CN117694257A - Programmable animal experiment box for simulating special environment - Google Patents
Programmable animal experiment box for simulating special environment Download PDFInfo
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- CN117694257A CN117694257A CN202410057028.2A CN202410057028A CN117694257A CN 117694257 A CN117694257 A CN 117694257A CN 202410057028 A CN202410057028 A CN 202410057028A CN 117694257 A CN117694257 A CN 117694257A
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Abstract
The invention discloses a programmable animal experiment box for simulating a special environment, which comprises a test box, a cabinet and a transparent box, wherein the test box is arranged on the cabinet; a sealed experimental space is formed inside the test box; a camera, a lighting device, a temperature sensor, a humidity sensor, a noise detector, a loudspeaker, a carbon dioxide detector and an oxygen detector are fixedly arranged on the top wall of the inner side of the box body; the transparent box is arranged in the box body and is provided with a vent hole, a small door and a hanging device; a water tank and a food tank are arranged in the transparent box; the cabinet is provided with a controller, a control panel, a display screen and a status indicator lamp; the controller is used for controlling the switch of the camera and the lighting device according to the control instruction and controlling the temperature, humidity, brightness, noise intensity, carbon dioxide concentration and oxygen concentration in the box body. The programmable animal experiment box has the characteristics of multiple controllable environmental factors, high control precision and capability of being observed in real time.
Description
Technical Field
The invention relates to the technical field of animal experiment boxes, in particular to a programmable animal experiment box for simulating a special factor environment.
Background
The lack of ergonomic conditions in industrial systems not only compromises the occupational health of the operators, but also directly affects production efficiency and quality. Studies have shown that the occurrence of certain psychological disorders is closely related to professional environments, such as anxiety and depression occurrence in the population of mining personnel, blasting personnel, flight personnel, and submarines, are significantly upregulated. Under the special environment, common adverse environmental factors include high temperature, high humidity, air pollution, darkness, noise, narrow space and the like, and the psychological and physiological health of operators are seriously influenced by repeated times or long-time exposure to the special working environment. In studying the influence of the specific environment on human health, animal models play an important role in addition to directly studying humans. Under the background, on the basis of carrying out system research and analysis on the special environment, the inventor develops a simulated closed cabin composite environment device capable of simultaneously providing gas environment, temperature, humidity, noise, illumination and real-time observation, and simultaneously completing the environment simulation function of a plurality of animals.
Disclosure of Invention
The invention provides a programmable animal experiment box for simulating a special environment, which has the characteristics of multiple controllable environment factors, high control precision and real-time observation, can simultaneously simulate gas environment, temperature, humidity, noise, illumination and microgravity, can realize fine parameter adjustment on the environment factors, and can realize real-time monitoring of an animal model and the environment.
The invention adopts the following specific technical scheme:
a programmable animal experiment box for simulating a special environment, which is used for rodents and experimental monkeys and comprises a test box, a cabinet and a transparent box;
the test box comprises a box body and a box door rotatably arranged at one side of the box body, and a sealed experiment space is formed in the box body by closing the box door; a camera, a lighting device, a temperature sensor, a humidity sensor, a noise detector, a loudspeaker, a carbon dioxide detector and an oxygen detector are fixedly arranged on the top wall of the inner side of the box body; the carbon dioxide detector is used for detecting the concentration of carbon dioxide in the box body; the oxygen detector is used for detecting the oxygen concentration in the box body; the noise detector is used for detecting the noise intensity in the box body; the temperature sensor is used for detecting the temperature in the box body; the humidity sensor is used for detecting the humidity in the box body; an air outlet is formed in the top wall of the box body, an air return opening is formed in the rear side wall of the box body, a test hole is formed in the side wall of the box body, and a water outlet is formed in the bottom wall of the box body;
the transparent box is placed in the box body and is provided with a vent hole communicated with the experimental space and a small door which is opened outwards; a water tank and a food tank are arranged in the transparent box;
the cabinet is provided with a controller, a control panel, a display screen and a status indicator lamp; the controller is in signal connection with the camera, the lighting device, the temperature sensor, the humidity sensor, the noise detector, the loudspeaker, the carbon dioxide detector, the oxygen detector, the control panel, the display screen and the status indicator lamp; the control panel and the display screen are used for inputting control instructions; the display screen is used for displaying control information; the state indicator lamp is used for indicating the running state of the test box; the controller is used for controlling the switch of the camera and the lighting device according to the control instruction and controlling the temperature, the humidity, the brightness, the noise intensity, the carbon dioxide concentration and the oxygen concentration in the box body.
