CN118022203A - Boron neutron capture treatment device based on compact high-current proton RFQ accelerator - Google Patents

Abstract

The invention relates to the technical field of tumor treatment, in particular to a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator, which comprises a compact RFQ accelerator for generating and accelerating high-current proton beam current, a lithium target station system for converting the proton beam current into epithermal neutron beam, and a treatment room for accurate positioning of patients, accurate positioning of tumors and neutron irradiation. The treatment room accurately positions the patient through the seven-degree-of-freedom cantilever robot treatment chair system or the seven-degree-of-freedom cantilever robot treatment bed system, realizes the accurate positioning of the tumor of the patient through the slide rail CT image guiding system or the orthogonal X-ray image guiding system, and then accurately bombards the tumor containing boron medicine in the patient body by using the epithermal neutron beam to generate boron neutron capture reaction, releases alpha particles and lithium 7 particles to break the DNA double strand of the tumor cells, so that the tumor cells cannot be repaired and thoroughly die, thereby accurately killing the tumor and effectively inhibiting tumor recurrence.

Description

Boron neutron capture treatment device based on compact high-current proton RFQ accelerator

Technical Field

The invention relates to the technical field of tumor particle treatment, in particular to a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator.

Background

At present, the malignant tumor treatment has three major types of surgical operation treatment, chemical drug treatment, radiation treatment and the like. Radiation therapy kills tumor cells by ionizing radiation, but also produces a certain damage to surrounding normal tissues, and the damage is easy to cause toxic and side effects of radiotherapy. The long-term effects of radiation therapy are particularly important for pediatric patients, who once irreversibly damaged during the course of treatment will affect the quality of life of the child in terms of growth and development and adulthood. Therefore, the method improves the accuracy of tumor radiotherapy, reduces normal tissue injury and improves the life quality of patients, and is a development trend of radiotherapy in recent years. Of all malignant patients, 70% -80% are suitable for receiving radiation therapy. According to the statistics of world health organization, the cure rate of the tumor is up to 45%, and the radiation therapy contributes 22% to the cure rate of the tumor, so that the status and the effect of the radiation therapy in the tumor treatment can be seen.

Boron Neutron Capture Therapy (BNCT) belongs to one of radiation treatment means, and is mainly used for treating severe malignant tumors which are invasive, multiple, recurrent, radiation resistant and can not be well solved by the operation and radiotherapy and chemotherapy means. At present, the total number of relevant clinical cases is more than 2000, and the method has proved to have good curative effect for treating brain glioma, recurrent head and neck tumor, meningioma, malignant melanoma, liver metastasis cancer and other solid tumors; meanwhile, with the development of clinical researches on other types of tumors and the development of novel boron drugs in the global scope, the indications of the method are continuously increased, and the method is likely to become an ideal tumor treatment mode in the future. In addition to tumors, the method can be extended to other conditions such as Alzheimer's disease.

At present, two major types of technologies for realizing boron neutron treatment are internationally available, namely a neutron source realized based on a nuclear reactor is adopted, and the other type of technology is based on charged particle beams generated by an accelerator to bombard a target material to generate neutrons, wherein the accelerator-based technology mainly comprises three technical routes of an electrostatic accelerator, a cyclotron and a linear accelerator. RFQ accelerators are one type of linear accelerator commonly used.

The proton beam provided by the cyclotron has the characteristics of high energy and low flow intensity, so that the neutron energy generated by proton targeting is high, the volume of the moderator is huge, the generated epithermal neutron flux is relatively low, the treatment time is long, the fast neutrons and thermal neutrons are high, and the radiation level of the treatment room is high.

The proton beam provided by the electrostatic accelerator or the RFQ accelerator has the characteristics of low energy and high current intensity, so that the neutron energy generated by proton targeting is low, the volume of a neutron target station is small, the radiation level of a treatment room is low, and the proton beam is more suitable for clinical treatment.

