CN117740676A - Photometry device and sample analyzer - Google Patents

Photometry device and sample analyzer Download PDF

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Publication number
CN117740676A
CN117740676A CN202311718077.8A CN202311718077A CN117740676A CN 117740676 A CN117740676 A CN 117740676A CN 202311718077 A CN202311718077 A CN 202311718077A CN 117740676 A CN117740676 A CN 117740676A
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CN
China
Prior art keywords
assembly
carrier
light measuring
reaction cup
photometry
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Application number
CN202311718077.8A
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Chinese (zh)
Inventor
甘裕明
鲍茂然
王海
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Medcaptain Medical Technology Co Ltd
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Medcaptain Medical Technology Co Ltd
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Publication date
Application filed by Medcaptain Medical Technology Co Ltd filed Critical Medcaptain Medical Technology Co Ltd
Priority to CN202311718077.8A priority Critical patent/CN117740676A/en
Publication of CN117740676A publication Critical patent/CN117740676A/en
Pending legal-status Critical Current

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Abstract

The application provides a photometry device and sample analyzer relates to check out test set technical field. The light measuring device comprises a base, a light measuring assembly, a mixing assembly and a driving assembly, wherein the driving assembly is connected with the bearing piece to drive the bearing piece to carry out mixing operation, so that samples placed in a reaction cup at the bearing position of the reaction cup can be fully mixed. The driving component can also drive the bearing piece to relatively displace with the photometry component, so that the bearing position of the reaction cup is opposite to the photometry component, a sample placed in the reaction cup at the bearing position of the reaction cup can be opposite to the photometry component, and the photometry component can carry out photometry detection on the uniformly mixed sample. Therefore, a mechanism for carrying out uniform mixing operation on the bearing piece and a mechanism for driving the bearing position of the reaction cup to be opposite to the light measuring assembly are not required to be arranged separately, so that the number of parts of the light measuring device can be reduced, and the structure of the light measuring device is more compact.