Still further, the air conditioner also comprises a heating device, a refrigerating device, a humidifying device, an air bottle and an adjustable air deflector;
the heating device is arranged in the test box and used for increasing the temperature in the box;
the refrigerating device comprises an evaporator arranged in the test box and a condenser arranged in the cabinet and is used for reducing the temperature in the box;
the humidifying device is arranged in the test box and used for improving the humidity in the box body;
the gas cylinder is communicated with the test box through a pipeline and is used for introducing carbon dioxide, oxygen and nitrogen into the box body of the test box;
an electromagnetic valve in signal connection with the controller is arranged in the pipeline, and the concentration of carbon dioxide and the concentration of oxygen in the box body are adjusted by controlling the electromagnetic valve;
the adjustable air deflector is arranged in the box body and used for improving the uniformity of temperature and humidity distribution.
Still further, the cabinet is provided with a noise generator and an audio power amplifier;
the noise generator is in signal connection with the loudspeaker through the audio power amplifier; the noise generator adopts a transistor vibration circuit for generating sine wave signals, and directly drives the loudspeaker to sound after being amplified by the audio power amplifier.
Still further, the control panel is provided with a buzzer for emitting a prompt tone, a power button for controlling a power switch, a speed regulation button for regulating a noise frequency, a reset button for restoring an original state, an emergency stop button for emergency stop, and an overtemperature protector for setting an upper limit of temperature in the experimental space.
Further, a hanging device for hanging the tail is arranged on the top of the transparent box.
Furthermore, the suspension device is a cross rod or a tail suspension chain and is used for carrying out tail suspension on rodents and simulating the microgravity effect. .
Further, the experimental space of the test box is a cuboid cavity, and the size is 1000mm multiplied by 800mm multiplied by 1000mm;
the transparent box is made of acrylic materials and is of a cube-shaped structure with the side length of 200-600 mm;
the height and the width of the small door are 100-400 mm;
the bottom of the transparent box is provided with a fecal collecting device;
the aperture of the vent hole is 10mm.
Further, the wall of the box body and the box door comprise an inner plate, an outer plate and a heat insulation material clamped between the inner plate and the outer plate;
the inner plate is a 304 stainless steel plate with the thickness of 1 mm;
the outer plate is a double-sided galvanized steel plate with the thickness of 1mm, and the surface of the outer plate is subjected to powder spraying treatment;
the heat insulation material consists of flame-retardant fireproof PU and heat insulation glass wool, and the thickness is 100mm.
Further, the box body is provided with a double-layer silicon rubber sealing strip for sealing the box door;
the door is provided with a door lock.
Further, a plurality of movable casters are mounted at the bottoms of the test box and the cabinet.
The beneficial effects are that:
the animal experiment box comprises a test box, a cabinet and a transparent box; forming a sealed experimental space in the test box; the camera, the lighting device, the temperature sensor, the humidity sensor, the noise detector, the loudspeaker, the carbon dioxide detector, the oxygen detector, the air outlet, the air return and the water outlet are arranged in the box body, and the gas environment, the temperature, the humidity, the noise frequency and the intensity, the illumination intensity and the time in the experimental space of the test box can be finely adjusted through the cabinet, so that the simulation of the gas environment, the temperature, the humidity, the noise and the illumination is realized; a plurality of transparent boxes can be placed in the box body, a water tank and a food tank are placed in the transparent boxes, and a hanging device is arranged in the transparent boxes, so that the rodents can be hung in a tail mode through the hanging device to simulate a microgravity environment; meanwhile, the animal model and the environment in the experimental space can be monitored in real time by arranging the camera; therefore, the programmable animal experiment box has the characteristics of multiple controllable environmental factors, high control precision and capability of being observed in real time.
