CN118021880A - Traditional Chinese medicine composition and preparation method and application thereof - Google Patents

Traditional Chinese medicine composition and preparation method and application thereof Download PDF

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CN118021880A
CN118021880A CN202310509169.9A CN202310509169A CN118021880A CN 118021880 A CN118021880 A CN 118021880A CN 202310509169 A CN202310509169 A CN 202310509169A CN 118021880 A CN118021880 A CN 118021880A
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pain
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Sichuan Qingyitang Traditional Chinese Medicine Research Co ltd
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Sichuan Qingyitang Traditional Chinese Medicine Research Co ltd
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Abstract

The invention provides a traditional Chinese medicine composition, a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-20 parts of divaricate saposhnikovia root, 8-10 parts of mugwort leaf, 10-12 parts of safflower, 10-13 parts of frankincense, 10-15 parts of myrrh, 8-12 parts of lycopodium clavatum, 10-12 parts of cortex schizophragmatis integrifolii radicis, 8-10 parts of tobacco leaf, 10-12 parts of uncaria, 10-13 parts of aristolochia, 30-50 parts of aconite, 25-35 parts of nux vomica and 15-20 parts of agilawood. The invention can effectively relieve joint pain caused by rheumatism, has quick response and short treatment course, and can also relieve lower abdomen pain and distention symptom caused by dysmenorrhea. The preparation method is simple, does not damage human skin, and is suitable for clinical popularization and application.

Description

Traditional Chinese medicine composition and preparation method and application thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition, and a preparation method and application thereof.
Background
The common disease parts of the rheumatic bone diseases are mainly joints, including limb joints, spinal joints and the like. The Chinese medicine refers to the wind-damp bone disease as bone arthralgia, and in the "Su-Bi Lun": the wind, cold and dampness are mixed into arthralgia, namely, the arthralgia is caused by deficiency of healthy qi, deficiency of qi and blood and deficiency of wind-cold-dampness evil, and the wind, cold and dampness evil invade into human body to form arthralgia toxin and attach to bones of the human body, especially cartilage, so that the cartilage is damaged, and the bones and hard tissues related to the bones are damaged, thereby causing symptoms such as swelling, pain and paralysis of bones, muscles and tendons. Clinically, it mainly includes rheumatoid arthritis, lumbar disc herniation, hyperosteogeny of various parts of the body, pain occurring in the neck, shoulder or other joints, and is most common in orthopedics clinics.
The Western medicine adopts oral hormone medicine or analgesic for treating rheumatism bone diseases, and has only one effect and more adverse reactions. At present, the traditional Chinese medicine is used for treating the rheumatism bone diseases and is increasingly attracting attention. At present, the traditional Chinese medicine treatment mostly adopts the treatment methods of oral administration of traditional Chinese medicine and massage. Wherein, the oral administration of the traditional Chinese medicine is easy to cause stomach discomfort, and has poor compliance, so that the curative effect is difficult to be sustained. Although massage has the effect of relieving, it is difficult to cure the disease and the recurrence rate is high.
Therefore, the externally-applied traditional Chinese medicine composition can be directly adhered to the body surface, so that the active ingredients in the contained traditional Chinese medicine can permeate through the joint skin to reach the disease site, plays roles of relaxing tendons and dredging collaterals, activating qi-flowing, diminishing inflammation, dispelling cold, eliminating pathogenic factors and relieving pain, and has important significance for rapidly relieving the symptoms of the rheumatic joint pain of a patient.
Disclosure of Invention
In view of the above, the invention aims to provide a traditional Chinese medicine composition which can be prepared into an external medicament and can be directly used for rapidly relieving and/or treating uncomfortable symptoms caused by rheumatalgia in vitro.
In order to achieve the above object, the present invention provides the following technical solutions:
A traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-20 parts of divaricate saposhnikovia root, 8-10 parts of mugwort leaf, 10-12 parts of safflower, 10-13 parts of frankincense, 10-15 parts of myrrh, 8-12 parts of lycopodium clavatum, 10-12 parts of cortex schizophragmatis integrifolii radicis, 8-10 parts of tobacco leaf, 10-12 parts of uncaria, 10-13 parts of aristolochia, 30-50 parts of aconite, 25-35 parts of nux vomica and 15-20 parts of agilawood.
