CN1175857C - Medicine for preventing and curing cerebrovascular dementia - Google Patents

Abstract

The present invention discloses a medicine for preventing and treating cerebral vascular dementia. The raw materials for preparing the medicine comprise 3 to 9 g of ginseng, 3 to 9 g of notoginseng, 3 to 9 g of Chinese magnolivine fruit, 6 to 15 g of asiatic cornelian cherry fruit, 10 to 30 g of prepared rehmannia root, 10 to 20 g of prepared fleece flower root, 5 to 10 g of Chinese caterpillar fungus, 10 to 15 g of stir-baked cortex eucommiae, 1 to 3 g of antler, 1.5 to 3 g of leech, 5 to 10 g of stone, 3 to 10 g of thinleaf milkwort root, 3 to 15 g of danshen root and 10 to 30 g of tortoise plastron. The medicine improves the oxygen absorbing capability of a patient at normal pressure by the properties of traditional Chinese medicines, promotes meninx microcirculation, and enhances immunizing power and memory functions. The medicine not only has a favorable effect for treating cerebral vascular dementia, and but also can prevent the cerebral vascular dementia.

Description

A kind of medicine that is used to prevent and treat vascular dementia

Affiliated technical field

The invention belongs to a kind of Chinese medicine, relate generally to a kind of medicine that is used to prevent and treat vascular dementia.

Background technology

At present, vascular dementia is to cause one of old three invalid big diseases.It is about 5% that the old people of China more than 60 years old suffers from prevalence of dementia, and vascular dementia account for whole old diseases slow-witted more than 60%, it is harm person old people's life and health seriously.In 20 end of the centurys, the milestone that Neurology Department is treated courageous and upright dementia of brain and alzheimer disease is set up in the appearance of cerebrolysin.To so far, cerebrolysin, many dais of brain preparation remain the choice drug of treatment vascular dementia, to patients with mild, have certain curative effect.Then to patient with severe symptoms and undesirable, and its expense costliness, make patient be difficult to bear, thereby stopped treatment is that this state of an illness is more and more heavier, still be difficult to popularize, and late result is most of undesirable.

Summary of the invention

Purpose of the present invention promptly is to propose a kind of medicine that is used to prevent and treat vascular dementia, utilize the characteristic of Chinese medicine, improve patient's normal pressure and the oxygen ability, promote the meninges microcirculation, enhancing immunity and memory function, it is respond well not only to treat vascular dementia, and prevention of brain vascular dementia well.

Purpose of the present invention adopts following technical scheme to realize: it is formulated by Chinese medicine Radix Ginseng, Radix Notoginseng, Fructus Schisandrae Chinensis, Fructus Corni, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Cordyceps, Cortex Eucommiae (parched), Cornu Cervi Pantotrichum, Hirudo, Rhizoma Acori Graminei, Radix Polygalae, Radix Salviae Miltiorrhizae, Carapax et Plastrum Testudinis; The component content of compounding pharmaceutical is Radix Ginseng 3-9g, Radix Notoginseng 3-9g, Fructus Schisandrae Chinensis 3-9g, Fructus Corni 6-15g, Radix Rehmanniae Preparata 10-30g, Radix Polygoni Multiflori Preparata 10-20g, Cordyceps 5-10g, Cortex Eucommiae (parched) 10-15g, Cornu Cervi Pantotrichum 1-3g, Hirudo 1.5-3g, Rhizoma Acori Graminei 5-10g, Radix Polygalae 3-10g, Radix Salviae Miltiorrhizae 3-15g, Carapax et Plastrum Testudinis 10-30g.

The preparation of said medicine adopts traditional method to make close ball, the heavy 3.5g of every ball.

Radix Ginseng in the described medicine, nature and flavor are sweet, and little hardship, tepor are returned spleen, lung meridian.Have that strongly invigorating primordial QI, multiple arteries and veins take off admittedly, invigorating the spleen and replenishing QI, promote the production of body fluid, calm the nerves, effect such as Fructus Alpiniae Oxyphyllae.