Description

Photometry device and sample analyzer
Technical Field
The application relates to a photometry device and sample analyzer, belongs to check out test set technical field.
Background
The chemiluminescence analysis technology can directly or indirectly carry out quantitative and qualitative analysis on inorganic compounds and organic compounds, so that the method has high sensitivity and selectivity and is widely applied. Fluorescence analysis techniques can specifically collect fluorescence data by PMT (photomultiplier tube) detection devices.
In the related art, the sample to be detected processed by the magnetic separation device has the problem of uneven distribution, if the sample to be detected processed by the magnetic separation device is directly detected by PMT detection equipment, the detection result of the sample to be detected will be inaccurate.
Disclosure of Invention
The application provides a photometry device and a sample analyzer, which solve the problem that the detection result of a sample to be detected by PMT detection equipment in the related technology is inaccurate.
In a first aspect, the present application provides a photometry device comprising:
a base;
the light measuring assembly is arranged on the base;
the mixing assembly comprises a movable bearing piece, and at least one reaction cup bearing position is arranged on the bearing piece;
the driving assembly is arranged on the base, the output end of the driving assembly is connected with the bearing piece, the driving assembly drives the bearing piece to carry out uniform mixing operation, and drives the bearing piece or the photometry assembly to move, so that the bearing position of the reaction cup is opposite to the photometry assembly.
In some embodiments, the bearing member is further provided with a light measuring channel, one end of the light measuring channel is communicated with the bearing position of the reaction cup, and the other end of the light measuring channel is an opening formed in the side wall of the bearing member.
In some embodiments, the mixing assembly further comprises a housing, a detection bin is arranged in the housing, the bearing piece is located in the detection bin, a detection port is formed in the side wall of the housing, and the photometry assembly is located at the detection port.
In some embodiments, the blending assembly further comprises a cover removably attached to the opening of the detection bin.
In some embodiments, the cover plate is provided with a reaction cup taking and placing opening, and the driving assembly is configured to drive the bearing piece to rotate until the reaction cup bearing position is opposite to the reaction cup taking and placing opening.
In some embodiments, the blending operation includes reciprocating along a straight line or a curve.
In some embodiments, the drive assembly includes a drive member, an output end of the drive member being coupled to the carrier member to drive rotation of the carrier member.
In some embodiments, the driving assembly further comprises a transmission member, the driving member and the bearing member are located on the same side of the base, the transmission member is located on one side of the base away from the bearing member, an input end of the transmission member is connected with the driving member, and an output end of the transmission member is connected with the bearing member.
In some embodiments, the driving assembly includes a first driving member and a second driving member, the first driving member drives the carrier member to perform a blending operation, and the second driving member drives the carrier member or the photometry assembly to move.
In a second aspect, the present application provides a sample analyzer comprising a photometry device as described above
In the photometry device and the sample analyzer provided by the application, the reaction cup bearing position on the bearing piece can be used for bearing the reaction cup, and the sample to be detected by the light can be placed in the reaction cup; the driving component is connected with the bearing piece to drive the bearing piece to carry out uniform mixing operation, so that samples in the reaction cup placed in the bearing position of the reaction cup can be fully mixed. The driving component can also drive the bearing piece to relatively displace with the light measuring component, so that the bearing position of the reaction cup is opposite to the light measuring component, a sample placed in the reaction cup at the bearing position of the reaction cup can be opposite to the light measuring component, and the light measuring component can perform light measuring detection on the uniformly mixed sample, so that the light measuring detection result of the sample is more accurate. This application is integrated in the photometry device with mixing subassembly and photometry subassembly, can no longer need set up the mixing device alone to reducible sample analysis appearance's part quantity makes sample analysis appearance's structure compacter.
Drawings
The foregoing and other objects, features and advantages of embodiments of the present application will become more readily apparent from the following detailed description, which proceeds with reference to the accompanying drawings. Embodiments of the present application will now be described, by way of example and not limitation, in the figures of the accompanying drawings, in which:
FIG. 1 is a schematic diagram of a photometry device according to an embodiment of the present application;
FIG. 2 is a schematic diagram of a detection end of a light measuring assembly of a light measuring device according to an embodiment of the present disclosure opposite to a bearing position of a reaction cup;
FIG. 3 is a schematic diagram of a calibration end of a calibration assembly of a photometry device and a detection end of the photometry assembly according to an embodiment of the present application;
fig. 4 is a schematic diagram of a driving assembly of the photometry device according to the embodiment of the present application.
Reference numerals:
100-the base, 110-the leg,
200-mixing components, 210-a shell, 211-a detection bin, 220-a bearing piece, 221-a reaction cup bearing position, 222-a rotating shaft, 223-a photometry channel, 224-a calibration channel, 230-a cover plate, 231-an input opening, 232-a reaction cup taking and placing opening, 240-a reaction cup,
