuck Labs, Inc. | Chimeric protein expressing t-cells |
| KR20240037285A (ko) * | 2021-07-26 | 2024-03-21 | 카이트 파마 인코포레이티드 | Dnvsig3 및 dnvsig8 수용체 및 이의 사용 방법 |
| WO2024123812A1 (en) | 2022-12-05 | 2024-06-13 | Shattuck Labs, Inc. | Fusion proteins for the treatment of cardiometabolic diseases |
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| SG10201807625PA (en) | 2014-11-17 | 2018-10-30 | Genentech Inc | Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists |
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| US20200071378A1 (en) | 2020-03-05 |
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| US11192934B2 (en) | 2021-12-07 |
| CN110290798A (zh) | 2019-09-27 |
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