Drawings
FIG. 1 is a schematic perspective view of a programmable animal experiment box for simulating a natural environment;
FIG. 2 is a perspective view of a test case;
FIG. 3 is a front view of the test chamber of FIG. 1;
FIG. 4 is a cross-sectional view taken along section A-A of FIG. 3;
fig. 5 is a view in the direction B-B of fig. 3.
The device comprises a 1-test box, a 2-cabinet, a 3-transparent box, a 4-camera, a 5-lighting device, a 6-loudspeaker, a 7-carbon dioxide detection hole, an 8-oxygen detection hole, a 9-sensor mounting hole, a 10-test hole, an 11-air return port, a 12-noise detector, a 13-threading hole, a 14-evaporator, a 15-circulating fan and a 16-air outlet.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
As shown in the structures of fig. 1 and 2, the present embodiment provides a programmable animal experiment box for simulating a specific environment, which is used for rodents and experimental monkeys, and comprises a test box 1, a cabinet 2 and a transparent box 3; the test box 1 is used for providing a space for animal experiments; the cabinet 2 is used for controlling the test box 1 to simulate a special environment;
the test box 1 comprises a box body and a box door rotatably arranged at one side of the box body, and a sealed experiment space is formed in the box body by closing the box door; when the box door is closed, the box door is sealed with the box body; the box body is provided with a double-layer silicon rubber sealing strip for sealing the box door; the door is provided with a door lock; as shown in fig. 2, a camera 4, a lighting device 5, a temperature sensor, a humidity sensor, a noise detector 12, a loudspeaker 6, a carbon dioxide detector and an oxygen detector are fixedly arranged on the inner top wall of the box body; the camera 4 can monitor the space in the box body in real time, can record the view in the box body into video for storage, or can directly display the video on display equipment outside the box body in real time, and the camera 4 can have an infrared function; the lighting device 5 may be a tube, a bulb, such as: yellow lamp tubes can be placed in the lamp tube, the illumination intensity is 15-20 lx, and a lamp timing switch and a cycle can be set; the box body is provided with a carbon dioxide detection hole 7, an oxygen detection hole 8 and a sensor mounting hole 9; the carbon dioxide detector is arranged in the carbon dioxide detection hole 7 and is used for detecting the concentration of carbon dioxide in the box body; the oxygen detector is arranged in the oxygen detection hole 8 and is used for detecting the oxygen concentration in the box body; the noise detector 12 can be directly arranged at the top of the box body and is used for detecting the noise intensity in the box body; the temperature sensor is used for detecting the temperature in the box body; the humidity sensor is used for detecting the humidity in the box body; a temperature sensor and a humidity sensor are installed in the sensor installation hole 9; an air outlet is arranged on the top wall of the box body and is used for inputting gas into the box body or a gas circulation outlet in the box body; an air return port 11 is arranged on the rear side wall of the box body and is used for a gas circulation inlet in the box body; a test hole 10 is arranged on the side wall of the box body, and the test hole 10 is used for externally connecting a test power line and a signal line; a water outlet is arranged on the bottom wall of the box body and is used for discharging accumulated water in the box body; the top of the box body can be also provided with an exhaust port 16, and when the gas environment is controlled, the gas in the box body can be exhausted through the exhaust port firstly, so that the difficulty in adjusting the gas concentration is reduced;
the transparent box 3 is arranged in the box body and is provided with a vent hole communicated with the experimental space and a small door which is opened outwards; the ventilation holes can ensure the gas circulation, so that the gas concentration and the temperature and the humidity in each transparent box 3 are consistent and consistent with the large environment in the box body; the rodents or experimental monkeys are conveniently put in or taken out through the small doors; a water tank and a food tank are arranged in the transparent box 3; as shown in fig. 2, 4 transparent boxes 3 are placed side by side in the box body, so that the environment simulation function of 4 animals can be performed simultaneously; a hanging device for hanging tails is arranged at the top of the transparent box 3; the suspension device is a cross rod or a tail suspension chain; the transparent box 3 can be made of acrylic material and has a cubic structure with the side length of 200-600 mm; the height and width of the small door are 100-400 mm; the bottom of the transparent box 3 is provided with a fecal collecting device; the aperture of the vent hole is 10mm; tail hanging is carried out on the rodents through a hanging device, and the microgravity effect is simulated;