300-calibration assembly, 310-reference light source section, 320-fiber optic line, 321-calibration end,
400-photometry component, 410-detection end,
500-drive assembly, 510-drive member, 520-transmission member,
600-an excitation liquid component, wherein the excitation liquid component,
700-lifting member.
Detailed Description
Embodiments of the present application are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and intended for the purpose of explaining the present application and are not to be construed as limiting the present application.
In the description of the present application, it should be understood that the terms "center," "longitudinal," "transverse," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," etc. indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, are merely for convenience in describing the present application and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be configured and operated in a particular orientation, and therefore should not be construed as limiting the present application.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present application, the meaning of "plurality" is at least two, such as two, three, etc., unless explicitly defined otherwise.
In this application, unless specifically stated and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the terms in this application will be understood by those of ordinary skill in the art as the case may be.
In this application, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present application. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the different embodiments or examples described in this specification and the features of the different embodiments or examples may be combined and combined by those skilled in the art without contradiction.
The chemiluminescence analysis technology can directly or indirectly carry out quantitative and qualitative analysis on inorganic compounds and organic compounds, so that the method has high sensitivity and selectivity and is widely applied. Chemiluminescent analysis techniques can specifically collect fluorescence data by PMT (photomultiplier tube) detection devices.
In the related art, the sample to be detected processed by the magnetic separation device has the problem of uneven distribution, if the sample to be detected processed by the magnetic separation device is directly detected by PMT detection equipment, the detection result of the sample to be detected will be inaccurate.
In the photometry device and the sample analyzer that this application provided, mixing subassembly and photometry subassembly all set up in the base for mixing subassembly and photometry subassembly can be fixed. The reaction cup bearing position on the bearing piece can be used for bearing a reaction cup, and a sample to be detected by light can be placed in the reaction cup. The driving component is connected with the bearing piece to drive the bearing piece to carry out uniform mixing operation, so that samples in the reaction cup placed in the bearing position of the reaction cup can be fully mixed. The driving component can also drive the bearing piece to relatively displace with the light measuring component, so that the bearing position of the reaction cup is opposite to the light measuring component, a sample placed in the reaction cup at the bearing position of the reaction cup can be opposite to the light measuring component, and the light measuring component can perform light measuring detection on the uniformly mixed sample, so that the light measuring detection result of the sample is more accurate. This application is integrated in the photometry device with mixing subassembly and photometry subassembly, can no longer need set up the mixing device alone to reducible sample analysis appearance's part quantity makes sample analysis appearance's structure compacter.
The photometry device and the sample analyzer provided by the present application will be described in detail with reference to specific embodiments.
Referring to fig. 1 to 3, the light measuring device provided in the present application includes a base 100, a mixing assembly 200, a light measuring assembly 400, and a driving assembly 500. The photometry device can be used for carrying out photometry detection on a sample, and can be applied to a sample analyzer.
Wherein the base 100 is a base member of the light measuring device of the present application, the base 100 may provide a mounting base for at least some other components of the light measuring device. The mixing assembly 200 is disposed on the base 100, a reaction cup bearing position 221 is disposed on the mixing assembly 200, a sample to be detected may be disposed on the reaction cup bearing position 221, specifically, the sample to be detected may be disposed in a container such as a reaction cup 240, and a container such as the reaction cup 240 may be disposed on the reaction cup bearing position 221 of the mixing assembly 200.
The photometry assembly 400 is disposed on the base 100, and the detection end 410 of the photometry assembly 400 is located at one side of the mixing assembly 200, the photometry assembly 400 is specifically a photomultiplier assembly, and the photometry assembly 400 can directly or indirectly perform quantitative and qualitative analysis on a sample to be detected by using a fluorescence analysis technology. Specifically, the light measuring assembly 400 has a detection end 410, and the detection end 410 of the light measuring assembly 400 can receive a signal emitted by a sample to be detected. Specifically, by mixing the sample to be detected with the excitation liquid, the sample to be detected may generate a weak optical signal, and the detection end 410 of the light measurement assembly 400 may receive the optical signal generated by the sample to be detected and compare the optical signal with the signal in the database, so as to analyze the sample to be detected.
At least part of the mixing assembly 200 is movably connected with the base 100, specifically, the mixing assembly 200 includes a carrier 220, the carrier 220 is movably connected with the base 100, and a reaction cup bearing position 221 is located on the carrier 220. The driving assembly 500 is disposed on the base 100, and the driving assembly 500 is connected to the carrier 220, so that the driving assembly 500 can drive the carrier 220 to move relative to the base 100, thereby driving the cuvette carrier 221 disposed on the carrier 220 to move relative to the base 100, and changing the relative positional relationship between the cuvette carrier 221 and the base 100. The driving assembly 500 may drive the carrier 220 to perform a mixing operation, specifically, the driving assembly 500 may drive the carrier 220 to reciprocate, and at this time, the sample in the cuvette 240 located at the cuvette loading position 221 may also reciprocate along with the carrier 220, so that the sample in the cuvette 240 may shake, so that the sample may be sufficiently mixed. This allows for a more consistent cost content for each portion of the sample.