Preferably, the traditional Chinese medicine comprises the following raw materials in parts by weight: 16-18 parts of divaricate saposhnikovia root, 8.5-9 parts of mugwort leaf, 11-11.5 parts of safflower, 11-12 parts of frankincense, 12-13 parts of myrrh, 9-11 parts of lycopodium clavatum, 10.5-11 parts of cortex schizophragmatis integrifolii radicis, 8.5-9 parts of tobacco leaf, 11-11.5 parts of uncaria, 11-12 parts of aristolochia, 35-45 parts of aconite, 28-32 parts of nux vomica and 17-19 parts of agilawood.
Preferably, the traditional Chinese medicine comprises the following raw materials in parts by weight: 17 parts of divaricate saposhnikovia root, 9 parts of mugwort leaf, 11 parts of safflower, 11 parts of frankincense, 13 parts of myrrh, 10 parts of lycopodium clavatum, 11 parts of schizophragma integrifolium, 9 parts of tobacco leaf, 11 parts of uncaria, 12 parts of aristolochia, 42 parts of aconite, 30 parts of nux vomica and 18 parts of agilawood.
The invention also aims at providing an application of the traditional Chinese medicine composition in preparing medicines for treating and/or relieving rheumatalgia.
The invention also aims at providing an application of the traditional Chinese medicine composition in preparing medicines for treating and/or relieving dysmenorrhea.
Preferably, the rheumatic bone pain comprises rheumatic fever, rheumatic arthritis, rheumatoid arthritis, hyperosteogeny, scapulohumeral periarthritis, and prolapse of intervertebral disc.
Preferably, the medicament for treating and/or relieving the rheumatic bone pain and the medicament for treating and/or relieving the dysmenorrhea are externally applied medicaments.
The invention also aims to provide a preparation method of the external medicine, which comprises the following steps: weighing the raw materials according to a certain proportion, soaking, decocting, separating the medicinal liquid from the medicinal materials, drying the medicinal materials, breaking the wall to obtain medicinal powder, and mixing the medicinal liquid with the medicinal powder.
Preferably, during soaking, the ratio of raw material medicine to solution is 1:1.5g/mL, and soaking is carried out for 15-20min.
Preferably, the decoction is to firstly cook with strong fire and then cook with slow fire for 50-60min after the raw material medicines are soaked.
Compared with the prior art, the invention has the following beneficial effects:
The invention provides a traditional Chinese medicine composition, wherein aconite root is a medicine for tonifying fire and yang, restoring yang and rescuing collapse, dispelling cold and relieving pain, nux vomica is a monarch medicine for dispelling stasis and detumescence, dredging collaterals and relieving pain, and the two medicines are used as monarch medicines, so that the external cold and internal heat of the prescription are caused, and the effects of dredging channels and dispelling cold are achieved; the agilawood has the effects of promoting qi circulation to stop pain, warming middle energizer and relieving vomiting, absorbing qi and relieving asthma, preventing wind, dispelling wind, relieving exterior syndrome, eliminating dampness and relieving pain, relieving spasm, dispelling wind and removing dampness by lycopodium clavatum, relaxing tendons and activating collaterals, warming channels and dispelling cold and dampness by using artemisia leaf, dispelling dampness and relieving itching, promoting qi circulation and stopping pain by using tobacco leaves, eliminating dampness, detumescence, detoxification and disinsection, and promoting qi circulation by using five medicines, relieving pain, dispelling dampness and dispelling wind, and the five medicines are all ministerial medicines and auxiliary monarch medicines, so that the formula plays roles of warming and dredging channels and collaterals and dispelling rheumatism; safflower, flos carthami, dredging channels, removing stasis, relieving pain, olibanum, activating blood, relieving pain, detumescence, promoting granulation, myrrh, removing stasis, relieving pain, detumescence, promoting granulation, caulis Aristolochiae, promoting qi circulation, eliminating dampness, activating blood, relieving pain, expelling pathogenic wind, relaxing tendons, activating collaterals, expelling pathogenic wind, promoting blood circulation, ramulus Uncariae cum Uncis has effects of dispelling pathogenic wind, arresting convulsion, clearing heat, suppressing hyperactive liver, promoting blood circulation, relieving pain, activating qi-flowing, detumescence, coordinating and concocting, and can be used as adjuvant drug to make the formula have effects of promoting blood circulation, removing blood stasis, relieving pain and calming endogenous wind.