The equipment of the electrostatic accelerator technology is easy to generate high-voltage ignition, so that the equipment is unstable in operation and the electronic equipment at a high-voltage end is easy to damage; the bremsstrahlung generated by the electrostatic accelerator in the operation process is high, so that the surrounding radiation level is high, and the difficulty in shielding equipment is increased; in addition, the divergence of the strong beam in the electrostatic accelerating tube can cause beam collapse, and new difficulties can be added to accelerator debugging.

The conventional proton RFQ accelerator has longer length, relatively higher construction cost, high electric loss and large electricity consumption during the operation of the accelerator, and relatively higher overall cost.

Disclosure of Invention

The invention aims to provide a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator, and aims to provide a patient positioning mode with multiple treatment postures, a tumor positioning mode guided by accurate images and a quick and accurate treatment plan making mode, so that more malignant tumors can be accurately and efficiently treated, and meanwhile, the space required by the accelerator can be fully compressed, and the cost is better reduced.

In order to achieve the above purpose, the invention provides a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator, which comprises a compact RFQ accelerator for generating and accelerating high-current proton beam, a lithium target station system for converting the proton beam into epithermal neutron beam, and a treatment room for accurate positioning of patients and accurate positioning of tumors and neutron irradiation; the lithium target station systems are provided with 2 lithium target station systems, one ends of the lithium target station systems are respectively connected with a proton accelerator, and the other ends of the lithium target station systems are connected with a treatment room system; the treatment room system comprises 2 treatment rooms, which are divided into a first treatment room and a second treatment room, and each treatment room is uniquely connected with the lithium target station system; the compact RFQ accelerator can generate high-current strong proton beam current; the lithium target station system can generate neutron beams after bombarding the lithium target station through proton beam current, and slow and reshape the neutron beams to generate epithermal neutrons which can be used for treatment; the treatment room adopts a seven-degree-of-freedom cantilever robot treatment couch system or a seven-degree-of-freedom cantilever robot treatment couch system to accurately position a patient, and adopts a slide rail CT image guiding system or an orthogonal X-ray image guiding system to accurately position tumors of the patient.

Wherein the proton beam energy is greater than 2.3 mev and the average current is greater than 10 ma.

Wherein the compact RFQ accelerator comprises a strong current ECR ion source, a low energy beam transmission line, a compact RFQ cavity and a high energy beam transmission line,

The strong current ECR ion source is used for generating direct current high current strong low energy proton beam current;

The low-energy beam transmission line is used for transmitting low-energy proton beam and injecting the low-energy proton beam into the compact RFQ cavity;

the compact RFQ cavity is used for accelerating proton beam from low energy to high energy, guaranteeing beam quality and controlling beam loss;

The high-energy beam transmission line is used for transmitting high-energy proton beams to the front end of the lithium target station system.

Wherein the compact RFQ cavity is no greater than 3 meters in length.

The first treatment room comprises a seven-degree-of-freedom cantilever robot treatment couch system and a sliding rail CT image guiding system, wherein the seven-degree-of-freedom cantilever robot treatment couch system is used for loading a patient and adjusting the position of the patient, the sliding rail CT image guiding system comprises a sliding rail unit arranged on the ground and CT equipment arranged on the sliding rail unit, and when the CT equipment works, the CT equipment moves from a parking position to a working position through the sliding rail unit; when the CT equipment completes work, the CT equipment moves back to the parking position through the sliding rail unit. The sliding rail CT image guiding system is used for accurately positioning tumors of a patient, adjusting the treatment position of the patient according to an image registration result, and moving the patient to a final treatment position by a sliding rail moving unit and a robot moving unit of the seven-degree-of-freedom cantilever robot treatment couch system.

The sliding rail CT image guiding system further comprises a CT radiation shielding door, wherein the CT radiation shielding door is used for shielding radiation of the CT equipment at a parking position when the CT equipment is not in operation.

The second treatment room comprises a seven-degree-of-freedom cantilever robot treatment chair system and an orthogonal X-ray image guiding system, the seven-degree-of-freedom cantilever robot treatment chair system is used for sitting and standing a patient and adjusting the position of the patient, the orthogonal X-ray image guiding system is used for accurately positioning tumors of the patient, then the adjustment is carried out according to an image registration result, and the patient is moved to a final treatment position by a sliding rail movement unit and a robot movement unit of the seven-degree-of-freedom cantilever robot treatment chair system.

