CN117653564A - Anti-aging anhydrous essential oil and preparation method thereof - Google Patents
Anti-aging anhydrous essential oil and preparation method thereof Download PDFInfo
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- CN117653564A CN117653564A CN202211062764.4A CN202211062764A CN117653564A CN 117653564 A CN117653564 A CN 117653564A CN 202211062764 A CN202211062764 A CN 202211062764A CN 117653564 A CN117653564 A CN 117653564A
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- essential oil
- parts
- oil
- aging
- anhydrous
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Abstract
The invention belongs to the technical field of skin care products, and particularly relates to an anti-aging anhydrous essential oil and a preparation method thereof. The invention provides an anti-aging anhydrous essential oil, which comprises the following components: 0.5 to 3 parts of compound plant essential oil, 0.5 to 8 parts of compound solid fat-soluble active matter, 0.01 to 2 parts of teprenone, 1 to 5 parts of flaxseed and celery extract, 25.5 to 92 parts of compound plant oil, 5 to 12 parts of olive squalane, 0.1 to 1.2 parts of natural tocopherol, 5 to 9.5 parts of triglyceride (ethyl caproic acid) ester and 0.01 to 0.05 part of dimethyl methoxy phenylpropanol. The invention adopts the synergistic compatibility of the component esters, has the effects of resisting oxidation, resisting saccharification and resisting photoaging, and accurately solves the problems of large pores, rough skin texture, unsmooth skin blood circulation, tarnish, yellow and matt skin and the like which plague the public.
Description
Technical Field
The invention belongs to the technical field of skin care products, and particularly relates to an anti-aging anhydrous essential oil and a preparation method thereof.
Background
With the change of human life style and the acceleration of social rhythm, people are generally in a higher life pressure state, endless stay up, fluctuation and fluctuation emotion, increasingly serious environmental pollution, high-energy electronic radiation, abuse of over-processed foods and chemical drugs, and increasingly hot weather and sun exposure, excessive oxygen free radicals can be generated inside and outside a human body, and can damage biological macromolecules, so that in vivo enzyme inactivation, protein denaturation and attack of cell membranes and mitochondrial membranes are caused, unsaturated fatty acids in membrane lipid are oxidized, and free radical chain attack reactions are caused, cell structures are damaged, and cell aging is accelerated, and the action mechanism of free radical aging is the action mechanism of free radical aging; the nature of saccharification reaction is an oxidation phenomenon, namely, in the process of metabolism in vivo, the amino group of protein and reduced glucose are oxidized to generate bonding polymerization reaction, so that initial saccharification is formed; as these polymers continue to accumulate to an inability to metabolize and degrade, irreversible advanced glycosylation end products (AGES) continue to form and cause the protein tissue to lose normal function; at the same time, photoaging is essentially the same free radical damage because excessive solar radiation penetrates the epidermis and dermis layers and generates free radicals, leading to lipid oxidation and release of Matrix Metalloproteinases (MMPS), destroying elastin and collagen fibers, and continuing accumulation, ultimately leading to rough skin, deepening wrinkles, coarse pores, irregular pigmentation, poor epidermal keratinization, and accelerated skin aging.
Therefore, the skin care product is required to truly realize the anti-aging effect, and must realize the effects of oxidation resistance, saccharification resistance and photoaging resistance at the same time. The skin care product has the effects of resisting oxidation, saccharification and photoaging, is high in stability, is not easy to inactivate, and can be really absorbed through skin.
For example: skin care products on the market, some of which use various vitamins to achieve antioxidant effect, such as ascorbic acid, tocopherol or tocotrienol, retinol and its various derivatives, carotenoids including oxygen-containing derivatives lutein, lycopene, lutein, zeaxanthin, etc.; some of the antioxidants can be selected from the antioxidants of human bodies, such as SOD, glutathione, lipoic acid and coenzyme Q10; some will choose to use various flavonoids such as anthocyanins, procyanidins, various plant polyphenols; some will select small molecule antioxidant and anti-glycation peptides such as carnosine, decarboxylated carnosine. However, the above-mentioned common antioxidants and anti-glycation actives all have their own drawbacks: ascorbic acid is water-soluble, has poor transdermal absorption and is extremely easy to oxidize and change color; carotenoids are very sensitive to oxygen, light, heat and acids because of having long-chain conjugated double bonds, are very susceptible to degradation and inactivation, and need to avoid co-compatibility with metal ions; SOD has super molecular weight, can not realize transdermal absorption at all, can be deactivated rapidly in a very short time, and glutathione is an active substance which is very easy to deactivate, is water-soluble, but is nearly half deactivated after one week once being dissolved in water when being used in skin care products, and is completely deactivated after one month, and the molecular weight of coenzyme Q10 is more than 863, so that the transdermal absorption is difficult to realize; the weight-reducing idebenone of Q10 has a molecular weight of 338.4, but has slight irritation to skin when used at high concentration, and only 0.5% of idebenone ointment is subjected to a patch test, so that the possibility of contact dermatitis is shown, the stability at normal temperature and normal pressure is far worse than that of Q10, strong light needs to be avoided, the idebenone is refrigerated and stored, and the idebenone has high requirements on PH environment, and the most suitable PH value is 5, meta acid or meta alkali can accelerate decomposition and inactivation; alpha lipoic acid has no irritation and cytotoxicity to skin, but is easy to degrade and inactivate by illumination or heating, and oil-water is difficult to dissolve, and the alpha lipoic acid has slightly acidic requirement to PH environment and is only suitable for compatibility within the range of 2.7 to 4.7; resveratrol is also insoluble in oil and water, cannot be stored at normal temperature to have active value, and needs to be stabilized by inclusion technology; the color stability of flavonoids and anthocyanidins is poor, oxidative discoloration is very easy, and the flavonoid raw materials are insoluble or slightly soluble in water and are not easy to dissolve in alcohol and grease; the plant polyphenol such as caffeic acid, ferulic acid, gallic acid and ellagic acid has larger conjugated systems, has poor stability, is easy to degrade, needs to be protected from light and heat, is very sensitive to heavy metal ions, is easy to change color, and needs to be matched with a chelating agent; carnosine, although being thermally stable, has a small molecular weight and is sufficiently safe, is difficult to cross the keratinous barrier to reach the dermis layer for its effectiveness because of its positive charge and water solubility, and has strict requirements for the PH range of the formulation, is not compatible with divalent metal ions, and needs to be limited to an extremely narrow range of 5.5 to 7.5, and requires a large amount of penetration aid to aid its penetration, while an excess of penetration aid is difficult to withstand for sensitive skin.
Disclosure of Invention
The invention aims to provide the anti-aging anhydrous essential oil and the preparation method thereof, and the anti-aging anhydrous essential oil provided by the invention is comprehensively aimed at different types of free radicals, can absorb ultraviolet rays of a special wave band, has the effects of resisting oxidization, resisting saccharification and resisting photoaging, ensures that skin is compact, fine and elastic, has white, clear and transparent complexion, presents healthy red and halation, is an anhydrous formula of a full-oil phase, is rich in omeg3 and omega6, and contains terpene essential oil, so that the skin care effect is far superior to that of common essences.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides an anti-aging anhydrous essential oil which comprises the following components in parts by weight:
0.5 to 3 parts of compound plant essential oil, 0.5 to 8 parts of compound solid fat-soluble active matter, 0.01 to 2 parts of teprenone, 1 to 5 parts of flaxseed and celery extract, 25.5 to 92 parts of compound plant oil, 5 to 12 parts of olive squalane, 0.1 to 1.2 parts of natural tocopherol, 5 to 9.5 parts of triglyceride (ethyl caproic acid) ester and 0.01 to 0.05 part of dimethyl methoxy phenylpropanol;
the compound plant essential oil comprises osmanthus essential oil, permanent flower essential oil, frankincense essential oil and myrrh essential oil;
The compound solid fat-soluble active substances comprise stearyl glycyrrhetinate, oryzanol, shea butter non-saponified substances, acetyl gingerol and esterified plant polyphenol; the esterified plant polyphenol comprises palmitoyl tea extract and/or coastal pine extract;
the compound vegetable oil comprises jojoba seed oil, perilla seed oil, cucumber seed oil, watermelon seed oil, peony seed oil and oat seed oil.
Preferably, the compound plant essential oil comprises the following components in parts by weight:
0.2 to 1.2 portions of osmanthus essential oil, 0.1 to 0.8 portion of permanent flower essential oil, 0.1 to 0.2 portion of milk essential oil and 0.1 to 0.3 portion of myrrh essential oil.
Preferably, the compound plant essential oil further comprises magnolia alba essential oil.
Preferably, the compound plant essential oil also comprises 0.01-0.25 part of magnolia alba essential oil by mass part.
Preferably, the compound vegetable oil comprises the following components in parts by weight:
10-30 parts of jojoba seed oil, 10-35 parts of perilla seed oil, 1-5 parts of cucumber seed oil, 1.5-8 parts of watermelon seed oil, 2-9 parts of peony seed oil and 1-5 parts of oat seed oil.
Preferably, the compound solid fat-soluble active substance comprises the following components in parts by mass:
0.05 to 0.5 part of stearyl alcohol glycyrrhetinate, 0.05 to 0.5 part of oryzanol, 0.1 to 3 parts of shea butter non-saponified matters, 0.1 to 2 parts of acetyl gingerol and 0.2 to 2 parts of esterified plant polyphenol.
Preferably, the esterified plant polyphenol comprises palmitoyl tea extract and coastal pine extract, and the mass ratio of the palmitoyl tea extract to the coastal pine extract is (0.5-1) to (0.5-1).
The invention provides a preparation method of the anti-aging anhydrous essential oil, which comprises the following steps:
under a first temperature condition, first mixing dimethyl methoxy phenylpropanoid dihydropyran alcohol, stearyl glycyrrhetinate, oryzanol and triglyceride (ethylhexanoic acid) ester to obtain a first mixture;
cooling to a second temperature, and mixing the first mixture, the non-saponified shea butter, the acetyl gingerol and the esterified plant polyphenol for the second time to obtain a second mixture;
cooling to a third temperature, and third mixing the second mixture, jojoba seed oil, flaxseed, celery extract and teprenone to obtain a third mixture;
cooling to room temperature, and fourth mixing the third mixture, the compound plant essential oil, the perilla seed oil, the cucumber seed oil, the watermelon seed oil, the peony seed oil, the oat seed oil, the olive squalane and the natural tocopherol to obtain the anti-aging anhydrous essential oil.
Preferably, the first temperature is 80-90 ℃; the second temperature is 65-75 ℃; the third temperature is 40-50 ℃.
Preferably, the heat preservation time of the first mixing is 10-15 min; the heat preservation time of the second mixing is 10-15 min; the heat preservation time of the third mixing is 5-10 min; the fourth mixing heat preservation time is 60-80 min.
The invention provides an anti-aging anhydrous essential oil which comprises the following components in parts by weight: 0.5 to 3 parts of compound plant essential oil, 0.5 to 8 parts of compound solid fat-soluble active matter, 0.01 to 2 parts of teprenone, 1 to 5 parts of flaxseed and celery extract, 25.5 to 92 parts of compound plant oil, 5 to 12 parts of olive squalane, 0.1 to 1.2 parts of natural tocopherol, 5 to 9.5 parts of triglyceride (ethyl caproic acid) ester and 0.01 to 0.05 part of dimethyl methoxy phenylpropanol; the compound plant essential oil comprises osmanthus essential oil, permanent flower essential oil, frankincense essential oil and myrrh essential oil; the compound solid fat-soluble active substances comprise stearyl glycyrrhetinate, oryzanol, shea butter non-saponified substances, acetyl gingerol and esterified plant polyphenol; the esterified plant polyphenol comprises palmitoyl tea extract and/or coastal pine extract; the compound vegetable oil comprises jojoba seed oil, perilla seed oil, cucumber seed oil, watermelon seed oil, peony seed oil and oat seed oil. The anti-aging anhydrous essential oil provided by the invention is compounded by adopting the osmanthus fragrans essential oil, the permanent flower essential oil, the frankincense essential oil and the myrrh essential oil, wherein beta-diketone contained in the permanent flower essential oil can synergistically enhance the efficacy of promoting skin regeneration by ionone in the osmanthus fragrans essential oil, the myrrh essential oil is matched to help inhibit collagenase, and then the frankincense essential oil is cooperatively compounded, the frankincense essential oil also contains trace ketone aromatic molecules with huge efficacy, so that the content of type one collagen in skin can be improved, meanwhile, the milk essential oil also contains sesquiterpene with proper proportion, so that the skin immunity can be balanced, the tolerance of the skin can be improved, and the anti-aging anhydrous essential oil is very mild and safe, has excellent repairing and regenerating effects with the myrrh essential oil, and realizes the anti-aging effect; meanwhile, the compound solid fat-soluble active substance component adopted by the invention comprises palmitoyl tea extract and/or coastal pine extract, which are two esterified plant polyphenols, and the common plant polyphenols have no oil solubility, so that the compound solid fat-soluble active substance component cannot be smoothly applied to essence of a pure oil phase, but the two plant polyphenols are grafted with palmitoyl groups, so that the compound solid fat-soluble active substance component has excellent lipophilicity and high transdermal absorption rate, and can be smoothly applied to essence of a full oil phase. The palmitoyl tea extract is rich in catechin, has super oxidation resistance, can inhibit damage of free radicals to cells, can act on a dermal papilla layer, effectively resists skin aging, protects skin from oxidative stress, protects skin proteins and lipids from being damaged by the free radicals, and improves the microcirculation system of the skin and inhibits saccharification by strengthening capillary walls; the coastal pine extract is rich in various active polyphenols, acts on the dermal papilla layer, and is effective in resisting skin aging, protecting skin from oxidative stress, and protecting skin proteins and lipids from free radical damage. In addition, the components of the flaxseed and celery extract adopted by the invention contain cyclopeptide and senkyunolide, so that the activity of mitochondria can be protected, the metabolism of cells can be promoted, the collagen sheath structure around pores can be enhanced, the formation of layered proteins releasing MMP-1 can be inhibited, collagen and elastin can be promoted, the effect of preventing the aging of a supporting structure can be achieved, smaller and more compact pore structures can be maintained, the density of dermis layers can be improved, the compactness and elasticity of skin can be improved, the isotropy of the skin can be improved, better diffuse reflection of incident light rays can be helped, better light reflection effect can be possessed by the skin, the natural silk-like appearance of the skin can be endowed, the effect of compactness and fineness can be further improved, finally, the compound vegetable oil adopted by the invention comprises jojoba seed oil, perilla seed oil, cucumber seed oil, watermelon seed oil, peony seed oil and oat seed oil, the high proportion of the common perilla seed oil can promote the metabolism of the skin, improve the skin moisture content, relieve the skin dryness, the skin permeability can be more improved, the penetration rate of other active substances to the skin can be promoted, the absorption of the active substances can be promoted, and the tetraenoic acid can be inhibited, and the chronic inflammation of the skin can be relieved; the cucumber seed oil has high unsaturated fatty acid content, is rich in microelements such as Mg, ca, fe, cu and the like, is rich in protein mercapto (P-SH), thiamine, riboflavin, squalene and tocopherol, and has excellent antioxidation value; the watermelon seed oil has excellent scavenging ability to hydroxyl free radical and DDPH free radical, and can obviously inhibit lipid peroxidation; the peony seed oil is rich in omiga3, omiga6, DHA, paeonol, peony saponin, peony polysaccharide, fucosterol, squalene, gamma tocopherol and phytosterol (sitosterol, delta 5-avenanthol, cholesterol), and has excellent effects of resisting oxidation, diminishing inflammation, resisting bacteria, delaying aging and the like; oat seed oil contains rich oat anthracene amide, VE and sterol substances, has good antiallergic, anti-irritant and antioxidant effects, can effectively remove and prevent the phenomenon of redness on the surface of skin, and has good protective effect on allergic skin. Therefore, the anti-aging anhydrous essential oil provided by the invention adopts the synergistic compatibility of compound plant essential oil, a plurality of compound solid fat-soluble active substances, teprenone, and linseed rich in cyclopeptide and senkyunolide with celery extract, compound plant oil, olive squalane, natural tocopherol and triglyceride (ethyl caproic acid) ester, comprehensively aims at different types of free radicals, can absorb ultraviolet rays of a special wave band, has the effects of resisting oxidation, resisting saccharification and resisting photoaging, and accurately solves the problems of coarse pores, rough skin texture, unsmooth skin blood circulation, darkish yellow and matt skin and the like which are puzzled to the public. The skin is compact, fine, smooth and elastic, and the skin color is white, clear and transparent, and the skin is healthy and has reddish and bright luster.
The anti-aging anhydrous essential oil provided by the invention is also unique in the aspect of smell: the supercritical extraction osmanthus essential oil has the characteristics of unique sweetness and fragrance of fresh osmanthus flowers, lasting and strong fragrance, and the italian permanent flower essential oil has unique smell like a thick and heavy dry herb, can effectively neutralize the sweet and greasy taste of the supercritical osmanthus essential oil, and enables the essence to have more hierarchical, full and soft taste; the lemon with the raised frankincense harmonizes the unique smell of the pine plants, so that the tastes of the osmanthus fragrans and the permanent flowers can be kept thick and heavy, the whole taste can be fresh, round and fused, calm, sweet and beautiful, elegant and pleasant, and the user can be helped to restore the calm and harmony.
In conclusion, the anti-aging anhydrous essential oil emulsion essential oil provided by the invention does not contain any mineral oil, silicone oil, artificial synthetic ester, artificial essence and preservative, and has the characteristics of small molecular weight, high transdermal absorption efficiency, good stability, safety, mildness, high skin affinity, elegant and fragrant taste, easiness in acceptance by masses of audiences and the like.
Further, the compound plant essential oil also comprises white magnolia essential oil. In the invention, the neryl acetate and the neryl alcohol in the permanent flower essential oil can synergistically enhance the anti-inflammatory and antioxidant effects of the white magnolia essential oil and the osmanthus essential oil; meanwhile, the white magnolia essential oil is rich in linalool, beta ionone and phenethyl alcohol, contains esters in a proper proportion, can play a synergistic anti-aging effect with the osmanthus essential oil, and has an improved efficacy; the white magnolia essential oil and the osmanthus essential oil are compounded in a synergistic way, so that the sweet and delicious taste of the essential oil provided by the invention is not delicate and is not floating, and the smell aspect can be greatly improved.
Drawings
FIG. 1 is a graph showing the anti-wrinkle effect on the right face of subject 1 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 2 is a graph showing the anti-wrinkle effect of the left face of subject 1 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 3 shows the effect of right-face texture change after 1 week of the anti-aging anhydrous essential oil prepared in comparative example 1 for trial of subject 2;
FIG. 4 shows the effect of left face texture change after 1 week of the anti-aging anhydrous essential oil prepared in comparative example 1 for trial of subject 2;
FIG. 5 is a graph showing the anti-wrinkle effect on the right face of subject 2 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 6 is a graph showing the anti-wrinkle effect of the left face of subject 2 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 7 shows the effect of shrinking pores in the right face of subject 3 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 8 shows the effect of shrinking pores in the left face of subject 3 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 9 shows the effect of pore change in the right face of subject 3 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 10 shows the effect of pore change in the left face of subject 3 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 11 is a graph showing the anti-wrinkle effect on the right face of subject 4 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 12 is a graph showing the anti-wrinkle effect of the left face of subject 4 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 13 is a graph showing the anti-wrinkle effect on the right face of subject 4 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 14 shows the anti-wrinkle effect of the anti-aging anhydrous essential oil prepared in example 1 of subject 4 after 2 weeks;
fig. 15 shows the effect of pore change in the right face of subject 5 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 16 is a graph showing the effect of pore change in the left face of subject 5 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 17 shows the effect of right-face texture change after 1 week in subject 5 on the prepared anti-aging anhydrous essential oil of example 1;
fig. 18 shows the effect of left face texture change after 1 week in subject 5 with the anti-aging anhydrous essential oil prepared in example 1;
FIG. 19 is a graph showing the anti-wrinkle effect on the right face of subject 5 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 20 is a graph showing the anti-wrinkle effect of the left face of subject 5 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 21 is a graph showing the effect of changing the purple quality of the right face of a subject 5 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 22 shows the effect of the anti-aging anhydrous essential oil of trial example 1 on the change in the purple quality of the left face of subject 5 after 1 week;
Fig. 23 is a graph showing the effect of pore change in the right face of subject 6 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 24 is a graph showing the effect of pore change in the left face of subject 6 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 25 is a graph showing the effect of pore change in the right face of subject 6 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 26 is a graph showing the effect of pore change in the left face of subject 6 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 27 is a graph showing the effect of left face texture change after 1 week of the anti-aging anhydrous essential oil prepared in comparative example 2 for trial on subject 7;
FIG. 28 is a graph showing the anti-wrinkle effect on the right face of subject 7 after 1 week of trial of the prepared anti-aging anhydrous essential oil of comparative example 2;
FIG. 29 is a graph showing the anti-wrinkle effect of the prepared anti-aging anhydrous essential oil of comparative example 2 after 1 week in subject 7;
FIG. 30 is a graph showing the effect of changing pores of the right face of subject 7 after 1 week of trial of the prepared anti-aging anhydrous essential oil of comparative example 2;
FIG. 31 is a graph showing the effect of change in left face pores after 1 week of trial of the prepared anti-aging anhydrous essential oil of comparative example 2 in subject 7;
FIG. 32 is a graph showing the effect of changing the purple quality of the right face of subject 8 after 1 week of trial of the prepared anti-aging anhydrous essential oil of comparative example 3;
FIG. 33 is a graph showing the effect of changing the purple quality of the right face of subject 8 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of comparative example 3;
FIG. 34 is a graph showing the effect of the anti-aging anhydrous essential oil of trial example 1 on the change in the purple quality of the left face of subject 8 after 1 week;
FIG. 35 is a graph showing the effect of the anti-aging anhydrous essential oil of trial example 1 on the change in the purple quality of the left face of subject 8 after 2 weeks;
fig. 36 shows the effect of pore change in the right face of subject 9 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
fig. 37 is a graph showing the effect of pore change in the left face of subject 9 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 38 is a graph showing the effect of right-hand texture change in subject 9 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 39 is a graph showing the effect of change in left face texture of subject 9 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 40 is a graph showing the anti-wrinkle effect on the right face of subject 9 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 41 is a graph showing the anti-wrinkle effect of the left face of subject 9 after 2 weeks of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 42 is a graph showing the effect of change in pores of the right face of subject 10 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 43 is a graph showing the effect of change in left facial pores of subject 10 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 44 is a graph showing the anti-wrinkle effect on the right face of subject 11 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 45 is a graph showing the anti-wrinkle effect of the left face of subject 11 after 1 week of trial of the prepared anti-aging anhydrous essential oil of example 1;
FIG. 46 is a graph showing the effect of change in right facial pores of subject 12 after 1 week of trial of the prepared anti-aging anhydrous essential oil of comparative example 3;
fig. 47 is a graph showing the effect of change in pores of the left face of subject 12 after 1 week of trial of the prepared anti-aging anhydrous essential oil of comparative example 3.
Detailed Description
The invention provides an anti-aging anhydrous essential oil which comprises the following components in parts by weight:
0.5 to 3 parts of compound plant essential oil, 0.5 to 8 parts of compound solid fat-soluble active matter, 0.01 to 2 parts of teprenone, 1 to 5 parts of flaxseed and celery extract, 25.5 to 92 parts of compound plant oil, 5 to 12 parts of olive squalane, 0.1 to 1.2 parts of natural tocopherol, 5 to 9.5 parts of triglyceride (ethyl caproic acid) ester and 0.01 to 0.05 part of dimethyl methoxy phenylpropanol;
the compound plant essential oil comprises osmanthus essential oil, permanent flower essential oil, frankincense essential oil and myrrh essential oil;
the compound solid fat-soluble active substances comprise stearyl glycyrrhetinate, oryzanol, shea butter non-saponified substances, acetyl gingerol and esterified plant polyphenol; the esterified plant polyphenol comprises palmitoyl tea extract and/or coastal pine extract;
The compound vegetable oil comprises jojoba seed oil, perilla seed oil, cucumber seed oil, watermelon seed oil, peony seed oil and oat seed oil.
In the present invention, all preparation materials/components are commercially available products well known to those skilled in the art unless specified otherwise.
The anti-aging anhydrous essential oil provided by the invention comprises 0.5-3 parts of compound plant essential oil, preferably 1-2.5 parts by mass.
In the invention, the compound plant essential oil comprises osmanthus essential oil, permanent flower essential oil, frankincense essential oil and myrrh essential oil.
According to the invention, the osmanthus essential oil can inhibit elastase and matrix metalloproteinase simultaneously, contains high-proportion ionone, and can effectively promote cell regeneration and promote wound healing.
In the invention, the osmanthus essential oil is preferably an osmanthus essential oil obtained by supercritical extraction, and more preferably an osmanthus essential oil obtained by supercritical carbon dioxide fluid extraction.
In the invention, the osmanthus essential oil is preferably an osmanthus essential oil extracted by supercritical carbon dioxide fluid. The osmanthus essential oil obtained by supercritical fluid extraction has relatively high yield, high quality and very sweet and fragrant taste. The finished product of the skin care product prepared from the osmanthus essential oil extracted by the supercritical process has longer lasting and stronger taste; compared with the osmanthus essential oil obtained by the extraction process of a water distillation method, the osmanthus essential oil is rich in phytoflavone, has the activities and effects of scavenging free radicals, resisting aging, whitening and protecting nerves, and does not contain environmental estrogen phthalate compounds; in addition, the proportion of the core aromatic molecule ionone in the osmanthus essential oil obtained by supercritical extraction is higher than that of the osmanthus essential oil obtained by the traditional water distillation method and petroleum ether extraction; finally, the supercritical extracted osmanthus essential oil does not have the special clunky taste similar to salted vegetables after being salted, and has a fresh and fragrant feel, a higher reduction degree and a flower fragrance similar to fresh flowers of osmanthus. In addition, the supercritical extracted osmanthus essential oil can obtain complete active molecules in osmanthus, so that the curative effect is more complete and comprehensive.
In the present invention, the permanent flower essential oil is particularly preferably italian permanent flower essential oil.
In the invention, the italian permanent flower essential oil contains high proportion of italian beta-diketone and curcumene, and neryl acetate and nerol, can strongly inhibit 5-LOX, and has excellent anti-inflammatory effect; in addition, italian permanent flower essential oil can also reduce alpha-2 immunoglobulin representing acute inflammation, and can stimulate human skin to synthesize hyaluronic acid by itself, so as to help to maintain the moisture of connective tissue in dermis; at the same time elastase can be inhibited. The italian permanent flower essential oil can promote the synthesis of the in vivo adolescent DEHA, and promote the synthesis of collagen of type one, type three, type four and type seven in the dermis, so that the italian permanent flower essential oil is the essential oil which is most suitable for tightening facial skin, refining skin texture and effectively shrinking pores.
In the present invention, the italian permanent flower essential oil is preferably an italian permanent flower essential oil obtained by supercritical extraction.
In the invention, the olibanum essential oil can lead the collagen of type one to be greatly increased, can improve skin immunity and tolerance, belongs to resin essential oil, is extremely mild and safe, and has extremely excellent repairing force. The emulsifiable concentrate oil is rich in about 80% monoterpenes, with the highest alpha pinene content, and has excellent vibration extraction effect on the nervous system. In addition, the emulsifiable concentrate also contains sesquiterpenes and trace ketones in a suitable proportion. The air temperature of the emulsifiable essential oil brings the peculiar smell of alpha pinene of the pine resin and the faint and bright upward lemon tone, and can help the user to calm and harmonize with the mind.
In the present invention, the essential oil of mastic is preferably an essential oil of mastic obtained by supercritical extraction.
In the present invention, the myrrh essential oil may inhibit collagenase.
In the present invention, the myrrh essential oil is preferably an essential oil extracted by a distillation method.
In the present invention, the square plant essential oil preferably further comprises magnolia alba essential oil.
In the invention, the white magnolia essential oil contains high-proportion agalloch eaglewood alcohol, beta ionone and phenethyl alcohol, and contains esters with proper proportion, so that the white magnolia essential oil can play a wonderful synergistic resonance effect with the sweet osmanthus essential oil in terms of smell and efficacy, and the efficacy can be greatly increased.
In the invention, the white magnolia essential oil is preferably white magnolia essential oil extracted by a water distillation method.
In the invention, the compound plant essential oil preferably comprises the following components in parts by mass:
0.2 to 1.2 portions of osmanthus essential oil, 0.1 to 0.8 portion of permanent flower essential oil, 0.1 to 0.2 portion of milk essential oil and 0.1 to 0.3 portion of myrrh essential oil.
In the invention, the compound plant essential oil preferably further comprises 0.01-0.25 part of magnolia alba essential oil in parts by weight.
In the invention, the compound plant essential oil more preferably comprises the following components in parts by mass: 0.5 to 1 part of osmanthus essential oil, 0.2 to 0.6 part of permanent flower essential oil, 0.12 to 0.18 part of emulsifiable concentrate essential oil, 0.5 to 0.25 part of myrrh essential oil and 0.02 to 0.2 part of white magnolia essential oil.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 0.5-8 parts of compound solid fat-soluble active substances, preferably 1-7.5 parts, and more preferably 1.7-5.6 parts.
In the invention, the compound solid fat-soluble active substance preferably comprises the following components in parts by mass:
0.05 to 0.5 part of stearyl alcohol glycyrrhetinate, 0.05 to 0.5 part of oryzanol, 0.1 to 3 parts of shea butter non-saponified matters, 0.1 to 2 parts of acetyl gingerol and 0.2 to 2 parts of esterified plant polyphenol.
In the invention, the compound solid fat-soluble active substance more preferably comprises the following components in parts by mass: 0.1 to 0.3 part of stearyl alcohol glycyrrhetinate, 0.1 to 0.3 part of oryzanol, 0.5 to 2 parts of milk wood fruit unsaponifiable matters, 0.5 to 1.5 parts of acetyl gingerol and 0.5 to 1.5 parts of esterified plant polyphenol.
In the present invention, the esterified plant polyphenol preferably comprises palmitoyl tea extract and coastal pine extract, and the mass ratio of palmitoyl tea extract to coastal pine extract is preferably (0.5-1): (0.5-1), more preferably 1:1.
In the invention, the stearyl glycyrrhetinate is an esterified derivative of glycyrrhetinic acid, belongs to pentacyclic triterpene compounds, has a similar structure to steroid hormone, can inhibit carrier hormone from increasing metabolism inactivating enzyme, is a partial agonist antagonist of glucocorticoid receptor, and can reduce or alleviate adverse reactions of hormone, drug withdrawal reaction and drug dependence while enhancing anti-inflammatory, antiallergic and anti-stress effects of glucocorticoid. The stearyl alcohol glycyrrhetinate has wide pharmacological activity, has the clinical effects of resisting inflammation, histamine, ulcer, oxidization, virus, bacteria and tumors, can inhibit the activity of tyrosinase, prevent melanin from generating, has obvious whitening effect, has extremely low toxicity, does not irritate skin, has multiple biological activities, can reduce the level change of lactate dehydrogenase, interleukin 6 and tumor necrosis factor in serum which is covered by cyclophosphamide, and can inhibit inflammation by inhibiting signal paths such as Nf- κB.
In the present invention, the oryzanol has skin care effect: oryzanol is a combined ester substance of ferulic acid and phytosterol extracted from rice bran oil and grain oil, and comprises the following main core components: the cycloartenol ferulate can increase skin blood flow, promote skin vascular peripheral microcirculation, promote dermal and epidermal communication, and increase skin nutrition supply with low concentration oryzanol; can absorb and shield ultraviolet rays (the wave band is between 280 and 320 nm) and reduce erythema solar; can inhibit cyclooxygenase activity, and has excellent antiinflammatory and antiaging effects; in addition, oryzanol can inhibit tyrosinase activity and tissue brown pigment generation.
In the invention, the non-saponified shea butter is rich in triterpene ester, aromatic resin alcohol content (about 37%), butyl alcohol content (about 25%), lupeol content (about 22%), packol content (about 5%), acetate content (40-44%), cinnamic acid content (48-52%), fatty acid ester content (8-9%), and can enhance the epidermis barrier, increase the epidermis thickness of the skin, protect the skin against environmental pressure, increase the collagen content of the dermis layer, have excellent anti-inflammatory effect, and can repair the skin problems caused by chemical pressure, ultraviolet irradiation or urban pollution.
In the present invention, the acetylgingerol is a highly effective antioxidant, and is also a very good radical quencher and a selective chelator, having excellent anti-photoaging and anti-inflammatory effects, which can inhibit matrix metalloproteinases, inhibit gene expression associated with fibroblast senescence, inhibit the expression reaction of pro-inflammatory factor IL-17A, improve skin defenses, lighten fine wrinkles, reduce uneven pigmentation, improve skin redness, and help to maintain microbial diversity of skin.
In the present invention, the palmitoyl tea extract is obtained by esterifying plant active ingredients extracted from green tea polyphenols. The green tea polyphenol of the palmitoyl tea extract rich in catechin has super-strong oxidation resistance. Catechin is the strongest antioxidant substance in plants. The palmitoyl tea extract has a unique combined anti-aging function: can inhibit the damage of free radicals to cells, acts on the dermal papilla layer, effectively resists skin aging, protects skin from oxidative stress, and protects skin proteins and lipids from being damaged by free radicals. By strengthening capillary wall, improving skin microcirculation system, and inhibiting saccharification
In the present invention, the coastal pine extract is a plant active ingredient extracted from cedar polyphenol on the bark of atlantic cedar by esterification. When the coastal pine extract contacts skin, the enzyme contained in the skin can degrade the linkage of polyphenol and lipid to release polyphenol to participate in resisting free radical, and the coastal pine extract has the effect of improving skin feel, acts on the dermal papilla layer, effectively resists skin aging, protects the skin from the influence of oxidative stress, and protects the protein and lipid of the skin from being damaged by free radical.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 0.01-2 parts of teprenone, and preferably 0.05-1 part.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 1 to 5 parts of flaxseed and celery extract, and preferably 1.5 to 4 parts.
In the invention, the flaxseed and celery extracts are flaxseed extracts and celery extracts, which contain cyclopeptides and senkyunolide, can protect mitochondrial activity, promote cellular metabolism, strengthen collagen sheath structures around pores, inhibit formation of layered proteins releasing MMP-1, promote formation of collagen and elastin, prevent aging of a supporting structure, maintain smaller and tighter pore structures, improve dermis layer density, improve skin compactness and elasticity, promote skin isotropy, help skin to better diffuse reflection incident light, enable skin to have better light reflection effect, endow skin with natural silk-like appearance, and be more compact and fine.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 25.5-92 parts of compound plant oil, preferably 30-85 parts, and more preferably 38.5-75 parts.
In the invention, the compound vegetable oil preferably comprises the following components in parts by mass:
10-30 parts of jojoba seed oil, 10-35 parts of perilla seed oil, 1-5 parts of cucumber seed oil, 1.5-8 parts of watermelon seed oil, 2-9 parts of peony seed oil and 1-5 parts of oat seed oil.
In the invention, the compound vegetable oil more preferably comprises the following components in parts by mass: 15-25 parts of jojoba seed oil, 15-30 parts of perilla seed oil, 1.5-4 parts of cucumber seed oil, 2-6 parts of watermelon seed oil, 3-6 parts of peony seed oil and 2-4 parts of oat seed oil.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 5-12 parts of olive squalane, and preferably 6-10 parts.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 0.1-1.2 parts of natural tocopherol, and preferably 0.3-1 part.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 5-9.5 parts of triglyceride (ethyl caproic acid) ester, preferably 6-8 parts.
In the present invention, the tri (ethylhexanoic acid) ester is a triester composed of a medium-chain branched fatty acid and glycerin, and is capable of solubilizing dimethylmethoxyphenylpropandiol, and the stearyl alcohol glycyrrhetinate, oryzanol, the unsaponifiable fraction of shea butter, acetogingerol and esterified plant polyphenol in the compound solid fat-soluble active substance are excellent in warm and skin-friendly properties and stability.
Based on the mass parts of the compound plant essential oil, the anti-aging anhydrous essential oil provided by the invention comprises 0.01-0.05 part of dimethyl methoxy phenylpropanol, and preferably 0.02-0.04 part of dimethyl methoxy phenylpropanol.
In the invention, the dimethylmethoxyphenylalaninol has double scavenging ability to Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS), and has a broad protective effect against the reactive reactant of failure; in the invention, the dimethylmethoxyphenylalanyl dihydropyranol can protect various vegetable oils rich in polyunsaturated fatty acids in the essential oil formulation from oxidative deterioration. And the oryzanol, the acetyl gingerol and the non-saponified shea fruit are cooperated to play the role of resisting photoaging.
In the invention, the unit 1 of the mass parts of each component in the anti-aging anhydrous essential oil, the unit 1 of the mass parts of each component in the compound plant oil and the unit 1 of the mass parts of each component in the compound solid fat-soluble active substance are preferably the same.
The invention provides a preparation method of the anti-aging anhydrous essential oil, which comprises the following steps:
under a first temperature condition, first mixing dimethyl methoxy phenylpropanoid dihydropyran alcohol, stearyl glycyrrhetinate, oryzanol and triglyceride (ethylhexanoic acid) ester to obtain a first mixture;
cooling to a second temperature, and mixing the first mixture, the non-saponified shea butter, the acetyl gingerol and the esterified plant polyphenol for the second time to obtain a second mixture;
cooling to a third temperature, and third mixing the second mixture, jojoba seed oil, flaxseed, celery extract and teprenone to obtain a third mixture;
cooling to room temperature, and fourth mixing the third mixture, the compound plant essential oil, the perilla seed oil, the cucumber seed oil, the watermelon seed oil, the peony seed oil, the oat seed oil, the olive squalane and the natural tocopherol to obtain the anti-aging anhydrous essential oil.
The invention firstly mixes dimethyl methoxy phenylpropanoid dihydropyranol, oryzanol and triglyceride (ethylhexanoic acid) ester under a first temperature condition to obtain a first mixture.
In the present invention, the first temperature is preferably 80 to 90 ℃, more preferably 85 ℃.
In the present invention, the incubation time of the first mixing is preferably 10 to 15 minutes, more preferably 10 minutes.
In the present invention, the first mixing is preferably performed under stirring, and the rotation speed of the stirring is not particularly required in the present invention.
After the first mixture is obtained, the temperature is reduced to a second temperature, and the first mixture, the shea non-saponified substance, the acetyl gingerol and the esterified plant polyphenol are mixed for the second time to obtain a second mixture.
In the present invention, the second temperature is preferably 65 to 75 ℃, more preferably 70 ℃.
In the present invention, the incubation time of the second mixing is 10 to 15 minutes, more preferably 10 minutes.
In the present invention, the second mixing is preferably performed under stirring, and the rotation speed of the stirring is not particularly required in the present invention.
After the second mixture is obtained, the temperature is reduced to a third temperature, and the second mixture, jojoba seed oil, flaxseed, celery extract and teprenone are mixed for the third time to obtain a third mixture.
In the present invention, the third temperature is preferably 40 to 50 ℃, preferably 45 ℃.
In the present invention, the incubation time of the third mixture is preferably 5 to 10 minutes, more preferably 5 minutes.
In the present invention, the third mixing is preferably performed under stirring, and the rotation speed of the stirring is not particularly required in the present invention.
After the third mixture is obtained, the temperature is reduced to room temperature, and the third mixture, the compound plant essential oil, the perilla seed oil, the cucumber seed oil, the watermelon seed oil, the peony seed oil, the oat seed oil, the olive squalane and the natural tocopherol are fourth mixed to obtain the anti-aging anhydrous essential oil.
In the present invention, the incubation time of the fourth mixing is preferably 60 to 80 minutes, more preferably 60 minutes.
In the present invention, the fourth mixing is preferably performed under stirring, and the rotation speed of the stirring is not particularly required in the present invention.
In the present invention, the fourth mixture is preferably a clear transparent oil, free of any particulate matter or solid insoluble matter.
The fourth mixture is preferably filtered to obtain the anti-aging anhydrous essential oil.
The technical solutions provided by the present invention are described in detail below with reference to the drawings and examples for further illustrating the present invention, but they should not be construed as limiting the scope of the present invention.
The sources of the raw materials employed in the practice of the present invention are shown in table 1.
Table 1 sources of the raw materials used in the examples are shown in Table 1
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Example 1
The anti-aging anhydrous essential oil suitable for the sensitive weak skin is prepared by adopting the raw materials in table 2 and the mass parts of the raw materials in the example.
TABLE 2 raw materials used in EXAMPLE 1 and parts by mass of the raw materials
The preparation method comprises the following steps:
1) Adding dimethyl methoxy phenylpropyl dihydropyranol, stearyl glycyrrhetinate, oryzanol and glycerol tri (ethylhexanoate) to 85 ℃ and stirring at uniform speed for 10min until the three components are completely dissolved and mixed uniformly;
2) Cooling the mixture obtained in the step 1) to 70 ℃, adding the non-saponified material of the shea butter and the acetyl gingerol as well as the esterified plant polyphenol, stirring at a constant speed, dissolving and mixing uniformly;
3) Cooling the mixture obtained in the step 2) to 45 ℃, adding jojoba seed oil, flaxseed, celery extract and teprenone, and uniformly stirring and mixing at uniform speed;
4) Cooling the mixture obtained in the step 3) to room temperature, adding the rest components, stirring at constant speed for 60min until the mixed system finally presents a clear and transparent oil liquid state without any particulate matters or solid insoluble matters, and finally filtering out the pot to obtain the anti-aging anhydrous essential oil.
Example 2
The anti-aging anhydrous essential oil suitable for the sensitive weak skin is prepared by adopting the raw materials in table 3 and the mass parts of the raw materials in the embodiment.
TABLE 3 raw materials used in EXAMPLE 2 and parts by mass of the raw materials
| Raw material name | Parts by mass |
| Glycerol tris (ethylhexanoate) | 9 |
| Dimethylmethoxy phenylpropanoid dihydropyranols | 0.02 |
| Stearyl alcohol glycyrrhetinate | 0.15 |
| Oryzanol | 0.3 |
| Non-saponified material of shea butter | 1 |
| Acetyl gingerol | 0.8 |
| Palmitoyl tea extract | 0.5 |
| Cortex Pini extract | 0.5 |
| Jojoba seed oil | 27 |
| Linseed and celery extracts | 3.2 |
| Teprenone | 1 |
| Supercritical perilla seed oil | 28 |
| Supercritical cucumber seed oil | 3 |
| Supercritical watermelon seed oil | 8 |
| Supercritical peony seed oil | 5 |
| Supercritical oat oil | 2.5 |
| Olive squalane | 7.5 |
| Natural tocopherol | 1.2 |
| Supercritical osmanthus essential oil | 0.68 |
| White magnolia essential oil | 0.3 |
| Emulsifiable concentrate | 0.15 |
| Myrrh essential oil | 0.1 |
| Italian permanent flower essential oil | 0.1 |
The preparation method is the same as in example 1.
Example 3
The anti-aging anhydrous essential oil suitable for the sensitive weak skin is prepared by adopting the raw materials in table 4 and the mass parts of the raw materials in the example.
TABLE 4 raw materials used in EXAMPLE 3 and parts by mass of the raw materials
| Raw material name | Parts by mass |
| Glycerol tris (ethylhexanoate) | 8.5 |
| Dimethylmethoxy phenylpropanoid dihydropyranols | 0.03 |
| Stearyl alcohol glycyrrhetinate | 0.2 |
| Oryzanol | 0.15 |
| Non-saponified material of shea butter | 0.8 |
| Acetyl gingerol | 0.5 |
| Palmitoyl tea extract | 0.8 |
| Cortex Pini extract | 0.8 |
| Jojoba seed oil | 30 |
| Linseed and celery extracts | 2.5 |
| Teprenone | 0.5 |
| Supercritical perilla seed oil | 29 |
| Supercritical cucumber seed oil | 2 |
| Supercritical watermelon seed oil | 5 |
| Supercritical peony seed oil | 6.37 |
| Supercritical oat oil | 2 |
| Olive squalane | 8 |
| Natural tocopherol | 0.75 |
| Supercritical osmanthus essential oil | 1.2 |
| White magnolia essential oil | 0.2 |
| Emulsifiable concentrate | 0.2 |
| Myrrh essential oil | 0.2 |
| Italian permanent flower essential oil | 0.3 |
The preparation method is the same as in example 1.
Example 4
The anti-aging anhydrous essential oil suitable for the sensitive weak skin is prepared by adopting the raw materials in table 5 and the mass parts of the raw materials in the example.
TABLE 5 raw materials used in EXAMPLE 4 and parts by mass of the raw materials
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The preparation method is the same as in example 1.
Example 5
The anti-aging anhydrous essential oil suitable for the sensitive weak skin is prepared by adopting the raw materials in table 6 and the mass parts of the raw materials in the example.
TABLE 6 raw materials used in EXAMPLE 5 and parts by mass of the raw materials
| Raw material name | Parts by mass |
| Glycerol tris (ethylhexanoate) | 8 |
| Dimethylmethoxy phenylpropanoid dihydropyranols | 0.04 |
| Stearyl alcohol glycyrrhetinate | 0.5 |
| Oryzanol | 0.15 |
| Non-saponified material of shea butter | 1.5 |
| Acetyl gingerol | 2 |
| Palmitoyl tea extract | 1 |
| Cortex Pini extract | 1 |
| Jojoba seed oil | 26.5 |
| Linseed and celery extracts | 5 |
| Teprenone | 1.5 |
| Supercritical perilla seed oil | 30 |
| Supercritical cucumber seed oil | 1.3 |
| Supercritical watermelon seed oil | 5 |
| Supercritical peony seed oil | 6.2 |
| Supercritical oat oil | 2 |
| Olive squalane | 5.76 |
| Natural tocopherol | 0.5 |
| Supercritical osmanthus essential oil | 1 |
| White magnolia essential oil | 0.2 |
| Emulsifiable concentrate | 0.15 |
| Myrrh essential oil | 0.15 |
| Italian permanent flower essential oil | 0.5 |
The preparation method is the same as in example 1.
Comparative example 1
The comparative example uses the raw materials in table 7 and the mass parts of the raw materials to prepare the anti-aging anhydrous essential oil suitable for the sensitive weak skin.
TABLE 7 raw materials used in comparative example 1 and parts by mass of the raw materials
The preparation method comprises the following steps:
1) Adding dimethyl methoxy phenylpropanol, oryzanol and glycerol (ethyl hexanoate) to 85 ℃ and stirring at uniform speed for 10min until the three components are completely dissolved and mixed uniformly;
2) Cooling the mixture obtained in the step 1) to 70 ℃, adding the non-saponified material of the shea butter and the esterified plant polyphenol, stirring at a constant speed, dissolving and mixing uniformly;
3) Cooling the mixture obtained in the step 2) to 45 ℃, adding jojoba seed oil, flaxseed and celery extract, uniformly stirring and mixing at uniform speed;
4) Cooling the mixture obtained in the step 3) to room temperature, adding the rest components, stirring at constant speed for 60min until the mixed system finally presents a clear and transparent oil liquid state without any particulate matters or solid insoluble matters, and finally filtering out the pot to obtain the anti-aging anhydrous essential oil.
Comparative example 2
The comparative example uses the raw materials in table 8 and the mass parts of the raw materials to prepare the anti-aging anhydrous essential oil suitable for the sensitive weak skin.
TABLE 8 raw materials used in comparative example 2 and parts by mass of the raw materials
The preparation method comprises the following steps:
1) Adding dimethyl methoxy phenylpropanol, oryzanol and glycerol (ethyl hexanoate) to 85 ℃ and stirring at uniform speed for 10min until the three components are completely dissolved and mixed uniformly;
2) Cooling the mixture obtained in the step 1) to 70 ℃, adding the non-saponified material of the shea butter and the acetyl gingerol, stirring at a constant speed, dissolving and mixing uniformly;
3) Cooling the mixture obtained in the step 2) to 45 ℃, adding jojoba seed oil, flaxseed, celery extract and teprenone, and uniformly stirring and mixing at uniform speed;
4) Cooling the mixture obtained in the step 3) to room temperature, adding the rest components, stirring at constant speed for 60min until the mixed system finally presents a clear and transparent oil liquid state without any particulate matters or solid insoluble matters, and finally filtering out the pot to obtain the anti-aging anhydrous essential oil.
Comparative example 3
The comparative example uses the raw materials in table 9 and the mass parts of the raw materials to prepare the anti-aging facial essential oil suitable for the sensitive weak skin.
TABLE 9 raw materials used in comparative example 3 and parts by mass of the raw materials
| Raw material name | Parts by mass |
| Glycerol tris (ethylhexanoate) | 7 |
| Dimethylmethoxy phenylpropanoid dihydropyranols | 0.05 |
| Stearyl alcohol glycyrrhetinate | 0.3 |
| Oryzanol | 0.5 |
| Non-saponified material of shea butter | 0.5 |
| Acetyl gingerol | 1.2 |
| Palmitoyl tea extract | 1 |
| Cortex Pini extract | 1 |
| Jojoba seed oil | 25.75 |
| Linseed and celery extracts | 3 |
| Teprenone | 0.5 |
| Supercritical perilla seed oil | 31.5 |
| Supercritical cucumber seed oil | 2.5 |
| Supercritical watermelon seed oil | 5 |
| Supercritical peony seed oil | 6.2 |
| Supercritical oat oil | 2.5 |
| Olive squalane | 10 |
| Natural tocopherol | 1 |
| Emulsifiable concentrate | 0.2 |
| Myrrh essential oil | 0.3 |
The preparation method comprises the following steps:
1) Adding dimethyl methoxy phenylpropanol, oryzanol and glycerol (ethyl hexanoate) to 85 ℃ and stirring at uniform speed for 10min until the three components are completely dissolved and mixed uniformly;
2) Cooling the mixture obtained in the step 1) to 70 ℃, adding the non-saponified material of the shea butter and the acetyl gingerol as well as the esterified plant polyphenol, stirring at a constant speed, dissolving and mixing uniformly;
3) Cooling the mixture obtained in the step 2) to 45 ℃, adding jojoba seed oil, flaxseed, celery extract and teprenone, and uniformly stirring and mixing at uniform speed;
4) Cooling the mixture obtained in the step 3) to room temperature, adding the rest components, stirring at constant speed for 60min until the mixed system finally presents a clear and transparent oil liquid state without any particulate matters or solid insoluble matters, and finally filtering out the pot to obtain the anti-aging anhydrous essential oil.
Test case
The anti-aging anhydrous essential oil prepared in the example 1, the comparative example 2 and the comparative example 3 is used for trial, and the trial method is as follows: selecting 10 Chinese healthy female subjects with facial skin accompanied by problems of wrinkles, textures, pores, purple matters and the like, and 2 male subjects, wherein subjects 1, subjects 3 to 6 and subjects 9 to 11 use the product prepared in the embodiment 1 of the invention, subject 2 uses the product prepared in the comparative example 1 of the invention, subject 7 uses the product prepared in the comparative example 2 of the invention, and subjects 8 and 12 use the product prepared in the comparative example 3 of the invention; subject on-the-face trialThe face photographs are taken before testing the product and after trial for 1 week and 2 weeks, and the skin wrinkles, textures, pores and purple improvement conditions are analyzed, wherein the face photographs are taken by using a VISIA-CR (visible light source-CR) method: face front, left 45 degrees, right 45 degrees. Wrinkles exemplified by fine lines under the eyes, skin wrinkles and purple conditions employ ViScan VC98 (Courge&Khazaka, germany), the corresponding skin index values were extracted using software carried by the ViScan VC98 instrument, and the test results are shown in tables 10 to 11 and fig. 1 to 47, in tables 10 to 11, W 0 Representing pre-test data, W 1 Represents data after 1 week of use, W 2 The data after 2 weeks of use are represented, the decrease rate of the test value is a negative value, and the more the decrease is, the better the improvement effect of the corresponding index is represented.
The temperature of the trial environment is 20.5-21.8 ℃, the relative humidity is 45-54%, and the trial method comprises the following steps: the anti-aging anhydrous essential oil product of the embodiment 1 is used for the whole face after the face is cleaned after the trial is carried out once in the morning and evening every day, the usage amount of each time is 0.5-1 g, and the anti-aging anhydrous essential oil product is gently smeared and massaged until the anti-aging anhydrous essential oil is thoroughly absorbed.
Table 10 subject 1, subjects 3 to 6, subjects 9 to 10, left side face change data after the product was prepared using example 1 of the present invention
Table 11 subject 1, subjects 3 to 6, subjects 9 to 10, right side face change data after the product was prepared using example 1 of the present invention
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Table 12 subject 2 left side face change data after preparing a product using comparative example 1 of the present invention
Table 13 subject 2 data on right side face change after preparing the product using comparative example 1 of the present invention
Table 14 subject 7 left side face change data after preparing a product using comparative example 2 of the present invention
Table 15 subject 7 right side change data after preparing the product using comparative example 2 of the present invention
Table 16 data on left side face change after subject 8, subject 12 prepared a product using comparative example 3 of the present invention
Table 17 subject 8 and subject 12 data on right side face change after preparing the product using comparative example 3 of the present invention
As can be seen from tables 10-17 and figures 1-47, the anti-aging anhydrous essential oil provided by the invention adopts compound plant essential oil, a plurality of compound solid fat-soluble active substances, teprenone, linseed rich in cyclic peptide and senkyunolide, and celery extract, compound plant oil, olive squalane, natural tocopherol and triglyceride (ethyl caproic acid) ester to be matched, fully aims at different types of free radicals, can absorb ultraviolet rays of a special wave band, has the effects of resisting oxidation, resisting saccharification and resisting photo-aging, and accurately solves the problems of coarse pores, rough skin texture, unsmooth skin blood circulation, tarnish and matt skin and the like which are puzzled to the public. The skin is compact, fine, smooth and elastic, the skin color is white, clear and transparent, and the healthy halation gloss is presented, as can be obtained from the table 10 and the table 11, and the wrinkles, textures and pore purple of the left face and the right face of the subject 1, the subject 3 to 6 and the subject 9 to 10 after the product is prepared by using the embodiment 1 of the invention are obviously improved; as can be seen from tables 12 and 13, subject 2 using the product of comparative example 1, the improvement of wrinkles (change rate-4.17%) and texture (change rate-4.72) of the right face of subject 2 was not significant due to the absence of teprenone and acetozingibrone; subject 7 using the product prepared in comparative example 2 of the present invention, since the product of comparative example 2 does not contain palmitoyl tea extract and coastal pine bark extract, although the anti-wrinkle effect of the left and right faces is good, the texture (change rate 4.93%) and pores (change rate-2.26) of the right face of subject 7 are not significantly improved; subject 8, subject 12 prepared products using comparative example 3 of the present invention, since the product of comparative example 2 did not contain flaxseed and celery extract and supercritical osmanthus essential oil, although subject 8 had facial purple improved from better, pores of subject 8 and subject 12 improved poorly.
The test results of the products prepared in examples 2 to 5 were similar to example 1.
Although the foregoing embodiments have been described in some, but not all embodiments of the invention, other embodiments may be obtained according to the present embodiments without departing from the scope of the invention.
Claims (10)
1. The anti-aging anhydrous essential oil is characterized by comprising the following components in parts by weight:
0.5 to 3 parts of compound plant essential oil, 0.5 to 8 parts of compound solid fat-soluble active matter, 0.01 to 2 parts of teprenone, 1 to 5 parts of flaxseed and celery extract, 25.5 to 92 parts of compound plant oil, 5 to 12 parts of olive squalane, 0.1 to 1.2 parts of natural tocopherol, 5 to 9.5 parts of triglyceride (ethyl caproic acid) ester and 0.01 to 0.05 part of dimethyl methoxy phenylpropanol;
the compound plant essential oil comprises osmanthus essential oil, permanent flower essential oil, frankincense essential oil and myrrh essential oil;
the compound solid fat-soluble active substances comprise stearyl glycyrrhetinate, oryzanol, shea butter non-saponified substances, acetyl gingerol and esterified plant polyphenol; the esterified plant polyphenol comprises palmitoyl tea extract and/or coastal pine extract;
The compound vegetable oil comprises jojoba seed oil, perilla seed oil, cucumber seed oil, watermelon seed oil, peony seed oil and oat seed oil.
2. The anti-aging anhydrous essential oil of claim 1, wherein the compound plant essential oil comprises the following components in parts by mass:
0.2 to 1.2 portions of osmanthus essential oil, 0.1 to 0.8 portion of permanent flower essential oil, 0.1 to 0.2 portion of milk essential oil and 0.1 to 0.3 portion of myrrh essential oil.
3. The anti-aging anhydrous essential oil of claim 1, wherein the compound plant essential oil further comprises a magnolia alba essential oil.
4. The anti-aging anhydrous essential oil according to claim 2 or 3, wherein the compound plant essential oil further comprises 0.01-0.25 part of magnolia alba essential oil in parts by weight.
5. The anti-aging anhydrous essential oil of claim 1, wherein the compound vegetable oil comprises the following components in parts by mass:
10-30 parts of jojoba seed oil, 10-35 parts of perilla seed oil, 1-5 parts of cucumber seed oil, 1.5-8 parts of watermelon seed oil, 2-9 parts of peony seed oil and 1-5 parts of oat seed oil.
6. The anti-aging anhydrous essential oil of claim 1, wherein the compound solid fat-soluble active substance comprises the following components in parts by mass:
0.05 to 0.5 part of stearyl alcohol glycyrrhetinate, 0.05 to 0.5 part of oryzanol, 0.1 to 3 parts of shea butter non-saponified matters, 0.1 to 2 parts of acetyl gingerol and 0.2 to 2 parts of esterified plant polyphenol.
7. The anti-aging anhydrous essential oil according to claim 1 or 6, wherein the esterified plant polyphenol comprises palmitoyl tea extract and coastal pine extract, and the mass ratio of palmitoyl tea extract to coastal pine extract is (0.5-1): 0.5-1.
8. The process for preparing an anti-aging anhydrous essential oil according to any one of claims 1 to 7, characterized by comprising the steps of:
under a first temperature condition, first mixing dimethyl methoxy phenylpropanoid dihydropyran alcohol, stearyl glycyrrhetinate, oryzanol and triglyceride (ethylhexanoic acid) ester to obtain a first mixture;
cooling to a second temperature, and mixing the first mixture, the non-saponified shea butter, the acetyl gingerol and the esterified plant polyphenol for the second time to obtain a second mixture;
cooling to a third temperature, and third mixing the second mixture, jojoba seed oil, flaxseed, celery extract and teprenone to obtain a third mixture;
cooling to room temperature, and fourth mixing the third mixture, the compound plant essential oil, the perilla seed oil, the cucumber seed oil, the watermelon seed oil, the peony seed oil, the oat seed oil, the olive squalane and the natural tocopherol to obtain the anti-aging anhydrous essential oil.
9. The method of claim 8, wherein the first temperature is 80-90 ℃; the second temperature is 65-75 ℃; the third temperature is 40-50 ℃.
10. The method of claim 9, wherein the first mixing is performed for a holding time of 10 to 15 minutes; the heat preservation time of the second mixing is 10-15 min; the heat preservation time of the third mixing is 5-10 min; the fourth mixing heat preservation time is 60-80 min.
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