The traditional Chinese medicine composition provided by the invention has reasonable compatibility, and the medicines have synergistic effects, so that the whole formula has the effects of warming channels, relieving pain, detumescence, resolving hard mass, promoting blood circulation and removing blood stasis, can rapidly relieve symptoms such as soreness, tingling, swelling, stiffness, pain and inconvenience of joint parts of the rheumatic bone diseases, and can also relieve symptoms such as lower abdomen pain and distention caused by dysmenorrhea. The invention has the advantages of wide medicine source, convenient treatment, trouble saving, no adverse reaction and capability of avoiding the toxic and side effects of viscera caused by long-term oral administration of Chinese and western medicines by patients.
Detailed Description
The invention provides a traditional Chinese medicine composition, which comprises the following raw material medicines in parts by weight: 15-20 parts of divaricate saposhnikovia root, 8-10 parts of mugwort leaf, 10-12 parts of safflower, 10-13 parts of frankincense, 10-15 parts of myrrh, 8-12 parts of lycopodium clavatum, 10-12 parts of cortex schizophragmatis integrifolii radicis, 8-10 parts of tobacco leaf, 10-12 parts of uncaria, 10-13 parts of aristolochia, 30-50 parts of aconite, 25-35 parts of nux vomica and 15-20 parts of agilawood.
The traditional Chinese medicine composition preferably comprises the following raw materials in parts by weight: 16-18 parts of divaricate saposhnikovia root, 8.5-9 parts of mugwort leaf, 11-11.5 parts of safflower, 11-12 parts of frankincense, 12-13 parts of myrrh, 9-11 parts of lycopodium clavatum, 10.5-11 parts of cortex schizophragmatis integrifolii radicis, 8.5-9 parts of tobacco leaf, 11-11.5 parts of uncaria, 11-12 parts of aristolochia, 35-45 parts of aconite, 28-32 parts of nux vomica and 17-19 parts of agilawood. Further preferably, the medicine comprises the following raw materials in parts by weight: 17 parts of divaricate saposhnikovia root, 9 parts of mugwort leaf, 11 parts of safflower, 11 parts of frankincense, 13 parts of myrrh, 10 parts of lycopodium clavatum, 11 parts of schizophragma integrifolium, 9 parts of tobacco leaf, 11 parts of uncaria, 12 parts of aristolochia, 42 parts of aconite, 30 parts of nux vomica and 18 parts of agilawood.
The prepared aconite root has the effects of tonifying fire and yang, restoring yang and rescuing collapse, dispelling cold and relieving pain, and is used for treating yang deficiency and collapse, limb cold pulse, heart yang deficiency, chest stuffiness and pain, deficiency cold vomiting and diarrhea, epigastric cold pain, kidney yang deficiency, impotence, cold womb, yin cold edema, yang deficiency exogenous infection and cold dampness arthralgia; semen Strychni has effects of resolving hard mass, detumescence, dredging collaterals and relieving pain, and can be used for treating traumatic injury, fracture swelling and pain, rheumatism, numbness, paralysis, carbuncle, skin sore, and laryngopharynx swelling and pain; the two medicines are monarch medicines, so that the external cold and internal heat of the prescription can be realized, the effects of dredging channels and dispelling cold can be achieved, and the main effect of the prescription on symptoms can be realized.