Wherein the orthogonal X-ray image guidance system further comprises an X-ray radiation shielding gate for shielding radiation of orthogonal X-rays when not in operation.

The boron neutron capture treatment device based on the compact high-current proton RFQ accelerator further comprises a treatment planning system, wherein the treatment planning system is special for BNCT, and the treatment planning of the patient is formulated based on GPU rapid dose calculation and AI technology.

Wherein the treatment planning system comprises a machine data management unit, a patient image processing unit, a planning unit, a dose calculation engine, a plan evaluation unit, a plan output unit and a quality verification unit;

The machine data management unit is used for recording and managing treatment beam parameters and treatment device parameters;

The patient data management unit is used for recording and managing treatment information and image information of a patient to be treated, wherein the treatment information mainly comprises patient names, ages, head portraits, tumor positions and sizes, and the image information management mainly aims at realizing management among different image groups;

The patient image processing unit is used for delineating organs of a patient, comprises processing functions capable of adding and deleting treatment beds and is used for carrying out fusion correction processing functions on multiple images of the patient, wherein image data comprise PET-CT images, MR positioning images, CT positioning images and the like of the patient;

the planning unit is used for delineating a treatment target area of a patient according to the image data of the patient, ensuring the killing of tumor cells and avoiding or reducing the dose irradiation to normal tissues and organs at risk;

the dose calculation engine is used for calculating the irradiation dose distribution required by the patient according to a plan made by a medical physicist;

The plan evaluation unit is used for evaluating the expected treatment effect of the formulated plan and judging whether the plan can meet the clinical treatment target;

The plan output unit is used for generating an actual executable treatment scheme through the estimated and confirmed plan;

the quality verification unit is used for verifying the final plan executable and the dose distribution compliance.

The invention relates to a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator, which adopts the compact proton RFQ accelerator with the length not more than 3m to lead out proton beam with the energy more than 2.3 megaelectron volts and the average current more than 10 milliamperes, and the proton beam is conveyed to one or more target station systems through a high-energy beam conveying line, and a lithium target technology is adopted in a target station, and neutron beams are generated after the proton beam bombards the lithium target station, and the neutron beams are slowed down and shaped to generate epithermal neutron beams for treatment. During treatment, a patient is accurately positioned through the seven-degree-of-freedom cantilever robot treatment bed system or the seven-degree-of-freedom cantilever robot treatment chair system, the accurate positioning of the tumor of the patient is realized through the sliding rail CT image guiding system or the orthogonal X-ray image guiding system, the tumor which is rich in boron medicine in the patient body is accurately bombarded by using the epithermal neutron beam, the boron neutron capturing reaction occurs, and the two heavy ion rays of alpha particles and lithium 7 particles with the range of only about 10 micrometers are released, so that the DNA double strand of tumor cells is broken, the tumor cells cannot be repaired and thoroughly die, the tumor is accurately killed, and the tumor recurrence is effectively inhibited.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following description will briefly explain the embodiments or the drawings used in the description of the prior art, and it is obvious that the specific embodiments described herein are only for explaining the present invention, not limiting the present invention. It should be further noted that, for convenience of description, only some, but not all of the matters related to the present invention are shown in the accompanying drawings.

Fig. 1 is a block diagram of a boron neutron capture therapy device based on a compact high-current proton RFQ accelerator in accordance with a first embodiment of the invention.

Fig. 2 is a block diagram of the construction of a compact RFQ accelerator and lithium target station of a first embodiment of the invention.

Fig. 3 is a structural side view of a first treatment room of a first embodiment of the present invention.

Fig. 4 is a structural plan view of a second treatment room of the first embodiment of the present invention.

Fig. 5 is a logic diagram of a treatment planning system of a first embodiment of the present invention.