Radix Notoginseng, nature and flavor are sweet, and little hardship, temperature are returned liver stomach warp.Can the warm stasis of blood stop blooding dissipating blood stasis hemostasis, subduing swelling and relieving pain.

Fructus Schisandrae Chinensis, lung, kidney, heart channel are returned in nature and flavor acid, sweet, warm.The nourishing kidney of astringing the lung, strengthening superficial resistance to stop perspiration, arresting seminal emission antidiarrheal, supplementing QI for promoting the production of body fluid, mind tranquilizing and the heart calming.Be used for chronic cough dyspnea due to deficiency, seminal emission, spontaneous perspiration, night sweat, chronic diarrhea, weak, the hepatitis of neural inner feelings.

Fructus Corni, nature and flavor are puckery, the acid temperature, return the Liver and kidney warp.The energy liver and kidney tonifying, the arresting seminal emission reducing urination, consolidating channel for hemostasis, arresting sweating take off admittedly.

Radix Rehmanniae Preparata, sweet, the tepor of nature and flavor is returned liver, kidney channel.The beneficial blood YIN nourishing of energy, vital essence replenishing and marrow benifiting.

Radix Polygoni Multiflori Preparata, nature and flavor are sweet, puckery, tepor, return the Liver and kidney warp.Have enrich and benefit essence and blood, detoxifcation, loosening bowel to relieve constipation, disappear the pain effect.

Cordyceps, nature and flavor are sweet flat, return lung, kidney channel.Effect with kidney tonifying tonifying the lung, hemostasis and phlegm.

Cortex Eucommiae (parched), nature and flavor are sweet, warm, return liver, kidney channel.Energy invigorating the liver and kidney, bone and muscle strengthening, solid nausea.

Cornu Cervi Pantotrichum, nature and flavor are sweet, salty, warm, return liver, kidney channel.The young kidney yang of energy, benefiting essence-blood, bone and muscle strengthening, Gu Chong appoints, holds in the palm sore.

Hirudo, nature and flavor hardship, salty, flat, tepor is returned Liver Channel.Can disappear by removing blood stasis.

Rhizoma Acori Graminei, nature and flavor suffering, hardship, temperature, GUIXIN, stomach warp.The sensible expectorant of energy, refreshment brain-strengthening, the appetizing of drying.

Radix Polygalae, nature and flavor suffering, hardship, tepor, GUIXIN kidney, lung meridian.Can calm the nerves Fructus Alpiniae Oxyphyllae, the sharp key that eliminates the phlegm, the medicinal powder for relieving pain knot.

Radix Salviae Miltiorrhizae, is slightly cold GUIXIN, Liver Channel at the nature and flavor hardship.The Eradicates stasis of blood of invigorating blood circulation, removing heat from blood detumescence, clearing away heart-fire for tranquillization.

Carapax et Plastrum Testudinis, nature and flavor are sweet, salty, cold, return liver, kidney channel.The energy nourishing YIN for suppressing the hyperactive YANG, the kidney tonifying bone strengthening, Gu the reinforcing the heart of nourishing blood is through only collapsing.