the cabinet 2 is provided with a controller, a control panel, a display screen and a status indicator lamp; the controller is in signal connection with the camera 4, the lighting device 5, the temperature sensor, the humidity sensor, the noise detector 12, the loudspeaker 6, the carbon dioxide detector, the oxygen detector, the control panel, the display screen and the status indicator lamp; the control panel and the display screen are used for inputting control instructions; the display screen is used for displaying control information; the status indicator lamp is used for indicating the running status of the test box 1; the controller is used for controlling the switch of the camera 4 and the lighting device 5 according to the control instruction and controlling the temperature, humidity, brightness, noise intensity, carbon dioxide concentration and oxygen concentration in the box body. The control panel is provided with a buzzer for emitting prompt tones, a power button for controlling a power switch, a speed regulation button for regulating noise frequency, a reset button for recovering an original state, an emergency stop button for emergency stop and an overtemperature protector for setting the upper limit of the temperature in the experimental space. The status indicator light may include a fault indicator light, an operation indicator light, a power indicator light, a dehumidification indicator light, and a humidification indicator light; the fault indicator lamp is red, when the lamp is on, the fault is generated, at the moment, the machine stops running, beeps, and waits for the fault state to be relieved; the running indicator light is green, and when the light is on, the running indicator light indicates that the machine is running; the power indicator light is yellow, and when the light is on, the power of the control panel is turned on; the dehumidifying indicator light is blue, and when the lamp is on, the dehumidifying indicator light indicates that the machine is running for dehumidifying; the humidification indicator light is purple, and when the lamp is on, the humidification indicator light indicates that the machine is running a humidification function.
The animal experiment box also comprises a heating device, a refrigerating device, a humidifying device, a gas cylinder and an adjustable air deflector; the air conditioner can also comprise a circulating fan 15 arranged in the box body, so that the concentration and the temperature and the humidity of air in the box body are uniform as soon as possible; the heating device is arranged in the test box 1 and is used for increasing the temperature in the box body; the heating device can be a long-life nichrome heating wire heater; the refrigerating device comprises an evaporator 14 arranged in the test box 1 and a condenser arranged in the cabinet 2 and is used for reducing the temperature in the box body; the humidifying device is arranged in the test box 1 and is used for improving the humidity in the box body; the humidifying device can adopt steam humidification or ultrasonic humidification; the gas cylinders are arranged at the outer sides of the test box 1 and the cabinet 2, a plurality of gas cylinders can be arranged and used for respectively storing carbon dioxide, oxygen and nitrogen, the gas cylinders are communicated with the test box 1 through pipelines and used for introducing the carbon dioxide, the oxygen and the nitrogen into the box body of the test box 1, the concentration of the carbon dioxide and the concentration of the oxygen can be regulated by controlling the proportion of the carbon dioxide, the oxygen and the nitrogen which are input, and the premixed gas of the carbon dioxide, the oxygen and the nitrogen with preset concentration and proportion can also be directly introduced; an electromagnetic valve in signal connection with the controller is arranged in the pipeline, and the concentration of carbon dioxide and the concentration of oxygen in the box body are regulated by controlling the electromagnetic valve; the adjustable air deflector is installed in the box body and used for improving the uniformity of temperature and humidity distribution, as shown in fig. 2 and 3, the adjustable air deflector is installed at the top of the box body and is positioned at the upper side of the circulating fan 15.
In order to achieve noise control, the cabinet 2 is provided with a noise generator and an audio power amplifier; the noise generator can adopt a J2224 audio generator, and the frequency range can be regulated through the control panel; the noise generator is in signal connection with the loudspeaker 6 through an audio power amplifier; the noise generator adopts a transistor vibration circuit for generating a sine wave signal, and directly drives the loudspeaker 6 to sound after being amplified by an audio power amplifier.