The agilawood has the effects of promoting qi circulation, relieving pain, warming middle energizer, relieving vomiting, absorbing qi, relieving asthma, and promoting resuscitation, and can be used for treating chest and abdomen distention and pain, vomiting and hiccup due to stomach cold, and dyspnea due to kidney deficiency and adverse qi; radix Saposhnikoviae has effects of dispelling pathogenic wind, relieving exterior syndrome, eliminating dampness, relieving pain, and relieving spasm, and can be used for treating common cold, headache, rheumatalgia, rubella pruritus, tetanus, and severe fever due to internal heat and aversion to cold of rheumatism patients; the lycopodium clavatum has the effects of dispelling wind and removing dampness, relaxing tendons and activating collaterals, is used for treating arthralgia due to wind-cold-dampness, and is unfavorable in flexion and extension, and can effectively relieve the joint soreness; the mugwort leaf has the effects of warming channel to stop bleeding, dispelling cold to stop pain, dispelling dampness and relieving itching, and is mainly used for treating hematemesis, epistaxis, metrorrhagia, menorrhagia, lower abdomen cold pain, irregular menstruation, infertility caused by cold womb and external treatment of skin itch; the tobacco leaf has the effects of promoting qi circulation, relieving pain, eliminating dampness, detumescence, removing toxic substances, killing parasites, and is commonly used for food stagnation and fullness, pain due to qi stagnation, arthralgia, carbuncle, furuncle, mange, eczema, venomous snake bite, sprain and contusion, and has the effects of relaxing tendons and activating collaterals; the five medicaments are used as ministerial medicaments for promoting qi circulation, relieving pain, eliminating dampness and dispelling wind, and auxiliary monarch medicaments for enabling the formula to exert the effects of warming and activating meridians and dispelling rheumatism;
The safflower has the effects of promoting blood circulation, dredging channels, removing blood stasis and relieving pain, is used for treating amenorrhea, dysmenorrhea, lochia, chest stuffiness and pain, stasis and abdominal pain, chest and hypochondrium stabbing pain, traumatic injury and sore pain, has the effects of promoting blood circulation, removing blood stasis, removing dampness and removing swelling, and avoids pregnant women from using the medicine, otherwise, abortion can be caused; the frankincense has the effects of activating blood and relieving pain, and reducing swelling and promoting tissue regeneration, and is used for treating chest pain, epigastralgia, dysmenorrhea and amenorrhea, postpartum blood stasis and obstruction, abdominal pain, rheumatalgia, spasm of tendons and vessels, traumatic injury, carbuncle and swelling sore and ulcer; myrrh is used for removing blood stasis and relieving pain, reducing swelling and promoting tissue regeneration, and is used for treating chest pain, epigastralgia, dysmenorrhea and amenorrhea, postpartum blood stasis and obstruction, abdominal pain due to mass, rheumatalgia, traumatic injury, carbuncle swelling and sore and ulcer; the frankincense and the myrrh are medicines for strengthening blood circulation and relieving pain, and dredging collaterals and detumescence, and are mainly used for patients who need detumescence and granulation promotion, qi-flowing and pain relieving, blood circulation and blood stasis removing and general pain, and cold and dampness of liver channels and spleen channels; the caulis Aristolochiae has effects of promoting qi circulation, eliminating dampness, promoting blood circulation, relieving pain, inducing diuresis, and relieving swelling, and can be used for treating abdominal pain, arthralgia, and gestational edema; the Chinese medicinal composition has the effects of expelling wind, relaxing tendons, activating collaterals, dispelling wind, removing dampness, promoting blood circulation, regulating qi, relieving pain, and aiming at rheumatalgia and lumbar muscle strain; ramulus Uncariae cum Uncis has effects in calming endogenous wind, arresting convulsion, clearing heat, and suppressing hyperactive liver, and can be used for treating liver wind internal motion, convulsion, febrile convulsion, common cold, infantile convulsion, gestational eclampsia, headache, vertigo, lowering blood pressure, inhibiting platelet aggregation, and enhancing myocardial function; the six medicines are used as adjuvant drugs for activating blood, relieving pain, promoting qi circulation, detumescence and harmonizing compatibility, so that the prescription has the effects of activating blood, removing stasis, relieving pain and calming endogenous wind.
The traditional Chinese medicine composition disclosed by the invention has the effects of warming channels and relieving pain, detumescence and resolving hard mass, activating blood and dissolving stasis, and can warm and dredge 12 channels and collaterals, relieve pain, induce resuscitation, warm and supplement yang qi of five viscera and rapidly relieve symptoms such as tingling, sinking and expanding, stiffness, rigidity, pain and inconvenience of joint parts of the rheumatic bone diseases.
The invention also provides application of the traditional Chinese medicine composition in preparing medicines for treating and/or relieving rheumatalgia.
The invention also provides application of the traditional Chinese medicine composition in preparing medicines for treating and/or relieving dysmenorrhea. The traditional Chinese medicine composition can also effectively relieve lower abdomen pain and distention symptom caused by dysmenorrhea.
In the invention, the rheumatic bone pain comprises rheumatic fever, rheumatic arthritis, rheumatoid arthritis, hyperosteogeny, scapulohumeral periarthritis and prolapse of intervertebral disc.
