CN118159301A - 生产基因修饰的细胞的方法 - Google Patents

生产基因修饰的细胞的方法 Download PDF

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Publication number
CN118159301A
CN118159301A CN202280067317.XA CN202280067317A CN118159301A CN 118159301 A CN118159301 A CN 118159301A CN 202280067317 A CN202280067317 A CN 202280067317A CN 118159301 A CN118159301 A CN 118159301A
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cells
rna
cell
sequence
car
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English (en)
Chinese (zh)
Inventor
金晟侃
J-C·科兰特斯
J·兰伯恩
I·波雷卡
T·塞尔米
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HAPLOGEN GENOMICS GmbH
Rutgers State University of New Jersey
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HAPLOGEN GENOMICS GmbH
Rutgers State University of New Jersey
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    • A61K40/41—Vertebrate antigens
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N9/14—Hydrolases (3)
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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CN202280067317.XA 2021-08-06 2022-08-05 生产基因修饰的细胞的方法 Pending CN118159301A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163203996P 2021-08-06 2021-08-06
US63/203,996 2021-08-06
PCT/US2022/074625 WO2023015307A1 (en) 2021-08-06 2022-08-05 Method for producing genetically modified cells

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Publication Number Publication Date
CN118159301A true CN118159301A (zh) 2024-06-07

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CN202280067317.XA Pending CN118159301A (zh) 2021-08-06 2022-08-05 生产基因修饰的细胞的方法

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US (1) US20250109413A1 (https=)
EP (1) EP4380627A1 (https=)
JP (1) JP2024534720A (https=)
KR (1) KR20240043783A (https=)
CN (1) CN118159301A (https=)
AU (1) AU2022324118A1 (https=)
CA (1) CA3227964A1 (https=)
WO (1) WO2023015307A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7044373B2 (ja) 2015-07-15 2022-03-30 ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー ヌクレアーゼ非依存的な標的化遺伝子編集プラットフォームおよびその用途
WO2025070822A1 (ja) * 2023-09-29 2025-04-03 味の素株式会社 Ｈｌａ遺伝子改変細胞
WO2025117745A1 (en) * 2023-12-01 2025-06-05 Caribou Biosciences, Inc. Methods and compositions for improving precision of endonuclease-mediated genome editing
WO2025179057A1 (en) * 2024-02-21 2025-08-28 The Regents Of The University Of California In vivo modification of cell genomes
WO2025255010A1 (en) * 2024-06-03 2025-12-11 X Development Llc Ai-guided synthetic biology development platform, systems, and methods

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KR20230110373A (ko) * 2016-06-14 2023-07-21 리전츠 오브 더 유니버스티 오브 미네소타 질환을 치료하기 위한 유전적으로 변형된 세포, 조직,및 장기
AU2020466994A1 (en) * 2019-09-17 2022-04-21 Rutgers, The State University Of New Jersey Highly efficient DNA base editors mediated by RNA-aptamer recruitment for targeted genome modification and uses thereof

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JP2024534720A (ja) 2024-09-25
EP4380627A1 (en) 2024-06-12
KR20240043783A (ko) 2024-04-03
WO2023015307A1 (en) 2023-02-09
AU2022324118A1 (en) 2024-02-22
CA3227964A1 (en) 2023-02-09
US20250109413A1 (en) 2025-04-03

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