CA3213957A1 - Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof - Google Patents

Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof Download PDF

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Publication number
CA3213957A1
CA3213957A1 CA3213957A CA3213957A CA3213957A1 CA 3213957 A1 CA3213957 A1 CA 3213957A1 CA 3213957 A CA3213957 A CA 3213957A CA 3213957 A CA3213957 A CA 3213957A CA 3213957 A1 CA3213957 A1 CA 3213957A1
Authority
CA
Canada
Prior art keywords
compound
hydroporphyrin
porphyrin
optionally
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3213957A
Other languages
English (en)
French (fr)
Inventor
Jonathan S. Lindsey
Christopher Macnevin
Joshua Akhigbe
Michael GORCZYNSKI
Masahiko Taniguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nirvana Sciences Inc
North Carolina State University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA3213957A1 publication Critical patent/CA3213957A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA3213957A 2021-04-07 2022-04-07 Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof Pending CA3213957A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163171870P 2021-04-07 2021-04-07
US63/171,870 2021-04-07
PCT/US2022/023827 WO2022216927A1 (en) 2021-04-07 2022-04-07 Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof

Publications (1)

Publication Number Publication Date
CA3213957A1 true CA3213957A1 (en) 2022-10-13

Family

ID=83545711

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3213957A Pending CA3213957A1 (en) 2021-04-07 2022-04-07 Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof

Country Status (6)

Country Link
US (1) US20250295815A1 (https=)
EP (1) EP4319823A4 (https=)
JP (1) JP2024514848A (https=)
CN (1) CN117881432A (https=)
CA (1) CA3213957A1 (https=)
WO (1) WO2022216927A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116519116B (zh) * 2023-03-30 2024-06-21 苏州大学 一种掺杂型锌铜压电声敏剂及其制备方法与应用
CN119101058B (zh) * 2024-09-03 2025-09-12 徐州医科大学 一种用于生物成像与声动力治疗的卟啉化合物及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420648B1 (en) * 2000-07-21 2002-07-16 North Carolina State University Light harvesting arrays
US20100016208A1 (en) * 2005-11-15 2010-01-21 The General Hospital Corporation Photoactivatable antimicrobial agents
ES2707228T3 (es) * 2008-09-18 2019-04-03 Biolitec Unternehmensbeteiligungs Ii Ag Nuevo método y aplicación de porfirinas y clorinas asimétricamente meso-sustituidas para TFD
US20110275686A1 (en) * 2009-12-11 2011-11-10 Biolitec, Inc. Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)
CN105396135B (zh) * 2015-12-15 2019-03-15 青龙高科技股份有限公司 靶向性多肽修饰的铁蛋白纳米颗粒装载卟啉二聚体盐复合物及其用途和制备方法
WO2017214637A1 (en) * 2016-06-10 2017-12-14 Nirvana Sciences Inc. Hydroporphyrin beads with narrow fluorescence emissions

Also Published As

Publication number Publication date
EP4319823A4 (en) 2025-04-23
CN117881432A (zh) 2024-04-12
WO2022216927A9 (en) 2023-09-14
WO2022216927A1 (en) 2022-10-13
JP2024514848A (ja) 2024-04-03
EP4319823A1 (en) 2024-02-14
US20250295815A1 (en) 2025-09-25

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Class et al. Inventors: Jonathan S. Lindsey (Raleigh, NC, US) Michael Krayer (Raleigh, NC, US) Assignees: North Caroliina State University

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