The driving assembly 500 may further drive the cuvette carrier 221 of the carrier 220 to face the detecting end 410 of the photometry assembly 400, and if the cuvette 240 loaded with the sample to be detected is placed in the cuvette carrier 221, the cuvette 240 loaded with the sample to be detected may face the detecting end 410 of the photometry assembly 400, so that the sample to be detected may face the detecting end 410 of the photometry assembly 400, and at this time, the photometry assembly 400 is started to perform photometry detection on the sample to be detected.
When the photometry device is applied to detect a sample to be detected, the driving assembly 500 can drive the carrying member 220 of the mixing assembly 200 to move, so that the carrying member 220 performs mixing operation, and the sample in the reaction cup 240 can be fully mixed. After the samples are sufficiently mixed, the driving assembly 500 drives the carrier 220 of the mixing assembly 200 to displace relative to the photometry assembly 400, so that the cuvette carrying position 221 of the carrier 220 is opposite to the detection end 410 of the photometry assembly 400, and thus the sample to be detected in the cuvette 240 of the cuvette carrying position 221 of the carrier 220 can be opposite to the detection end 410 of the photometry assembly 400, so as to complete the detection of the sample to be detected.
In addition, a driving component 500 may be further disposed in transmission connection with the light measuring component 400, where the driving component 500 drives the light measuring component 400 to move, so that the light measuring component 400 moves relative to the reaction cup bearing position 221 on the bearing member 220, and the detection end 410 of the light measuring component 400 is opposite to the reaction cup bearing member 221.
In some embodiments, referring to fig. 1 to 3, a rotating disc structure may be adopted for a carrier 220 of the mixing assembly 200 of the present application, the carrier 220 may be rotatably connected with the base 100, and correspondingly, the reaction cup bearing positions 221 may be distributed on the carrier 220 at positions other than the positions rotationally connected with the base 100, so that after the carrier 220 rotates, the reaction cup bearing positions 221 may be displaced relative to the rotation center of the carrier 220, a motor may be adopted for the driving assembly 500, and an output end of the motor is connected with the carrier 220 to drive the carrier 220 to rotate. In the process of rotating the bearing member 220, the reaction cup 240 placed at the reaction cup bearing position 221 can rotate along with the bearing member 220 relative to the rotation center of the bearing member 220, so that the sample in the reaction cup 240 can shake under the centrifugal force, and the sample can be uniformly mixed. The driving assembly 500 drives the carrier 220 to rotate, and can rotate the sample to be detected placed at the cuvette carrying position 221 to be opposite to the detecting end 410 of the photometry assembly 400, so that the well-mixed sample can be subjected to photometry detection.
Specifically, the rotational connection portion between the carrier 220 and the base 100 may be disposed at the central portion of the carrier 220, the reaction cup bearing 221 is offset from the central portion of the mixing component 200, and the driving component 500 drives the carrier 220 to rotate at different angles so that the reaction cup bearing 221 is opposite to the detection end 410 of the photometry component 400. The driving assembly 500 drives the carrier 220 to rotate at different rotation speeds and different rotation durations, so that the samples in the reaction cup 240 have different mixing effects. Specifically, the faster the drive assembly 500 drives the carrier 220 to rotate, the more thoroughly the sample within the cuvette 240 can be mixed. The longer the drive assembly 500 is to drive the carrier 220 to rotate, the more thoroughly the sample within the cuvette 240 can be mixed. The driving assembly 500 may further drive the carrier 220 to rotate a certain number of turns along the first direction and then rotate a certain number of turns along the second direction, where the first direction and the second direction are opposite to each other, so that the sample has a better mixing effect.
In addition, in other embodiments, the carrier 220 of the present application may also be configured to be movably coupled to the base 100 such that the carrier 220 may reciprocate relative to the base 100. Specifically, the base 100 and the carrier 220 may be provided with a matched guiding structure, the guiding structure may limit the carrier 220 to move along a linear direction, the driving assembly 500 may drive the carrier 220 to reciprocate along a third direction or a fourth direction, and the third direction and the fourth direction may be opposite to each other, so that the sample in the reaction cup 240 may shake, and the sample may be uniformly mixed. The light measuring assembly 400 is disposed at one side of the carrier 220, and the driving assembly 500 drives the carrier 220 to move along a linear direction, so that the carrier 220 can also move to a position where the reaction cup carrying position 221 is opposite to the detecting end 410 of the light measuring assembly 400. The drive assembly 500 may also be configured to drive the carrier 220 back and forth along the fold line, which may also allow for uniform mixing of the sample within the cuvette 240.