Compact RFQ accelerator 101, lithium target station 102, first treatment room 103, second treatment room 104, high current ECR ion source 105, low energy beam transmission line 106, compact RFQ cavity 107, high energy beam transmission line 108, seven degree of freedom cantilever robotic couch system 109, slide CT image guidance system 110, CT apparatus 111, slide rail unit 112, CT radiation shield door 113, orthogonal X-ray image guidance system 114, seven degree of freedom cantilever robotic couch system 115, treatment planning system 116, machine data management unit 117, patient data management unit 118, patient image processing unit 119, dose calculation engine 120, planning unit 121, plan evaluation unit 122, plan output unit 123, quality verification unit 124, X-ray radiation shield door 125.

Detailed Description

Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative and intended to explain the present invention and should not be construed as limiting the invention.

Referring to fig. 1 to 4, the present invention provides a boron neutron capture treatment device based on a compact high-current proton RFQ accelerator, which comprises a compact RFQ accelerator 101, two lithium target stations 102, a first treatment chamber 103 and a second treatment chamber 104, wherein the two lithium target stations 102 are connected with the compact RFQ accelerator 101, and the first treatment chamber 103 and the second treatment chamber 104 are respectively connected with the two lithium target stations 102; the compact RFQ accelerator 101 is configured to generate and accelerate a strong proton beam; the lithium target station 102 adopts a lithium target technology, generates neutron beams after bombarding the lithium target station by proton beam current, and is used for slowing down and shaping the neutron beams to generate epithermal neutrons for treatment, the first treatment room 103 realizes the accurate positioning of the tumor of a patient through the sliding rail CT image guiding system 110, and performs accurate positioning through the seven-degree-of-freedom cantilever robot treatment bed system 109, and then performs neutron treatment on the patient by using the epithermal neutron beams; the second treatment room 104 adopts an X-ray image guiding system 114 to conduct image guiding positioning on a patient, and conducts accurate positioning through a seven-degree-of-freedom cantilever robot treatment chair system 115, and then conducts neutron treatment on the patient through epithermal neutrons. In this embodiment, the BNCT treatment apparatus based on the compact high-current proton RFQ accelerator uses the compact proton RFQ accelerator with a length of not more than 3 meters to extract a proton beam with an energy of more than 2.3 mev and an average current of more than 10 milliamperes, and the proton beam is transported to one or more target station systems through the high-energy beam transport line 108, and the target station uses the lithium target technology, and the proton beam bombards the lithium target station 102 to generate a neutron beam, and slow and reshape the neutron beam to generate an epithermal neutron beam that can be used for treatment. During treatment, a patient is accurately positioned in a treatment room through the seven-degree-of-freedom cantilever robot treatment chair system 115 or the seven-degree-of-freedom cantilever robot treatment bed system 109, the accurate positioning of the tumor of the patient is realized through the slide rail CT image guiding system 110 or the orthogonal X-ray image guiding system 114, the tumor rich in boron medicine in the patient is accurately bombarded by using epithermal neutron beams, boron neutron capturing reaction occurs, and two heavy ion rays with the ranges of about 10 microns, namely alpha particles and lithium 7 particles, are released, so that the DNA double chains of tumor cells are broken, the tumor cells cannot be repaired and thoroughly die, the tumor is accurately killed, and the tumor recurrence is effectively inhibited.

The compact RFQ accelerator 101 includes a strong current ECR ion source 105, a low energy beam transmission line 106, a compact RFQ cavity 107, and a high energy beam transmission line 108, the strong current ECR ion source 105 for generating protons; the low-energy beam transmission line 106 is configured to transmit a low-energy particle beam and inject the low-energy particle beam into the compact RFQ cavity; the compact RFQ cavity 107 accelerates the proton beam from low energy to high energy, ensures beam quality, and controls beam loss; the high energy beam transport line 108 is used to transport the high energy particle beam to the lithium target station system. The ion source adopts an ECR electron cyclotron resonance ion source with GHz microwave frequency, proton beams are led out by high voltage and then are injected into an inlet of a compact RFQ cavity through a low-energy beam transmission line 106, and in the compact RFQ cavity with the length of not more than 3 meters, the beams are captured, focused, bunched and accelerated by a radio-frequency electromagnetic field to generate proton beams with energy of more than 2.3 megaelectron volts and average current of more than 10 milliamperes, and the proton beams are transported to one or more lithium target stations 102 through a high-energy beam transmission line 108.

