CN117916228A - 内消旋丙交酯的纯化方法 - Google Patents

内消旋丙交酯的纯化方法 Download PDF

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Publication number
CN117916228A
CN117916228A CN202280061253.2A CN202280061253A CN117916228A CN 117916228 A CN117916228 A CN 117916228A CN 202280061253 A CN202280061253 A CN 202280061253A CN 117916228 A CN117916228 A CN 117916228A
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CN
China
Prior art keywords
lactide
meso
solvent
steps
meq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280061253.2A
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English (en)
Chinese (zh)
Inventor
约翰尼斯·杰基努斯·德·弗里斯
格里特·戈比乌斯·杜·萨特
维尔科·德·朗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purac Biochem BV
Original Assignee
Purac Biochem BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem BV filed Critical Purac Biochem BV
Publication of CN117916228A publication Critical patent/CN117916228A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
CN202280061253.2A 2021-09-10 2022-09-09 内消旋丙交酯的纯化方法 Pending CN117916228A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21195962 2021-09-10
EP21195962.2 2021-09-10
PCT/EP2022/075141 WO2023036948A1 (en) 2021-09-10 2022-09-09 Process for purifying meso-lactide

Publications (1)

Publication Number Publication Date
CN117916228A true CN117916228A (zh) 2024-04-19

Family

ID=77710639

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280061253.2A Pending CN117916228A (zh) 2021-09-10 2022-09-09 内消旋丙交酯的纯化方法

Country Status (6)

Country Link
US (1) US20240368110A1 (https=)
EP (1) EP4399205B1 (https=)
JP (1) JP7775450B2 (https=)
KR (1) KR20240055817A (https=)
CN (1) CN117916228A (https=)
WO (1) WO2023036948A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121666385A (zh) * 2023-08-03 2026-03-13 普拉克生化公司 处理丙交酯进料的方法
WO2025068252A1 (en) 2023-09-26 2025-04-03 Purac Biochem B.V. Process for manufacturing lactide
WO2026008344A1 (fr) 2024-07-02 2026-01-08 Futerro S.A. Procédé amélioré de production d'acide polylactique à faible indice de jaune

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5214159A (en) 1987-06-16 1993-05-25 Boehringer Ingelheim Gmbh Meso-lactide
WO1988010260A1 (fr) * 1987-06-16 1988-12-29 Boehringer Ingelheim Kg ''meso-lactide'' et son procede de preparation
NL8702563A (nl) 1987-10-28 1989-05-16 Cca Biochem B V Polymeer lactide, werkwijze voor het bereiden van een dergelijk polymeer lactide, alsmede een samenstelling, die een dergelijk polymeer lactide bevat.
BR9205956A (pt) 1991-04-29 1994-07-05 Paton H N Mola compósita, retanção para uma mola elastomérica tubular e sistema de suspensão de nivelamento de carga para um veículo
US5675021A (en) * 1992-03-19 1997-10-07 Chronopol, Inc. Method to produce and purify cyclic esters
US5686630A (en) * 1993-09-29 1997-11-11 Chronopol, Inc. Purifying cyclic esters by aqueous solvent extraction
US5463086A (en) * 1993-03-24 1995-10-31 Dainippon Ink And Chemicals, Inc. Process for producing lactides and process for purifying crude lactides
BE1018247A3 (fr) * 2008-08-14 2010-07-06 Futerro Sa Procede d'obtention de lactide.
EP2994462B2 (en) * 2013-05-06 2019-08-21 Futerro S.A. Process for recovering and improving production of meso-lactide from a crude lactide containing stream
CN105294644B (zh) * 2015-10-09 2018-10-16 中国科学院长春应用化学研究所 一种聚合级丙交酯的制备方法
RU2699801C1 (ru) * 2018-11-20 2019-09-11 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" (ТГУ, НИ ТГУ) Способ очистки лактида
CN113292531B (zh) * 2021-05-20 2023-09-26 重庆大学 一种meso-丙交酯和D,L-丙交酯的混合丙交酯的纯化方法

Also Published As

Publication number Publication date
JP7775450B2 (ja) 2025-11-25
US20240368110A1 (en) 2024-11-07
EP4399205A1 (en) 2024-07-17
KR20240055817A (ko) 2024-04-29
WO2023036948A1 (en) 2023-03-16
JP2024531592A (ja) 2024-08-29
EP4399205B1 (en) 2026-03-25

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