Specifically, the blending operation in the present application includes reciprocating movement along a straight line or a curved line, and when the driving assembly 500 implements the blending operation by driving the carrier 220 to rotate or swing, the number of times that the driving assembly 500 drives the carrier 220 to rotate or swing along the first direction or the second direction may be set to 300 to 800 times per minute, so that the sample may be fully blended. When the driving assembly 500 drives the carrier 220 to reciprocate along the linear direction, the number of times that the driving assembly 500 drives the carrier 220 to move along the third direction or the fourth direction may be set to 300 to 800 times per minute, so that the samples can be sufficiently mixed.
In some embodiments, referring to fig. 1 to 3, the mixing assembly 200 of the present application may further include a housing 210, wherein the housing 210 may be fixedly disposed on the base 100, the housing 210 has a detection chamber 211 therein, and the carrier 220 is disposed in the detection chamber 211 of the housing 210. The carrier 220 is connected to the driving assembly 500, and the driving assembly 500 can drive the carrier 220 to rotate. When the bearing member 220 is in a disc structure, correspondingly, the detection bin 211 of the housing 210 is in a cylindrical cavity structure, and the outer edge of the bearing member 220 can be in contact with the inner wall of the housing 210 or has a smaller gap, so that the inner wall of the housing 210 can play a role in limiting the bearing member 220 when the driving assembly 500 drives the bearing member 220 to rotate, and the rotation precision of the bearing member 220 is higher.
The bearing piece 220 is disposed in the housing 210, so that the housing 210 covers the reaction cup bearing position 221 of the mixing assembly 200, a detection opening through which the light measuring assembly 400 passes can be formed in the sidewall of the housing 210, the detection end 410 of the light measuring assembly 400 can extend into the housing 210 through the detection opening of the housing 210, and both the sample to be detected disposed in the reaction cup bearing position 221 and the detection end 410 of the light measuring assembly 400 are disposed in the detection bin 211 of the housing 210. When the light measuring assembly 400 performs light measuring detection on a sample to be detected and the driving assembly 500 drives the carrier 220 to shake uniformly, the detection and shaking-up processes are both implemented in the housing 210, the housing 210 can shield external light to a certain extent, so that interference of the external light on the detection result of the sample to be detected is reduced, the detection precision of the sample to be detected is higher, and the sample in the reaction cup 240 can be prevented from being scattered outside the housing 210 in the shaking-up process.
The bottom end of the housing 210 may be disposed on the base 100, the top end of the housing 210 is provided with an opening communicating with the detection bin 211 of the housing 210 and a movable cover plate 230, the cover plate 230 may seal the opening at the top end of the housing 210, or the cover plate 230 is separated from the opening at the top end of the housing 210, so that the opening of the housing 210 is in an open state, and after the cover plate 230 of the housing 210 is opened, a user may also perform maintenance on the carrier 220 and the detection end 410 of the photometry assembly 400 disposed in the housing 210. The cover 230 of the housing 210 may be rotatably connected to the housing 210, specifically may be hinged and fastened by a snap fit.
In this application, the reaction cup bearing position 221 on the bearing member 220 may be specifically configured to be a groove structure formed on the bearing member 220, and the reaction cup 240 for loading to be detected may be placed in the reaction cup bearing position 221 of the bearing member 220, where the opening of the reaction cup bearing position 221 is located at the top of the reaction cup bearing position 221. The cuvette carrier 221 of the carrier 220 may be disposed adjacent to an edge of the carrier 220, the sidewall of the carrier 220 may further be provided with a photometric channel 223 communicating with the cuvette carrier 221, the carrier 220 may be rotated to position the photometric channel 223 thereon between the detection end 410 of the photometric component 400 and the cuvette carrier 221, so that the cuvette carrier 221 and the detection end 410 may communicate with each other, and the detection end 410 of the photometric component 400 may be opposite to the cuvette carrier 221, so that the photometric component 400 may be opposite to the cuvette 240 disposed in the cuvette carrier 221, and the photometric component 400 may detect a sample to be detected in the cuvette 240.
In addition, the reaction cup bearing position 221 on the bearing member 220 may not be provided with a groove structure, and the reaction cup 240 is fixed on the reaction cup bearing position 221 on the surface of the bearing member 220 through a fixing structure, so that the whole reaction cup 240 is located on the bearing member 220, and thus the detection end 410 of the light measuring assembly 400 may be directly opposite to the reaction cup 240, so as to perform light measurement detection on the sample in the reaction cup 240.
In some embodiments, referring to fig. 1 to 3, the light measuring device of the present application may further include a calibration component 300, where the calibration component 300 may emit calibration light, and in particular, the calibration component 300 has a calibration end 321, the calibration component 300 may emit calibration light through the calibration end 321, the calibration end 321 of the calibration component 300 is disposed in the housing 100, and the calibration end 321 of the calibration component 300 may be disposed opposite to the detection end 410 of the light measuring component 400. The calibration channel 224 can be disposed on the carrier 220, and the carrier 220 can be rotated until the calibration channel 224 is located between the calibration end 321 and the detection end 410, and at this time, the calibration end 321 is directly opposite to the detection end 410, and there is no shielding between the calibration end 321 and the detection end 410, so that the calibration assembly 300 can calibrate the photometry assembly 400, and the photometry detection result of the photometry assembly 400 on the sample is more accurate.