The first treatment room 103 comprises a seven-degree-of-freedom cantilever robot treatment couch system 109 and a slide rail CT image guiding system 110, wherein the seven-degree-of-freedom cantilever robot treatment couch system 109 is used for loading a patient and adjusting the position, the slide rail CT image guiding system 110 comprises a slide rail unit 112 arranged on the ground and a CT device 111 arranged on the slide rail unit 112, and when the CT device 111 works, the CT device moves from a parking position to a working position through the slide rail unit 112; when the CT apparatus 111 completes the work, it moves back to the parking position by the slide rail unit 112. The slide rail CT image guidance system 110 is configured to accurately position a tumor of a patient, then adjust a treatment position of the patient according to an image registration result, and move the patient to a final treatment position by a slide rail motion unit and a robot motion unit of the seven-degree-of-freedom cantilever robot treatment couch system 109.

The slide rail CT image guidance system further comprises a CT radiation shielding door 113, the CT radiation shielding door 113 being used for shielding radiation of the CT apparatus 111 in a parking position when not in operation. In the treatment room, radiation shielding of the CT apparatus 111 when not in operation in a park position is required in order to avoid damage to the CT apparatus 111 by radiation due to the high neutron and gamma ray dose levels. A parking position which is disposed behind the CT radiation shield door 113 while the CT apparatus 111 is not in use at ordinary times; when image guiding positioning is needed, the CT radiation shielding door 113 is opened, the CT is moved to a working position through a sliding rail for image imaging, after the image guiding positioning is finished, the CT is moved back to a parking position of a radiation shielding area, and the CT radiation shielding door 113 is closed.

The second treatment room 104 includes an orthogonal X-ray image guidance system 114 and a seven-degree-of-freedom cantilever robotic treatment couch system 115, the seven-degree-of-freedom cantilever robotic treatment couch system 115 is used for sitting and standing a patient and adjusting positions, the orthogonal X-ray image guidance system 114 is used for performing image guidance positioning on the patient, then, according to the image registration result, the actual treatment position is adjusted, and the slide rail movement unit and the robot movement unit move the patient to the final treatment position. After a patient enters a treatment room, a treatment chair is placed at a patient upper stage position through a sliding rail movement unit and a robot movement unit; after the patient sits on the treatment chair, the patient is fixed on the treatment chair through the fixing device, and is moved to an image imaging position through the sliding rail moving unit and the robot moving unit, and the orthogonal X-ray image system 114 performs image guiding positioning on the patient; and then, according to the image registration result, the actual treatment position is adjusted, and the slide rail movement system and the robot movement system move the patient to the final treatment position to carry out treatment.

The orthogonal X-ray image guidance system further comprises an X-ray radiation shielding gate 125, the X-ray shielding gate 125 being used for shielding the X-ray system 114 from radiation when not in operation. In the treatment room, due to the high neutron and gamma ray dose levels, radiation shielding of the X-ray system 114 is required when not in operation in order to avoid damage to the X-ray system 114 from radiation. Closing the X-ray radiation shielding gate 125 when the X-ray system 114 is not in use at ordinary times; when image guided positioning is required, the X-ray radiation shielding door 125 is opened, the patient is positioned to the image position and imaged using the seven-degree-of-freedom cantilever robotic treatment couch system 115, and after image guided positioning is completed, the seven-degree-of-freedom cantilever robotic treatment couch system 115 is moved out and the X-ray radiation shielding door 125 is closed. The boron neutron capture therapy device based on the compact high-current proton RFQ accelerator further comprises a therapy planning system 116, wherein the therapy planning system 116 is special for BNCT, and the establishment of a patient therapy plan is realized based on GPU rapid dose calculation and AI technology.