In the said medicine, with beneficial marrow and benefitting semens such as Carapax et Plastrum Testudinis, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the moon of nourishing the liver and kidney; Cornu Cervi Pantotrichum, beneficial marrow and benefitting semen is to help kidney yang; Invigorating the spleen and benefiting QI such as Radix Ginseng, Fructus Schisandrae Chinensis, strongly invigorating primordial QI is strengthened corticocerebral excitation, improves analysis ability, improves the emotion of the motility and the sleep of neural activity process, promotes the nucleic acid and the proteinic resynthesis of cell; Promoting tissue regeneration by removing blood stasis is stimulated the menstrual flow in blood stasis dispellings such as Radix Notoginseng, Radix Salviae Miltiorrhizae, Hirudo; The Radix Salviae Miltiorrhizae blood nourishing acupuncture-stimulating, the good merchantable brand for nourshing blood and promoting blood circulation improves peripheral circulation, improves the anoxia enduring power of human body under normal pressure and the low pressure condition, and ischemia due to the lobus posterior hypophyseos is had protective effect, can promote reparation and the regeneration organized; Radix Notoginseng has blood circulation promoting and blood stasis dispelling, stops blooding and do not stay the speciality of the stasis of blood; Tranquilization and refreshment such as Rhizoma Acori Graminei, Radix Polygalae, eliminate phlegm for resuscitation the damp eliminating appetizing; Especially with Kidney-Yin kidney-Yang in the energy the kidney invigorating such as Carapax et Plastrum Testudinis, Cornu Cervi Pantotrichum, training is root unit admittedly, activating QI hemopoietic, kidney tonifying, essence replenishing, replenishing the brain and spinal cord; Cordyceps, short, the Fructus Corni of Du, energy tonification lung, liver, kidney add marrow, bone and muscle strengthening, benefiting essence-blood, enhancing human body immunity function.All medicines are harmonious proper, and QI and blood is in harmonious proportion, the invigorating the liver and kidney of overflowing, life essence-filling, marrow-benefitting, logical QI and blood regulating, eliminating phlegm for resuscitation.It can improve the normal pressure hypoxia-bearing capability, promotes meninges microcirculation, enhancing immunity and memory function.Clinical practice is safe and effective, and toxic and side effects is little.Because the Chinese medicine cost is low, reduces patient's medical expense greatly.

The specific embodiment

The used raw material of preparation the present invention: Radix Ginseng 8g, Radix Notoginseng 5g, Fructus Schisandrae Chinensis 6g, Fructus Corni 10g, Radix Rehmanniae Preparata 20g, Radix Polygoni Multiflori Preparata 15g, Cordyceps 8g, Cortex Eucommiae (parched) 11g, Cornu Cervi Pantotrichum 2g, Hirudo 1.5g, Rhizoma Acori Graminei 6g, Radix Polygalae 3g, Radix Salviae Miltiorrhizae 10g, Carapax et Plastrum Testudinis 20g.Said medicine is made close ball through the Chinese medicine traditional handicraft, the heavy 3.5g of every ball.

The present invention is through clinical observation and experiment, and the result is as follows:

1, clinical choosing example: meeting International Classification of Diseases (ICD-10) diagnostic criteria is the diagnostic criteria of light moderate dementia, with reference to Chang Gu river Dementia scale (HDC), and (see " Journal of Traditional Chinese Medicine " the 32nd volume with " diagnosis of senile dementia and the efficacy assessment standard " that revise in Beijing whole nation senile dementia special topic academic conference discussion May nineteen ninety, the 56th page of 1991 the 2nd phase) be foundation, cooperate imageology MRI or CT diagnosis that 544 routine Patients with Vascular Dementia are randomly drawed 300 examples.

2, clinical data: among the 300 routine patients, male's 180 examples wherein, women's 120 examples, age 30-88 year, 63.07 years old mean age; Pathology is the shortest 1 month, and is the longest 6 years; 101 examples that the state of an illness is slight; Moderate 168 examples, severe 31 examples.

3, Therapeutic Method: take pill of the present invention, early, after the supper each 1.

4, therapeutic effect: 86 examples that are almost recovered (28.7%), produce effects 106 examples (353%), effective 82 examples (27.4%), invalid 26 examples (8.6%), total effective rate 913%.

Model case:

1, Li Yumin, the man, 65 years old, first worker of carrier of Luoyang City, Henan, hypertension history 10 years, in January, 1996 sudden onset, left limb paralysis, 8 months mute, the multi-treatment effect is not good enough, so the prescription on individual diagnosis of coming.

