CN117881432A - 卟啉-氢卟啉化合物、包含其的组合物及其使用方法 - Google Patents

卟啉-氢卟啉化合物、包含其的组合物及其使用方法 Download PDF

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Publication number
CN117881432A
CN117881432A CN202280040999.5A CN202280040999A CN117881432A CN 117881432 A CN117881432 A CN 117881432A CN 202280040999 A CN202280040999 A CN 202280040999A CN 117881432 A CN117881432 A CN 117881432A
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CN
China
Prior art keywords
compound
porphyrin
group
hydroporphyrin
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280040999.5A
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English (en)
Chinese (zh)
Inventor
J·S·林赛
C·麦克内文
J·阿希贝
M·戈钦斯基
M·谷口
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nirvana Technology Co
North Carolina State University
Original Assignee
Nirvana Technology Co
North Carolina State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nirvana Technology Co, North Carolina State University filed Critical Nirvana Technology Co
Publication of CN117881432A publication Critical patent/CN117881432A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN202280040999.5A 2021-04-07 2022-04-07 卟啉-氢卟啉化合物、包含其的组合物及其使用方法 Pending CN117881432A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163171870P 2021-04-07 2021-04-07
US63/171870 2021-04-07
PCT/US2022/023827 WO2022216927A1 (en) 2021-04-07 2022-04-07 Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof

Publications (1)

Publication Number Publication Date
CN117881432A true CN117881432A (zh) 2024-04-12

Family

ID=83545711

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280040999.5A Pending CN117881432A (zh) 2021-04-07 2022-04-07 卟啉-氢卟啉化合物、包含其的组合物及其使用方法

Country Status (6)

Country Link
US (1) US20250295815A1 (https=)
EP (1) EP4319823A4 (https=)
JP (1) JP2024514848A (https=)
CN (1) CN117881432A (https=)
CA (1) CA3213957A1 (https=)
WO (1) WO2022216927A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119101058A (zh) * 2024-09-03 2024-12-10 徐州医科大学 一种用于生物成像与声动力治疗的卟啉化合物及其制备方法与应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116519116B (zh) * 2023-03-30 2024-06-21 苏州大学 一种掺杂型锌铜压电声敏剂及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420648B1 (en) * 2000-07-21 2002-07-16 North Carolina State University Light harvesting arrays
US20100016208A1 (en) * 2005-11-15 2010-01-21 The General Hospital Corporation Photoactivatable antimicrobial agents
ES2707228T3 (es) * 2008-09-18 2019-04-03 Biolitec Unternehmensbeteiligungs Ii Ag Nuevo método y aplicación de porfirinas y clorinas asimétricamente meso-sustituidas para TFD
US20110275686A1 (en) * 2009-12-11 2011-11-10 Biolitec, Inc. Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)
CN105396135B (zh) * 2015-12-15 2019-03-15 青龙高科技股份有限公司 靶向性多肽修饰的铁蛋白纳米颗粒装载卟啉二聚体盐复合物及其用途和制备方法
WO2017214637A1 (en) * 2016-06-10 2017-12-14 Nirvana Sciences Inc. Hydroporphyrin beads with narrow fluorescence emissions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119101058A (zh) * 2024-09-03 2024-12-10 徐州医科大学 一种用于生物成像与声动力治疗的卟啉化合物及其制备方法与应用

Also Published As

Publication number Publication date
EP4319823A4 (en) 2025-04-23
CA3213957A1 (en) 2022-10-13
WO2022216927A9 (en) 2023-09-14
WO2022216927A1 (en) 2022-10-13
JP2024514848A (ja) 2024-04-03
EP4319823A1 (en) 2024-02-14
US20250295815A1 (en) 2025-09-25

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