The calibration assembly 300 in the present application includes a reference light source portion 310 and an optical fiber line 320, wherein the reference light source portion 310 is a main component of the calibration assembly 300, and the reference light source portion 310 can generate reference light. One end of the optical fiber 320 may be connected to the output end of the reference light source 310, and the other end of the optical fiber 320 is the calibration end 321 of the calibration assembly 300, so that the other end of the optical fiber 320 may be disposed through the housing 210 and extend into the housing 210 and be fixed in the housing 210. One end of the alignment channel 224 forms an opening in the sidewall of the carrier 220. The driving assembly 500 drives the carrier 220 to rotate, such that the calibration channel 224 of the carrier 220 is located between the calibration end 321 and the detection end 410, and thus the calibration end 321 and the detection end 410 can communicate, such that the calibration end 321 is opposite to the detection end 410, and the light emitted by the calibration end 321 can pass through the calibration channel 224 and be received by the detection end 410.
The arrangement of the optical fiber line 320 can make the arrangement of the calibration end 321 of the calibration assembly 300 more flexible, so that the main body reference light source part 310 of the calibration assembly 300 can be omitted from being arranged on the carrier 220, thereby reducing the weight of the components carried on the carrier 220, and correspondingly, the overall weight of the components required to be driven by the driving assembly 500 is relatively smaller, so that the driving assembly 500 does not need to adopt a large driving force and a large power model, and the cost of the photometry device of the application can be reduced.
In some embodiments, referring to fig. 4, the driving assembly 500 of the present application may include a driving member 510 and a transmission member 520, where the driving member 510 is connected to the carrier 220 through the transmission member 520, so that the driving member 510 may drive the carrier 220 to rotate through the transmission member 520, and the driving member 510 is connected to the carrier 220 through the transmission member 520, so that direct contact between the driving member 510 and the carrier 220 can be avoided, and loss of the output end of the driving member 510 is reduced. The transmission member 520 may have a pulley structure, specifically, the transmission member 520 may include a first pulley, a second pulley, and a rotating belt, the bearing member 220 may be provided with a rotating shaft 222, the rotating shaft 222 may extend out of the housing 210, the first driving wheel is connected to an output end of the driving member 510, the second driving wheel is connected to the rotating shaft 222, and the driving belt is sleeved on the first driving wheel and the second driving wheel. When the driving member 510 drives the first driving wheel to rotate, the second driving wheel can be driven by the driving belt, so that the bearing member 220 can rotate.
Of course, the transmission member 520 may also adopt a gear structure, and specifically, the transmission member 520 may include a first gear and a second gear, where the first gear is connected to the output end of the driving member 510, the second gear is connected to the rotating shaft 222, and the first gear and the second gear are meshed. The driving member 510 drives the first gear to rotate and then drives the second gear to rotate, so that the carrier 220 can rotate.
According to the light measuring device, the driving piece 510 is connected with the bearing piece 220 to drive the bearing piece 220 to move, so that samples can be uniformly mixed, the reaction cup bearing position 221 can be rotated to be opposite to the detection end 410 of the light measuring assembly 400, light measuring detection of the samples is completed, namely, the driving piece 510 drives the bearing piece 220 to move, and light measuring detection and uniform mixing operation can be achieved. Therefore, the number of components of the driving assembly 500 can be reduced, so that the driving assembly 500 is compact in structure, and the photometry device of the application is compact in structure.
In some embodiments, the drive assembly 500 of the present application may further include two drive members 510, the two drive members 510 being a first drive member and a second drive member, respectively. Wherein the first driving member may be coupled to the carrier 220, and the second driving member may be coupled to the photometry assembly 400. The second driving member can drive the light measuring assembly 400 to move until the detection end 410 of the light measuring assembly 400 is opposite to the carrier 220, the first driving member can drive the carrier 220 to perform mixing operation, and the second driving member can drive the light measuring assembly 400 to rotate or move relative to the carrier 220. So that the detection end 410 of the photometry assembly 400 is opposite to the cuvette loading site 221 of the carrier 220. The first driving member can drive the carrier 220 to reciprocate so that the samples can be uniformly mixed.
Furthermore, in other embodiments, the first driving member may be configured to be coupled to the second driving member, and the second driving member may be configured to be coupled to the carrier 220. The first driving member can drive the second driving member to move to the reaction cup 240, where the carrier 220 is opposite to the detection end 410 of the photometry assembly 400. The second driving member can drive the carrying member 220 to rotate so that the samples in the cuvette 240 can be uniformly mixed. When the first driving member and the second driving member are started at the same time, the carrying member 220 can be driven to reciprocate along the linear direction and rotate around the connection position of the carrying member 220 and the second driving member, so that the sample in the reaction cup 240 has better mixing effect.
In some embodiments, referring to fig. 1 to 3, in order to further make the light measuring device of the present application compact, it may be achieved by fully utilizing the available installation space on the base 100. Specifically, the blending assembly 200 may be disposed on the upper side of the base 100, the driving member 510 may be disposed on the upper side of the base 100 and located on one side of the blending assembly 200, and the driving member 520 may be disposed on one side of the bottom of the base 100, so that the driving member 520 and the driving member 510 are disposed on opposite sides of the base 100, and the driving member 520 and the blending assembly 200 are also disposed on opposite sides of the base 100, so that both opposite sides of the base 100 may be used for installing components of the light measuring device, and accordingly, the surface area of one side of the base 100 may not need to be too large, so that the base 100 and the light measuring device of the application have compact structure.