The treatment planning system 116 includes a machine data management unit 117, a patient data management unit 118, a patient image processing unit 119, a dose calculation engine 120, a planning unit 121, a plan evaluation unit 122, a plan output unit 123, and a quality verification unit 124;

the machine data management unit 117 is responsible for recording and managing the treatment beam parameters and the treatment device parameters. These parameters are the basis of accurate irradiation, directly affecting the therapeutic effect and patient safety. Therefore, effective management of beam parameters and treatment device parameters is critical.

The patient data management unit 118 is responsible for recording and managing the treatment information and the image information of the patient being treated. The treatment information comprises patient name, age, head portrait, tumor position and size, and the image information mainly comprises patient PET-CT image, MR positioning image, CT positioning image, etc. This information provides an important basis for subsequent planning and evaluation.

The patient image processing unit 119 is responsible for patient organ delineation, while having processing functions that can add and delete treatment couch. In addition, it is responsible for fusion correction processing of multiple images of the patient to ensure accuracy of the treatment plan.

The dose calculation engine 120 is a core that automatically delineates the patient treatment target region from the patient image data. It ensures the killing effect on tumor cells, simultaneously reduces the dose irradiation to normal tissues and organs at risk as much as possible, and improves the safety and effectiveness of treatment.

The planning unit 121 is responsible for calculating the radiation dose distribution required for the patient according to the plan made by the medical physicist. The process needs to comprehensively consider various factors such as the illness state, the tumor characteristics, the treatment equipment and the like of the patient so as to realize personalized treatment.

The plan evaluation unit 122 is responsible for evaluating the expected treatment effect for the formulated plan and determining whether the plan can meet the clinical treatment objective. This link helps to find potential problems, adjust the treatment plan in advance, and ensure that the treatment proceeds smoothly.

The plan output unit 123 is responsible for generating an actual executable treatment plan from the estimated and confirmed plan. This procedure needs to ensure the feasibility of the plan and compliance of the dose distribution to ensure the safety and effectiveness of the treatment.

The quality verification unit 124 is responsible for quality control and verification of the overall treatment plan generation process. The quality and safety of the whole treatment process are ensured through monitoring links such as planning, evaluation, execution and the like.

In summary, the treatment planning system 116 enables rapid, accurate formulation and assessment of patient-specific treatment protocols through the cooperative operation of the various subsystems. This helps to improve the therapeutic effect, reduce adverse reactions, and provide safer and more efficient radiation therapy for patients.

The above disclosure is only a preferred embodiment of the present invention, and it should be understood that the scope of the invention is not limited thereto, and those skilled in the art will appreciate that all or part of the procedures described above can be performed according to the equivalent changes of the claims, and still fall within the scope of the present invention.

Claims (10)

1. A boron neutron capture treatment device based on a compact high-current proton RFQ accelerator comprises a compact RFQ accelerator, a lithium target station system and a treatment room, wherein the compact RFQ accelerator is used for generating and accelerating high-current proton beam current, the lithium target station system is used for converting the proton beam current into epithermal neutron beam, and the treatment room is used for accurate positioning of a patient, accurate positioning of tumors and neutron irradiation; the lithium target station system is provided with 2 lithium target stations, one ends of the lithium target station systems are respectively connected with the compact RFQ accelerator, and the other ends of the lithium target station systems are connected with the treatment room; the treatment rooms comprise 2 treatment rooms, and are divided into a first treatment room and a second treatment room, and each treatment room is uniquely connected with the lithium target station system; the method is characterized in that: the compact RFQ accelerator can generate high-current strong proton beam current; the lithium target station system can generate neutron beams after bombarding the lithium target station through proton beam current, and slow and reshape the neutron beams to generate epithermal neutrons which can be used for treatment; the treatment room adopts a seven-degree-of-freedom cantilever robot treatment couch system or a seven-degree-of-freedom cantilever robot treatment couch system to accurately position a patient, and adopts a slide rail CT image guiding system or an orthogonal X-ray image guiding system to accurately position tumors of the patient.

2. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The proton beam energy is greater than 2.3 mev and the average current is greater than 10 ma.

3. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The compact RFQ accelerator comprises a strong current ECR ion source, a low energy beam transmission line, a compact RFQ cavity and a high energy beam transmission line;

the strong current ECR ion source is used for generating direct current high current strong low energy proton beam current;

The low-energy beam transmission line is used for transmitting low-energy proton beam and injecting the low-energy proton beam into the compact RFQ cavity;

the compact RFQ cavity is used for accelerating proton beam from low energy to high energy, guaranteeing beam quality and controlling beam loss;

The high-energy beam transmission line is used for transmitting high-energy proton beams to the front end of the lithium target station system.

4. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The compact RFQ cavity is no greater than 3 meters in length.

5. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The first treatment room comprises a seven-degree-of-freedom cantilever robot treatment couch system and a sliding rail CT image guiding system, the seven-degree-of-freedom cantilever robot treatment couch system is used for loading a patient and adjusting the position, the sliding rail CT image guiding system comprises a sliding rail unit arranged on the ground and CT equipment arranged on the sliding rail unit, and when the CT equipment works, the CT equipment moves from a parking position to a working position through the sliding rail unit; when the CT equipment finishes working, the CT equipment moves back to the parking position through the sliding rail unit, the sliding rail CT image guiding system is used for accurately positioning the tumor of the patient, then the treatment position of the patient is adjusted according to the image registration result, and the patient is moved to the final treatment position by the sliding rail movement unit and the robot movement unit of the seven-degree-of-freedom cantilever robot treatment couch system.

6. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The slide rail CT image guidance system further comprises a CT radiation shielding door, wherein the CT radiation shielding door is used for shielding radiation of the CT equipment in a parking position when the CT equipment is not in operation.

7. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The second treatment room comprises a seven-degree-of-freedom cantilever robot treatment chair system and an orthogonal X-ray image guiding system, the seven-degree-of-freedom cantilever robot treatment chair system is used for sitting and standing a patient and adjusting the position of the patient, the orthogonal X-ray image guiding system is used for accurately positioning tumors of the patient, then adjusting the treatment position of the patient according to an image registration result, and the patient is moved to a final treatment position by a sliding rail movement unit and a robot movement unit of the seven-degree-of-freedom cantilever robot treatment chair system.

8. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The orthogonal X-ray image guidance system further includes an X-ray radiation shielding gate for shielding radiation of orthogonal X-rays when not in operation.

9. A boron neutron capture therapy device based on a compact high current proton RFQ accelerator as claimed in claim 1,

The boron neutron capture treatment device based on the compact high-current proton RFQ accelerator further comprises a treatment planning system, wherein the treatment planning system is special for BNCT, and the treatment planning of the patient is formulated based on GPU rapid dose calculation and AI technology.

10. The boron neutron capture therapy device of claim 9, wherein the boron neutron capture device is based on a compact high-current proton RFQ accelerator,

The treatment planning system comprises a machine data management unit, a patient image processing unit, a planning unit, a dose calculation engine, a plan evaluation unit, a plan output unit and a quality verification unit;

The machine data management unit is used for recording and managing treatment beam parameters and treatment device parameters;

The patient data management unit is used for recording and managing treatment information and image information of a patient to be treated, wherein the treatment information mainly comprises patient names, ages, head portraits, tumor positions and sizes, and the image information management mainly aims at realizing management among different image groups;

The patient image processing unit is used for delineating organs of a patient, comprises processing functions capable of adding and deleting treatment beds and is used for carrying out fusion correction processing functions on multiple images of the patient, wherein image data comprise PET-CT images, MR positioning images, CT positioning images and the like of the patient;

the planning unit is used for delineating a treatment target area of a patient according to the image data of the patient, ensuring the killing of tumor cells and avoiding or reducing the dose irradiation to normal tissues and organs at risk;

the dose calculation engine is used for calculating the irradiation dose distribution required by the patient according to a plan made by a medical physicist;

The plan evaluation unit is used for evaluating the expected treatment effect of the formulated plan and judging whether the plan can meet the clinical treatment target;

The plan output unit is used for generating an actual executable treatment scheme through the estimated and confirmed plan;

the quality verification unit is used for verifying the final plan executable and the dose distribution compliance.