In the invention, the medicine is an external medicine, and the medicine is preferably a plaster.
The invention also provides a preparation method of the external medicine, which comprises the following steps: weighing the raw materials according to a certain proportion, soaking, decocting, separating the medicinal liquid from the medicinal materials, drying the medicinal materials, breaking the wall to obtain medicinal powder, and mixing the medicinal liquid with the medicinal powder.
In the invention, the raw materials are weighed according to the proportion and then are uniformly mixed, and when in soaking, the ratio of the raw materials to the solution is 1:1.5g/mL, and the soaking is carried out for 15-20min. As one way of implementation, the present invention uses cold water soaking.
In the invention, after the soaking of the raw materials is finished, the raw materials are boiled with strong fire and then boiled with slow fire for 50-60min until the liquid medicine is 1/3-2/5 of the solution added during the soaking. The slow fire and the strong fire are Chinese medical nouns, and the normal operation in the field is adopted. Separating the medicinal liquid from the medicinal materials after the decoction is finished, drying the medicinal materials at 40-45 ℃, performing wall breaking treatment on the dried medicinal materials until the medicinal powder obtained by wall breaking is sieved by a 500-mesh sieve.
The preparation method of the plaster comprises the following steps:
Taking 3.5-4.5g of the mixture of the medicine liquid and the medicine powder, and spreading on non-woven fabrics to obtain the plaster.
In the invention, when the plaster is used, the affected part is ensured to be clean and dry, the plaster is directly stuck to the affected part, each time the plaster is stuck for 12-24 hours, and 3 days is a treatment course. The plaster of the invention is forbidden for allergic constitution, pregnant women and infants.
The external plaster prepared by the pharmaceutical composition can rapidly treat and/or relieve symptoms such as soreness, tingling, swelling, stiffness, pain and inconvenience of joint parts of the rheumatic bone diseases, has obvious curative effects on joint pain, swelling, stiffness and the like caused by rheumatic fever, rheumatic arthritis, rheumatoid arthritis, hyperosteogeny, scapulohumeral periarthritis, herniated disk and the like, and can also effectively relieve abdominal pain and distention caused by dysmenorrheal.
In the present invention, all raw material components are commercially available products well known to those skilled in the art unless specified otherwise.
The technical solutions provided by the present invention are described in detail below with reference to examples, but they should not be construed as limiting the scope of the present invention.
Example 1
A traditional Chinese medicine composition comprises the following raw materials in parts by weight: 17 parts of divaricate saposhnikovia root, 9 parts of mugwort leaf, 11 parts of safflower, 11 parts of frankincense, 13 parts of myrrh, 10 parts of lycopodium clavatum, 11 parts of schizophragma integrifolium, 9 parts of tobacco leaf, 11 parts of uncaria, 12 parts of aristolochia, 42 parts of aconite, 30 parts of nux vomica and 18 parts of agilawood.
Example 2
A traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15 parts of divaricate saposhnikovia root, 8 parts of mugwort leaf, 11 parts of safflower, 12 parts of frankincense, 12 parts of myrrh, 9 parts of lycopodium clavatum, 12 parts of schizophragma integrifolium, 10 parts of tobacco leaf, 11 parts of uncaria, 10 parts of aristolochia, 45 parts of aconite, 33 parts of nux vomica and 16 parts of agilawood.
Example 3
A traditional Chinese medicine composition comprises the following raw materials in parts by weight: 18 parts of divaricate saposhnikovia root, 9 parts of mugwort leaf, 12 parts of safflower, 11 parts of frankincense, 10 parts of myrrh, 12 parts of lycopodium clavatum, 11 parts of schizophragma integrifolium, 9 parts of tobacco leaf, 12 parts of uncaria, 13 parts of aristolochia, 48 parts of aconite, 32 parts of nux vomica and 19 parts of agilawood.
Example 4
A traditional Chinese medicine composition comprises the following raw materials in parts by weight: 17 parts of divaricate saposhnikovia root, 10 parts of mugwort leaf, 12 parts of safflower, 13 parts of frankincense, 14 parts of myrrh, 11 parts of lycopodium clavatum, 10 parts of schizophragma integrifolium, 8 parts of tobacco leaf, 12 parts of uncaria, 11 parts of aristolochia, 40 parts of aconite, 28 parts of nux vomica and 20 parts of agilawood.