Specifically, the driving member 510 may be disposed upside down to the base 100, where the output end of the driving member 510 is disposed through the base 100 and extends to the bottom side of the base 100, and the rotating shaft 222 is also disposed through the base 100 and extends to the bottom side of the base 100, so that the driving member 520 disposed at the bottom side of the base 100 is connected to both the output end of the driving member 510 and the rotating shaft 222.
Referring to fig. 1 and 4, a foot 110 may be disposed at the bottom of the base 100, wherein the foot 110 may support the base 100, and the driving member 510, the mixing assembly 200, and the photometry assembly 400 may be disposed at a side of the base 100 facing away from the foot 110.
In some embodiments, referring to fig. 1 to 3, the photometry device of the present application may further include an excitation liquid piece 600, where the excitation liquid piece 600 may input an excitation liquid to a sample to be detected, so that a detection result of the photometry assembly 400 after detecting the sample to be detected is clearer and more accurate. The excitation liquid piece 600 has an excitation liquid output end, and the excitation liquid piece 600 can output excitation liquid through the excitation liquid output end, and the excitation liquid piece 600 can be disposed on one side of the top of the cover plate 230, so that the excitation liquid output end is also disposed on one side of the top of the cover plate 230. The cover plate 230 is provided with an input opening 231, and the input opening 231 of the cover plate 230 is opposite to the excitation liquid output end of the excitation liquid piece 600, so that the excitation liquid output by the excitation liquid output end falls into the reaction cup 240 in the housing 210 through the input opening 231 of the cover plate 230.
When the driving assembly 500 drives the carrier 220 to rotate, the driving assembly 500 can also drive the carrier 220 to rotate until the cuvette carrier 221 is opposite to the input opening 231, so that the excitation liquid falls into the sample to be detected in the housing 210 through the input opening 231 and can fall into the cuvette carrier 221, so that the excitation liquid can be mixed with the sample to be detected.
The top opening of the cuvette 240 may be positioned near the input opening 231 of the housing 210 such that the excitation liquid may more accurately fall into the cuvette 240 for mixing with the sample to be tested after falling into the housing 210 through the input opening 231.
The casing 210 may further be provided with a cuvette pick-and-place opening 232, and the cuvette 240 loaded with the sample to be detected may be inserted into the cuvette loading position 221 of the carrier 220 through the cuvette pick-and-place opening 232 of the casing 210, and specifically, the driving assembly 500 may drive the carrier 220 to rotate to the cuvette loading position 221 opposite to the cuvette pick-and-place opening 232.
In some embodiments, referring to the figures and the drawings, in order to enable the excitation liquid output by the excitation liquid component 600 to be injected into the reaction cup 240 more accurately and mixed with the sample to be detected, the photometry device of the present application may further include a lifting component 700, where the lifting component 700 is connected to the excitation liquid component 600, and the lifting component 700 is configured to drive the excitation liquid output end of the excitation liquid component 600 to move toward the base 100 or back to the base 100. When the carrier 220 rotates to the reaction cup bearing position 221 opposite to the input opening 231 of the cover 230, the lifting member 700 drives the excitation liquid output end of the excitation liquid member 600 to move toward the base 100, so that the excitation liquid output end is close to the input opening 231 of the cover 230. The lifting member 700 continues to drive the excitation liquid output end to move towards the base 100, so that the excitation liquid output end extends into the housing 210 through the input opening 231 of the cover plate 230 until the excitation liquid output end extends into the reaction cup 240, and then the excitation liquid member 600 can inject the excitation liquid into the reaction cup 240 through the excitation liquid output end. This ensures that the excitation liquid output from the excitation liquid member 600 falls completely into the cuvette 240 to be mixed with the sample to be detected, preventing the excitation liquid from being scattered outside the cuvette 240. After the injection of the excitation liquid into the reaction cup 240 is completed, the driving component 500 drives the carrier 220 to shake uniformly, so that the excitation liquid and the sample can be fully mixed, and the photometric component 400 detects the sample to be detected after the mixing operation is completed.
After the operation of injecting the excitation liquid into the reaction cup 240 by the excitation liquid piece 600 is completed, the lifting piece 700 can drive the excitation liquid piece 600 to move along the direction opposite to the base 100, so that the excitation liquid output end of the excitation liquid piece 600 moves out of the reaction cup 240 and out of the housing 210, and thus the excitation liquid output end of the excitation liquid piece 600 cannot interfere with the turntable.
Based on the light metering device, the embodiment of the application also provides a sample analyzer, which comprises the light metering device.
Finally, it should be noted that: the above embodiments are merely for illustrating the technical solution of the present application, and are not limiting thereof; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced with equivalents; such modifications and substitutions do not depart from the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present application.