In a specific embodiment, the experimental space of the test box 1 can be a cuboid cavity, and the length, width and height dimensions are 1000mm multiplied by 800mm multiplied by 1000mm; the external length, width and height dimensions of the test box 1 may be: 1200mm x 1400mm x 1300mm; the external length, width and height dimensions of the cabinet 2 may be: 900mm by 1200mm by 1400mm. The wall and the door of the box body comprise an inner plate, an outer plate and a heat insulation material clamped between the inner plate and the outer plate; the inner plate is a 304 stainless steel plate with the thickness of 1 mm; the outer plate is a double-sided galvanized steel plate with the thickness of 1mm, and the surface is subjected to powder spraying treatment; the heat insulating material consists of flame-retardant fireproof PU and heat insulating glass wool, and has a thickness of 100mm. In addition, a plurality of movable casters are arranged at the bottoms of the test box 1 and the cabinet 2, and the positions of the movable casters are conveniently adjusted through the movable casters.
Through the programmable animal experiment box simulating the special environment, the temperature adjustment of +/-0.2 ℃ in the temperature range of 0-100 ℃ and the adjustment of +/-2% in the humidity range of 10-98% can be realized, and the illumination is 15-20 lx; the camera 4 in the box body can realize video monitoring, can observe the dynamics of rodents or experimental monkeys at any time, the resolution ratio of the camera 4 is more than 720p, the area of 80 multiplied by 80cm is covered, the output interface is a USB or a network port, the cable is output to the outside of the box body, and the video can be recorded at a computer end and has a review function; the noise of 35-65 dB can be generated in the test box 1, the noise can be manually adjusted, and the noise can be collected and displayed in real time; premixed gas (oxygen, carbon dioxide and nitrogen) is input from an air outlet of the box body, and the oxygen and carbon dioxide gas concentrations in the test box are collected and displayed in real time.
The animal experiment box comprises a test box 1, a cabinet 2 and a transparent box 3; forming a sealed experimental space in the test box 1; the camera 4, the lighting device 5, the temperature sensor, the humidity sensor, the noise detector 12, the loudspeaker 6, the carbon dioxide detector, the oxygen detector, the air outlet, the air return 11 and the water outlet are arranged in the box body, and the gas environment, the temperature, the humidity, the noise frequency, the intensity, the illumination intensity and the time in the experimental space of the test box 1 can be finely regulated through the cabinet 2, so that the simulation of the gas environment, the temperature, the humidity, the noise and the illumination is realized; a plurality of transparent boxes 3 can be placed in the box body, a water tank and a food tank are placed in the transparent boxes 3, and a hanging device is arranged in the transparent boxes 3, so that tail hanging can be carried out on rodents through the hanging device, the microgravity effect is simulated, and microgravity environment simulation is carried out; meanwhile, the animal model and the environment in the experimental space can be monitored in real time by arranging the camera 4; therefore, the programmable animal experiment box has the characteristics of multiple controllable environmental factors, high control precision and capability of being observed in real time.
It will be apparent to those skilled in the art that various modifications and variations can be made to the embodiments of the present invention without departing from the spirit and scope of the invention. Thus, it is intended that the present invention also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.
Claims (10)
1. A programmable animal experiment box for simulating a special environment, which is characterized by being used for rodents and experimental monkeys and comprising a test box, a cabinet and a transparent box;
the test box comprises a box body and a box door rotatably arranged at one side of the box body, and a sealed experiment space is formed in the box body by closing the box door; a camera, a lighting device, a temperature sensor, a humidity sensor, a noise detector, a loudspeaker, a carbon dioxide detector and an oxygen detector are fixedly arranged on the top wall of the inner side of the box body; the carbon dioxide detector is used for detecting the concentration of carbon dioxide in the box body; the oxygen detector is used for detecting the oxygen concentration in the box body; the noise detector is used for detecting the noise intensity in the box body; the temperature sensor is used for detecting the temperature in the box body; the humidity sensor is used for detecting the humidity in the box body; an air outlet is formed in the top wall of the box body, an air return opening is formed in the rear side wall of the box body, a test hole is formed in the side wall of the box body, and a water outlet is formed in the bottom wall of the box body;
the transparent box is placed in the box body and is provided with a vent hole communicated with the experimental space and a small door which is opened outwards; a water tank and a food tank are arranged in the transparent box;
the cabinet is provided with a controller, a control panel, a display screen and a status indicator lamp; the controller is in signal connection with the camera, the lighting device, the temperature sensor, the humidity sensor, the noise detector, the loudspeaker, the carbon dioxide detector, the oxygen detector, the control panel, the display screen and the status indicator lamp; the control panel and the display screen are used for inputting control instructions; the display screen is used for displaying control information; the state indicator lamp is used for indicating the running state of the test box; the controller is used for controlling the switch of the camera and the lighting device according to the control instruction and controlling the temperature, the humidity, the brightness, the noise intensity, the carbon dioxide concentration and the oxygen concentration in the box body.