Comparative example 1
The difference from example 1 is that: radix Aconiti lateralis Preparata and semen Strychni are not added.
Comparative example 2
The difference from example 1 is that: the agilawood, the divaricate saposhnikovia root and the tobacco leaves are not added.
Comparative example 3
The difference from example 1 is that: the safflower, the uncaria and the aristolochia are used in the replacement formula of sappan wood, gastrodia elata and radix Aristolochiae.
Example 5
In this example, the traditional Chinese medicine compositions in examples 1-4 and comparative examples 1-3 are prepared into plasters according to the following preparation methods:
Weighing the raw materials according to a proportion, soaking the raw materials in cold water for 20min according to a feed liquid ratio of 1:1.5 g/mL; boiling with strong fire and then decocting with slow fire for 60min until the liquid medicine is 1/3 of the solution added during soaking; separating the medicinal liquid from the medicinal materials, drying at 45deg.C, performing wall breaking treatment, sieving with 500 mesh sieve to obtain medicinal powder, and mixing the separated medicinal liquid with the medicinal powder;
taking 4.0g of the mixture of the medicine liquid and the medicine powder, and spreading on non-woven fabrics to obtain the plaster.
Patients with obvious rheumatalgia are selected as observation subjects, excluding those who cannot be regularly re-diagnosed. Wherein, 84 men and 126 women, the ages of the patients are 15-60 years, the patients are randomly divided into 7 groups, 4 patients with rheumatic joint pain, 5 patients with hyperosteogeny, 9 patients with lumbar muscle strain, 7 patients with cervical vertebra pain and 5 patients with scapulohumeral periarthritis.
The plaster prepared from the traditional Chinese medicine compositions of examples 1-4 and comparative examples 1-3 is applied to the affected part, 1 treatment course is carried out every 16h and 3 days, the curative effect is judged after 3 treatment courses, and the judgment standard is as follows: and (3) curing: the symptoms disappear and the activity returns to normal; the method is effective: the symptoms were markedly better, but still slightly uncomfortable; invalidation: the symptoms are not obviously improved. The effective rate was calculated as the sum of cure and effectiveness, and the results are shown in Table 1.
Table 1 effects of plaster prepared from different Chinese medicinal compositions on treating rheumatalgia
According to the results shown in Table 1, the plaster prepared from the traditional Chinese medicine composition provided by the invention has remarkable curative effect on rheumatic bone pain, and can rapidly relieve symptoms of pain, swelling and stiffness of an affected part. The medicines in the invention are reasonably compatible, have synergistic effect, are convenient to use and have no adverse effect.
Example 6
This example demonstrates the therapeutic effect of the Chinese medicinal composition after being prepared into a plaster on dysmenorrhea
The preparation method of the traditional Chinese medicine composition in the embodiment 1 is the same as that of the embodiment 5.
20 Cases of patients with dysmenorrhea symptoms are selected as observation objects, the ages of the patients are 14-28 years, the patients are primary dysmenorrhea, the plaster prepared from the traditional Chinese medicine composition of the embodiment 1 is stuck to an affected part on the first day of a physiological period, each plaster is stuck for 12h, 1 treatment course is taken for 3 days, and the curative effect is judged after 1 treatment course.
The plaster prepared from the traditional Chinese medicine composition has good curative effect on dysmenorrhea, the symptoms of lower abdomen pain of 13 patients are basically disappeared after 1 treatment course is applied to the plaster, the symptoms of lower abdomen pain of 5 patients are obviously relieved after 1 treatment course is applied to the plaster, the symptoms of lower abdomen pain of 2 patients are relieved after 1 treatment course, and the plaster still has uncomfortable feeling.
The clinical typical cases are as follows:
Case 1: xie Mou women, 27 years old, people in Mianyang city and scapulohumeral periarthritis patients, which are caused by common cold, have acute scapulohumeral periarthritis, are hard to pain and can not normally act, and are healed after 1 treatment course by using the plaster of the invention.
Case 2: zhang Mou men, 30 years old, people in Mianyang market, cervical vertebra pain, and the patients suffering from cervical and back pain for a long time are healed after 3 treatment courses of using the plaster of the invention.