Claims (10)

1. A photometry device, comprising:
a base;
the light measuring assembly is arranged on the base;
the mixing assembly comprises a movable bearing piece, and at least one reaction cup bearing position is arranged on the bearing piece;
the driving assembly is arranged on the base, the output end of the driving assembly is connected with the bearing piece, the driving assembly drives the bearing piece to carry out uniform mixing operation, and drives the bearing piece or the photometry assembly to move, so that the bearing position of the reaction cup is opposite to the photometry assembly.
2. The light measuring device of claim 1, wherein the carrier is further provided with a light measuring channel, one end of the light measuring channel is communicated with the bearing position of the reaction cup, and the other end of the light measuring channel is an opening formed in the side wall of the carrier.
3. The light measuring device of claim 1, wherein the blending assembly further comprises a housing, a detection bin is disposed in the housing, the carrier is disposed in the detection bin, a detection port is disposed on a side wall of the housing, and the light measuring assembly is disposed at the detection port.
4. A light measuring device as recited in claim 3, wherein the blending assembly further comprises a cover plate detachably connected to the opening of the detection chamber.
5. The light measuring device of claim 4, wherein the cover plate is provided with a cuvette pick-and-place opening, and the driving assembly is configured to drive the carrier to rotate to a position where the cuvette is carried opposite to the cuvette pick-and-place opening.
6. The light metering device of any of claims 1-5 wherein the blending operation comprises a reciprocating motion along a straight line or a curved line.
7. The light measuring device of any one of claims 1-5, wherein the drive assembly comprises a drive member, an output end of the drive member being coupled to the carrier member to drive the carrier member to rotate.
8. The light measuring device of claim 7, wherein the drive assembly further comprises a transmission member, the drive member and the carrier member are located on the same side of the base, the transmission member is located on a side of the base away from the carrier member, an input end of the transmission member is connected with the drive member, and an output end of the transmission member is connected with the carrier member.
9. The light measurement device of any one of claims 1-5, wherein the drive assembly comprises a first drive member that drives the carrier for a blending operation and a second drive member that drives the carrier or the light measurement assembly.
10. A sample analyzer comprising a photometry device according to any one of claims 1-9.
CN202311718077.8A 2023-12-13 2023-12-13 Photometry device and sample analyzer Pending CN117740676A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311718077.8A CN117740676A (en) 2023-12-13 2023-12-13 Photometry device and sample analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311718077.8A CN117740676A (en) 2023-12-13 2023-12-13 Photometry device and sample analyzer

Publications (1)

Publication Number Publication Date
CN117740676A true CN117740676A (en) 2024-03-22

Family

ID=90258610

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311718077.8A Pending CN117740676A (en) 2023-12-13 2023-12-13 Photometry device and sample analyzer

Country Status (1)

Country Link
CN (1) CN117740676A (en)

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