CT shows: left side substrate old cerebral infarction, bilateral brain hang down and enlarge, and twoly split pond expansion, two volume, subarachnoid space and increase plug.Conclusion: brain atrophy, old cerebral infarction.The patient has a dull expression on one's face, and hypomnesis, forgetful can not be walked, and through each big medical therapy, symptom does not subtract, urgent micturition frequent micturition over 8 months, and feed is choked and is stung, and the stiff tongue sialorrhea be can't take care of oneself.Take the agent of this pill after 20 days, the patient can descend ground movable, after 30 days, the more preceding improvement of language, is choked and is stung disappearance, after 50 days at sialorrhea, it is normal substantially that limbs recover, hypermnesia, it is invalid to react, the eyes are bright and piercing, and can write mail, go up downstairs substantially freely, aftersensation was the same with the normal person in 60 days, 10 kilometers of the row of going out by bike.

Continue to take the agent of this pill, treat half a year, energetic, five, six floors are often participated in social activity up and down.Go out often by bike.On December 20th, 1997, and CT checks demonstration, the broadening of bilateral subarachnoid space, and brain matter no abnormality seen changes, and centerline construction is placed in the middle.Conclusion: circumscribed cerebral atrophy, calendar year 2001 JIUYUE CT check once more on the 10th: Fructus Citri tangerinae note: circumscribed cerebral atrophy.So far do not see recurrence.

2, poplar makes a noise, man, 58 years old, Red Hill township, suburb, Luoyang City peasant.On October 7th, 1998, confused bloated, the astasia, top-heavy of excuse, as step on the sponge sense, 3 years, come to go to a doctor.

The patient is February nineteen ninety-five, and left limb is weak, numb.Transference cure after treating.In October nineteen ninety-five, dizziness and distending sensation of the head, top-heavy, walking shakiness occur, as step on the sponge sense.In February, 1996, dizziness and distending sensation of the head aggravation, feel sick, vomiting, walking, astasia, lean forward, hypomnesis, forget what to write when actually writing, do not think to effect a permanent cure, see that the acquaintance is obscure word, frequent micturition, out of control sometimes.February 20, CT shows: left and right sides basal ganglia region is seen point-like low-density focus many places, two frontal lobes, and cortex brain ditch is deepened, broadening, and centerline construction is placed in the middle.Conclusion: multiple crack property cerebral infarction, brain piston, passages through which vital energy circulates live peaceful, cerebrolysin, XUESAITONG, brain association is logical etc., and 40 days symptoms of Drug therapy do not subtract, and body is general, lusterless complexion, one's eyes are lustreless, and the table bosom is indifferent, and extremity are not warm, dysstasia, walking is unstable, leans forward, and needs the post cane.

Take the agent of this pill after 15 days, extremity change temperature, dizziness and distending sensation of the head, feel sick, vomiting alleviates, and are clearheaded after 30 days, feel sick, vomiting disappears, and diet increases, before walking is changeed steadily, after 45 days, smooth running and effectively, and throw away cane.After two months, memory increases, can read a book read the newspaper, two just normal, after three months, trot out feasible about 5 kilometers.When consolidating curative effect, continue treatment six months.

In July, 1999 oneself is visiting, says and can participate in field labour, goes out feasible by bike often about 30 kilometers.In October, 1999, the CT check showed: the brain material density is normal, system's no abnormality seen in the brain, and two frontal lobes district, the slight broadening of cortex brain ditch, middle body structure is placed in the middle.Conclusion: the slight brain atrophy of two frontal lobes.

Claims (1)

1, a kind of medicine that is used to prevent and treat vascular dementia is characterized in that: the raw material that is used for compounding pharmaceutical is: Radix Ginseng 3-9g, Radix Notoginseng 3-9g, Fructus Schisandrae Chinensis 3-9g, Fructus Corni 6-15g, Radix Rehmanniae Preparata 10-30g, Radix Polygoni Multiflori Preparata 10-20g, Cordyceps 5-10g, Cortex Eucommiae (parched) 10-15g, Cornu Cervi Pantotrichum 1-3g, Hirudo 1.5-3g, Rhizoma Acori Graminei 5-10g, Radix Polygalae 3-10g, Radix Salviae Miltiorrhizae 3-15g, Carapax et Plastrum Testudinis 10-30g.