Case 3: when a man, 32 years old, the man in Mianyang Jiang oil city, lumbar muscle strain, often caused by long-term sitting of work demands, is cured in 1 course of treatment.
Case 4: li Mou, women, 36 years old, mianyang Jiang oil city people, rheumatic arthritis pain mainly appears on the right elbow, and the pain is caused by long-term taking of a child and habituation of the child to sleep with the child's arms, and the plaster provided by the invention is used for curing 2 treatment courses.
Case 5: zhou Mou, women, 22 years old, adult cities, dysmenorrhea, particularly severe pain of lower abdomen in the first three days of physiological period, and intolerable pain symptoms after the plaster 1 is applied are obviously relieved, the plaster is applied for 1 treatment course each physiological period, 2 treatment courses are applied for two consecutive physiological periods, and pain symptoms are obviously relieved in the third physiological period, so that the plaster treatment is not needed any more.
Case 6: xie Mou women, 47 years old, yangjingjia, yangjia, the thick dam town of the city, knee joint hyperosteogeny, perennial farming, and the early symptoms of knee joint pain which are not considered important, so that pain is aggravated, and the plaster provided by the invention is used for curing 3 treatment courses.
The foregoing is merely a preferred embodiment of the present invention and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present invention, which are intended to be comprehended within the scope of the present invention.

Claims (10)

1. The traditional Chinese medicine composition is characterized by comprising the following raw materials in parts by weight: 15-20 parts of divaricate saposhnikovia root, 8-10 parts of mugwort leaf, 10-12 parts of safflower, 10-13 parts of frankincense, 10-15 parts of myrrh, 8-12 parts of lycopodium clavatum, 10-12 parts of cortex schizophragmatis integrifolii radicis, 8-10 parts of tobacco leaf, 10-12 parts of uncaria, 10-13 parts of aristolochia, 30-50 parts of aconite, 25-35 parts of nux vomica and 15-20 parts of agilawood.
2. The traditional Chinese medicine composition according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 16-18 parts of divaricate saposhnikovia root, 8.5-9 parts of mugwort leaf, 11-11.5 parts of safflower, 11-12 parts of frankincense, 12-13 parts of myrrh, 9-11 parts of lycopodium clavatum, 10.5-11 parts of cortex schizophragmatis integrifolii radicis, 8.5-9 parts of tobacco leaf, 11-11.5 parts of uncaria, 11-12 parts of aristolochia, 35-45 parts of aconite, 28-32 parts of nux vomica and 17-19 parts of agilawood.
3. The traditional Chinese medicine composition according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 17 parts of divaricate saposhnikovia root, 9 parts of mugwort leaf, 11 parts of safflower, 11 parts of frankincense, 13 parts of myrrh, 10 parts of lycopodium clavatum, 11 parts of schizophragma integrifolium, 9 parts of tobacco leaf, 11 parts of uncaria, 12 parts of aristolochia, 42 parts of aconite, 30 parts of nux vomica and 18 parts of agilawood.
4. Use of a traditional Chinese medicine composition according to any one of claims 1-3 for the preparation of a medicament for the treatment and/or alleviation of rheumatalgia.
5. Use of a traditional Chinese medicine composition according to any one of claims 1-3 for the preparation of a medicament for the treatment and/or alleviation of dysmenorrhoea.
6. The use according to claim 4, wherein the rheumatalgia comprises rheumatic fever, rheumatoid arthritis, hyperosteogeny, scapulohumeral periarthritis, disc herniation.
7. The use according to any one of claims 4-5, wherein the medicament is for external use.
8. The method for preparing an external medicine according to claim 7, comprising the steps of: weighing the raw materials according to a certain proportion, soaking, decocting, separating the medicinal liquid from the medicinal materials, drying the medicinal materials, breaking the wall to obtain medicinal powder, and mixing the medicinal liquid with the medicinal powder.
9. The method according to claim 8, wherein the ratio of the raw material medicine to the solution is 1:1.5g/mL, and the raw material medicine is soaked for 15-20min.
10. The preparation method according to claim 8, wherein the decoction is performed by boiling with strong fire and then decocting with slow fire for 50-60min after the raw materials are soaked.
CN202310509169.9A 2023-05-08 2023-05-08 Traditional Chinese medicine composition and preparation method and application thereof Pending CN118021880A (en)

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