2. The programmable animal experiment box of claim 1, further comprising a heating device, a cooling device, a humidifying device, a gas cylinder, and an adjustable air deflector;
the heating device is arranged in the test box and used for increasing the temperature in the box;
the refrigerating device comprises an evaporator arranged in the test box and a condenser arranged in the cabinet and is used for reducing the temperature in the box;
the humidifying device is arranged in the test box and used for improving the humidity in the box body;
the gas cylinder is communicated with the test box through a pipeline and is used for introducing carbon dioxide, oxygen and nitrogen into the box body of the test box;
an electromagnetic valve in signal connection with the controller is arranged in the pipeline, and the concentration of carbon dioxide and the concentration of oxygen in the box body are adjusted by controlling the electromagnetic valve;
the adjustable air deflector is arranged in the box body and used for improving the uniformity of temperature and humidity distribution.
3. The programmable animal experiment box of claim 2, wherein the cabinet is provided with a noise generator and an audio power amplifier;
the noise generator is in signal connection with the loudspeaker through the audio power amplifier; the noise generator adopts a transistor vibration circuit for generating sine wave signals, and directly drives the loudspeaker to sound after being amplified by the audio power amplifier.
4. The programmable animal experiment box according to claim 1, wherein the control panel is provided with a buzzer for emitting a warning tone, a power button for controlling a power switch, a speed adjusting button for adjusting a noise frequency, a reset button for restoring an original state, an emergency stop button for emergency stop, and an overtemperature protector for setting an upper temperature limit in the experiment space.
5. The programmable animal experiment box of claim 1, wherein a hanging device for hanging the tail is installed at the top of the transparent box.
6. The programmable animal experiment box of claim 5, wherein the suspension device is a cross bar or a tail suspension chain for tail suspension of rodents to simulate the microgravity effect.
7. The programmable animal experiment box according to claim 5, wherein the experiment space of the test box is a cuboid cavity with the dimensions of 1000mm x 800mm x 1000mm;
the transparent box is made of acrylic materials and is of a cube-shaped structure with the side length of 200-600 mm;
the height and the width of the small door are 100-400 mm;
the bottom of the transparent box is provided with a fecal collecting device;
the aperture of the vent hole is 10mm.
8. The programmable animal experiment box according to any one of claims 1 to 7, wherein the box wall and the box door each comprise an inner plate, an outer plate, and a heat insulating material interposed between the inner plate and the outer plate;
the inner plate is a 304 stainless steel plate with the thickness of 1 mm;
the outer plate is a double-sided galvanized steel plate with the thickness of 1mm, and the surface of the outer plate is subjected to powder spraying treatment;
the heat insulation material consists of flame-retardant fireproof PU and heat insulation glass wool, and the thickness is 100mm.
9. The programmable animal experiment box according to any one of claims 1 to 7, wherein the box body is provided with a double-layered silicone rubber sealing strip for sealing the box door;
the door is provided with a door lock.
10. The programmable animal experiment box of any one of claims 1-7, wherein a plurality of casters are mounted to the bottom of the test box and the cabinet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410057028.2A CN117694257A (en) | 2024-01-15 | 2024-01-15 | Programmable animal experiment box for simulating special environment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410057028.2A CN117694257A (en) | 2024-01-15 | 2024-01-15 | Programmable animal experiment box for simulating special environment |
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| CN117694257A true CN117694257A (en) | 2024-03-15 |
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| CN202410057028.2A Pending CN117694257A (en) | 2024-01-15 | 2024-01-15 | Programmable animal experiment box for simulating special environment |
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| CN (1) | CN117694257A (en) |
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