CN118076372A - 治疗和预防肺病的组合物和方法 - Google Patents

治疗和预防肺病的组合物和方法 Download PDF

Info

Publication number
CN118076372A
CN118076372A CN202280061457.6A CN202280061457A CN118076372A CN 118076372 A CN118076372 A CN 118076372A CN 202280061457 A CN202280061457 A CN 202280061457A CN 118076372 A CN118076372 A CN 118076372A
Authority
CN
China
Prior art keywords
seq
peptide
asthma
purified peptide
therapeutic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280061457.6A
Other languages
English (en)
Chinese (zh)
Inventor
朱莉·莱德福德
莫妮卡·克拉夫特
约瑟夫·瓦格纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Redo LLC
Arizona's Public Universities
Original Assignee
Redo LLC
Arizona's Public Universities
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/409,642 external-priority patent/US20210379141A1/en
Application filed by Redo LLC, Arizona's Public Universities filed Critical Redo LLC
Priority claimed from PCT/US2022/075356 external-priority patent/WO2023028491A1/en
Publication of CN118076372A publication Critical patent/CN118076372A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN202280061457.6A 2021-08-23 2022-08-23 治疗和预防肺病的组合物和方法 Pending CN118076372A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17/409,642 2021-08-23
US17/409,642 US20210379141A1 (en) 2016-04-11 2021-08-23 Compositions and methods for treating and preventing lung disease
PCT/US2022/075356 WO2023028491A1 (en) 2021-08-23 2022-08-23 Compositions and methods for treating and preventing lung disease

Publications (1)

Publication Number Publication Date
CN118076372A true CN118076372A (zh) 2024-05-24

Family

ID=85278728

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280061457.6A Pending CN118076372A (zh) 2021-08-23 2022-08-23 治疗和预防肺病的组合物和方法

Country Status (6)

Country Link
EP (1) EP4392052A4 (https=)
JP (1) JP2024532412A (https=)
KR (1) KR20240052799A (https=)
CN (1) CN118076372A (https=)
AU (1) AU2022332283A1 (https=)
CA (1) CA3175945A1 (https=)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017180546A1 (en) * 2016-04-11 2017-10-19 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating and preventing lung disease
EP4132470A4 (en) * 2020-04-08 2023-11-08 Arizona Board of Regents on behalf of the University of Arizona COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF LUNG DISEASES

Also Published As

Publication number Publication date
AU2022332283A1 (en) 2024-03-07
CA3175945A1 (en) 2023-02-23
EP4392052A1 (en) 2024-07-03
JP2024532412A (ja) 2024-09-05
EP4392052A4 (en) 2025-07-23
KR20240052799A (ko) 2024-04-23

Similar Documents

Publication Publication Date Title
US11110152B2 (en) Compositions and methods for treating and preventing lung disease
JP7795489B2 (ja) Ｔｌｒアゴニストによる呼吸器感染症の治療
US20230190861A1 (en) Peptide therapeutics for acute and chronic airway and alveolar diseases
JP2010540654A5 (https=)
JP2005532988A (ja) 呼吸上皮の病変を治療するための方法および組成物
CN103200955A (zh) 包含肽和病毒神经氨酸酶抑制剂的组合物
US20240082342A1 (en) Peptide therapeutics for increasing lung cell viability
US20130281361A1 (en) Methods of treating and preventing rhinovirus infection
CN118076372A (zh) 治疗和预防肺病的组合物和方法
US20240269242A1 (en) Compositions and methods for treating and preventing lung disease
JP7783830B2 (ja) 肺疾患を治療及び予防するための組成物及び方法
EP4138891A1 (en) Peptides for the treatment of covid-19
WO2023028491A1 (en) Compositions and methods for treating and preventing lung disease
US20210379141A1 (en) Compositions and methods for treating and preventing lung disease
RU2737799C1 (ru) Ингаляционный гексапептид для лечения респираторных заболеваний, связанных с интерлейкином-6
JP2012505207A (ja) 慢性閉塞性肺疾患の予防用または治療用の薬剤組成物
JP2024539242A (ja) 慢性腎疾患の治療のための改変カベオリン－１ペプチド
WO2021211006A1 (en) Inhaled hexapeptide for treating interleukin-6 related respiratory diseases
US20230203095A1 (en) Biological peptide for treating lung diseases and application thereof
WO2024077042A2 (en) Il-1 receptor antagonist treatment for neutrophilic lung disease
US20220202700A1 (en) Compositions for the treatment of viral pulmonary infections
US20180344804A1 (en) Attenuation of intrapulmonary inflammation
WO1999064056A1 (en) Use of a cytokine regulatory agent to treat asthma

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination