CN117599148A - Foot-use Chinese and western medicine combination medicine and preparation method thereof - Google Patents
Foot-use Chinese and western medicine combination medicine and preparation method thereof Download PDFInfo
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- CN117599148A CN117599148A CN202311708695.4A CN202311708695A CN117599148A CN 117599148 A CN117599148 A CN 117599148A CN 202311708695 A CN202311708695 A CN 202311708695A CN 117599148 A CN117599148 A CN 117599148A
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Abstract
The invention discloses a foot Chinese and western medicine combined medicament, which comprises the following raw material medicines in parts by weight: 7-10 parts of wormwood, 8-10 parts of dandelion, 5-10 parts of corn silk, 8-10 parts of mint, 8-10 parts of honeysuckle, 8-10 parts of bletilla striata, 5-10 parts of ginger, 7-10 parts of cortex moutan, 8-10 parts of garden balsam stem, 8-10 parts of stephania tetrandra, 12-15 parts of nux vomica and 5-10 parts of clove. The foot Chinese and western medicine combination medicine has the effects of detumescence, relaxing tendons, dredging collaterals, maintaining skin, promoting sleep, promoting heart and kidney intersection, enhancing immunity, relieving pain of patients and the like, can effectively solve the problem of lack of the market of the foot smearing agent, and has the characteristics of simple formula, convenience in carrying, small side effect and good effect, and can be used in daily life.
Description
Technical Field
The invention belongs to the technical field of combination of Chinese and western medicines, and particularly relates to a foot-use Chinese and western medicine combination and a preparation method thereof.
Background
The second heart of the human body is called the foot, and each organ has a specific reflex area on the foot, and half of the meridians connecting with viscera of the human body start from the foot, so that the foot bath health care therapy relies on the stimulation of medicaments on the reflex areas of the sole to promote the blood circulation of the human body and lead pharmacological effects to reach focus.
Most patients suffering from foot injuries and foot skin diseases face long-term pain, so that the patients and their families bring great mental pain and life pressure to daily work and life. In addition, the number of patients suffering from insomnia, low immunity and the like caused by epidemic situation and the like is high, and the patients bring great influence to the life of common people.
Provides a foot medicament which is convenient to use and can be widely popularized, and is one of the main ways for solving the trouble of patients with foot diseases, insomnia, low immunity and the like.
Disclosure of Invention
The invention aims to solve the technical problem of providing a foot Chinese and western medicine combination medicine and a preparation method thereof aiming at the defects of the prior art. The foot Chinese and western medicine combination has the effects of detumescence, relaxing tendons, dredging collaterals, maintaining skin, promoting sleep, promoting heart and kidney intersection, enhancing immunity, relieving pain of patients and the like, can effectively solve the problem of lack of the current foot smearing agent market, and has the characteristics of simple formula, convenience in carrying, small side effect and good effect, and can be used in daily life.
In order to solve the technical problems, the invention adopts the following technical scheme: the foot Chinese and western medicine combination is characterized by comprising the following raw materials in parts by weight: 7-10 parts of wormwood, 8-10 parts of dandelion, 5-10 parts of corn silk, 8-10 parts of mint, 8-10 parts of honeysuckle, 8-10 parts of bletilla striata, 5-10 parts of ginger, 7-10 parts of cortex moutan, 8-10 parts of garden balsam stem, 8-10 parts of stephania tetrandra, 12-15 parts of nux vomica and 5-10 parts of clove.
The foot Chinese and western medicine combination is characterized in that the foot Chinese and western medicine combination is in the form of a smearing agent or a decoction.
The above-mentioned a combination of Chinese and western medicines for foot, wherein, when the formulation of the combination of Chinese and western medicines for foot is a smearing agent, the raw materials of the combination of Chinese and western medicines for foot also include: 10 parts of glycerin, 10 parts of vitamin E, 5 parts of sodium bicarbonate, 10 parts of sodium sulfate, 5 parts of sodium lauryl sulfate, 1 part of zinc oxide, 10 parts of yellow vaseline and 10 parts of essence.
The above-mentioned a combination of traditional chinese medicine and western medicine for foot, when the formulation of combination of traditional chinese medicine and western medicine for foot is the decoction, the raw materials of combination of traditional chinese medicine and western medicine for foot still include: 10 parts of mineral salt, 10 parts of glycerin, 15 parts of vitamin E, 10 parts of sodium bicarbonate, 10 parts of sodium sulfate, 10 parts of sodium lauryl sulfate and 10 parts of essence.
The foot Chinese and western medicine combination is characterized in that the mineral salt is borate.
In addition, the invention also provides a method for preparing the foot Chinese and western medicine combination, which is characterized in that,
when the dosage form of the combination of the Chinese and western medicines for foot is a coating agent, the method comprises the following steps: pulverizing the raw materials, soaking the pulverized raw materials in ethanol solution containing glycerol, vitamin E, sodium bicarbonate, sodium sulfate, sodium lauryl sulfate, zinc oxide, yellow vaseline and essence for 7-30 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain a coating agent;
when the dosage form of the foot Chinese and western medicine combination is decoction, the method comprises the following steps: pulverizing the raw materials, soaking the pulverized raw materials in ethanol solution containing glycerol, vitamin E, sodium bicarbonate, sodium sulfate, sodium laurylsulfate and essence for 7-30 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain decoction.
The method is characterized in that the volume concentration of the ethanol solution is 55%.
The method is characterized in that the ratio of the volume of the ethanol solution to the weight of the bulk drug is (4-10): 1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g.
The weight parts of the invention can be the weight units of gram, two weight parts, jin weight parts, kg weight parts, ton weight parts and the like.
Compared with the prior art, the invention has the following advantages:
1. the foot Chinese and western medicine combination medicine has the effects of detumescence, relaxing tendons, dredging collaterals, maintaining skin, promoting sleep, promoting heart and kidney intersection, enhancing immunity, relieving pain of patients and the like, can effectively solve the problem of lack of the market of the foot smearing agent, and has the characteristics of simple formula, convenience in carrying, small side effect and good effect, and can be used in daily life.
2. The compatibility of the combination of the Chinese and western medicines for foot use is as follows: dandelion, honeysuckle, bletilla striata and clove, which are used as monarch drugs for enhancing immunity, preserving skin, diminishing inflammation and relieving pain; the wormwood, the cortex moutan, the garden balsam stem and the ginger have the effects of promoting blood circulation by removing blood stasis, relaxing tendons and activating collaterals, and are ministerial drugs, and the dandelion is matched with the honeysuckle, so that the blood circulation is enhanced and the swelling is reduced; peppermint is used for refreshing and cleaning skin, corn silk is used for promoting heart and kidney intersection, stephania tetrandra is used for relaxing smooth muscle, relieving swelling and pain, and is helpful for sleeping, and dandelion, honeysuckle, cortex moutan and garden balsam stem are matched to achieve further effects of relieving swelling and pain, improving heart and kidney intersection and being helpful for sleeping; the nux vomica is used as a guiding drug for dredging collaterals and relieving pain, and is matched with dandelion, honeysuckle, garden balsam stem and stephania tetrandra to further achieve the effects of dredging collaterals and relieving pain and promoting heart-kidney intersection.
The combination of mineral salt, glycerin, vitamin E, sodium bicarbonate, sodium sulfate, sodium lauryl sulfate and (daily) essence achieves the effects of cleaning and caring skin, diminishing inflammation and sterilizing, removing horny layer, promoting skin metabolism, and refreshing and moisturizing skin.
Twelve traditional Chinese medicines are combined with auxiliary materials, and the monarch, minister, assistant and guide are clear in work division, and the effects of detumescence, relaxing tendons, dredging collaterals, maintaining skin, promoting sleep, promoting heart-kidney intersection and enhancing immunity are achieved.
3. In the foot Chinese and western medicine combination medicine, dandelion, honeysuckle and bletilla striata have the effects of activating blood, relieving swelling and pain, maintaining skin and improving immunity, and are beneficial to improving the medicine effect.
4. The foot Chinese and western medicine combination medicine provided by the invention is in the form of foot bath decoction and smearing preparation, has the characteristics of convenience in carrying and use, and does not influence normal work and life of patients.
The technical scheme of the invention is further described in detail below with reference to the examples.
Detailed Description
Example 1
The embodiment provides a foot-used Chinese and western medicine combination drug, which is prepared from the following raw materials: 10g of wormwood, 10g of dandelion, 10g of corn silk, 10g of mint, 10g of honeysuckle, 10g of bletilla striata, 10g of ginger, 10g of cortex moutan, 10g of garden balsam stem, 10g of stephania tetrandra, 15g of nux vomica and 10g of clove.
The dosage form of the foot Chinese and western medicine combination medicine in the embodiment is a smearing agent.
In the foot Chinese and western medicine combination medicine, the raw materials further comprise: 10g of glycerin, 10g of vitamin E, 5g of sodium bicarbonate, 10g of sodium sulfate, 5g of sodium lauryl sulfate, 1 g of zinc oxide, 10g of yellow vaseline and 10g of essence.
The embodiment also provides a method for preparing the foot Chinese and western medicine combination, which comprises the following steps:
pulverizing the raw materials, soaking in ethanol solution for 24 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain the foot Chinese and western medicine combination; the ratio of the volume of the ethanol solution to the weight of the bulk drug is 6:1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g; the volume concentration of the ethanol solution was 55%.
Example 2
The embodiment provides a foot-used Chinese and western medicine combination drug, which is prepared from the following raw materials: 7 g of wormwood, 9 g of dandelion, 5g of corn silk, 8 g of mint, 8 g of honeysuckle, 8 g of bletilla striata, 7 g of ginger, 7 g of cortex moutan, 8 g of garden balsam stem, 8 g of stephania tetrandra, 12 g of nux vomica and 8 g of clove.
The dosage form of the foot Chinese and western medicine combination medicine in the embodiment is a smearing agent.
In the foot Chinese and western medicine combination medicine, the raw materials further comprise: 10g of glycerin, 10g of vitamin E, 5g of sodium bicarbonate, 10g of sodium sulfate, 5g of sodium lauryl sulfate, 1 g of zinc oxide, 10g of yellow vaseline and 10g of essence.
The embodiment also provides a method for preparing the foot Chinese and western medicine combination, which comprises the following steps:
pulverizing the raw materials, soaking in ethanol solution for 7 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain the foot Chinese and western medicine combination; the ratio of the volume of the ethanol solution to the weight of the bulk drug is 10:1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g; the volume concentration of the ethanol solution was 55%.
The efficacy of this example was substantially the same as that of example 1.
Example 3
The embodiment provides a foot-used Chinese and western medicine combination drug, which is prepared from the following raw materials: 8 g of wormwood, 8 g of dandelion, 7 g of corn silk, 9 g of mint, 9 g of honeysuckle, 9 g of bletilla striata, 5g of ginger, 8 g of cortex moutan, 9 g of garden balsam stem, 9 g of stephania tetrandra, 13 g of nux vomica and 5g of clove.
The dosage form of the foot Chinese and western medicine combination medicine in the embodiment is a smearing agent.
In the foot Chinese and western medicine combination medicine, the raw materials further comprise: 10g of glycerin, 10g of vitamin E, 5g of sodium bicarbonate, 10g of sodium sulfate, 5g of sodium lauryl sulfate, 1 g of zinc oxide, 10g of yellow vaseline and 10g of essence.
The embodiment also provides a method for preparing the foot Chinese and western medicine combination, which comprises the following steps:
pulverizing the raw materials, soaking in ethanol solution for 30 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain the foot Chinese and western medicine combination; the ratio of the volume of the ethanol solution to the weight of the bulk drug is 4:1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g; the volume concentration of the ethanol solution was 55%.
The efficacy of this example was substantially the same as that of example 1.
Example 4
The embodiment provides a foot-used Chinese and western medicine combination drug, which is prepared from the following raw materials: 10g of wormwood, 10g of dandelion, 10g of corn silk, 10g of mint, 10g of honeysuckle, 10g of bletilla striata, 10g of ginger, 10g of cortex moutan, 10g of garden balsam stem, 10g of stephania tetrandra, 15g of nux vomica and 10g of clove.
The dosage form of the foot Chinese and western medicine combination medicine in the embodiment is decoction.
In the foot Chinese and western medicine combination medicine, the raw materials further comprise: 10g of mineral salt, 10g of glycerin, 15g of vitamin E, 10g of sodium bicarbonate, 10g of sodium sulfate, 10g of sodium lauryl sulfate and 10g of essence; the mineral salt is borax.
The embodiment also provides a method for preparing the foot Chinese and western medicine combination, which comprises the following steps:
pulverizing the raw materials, soaking in ethanol solution with glycerol, vitamins, sodium bicarbonate, sodium sulfate, sodium laurylsulfate and essence for 25 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain decoction; the ratio of the volume of the ethanol solution to the weight of the bulk drug is 5:1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g; the volume concentration of the ethanol solution was 55%.
When the decoction is used as a combination of Chinese and western medicines for foot, the decoction is boiled in water, and mineral salt is added until the water temperature is reduced to below 45 ℃ to perform foot bath; the mass of the water is 20-25 times of that of the decoction.
Example 5
The embodiment provides a foot-used Chinese and western medicine combination drug, which is prepared from the following raw materials: 7 g of wormwood, 9 g of dandelion, 5g of corn silk, 8 g of mint, 8 g of honeysuckle, 8 g of bletilla striata, 8 g of ginger, 7 g of cortex moutan, 8 g of garden balsam stem, 8 g of stephania tetrandra, 12 g of nux vomica and 7 g of clove.
The dosage form of the foot Chinese and western medicine combination medicine in the embodiment is decoction.
In the foot Chinese and western medicine combination medicine, the raw materials further comprise: 10g of mineral salt, 10g of glycerin, 15g of vitamin E, 10g of sodium bicarbonate, 10g of sodium sulfate, 10g of sodium lauryl sulfate and 10g of essence; the mineral salt is borax.
The embodiment also provides a method for preparing the foot Chinese and western medicine combination, which comprises the following steps:
pulverizing the raw materials, soaking in ethanol solution with glycerol, vitamins, sodium bicarbonate, sodium sulfate, sodium laurylsulfate and essence for 7 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain decoction; the ratio of the volume of the ethanol solution to the weight of the bulk drug is 10:1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g; the volume concentration of the ethanol solution was 55%.
When the decoction is used as a combination of Chinese and western medicines for foot, the decoction is boiled in water, and mineral salt is added until the water temperature is reduced to below 45 ℃ to perform foot bath; the mass of the water is 20-25 times of that of the decoction.
The efficacy of this example is substantially the same as that of example 4.
Example 6
The embodiment provides a foot-used Chinese and western medicine combination drug, which is prepared from the following raw materials: 9 g of wormwood, 8 g of dandelion, 7 g of corn silk, 9 g of mint, 9 g of honeysuckle, 9 g of bletilla striata, 5g of ginger, 9 g of cortex moutan, 9 g of garden balsam stem, 9 g of stephania tetrandra, 14 g of nux vomica and 5g of clove.
The dosage form of the foot Chinese and western medicine combination medicine in the embodiment is decoction.
In the foot Chinese and western medicine combination medicine, the raw materials further comprise: 10g of mineral salt, 10g of glycerin, 15g of vitamin E, 10g of sodium bicarbonate, 10g of sodium sulfate, 10g of sodium lauryl sulfate and 10g of essence; the mineral salt is borax.
The embodiment also provides a method for preparing the foot Chinese and western medicine combination, which comprises the following steps:
pulverizing the raw materials, soaking in ethanol solution with glycerol, vitamins, sodium bicarbonate, sodium sulfate, sodium laurylsulfate and essence for 30 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain decoction; the ratio of the volume of the ethanol solution to the weight of the bulk drug is 4:1, wherein the unit of the volume of the ethanol solution is mL, and the unit of the weight of the bulk drug is g; the volume concentration of the ethanol solution was 55%.
When the decoction is used as a combination of Chinese and western medicines for foot, the decoction is boiled in water, and mineral salt is added until the water temperature is reduced to below 45 ℃ to perform foot bath; the mass of the water is 20-25 times of that of the decoction. The volume concentration of the ethanol solution was 55%.
The efficacy of this example is substantially the same as that of example 4.
Description of typical cases:
case 1: huang Mou, women, 38 years old, the ankle sprain part is remarkably swollen and extremely painful due to climbing mountain, the smearing preparation of the embodiment 1 of the invention is immediately used for smearing the part, the swelling area is about 30mm multiplied by 20mm, the smearing dosage is about 5g, the pain is remarkably relieved after 5 minutes, the part is slightly swollen after 12 hours, the smearing preparation is reset and used continuously, 4 to 5 times per day, and the normal walking is recovered after 3 days.
Case 2: meng Mou when the decoction of example 4 of the present invention is used 5 times for 5 days, the chap of foot skin disappears, the skin of foot is smooth, and the symptoms of itching disappear; the specific using method comprises the following steps: boiling the decoction in water, adding mineral salt, and cooling to below 45deg.C to obtain foot bath; the mass of the water is 20-25 times of that of the decoction.
Case 3: ma Mou A, 36 years old, anxiety, cerebral neurasthenia, insomnia, 10 times of foot bath with the decoction of the embodiment 4 of the invention, 5 times of 5 days old, and 10 times of 10 days old, the insomnia symptom is greatly relieved, and the specific use method is the same as that of case 2.
Case 4: wang Mou A, 42 years old, lumbar muscle strain and lumbar muscle ligament sprain, the application of the coating agent of the embodiment 1 of the invention is carried out to locally, the wound area is about 35mm multiplied by 25mm, the pain is obviously relieved after the application amount is about 10g and 20min, the pain is slightly painful locally after 12 hours, the application is continued for 4 to 5 times per day, and the normal state is recovered after 2 days.
General clinical data: 160 patients are treated by the coating agent of the embodiment 1 or the decoction of the embodiment 4 for foot bath, wherein the coating agent is used for 4-5 times daily, and the decoction is used for 1 time daily.
The soft tissue injury detumescence and analgesia efficacy standard is divided into three grades: obvious effect, effective and ineffective.
The effect is shown: the swelling completely disappeared and the pain disappeared.
The method is effective: the swelling resolved significantly and the pain was reduced.
Invalidation: the swelling resolved less clearly and the pain did not decrease.
Skin care efficacy criteria are divided into three classes: obvious effect, effective and ineffective.
The effect is shown: the skin of the foot is fine, smooth and ruddy, the feet are warm, and the foot is not easy to cool.
The method is effective: the skin of the foot is not dry. Itching is accompanied by foot odor.
Invalidation: itching, dryness and no luster of foot skin.
The standard of the curative effect of relaxing tendons and activating collaterals is divided into three grades: obvious effect, effective and ineffective.
The effect is shown: the swelling completely disappeared and the pain disappeared.
The method is effective: the swelling resolved significantly and the pain was reduced.
Invalidation: the swelling resolved less clearly and the pain did not decrease.
The efficacy criteria for aiding sleep are divided into three classes: obvious effect, effective and ineffective.
After three weeks of use
The effect is shown: the user can fall asleep within 30 minutes after getting on the bed to turn off the light, and can fall asleep after getting up to night. No drowsiness and hypodynamia in the daytime.
The method is effective: the time to fall asleep is more than 30 minutes, and the time to fall asleep after taking off night is more than 20 minutes. There is little drowsiness and weakness in the daytime.
Invalidation: the person cannot fall asleep within 30 minutes after getting on the bed to turn off the light, and falls asleep difficultly after getting off the night. Drowsiness and weakness in the daytime.
The results of the cases show that the application agent has obvious effect and total effective rate up to 100%, and the application agent has good treatment and health care effects, convenient use and reliable curative effect.
Table 1 statistics of 160 patients' efficacy observations
Note that: among 47 cases of soft tissue injury with detumescence and analgesia, the number of cases of smearing treatment is 22, and the number of cases of foot bath treatment is 25.
The foregoing description is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and any simple modification, variation and equivalent structural changes of the above embodiment according to the technical matter of the present invention still fall within the scope of the technical solution of the present invention.
Claims (8)
1. The foot Chinese and western medicine combination is characterized by comprising the following raw materials in parts by weight: 7-10 parts of wormwood, 8-10 parts of dandelion, 5-10 parts of corn silk, 8-10 parts of mint, 8-10 parts of honeysuckle, 8-10 parts of bletilla striata, 5-10 parts of ginger, 7-10 parts of cortex moutan, 8-10 parts of garden balsam stem, 8-10 parts of stephania tetrandra, 12-15 parts of nux vomica and 5-10 parts of clove.
2. The combination according to claim 1, wherein the combination is in the form of a spread or decoction.
3. The combination according to claim 2, wherein when the dosage form of the combination is a spread, the raw materials of the combination further include: 10 parts of glycerin, 10 parts of vitamin E, 5 parts of sodium bicarbonate, 10 parts of sodium sulfate, 5 parts of sodium lauryl sulfate, 1 part of zinc oxide, 10 parts of yellow vaseline and 10 parts of essence.
4. The combination according to claim 2, wherein when the combination is in the form of a decoction, the combination further comprises: 10 parts of mineral salt, 10 parts of glycerin, 15 parts of vitamin E, 10 parts of sodium bicarbonate, 10 parts of sodium sulfate, 10 parts of sodium lauryl sulfate and 10 parts of essence.
5. The combination foot chinese and western medicine of claim 4 wherein said mineral salt is a borate salt.
6. A method for preparing the combination of a foot-use Chinese medicine and a western medicine according to any one of claims 3 to 5, which is characterized in that,
when the dosage form of the combination of the Chinese and western medicines for foot is a coating agent, the method comprises the following steps: pulverizing the raw materials, soaking the pulverized raw materials in ethanol solution containing glycerol, vitamin E, sodium bicarbonate, sodium sulfate, sodium lauryl sulfate, zinc oxide, yellow vaseline and essence for 7-30 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain a coating agent;
when the dosage form of the foot Chinese and western medicine combination is decoction, the method comprises the following steps: pulverizing the raw materials, soaking the pulverized raw materials in ethanol solution containing glycerol, vitamin E, sodium bicarbonate, sodium sulfate, sodium laurylsulfate and essence for 7-30 days, removing residues, precipitating, filtering to obtain filtrate, and packaging the filtrate to obtain decoction.
7. The method of claim 6, wherein the ethanol solution has a volume concentration of 55%.
8. The method according to claim 6, wherein the ratio of the volume of the ethanol solution to the weight of the drug substance is (4-10): 1, wherein the volume of the ethanol solution is in mL and the weight of the drug substance is in g.
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